... viral oncogene homolog Human has three RAF: CRAF, BRAF, and ARAF RAS: rat sarcoma viral oncogene homolog Human has three RAS: HRAS, NRAS, and KRAS (KRAS 4A and KRAS4B proteins arise from alternative ... genomes has already provided an invaluable insight into activating mutations and surrogate signalling pathways sustaining deregulated proliferation, invasiveness and resist‐ ance to apoptosis as ... Cristina Sini, Paolo Antonio Ascierto, Amelia Lissia and Antonio Cossu Chapter Low-Penetrance Variants and Susceptibility to Sporadic Malignant Melanoma 59 G Ribas, M Ibarrola-Villava, M.C Pe a- Chilet,...
Ngày tải lên: 18/02/2014, 04:20
... use of “anfetaminas” was 0.1% and use of metanfetaminas was
Ngày tải lên: 06/03/2014, 09:21
Addictions – From Pathophysiology to Treatment Edited by David Belin pdf
... 186 0s, almost as soon as it was synthesised A few years after its synthesis by Richard Willstätter in 1898 (6), cocaine appeared in cigarettes, ointments, nasal sprays, and tonics The most popular ... mechanisms As instrumental reinforcers they strongly encourage behaviours that lead to the availability of a drug, a process subserved by stimulus-response associative mechanisms (instrumental ... drugs but also for natural rewards such as food, water, sexual partner and novelty [10] Based on a plethora of studies, it is widely accepted that increased dopamine transmission is necessary...
Ngày tải lên: 16/03/2014, 21:20
Football Traumatology Current Concepts: from Prevention to Treatment doc
... general and segmental assessment of organs and apparatus; and special attention to the cardiovascular, respiratory, and locomotor systems Additional investigations can be performed in case of ... the athletes start playing for the association In case of an athlete s transfer to another sport association, the physician must update the health card at least days before the transfer and must ... professional competitive sports practice Sports associations are obliged to issue health cards, and it is the physician of the sport association who must fill in and regularly update the cards as...
Ngày tải lên: 24/03/2014, 02:21
EVALUATION OF CAPACITY TO CONSENT TO TREATMENT AND RESEARCH doc
... roles when asked to assess a patient s clinical state (‘‘Is this patient depressed?’’ ‘‘Why is this person delirious?’’) as well as to assess that patient s decision-making capacity to consent ... standard in such a situation is discussed in chapter 6, and a systematic method of assessing appreciation is outlined in chapter Pillars of Modern Practice of Treatment Consent Capacity Assessment ... agencies, court clinics, and hospitals in which litigants are assessed may also use some of the books in this series to establish expectancies for evaluations performed by professionals in their agencies...
Ngày tải lên: 29/03/2014, 00:21
Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf
... analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasisrelated proteins J ... Isidoro A, Casado E, Redondo A, Acebo P, Espinosa E, Alonso AM, Cejas P, Hardisson D, Fresno Vara JA, Belda-Iniesta C, et al: Breast carcinomas fulfill the Warburg hypothesis and provide metabolic ... dead (red stained) cells was calculated from 10-20 different randomly selected fields for each condition assayed Methods Cell cultures and treatments Caspase activity assays Human colorectal carcinoma...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" ppt
... analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasisrelated proteins J ... Isidoro A, Casado E, Redondo A, Acebo P, Espinosa E, Alonso AM, Cejas P, Hardisson D, Fresno Vara JA, Belda-Iniesta C, et al: Breast carcinomas fulfill the Warburg hypothesis and provide metabolic ... dead (red stained) cells was calculated from 10-20 different randomly selected fields for each condition assayed Methods Cell cultures and treatments Caspase activity assays Human colorectal carcinoma...
