auditor s procedures in response to assessed risks
Báo cáo khoa học: "Central nervous system Toll-like receptor expression in response to Theiler''''s murine encephalomyelitis virus-induced demyelination disease in resistant and susceptible mouse strains" ppsx
... during TMEV-IDD remains to be elucidated, but reinforces TLRs as possible culprits in the initiation of self-immune processes in the brain This could encourage the investigation of TLRs as possible ... can bind elements of the TMEV Our results show this is more obvious in a TMEV-susceptible versus a TMEV-resistant mouse strain Expression of bacterial component-specific TLRs in TMEV infected SJL/J ... the host immune system in the CNS to the point that a host response to myelin elements occurs It is well established that TLRs recognize components of viruses and are involved with the initiation...
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Leaching of arsenic in response to organic matter contamination in groundwater treatment practice
... of arsenic and iron in the presence of organic matter in AIRU feed water was investigated under dosage -response observations in multiple sets of laboratory reactors In case of simulated wastewater ... performance in AIRU was also studied The concentration of arsenic with effluent water in this case was found to be less in comparison to previously used simulated wastewater, possibly due to having fewer ... proposed that aqueous organic-metal complexes may, in turn, associate strongly with dissolved arsenic anions, presumably by metal-bridging mechanisms, diminishing the tendencies of such anions to...
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WRITING IN RESPONSE TO LITERATURE
... Whitman, she does not proclaim success She simply suggests that “Her message is committed to hands she cannot see” (her audience, perhaps years in the future) and she asks that Nature s message, interpreted ... your essay with an introductory paragraph that asserts a thesis statement Similar to the thesis statements we have discussed in the previous chapters, a thesis statement for poetry analysis, for ... most high stakes tests for high school graduation you will be asked to read short fiction such as the short stories above and respond to short answer questions and then short essay questions The...
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Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf
... were observed in female controls in response to oxygen stress We propose that estrogen-mediated mitochondrial biogenesis may also be implicated in this process In agreement, recent studies reported ... mitochondrial respiratory functional analyses were only performed using fatty acids as substrate Additional studies measuring mitochondrial respiratory function using a more representative substrate ... glucose oxidation should provide additional insights into this interesting question Conclusions In summary, we have identified a novel metabolic gene switch (decrease in fatty acid utilization, increase...
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Tài liệu Báo cáo khoa học: Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells pptx
... initiations first produce homogeneously sized small daughter strands, which subsequently grow homogeneously to longer sizes, thus causing a synchronous shift of growing DNA chains to higher S- values Figure ... [3,16] In the course of investigating several cell lines (see Discussion), we came across the human bladder carcinoma cell line T24, which is easily arrested in G1 by starvation [17] Using this cell ... by Triton buffer was high in the same cells These results clearly show that the PCNA staining is colocated with the BrdU staining and this again signifies that PCNA is only bound to chromatin portions...
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Báo cáo khoa học: DNA-binding characteristics of the regulator SenR in response to phosphorylation by the sensor histidine autokinase SenS from Streptomyces reticuli doc
... 10.1371/journal.pcbi.0020143 Hutchings MI, Hoskisson PA, Chandra G & Buttner MJ (2004) Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor ... assumption that phosphorylation of SenR by SenSP alters its DNA-binding characteristics Discussion The designed cloning procedures allowed us to obtain the cytoplasmic domain of SenS carrying ... comprises motifs that are related to the SenR-binding sites (II and III) (data not shown) indicates that these homologous systems are also autoregulated According to these findings, it could be assumed...
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Báo cáo khoa học: Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids docx
... Glucose was measured in haemolysed blood samples [33] Statistics Values are given as means ± S. E.M Statistical significance was calculated using Student s t-test for paired or unpaired samples as indicated ... glycerolphosphate acyltransferase, nitric oxide synthase, hormone-sensitive lipase, creatine kinase, glycogen synthase, phosphofructokinase 2, ceramide synthesis, glucose uptake, apoptosis, insulin receptor ... within AMPK a-subunits [7] Apart from being blocked by the phosphatidylinositol 3-kinase inhibitor wortmannin, no other details of this insulin process are known A novel and physiologically interesting...
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Can’t Shake that Feeling: Event-Related fMRI Assessment of Sustained Amygdala Activity in Response to Emotional Information in Depressed Individuals pptx
... have inverse relationships to amygdala activity The following sections outline methods used for assessing this sustained activity and predictions for depressed individuals Assessment of Sustained ... assess rumination These include the Response Styles Questionnaire (RSQ; a 71-item inventory with a rumination subscale assessing the frequency of thoughts about one s symptoms of depression [RSQ-rum]; ... ROIs corresponding to modeled areas Planned contrasts suggested that, as hypothesized, depressed individuals showed sustained responses for negative information versus neutral information, in...
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Báo cáo khoa học: Gene expression in response to endoplasmic reticulum stress in Arabidopsis thaliana ppt
... translocon subunits by ER stress in Arabidopsis suggests that an ERAD system similar to those of yeast or mammalian cells may remove misfolded proteins produced in the ER of plant cells This is supported ... genes Increase in putative SEL-1L due to ER stress in Arabidopsis In yeast and mammalian cells, the HRD1 ⁄ HRD3 (SEL-1L) ubiquitination system coupled to protein degradation by 2 6S proteasomes is ... Unfolded protein response genes in Arabidopsis vesicle trafficking ⁄ transport, vacuolar protein sorting, cell wall biogenesis, and lipid ⁄ inositol metabolism In comparison with those of yeast, the...