Ngày tải lên: 20/06/2014, 03:20
báo cáo hóa học:" From HIV diagnosis to treatment: evaluation of a referral system to promote and monitor access to antiretroviral therapy in rural Tanzania" doc
... J, Zaba B, Changalucha J, Kalluvya S, Urassa M: Barriers to accessing antiretroviral therapy in Kisesa, Tanzania: a qualitative study of early rural referrals to the national program AIDS Patient ... Dakar 2008 Nsigaye R, Mbata D, Wringe A, Clark B, Roura M, Zaba B, Urassa M: From HIV diagnosis to treatment: Implementing a referral system to monitor access to ART in Kisesa Ward Dar es Salaam ... cohort in Tanzania XV International Conference on AIDS and STIs in Africa (ICASA) Dakar 2008 Roura M, Wringe A, Busza J, Nhandi B, Mbata D, Zaba B, Urassa M: "Just like fever": a qualitative study...
Ngày tải lên: 20/06/2014, 08:20
báo cáo hóa học:" A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries" pptx
... the study, participated in data cleaning and data analysis, and was the lead author on this paper ED performed data cleaning and data analysis SM contributed to data analysis, writing of the manuscript, ... than 60 kilogrammes (kg) [18,19] We provided estimates of producer market share for all ARVs, but also calculated market share among three ARV market niches: paediatric ARVs (all classes), adult ... Indian manufacturers in an environment largely void of intellectual property barriers [23,24] Countries across sub-Saharan Africa with high HIV/AIDS burdens, as well as India, are heavily reliant...
Ngày tải lên: 20/06/2014, 08:20
DYSLIPIDEMIA FROM PREVENTION TO TREATMENT potx
... Saravane Chapter 18 Dyslipidemia Induced by Stress 367 Fernanda Klein Marcondes, Vander José das Neves, Rafaela Costa, Andrea Sanches, Tatiana Sousa Cunha, Maria José Costa Sampaio Moura, Ana ... for Cardiovascular Disease 279 Telmo Pereira Chapter 15 Dyslipidemia and Cardiovascular Disease 303 Hossein Fakhrzadeh and Ozra Tabatabaei-Malazy Chapter 16 Cardiovascular Risk in Tunisian Patients ... Atherosclerosis and Other Diseases Vassilis Zannis, Andreas Kateifides, Panagiotis Fotakis, Eleni Zanni and Dimitris Kardassis 173 Chapter 10 Disrupted VLDL Features and Lipoprotein Metabolism in Sepsis...
Ngày tải lên: 27/06/2014, 13:20
Báo cáo y học: " Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden" docx
... cardiovascular diseases, any malignancies, chronic pulmonary diseases, and diabetes according to ICD (International Statistical Classification of Diseases and Related Health Problems) or 10 diagnosis ... on a five-grade scale; HAQ, health assessment questionnaire; MTX, methotrexate; VASglobal, visual analogue scale for general health; VASpain, visual analogue scale for pain showed significantly ... patient-scored visual analogue scale for pain (VASpain) and general health (VASglobal), physician 's global assessment of disease activity on a five-grade scale (EVALglobal), 28 tender and swollen joint...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo khoa học: " Does Intensity Modulated Radiation Therapy (IMRT) prevent additional toxicity of treating the pelvic lymph nodes compared to treatment of the prostate only?" ppt
... published by Letschert et al.[23] was applied Plan-PO and plan-WP were compared using student 's ttest For statistical analysis Statistica 6.0 (Statsoft, Tulsa, USA) was utilized Differences were ... Phys 2005, 61(3):695-701 Vargas CE, Demanes J, Boike TP, Barnaba MC, Skoolisariyaporn P, Schour L, Gustafson GS, Gonzalez J, Martinez AA: Matched-pair analysis of prostate cancer patients with a ... whereas no risk was calculated using updated tolerance data [22] based on Letschert et al [23] These low risk estimations for rectal, bladder and small bowel toxicity are remarkable in consideration...
Ngày tải lên: 09/08/2014, 09:22
báo cáo khoa học: "Apoptosis in cancer: from pathogenesis to treatment Rebecca SY Wong" pps
... diseases such as Alzheimer s disease and Parkinson s disease Cell death that occurs in heart diseases such as myocardial infarction remarkably similar across cell types and species [11,12] Usually several ... activation of a series of caspases The upstream caspase for the intrinsic pathway is caspase while that of the extrinsic pathway is caspase The intrinsic and extrinsic pathways converge to caspase ... Devarajan E, Sahin AA, Chen JS, Krishnamurthy RR, Aggarwal N, Brun AM, Sapino A, Zhang F, Sharma D, Yang XH, Tora AD, Mehta K: Downregulation of caspase in breast cancer: a possible mechanism...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo y học: "soriatic arthritis: Pathogenesis and novel immunomodulatory approaches to treatment" doc
... uncomplicated psoriasis [8] Some of these associations may be confounded by linkage disequilibrium HLA-B27 has been associated with spinal disease in which radiological sacroiliitis is present A symmetric ... play a role in the vascular responses found in psoriasis [80] A phase II trial in psoriasis showed some improvement in patients' PASI as well as in histological responses [81] IL-1, many of the activities ... progression of joint erosions in early PsA [18] A meta-analysis showed the TNFα-238 variant in Caucasian PsA patients was a significant risk factor for PsA [19] A recent study pointed to Cw6 and...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "Longitudinal changes in HIV-specific IFN-γ secretion in subjects who received Remune™ vaccination prior to treatment interruption" pot
... Statistical analyses Data were analyzed by using GraphPad InStat statistical software, version 3.06 [(2003) GraphPad Software, San Diego, California, USA] Two-tailed nonparametric Wilcoxon matched-pairs ... quantification Plasma viremia was determined using the Roche Amplicor Assay (Roche Diagnostics, Mississauga, Ontario, Canada) with a detection limit of 500 HIV-1 RNA copies/ml of plasma Samples falling ... Epstein-Barr virus (EBV)-transformed B cell lines using the QIAamp DNA blood kit (Qiagen, Mississauga, Ontario, Canada) Each patient was typed for HLA class I alleles using 95 primer sets amplifying...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "Recurrence of suicidal ideation due to treatment with antidepressants in anxiety disorder: a case report" docx
... U .S and European regulatory agencies issued warnings about a possible suicide risk with antidepressant use in pediatric patients, was associated with increases in suicide rates in children and ... suggests that the increased use of SSRIs is related to decreased suicide rates whereas TCA prescriptions were related to increased suicide rates [10] On a similar point, a retrospective analyses of ... relationship between prescriptions of SSRIs and suicide rates suggests that the decrease of SSRI prescriptions for children and adolescents, both in the United States and the Netherlands, after...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: " Lower lid entropion secondary to treatment with alpha-1a receptor antagonist: a case report" pdf
... iris syndrome associated with tamsulosin J Cataract Refract Surg 2005, 31:664-673 Cheung CMG, Awan MAR, Sandramouli S: Prevalence and clinical findings of tamsulosin-associated intra-operative ... has also been documented to cause the intra-operative floppy iris syndrome (IFIS) [2] It is believed that tamsulosin blocks the iris dilator muscle and this constant receptor blockade results ... soon after commencing tamsulosin Page of Received: 22 October 2009 Accepted: March 2010 Published: March 2010 References Abrams P, Schulman CC, Vaage S: Tamsulosin, a selective a1 cadrenoceptor antagonist:...
Ngày tải lên: 11/08/2014, 11:23
báo cáo khoa học: " Assessing the spatial distribution of methadone clinic clients and their access to treatment" ppsx
... http://www.harmreductionjournal.com/content/7/1/14 Fotheringham AS, Brunsdon C, Charlton M: Quantitative Geography: Perspectives on Spatial Data Analysis London: SAGE Publications; 2000 Narcotics Division: ... recently established in response to the rising HIV threats in many Asian countries, the services have been established in Hong Kong before HIV/AIDS was discovered, back in the early 197 0s Overall, ... http://www.harmreductionjournal.com/content/7/1/14 Authors' contributions NSW conducted field study, collated the data, generated the maps, conducted all statistical analyses, and prepared the first draft of the manuscript...
Ngày tải lên: 11/08/2014, 18:20