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Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... MEK1 ⁄ inhibition, in several other studies [44–46] It is interesting to note that in all cases MEK inhibitor-induced BIM expression alone was not sufficient to induce a dramatic increase in cell ... because other BCR–ABL inhibitors increase BIM expression, it is surprising that MK-0457 does not; does this suggest that the additional inhibitory activity against aurora kinases antagonizes BIM ... pronounced increases in apoptosis were only observed when MEK inhibition was combined with serum deprivation [41,42] This suggests that loss of other serum-dependent survival pathways, such as the phosphoinositide...
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Báo cáo khoa học: Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus – the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress pot
... release of both CHHs seems to be sensitive to dissolved oxygen in seawater, suggesting an adaptive role A single SG in the ES of Cal sapidus contains two isoforms of CHH The molecular mass difference ... during summer, in combination with the changes in salinity, are associated with high mortality in this species [25–27] In view of CHH involvement in response to stress in other crustacean species, ... immunohistochemistry studies show that the intrinsically staining cells are responsible for PO-CHH synthesis The staining patterns are similar to those of Car maenas, in that most cells (approximately...
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Bank Behavior in Response to Basel III: A Cross-Country Analysis doc
... subject to the extra capital requirements Consequently, LCFIs would lose business to less systemic firms if they choose to raise loan rates On the other hand, investors would find smaller less ... Their estimate is basis points for a percentage points increase in the capital to equity ratio so that basis points would result from a 1.3 percentage points increase in the capital to asset ratio ... margin, calculated as the difference between interest income (II) and interest expense (IE); NII is non–interest income; SG is security gains (losses); NIE is non–interest expense, PLL is provisions...
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Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx
... cells) and CasWt cells (generated by transfecting CasKo cells with wild-type Cas) Cas expression in CasWt cells was similar to that in Balb3T3 cells, and Cas was absent in CasKo cells (Fig 1A) As ... response to wound healing Src kinase inhibition disrupts polarization of migrating cells The Src tyrosine kinase phosphorylates Cas to promote cell migration [18] We employed a Src kinase inhibitor ... Cas for cell polarization, we used small interfering RNA (siRNA) to knockdown Cas expression in Balb3T3 cells As shown in Fig 4A, transfection with Cas siRNA effectively suppressed Cas expression...
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Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... experiments using hDlg mutated at different p38c phosphorylation sites or using several kinase inhibitors, including the general kinase inhibitor staurosporine, demonstrated that under these conditions ... Drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy Int J Cancer 111, 373–380 10 Lee SS, Weiss RS & Javier ... hDlg is degraded in response to osmotic stress (Fig S3 ), hDlg was found mostly in areas of cell–cell contact and a substantial and gradual loss from the membrane was observed after osmotic shock...
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Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... function of SEP53 in response to DCA, calcium release suppressed by SEP53, and its highly conserved calcium-binding domain Discussion Tissue-specific stress responses control cell injury, disease development, ... proteomics’ approach The first studies indicated that ex vivo stressed squamous cells in organ culture did not synthesize the classic stressed-induced protein HSP70 after stress, suggesting a novel ... unique stress responses presumably due to unique microenvironmental pressures The mechanisms underlying this tissue and cell-specific control on rates of stress protein induction in metazoans is not...
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Báo cáo khóa học: Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters pdf
... protease inhibitor studies these proteinases fall into two main classes: (a) elastase-like serine proteinases as for c-kit receptor ligands KL-1 and KL-2 [23] and (b) metalloproteinases as for ... hand, some cytokines and their receptors, such as IL-6 and its receptor, can act as potent agonists on cells [42] Cleaved membrane proteins are also involved in various diseases, such as Alzheimer ... plasma by cell bound LDL-R This occurs in the case of soluble growth factor receptors and soluble cytokine receptors, where the soluble receptors have been shown to act as antagonists by binding...
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Báo cáo khoa học: BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells pdf
... change First, we assessed whether there was a change in TRAIL expression in MDAMB-468 cells in response to hypoxia by analyzing its cell surface expression Immunofluorescent analysis of TRAIL in nonpermeabilized ... KillerTRAIL and assessed for apoptosis by flow cytometry and caspase-3 activity Neither assay Fig TRAIL induces apoptosis in breast cancer cells MDA-MB-468 cells were treated with (A) increasing concentrations ... processes, we assessed the ability of hypoxia to induce apoptosis in our model systems Approximately 4% of MDA-MB-468 cells were present within the subdiploid population of cells as determined...
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Báo cáo khoa học: Irreversible cross-linking of heme to the distal tryptophan of stromal ascorbate peroxidase in response to rapid inactivation by H2O2 ppt
... chlorolasts FEBS Lett 428, 47–51 Yoshimura K, Yabuta Y, Ishikawa T & Shigeoka S (2000) Expression of spinach ascorbate peroxidase isoenzymes in response to oxidative stresses Plant Physiol 123, ... MS ⁄ MS data were acquired and processed automatically using MassLynx 4.0 software (Waters Co.) Acknowledgements We thank Ms Yuki Shinzaki for technical assistance This study was supported in ... has not been reported to cross-link to heme Thus, H2O2-mediated cross-linking in perxoxidases other than tsAPX, if it occurs, may be much slower Why the heme rapidly forms a cross-link in tsAPX...
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Báo cáo khoa học: Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure doc
... xenobiotic detoxification One, the glutamine synthetase gene was previously shown to be associated with the response of various organisms to pesticide exposure The response seen in our libraries was that ... was 780 mgÆL)1 in Daphnia) [33] The LC50 for oyster 393 Oyster response to pesticide exposure A Tanguy et al Table Summary of the results of expression studies in the two tissues used in SSH ... results were observed in previous reports studying the effect of other stress such as hydrocarbons [22] or parasite infection [47], showing that any source of stress generates an increase in energy...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25