... between 3 H3 and 2 H6 or H6¢ is assigned as well as the intramolecular NOE between 3 H3 and H1. Table 2. Intermolecular NOEs between West Nile virus (WNV) NS2B–NS3pro(K96A) and inhibitors 2 and 3. Protons ... half-filters (mixing time 120 ms) were used to suppress intramolecular NOEs of the protease and observe intermolecular NOEs. For unambiguous identification of intraligand NOEs, the experiment was also recorded ... intramolecular NOEs were observed for a sample at 0.7 mm, indicating an effec- tive molecular mass of > 500 Da. The possibility of self-association made it harder to interpret the inter- molecular...
Ngày tải lên: 07/03/2014, 02:20
Ngày tải lên: 30/03/2014, 01:20
Tài liệu OXFORD DICTIONARY OF Biochemistry and Molecular Biology REVISED EDITION Managing Editor Professor pdf
... activated, and inhibited by G-protein bc subunits. Types II (1088 amino acids) and IV (1064 amino acids) are calmod- ulin insensitive and activated by bc subunits; type II is found in brain and olfactory ... transcriptase and HIV protease, and drugs to prevent microbial infections of brain, respiratory and alimentary tracts and vagina. See HIV. acquired immunity or adaptive immunity immunity (active or pas- sive, ... p and A are phosphoric and adenosine residues, respectively, and a and n are small integers (a = 1, 2, or 3 and n commonly = 2, 3, or 4). Potent inhibitors of protein biosynthesis in vivo and...
Ngày tải lên: 23/01/2014, 07:20
Chemical bonding and molecular geometry( liên két hóa học và hình học phân tử)
... James) Chemical bonding and molecular geometry from Lewis to electron densities / R.i. Gillespie, P.L.A. Popelier. p. cm (Topics in inorganic chemistry) Includes bibliographical references and index. ISBN ... function L = - VZ p for L = 0 au (blue) and L = 0.60 au (orange). The L = 0.60 surface shows the charge concentations corresponding to the lone pairs on the sulfur atom and torodial charge concentrations ... alt=""
Ngày tải lên: 07/02/2014, 22:00
Chemical bonding and molecular geometry( liên kết hóa học và hình học phân tử)
... James) Chemical bonding and molecular geometry from Lewis to electron densities / R.i. Gillespie, P.L.A. Popelier. p. cm (Topics in inorganic chemistry) Includes bibliographical references and index. ISBN ... function L = - VZ p for L = 0 au (blue) and L = 0.60 au (orange). The L = 0.60 surface shows the charge concentations corresponding to the lone pairs on the sulfur atom and torodial charge concentrations ...
Ngày tải lên: 07/02/2014, 22:44
Tài liệu Báo cáo khoa học: Isolation and molecular characterization of a novel D-hydantoinase from Jannaschia sp. CCS1 docx
... standard molecular weight proteins. The flow rate was set to 0.8 mL Æmin )1 . The subunit molecular mass was also estimated by SDS–PAGE. Characterization and comparative analyses of HYD Js and ... puri, purified proteins; M, molecular weight standards. For the molecular weight stan- dards, the bands from top to bottom correspond to 116.0, 66.2, 45.0, 35.0, 25.0 and 18.4 kDa, respectively. Y. ... homotetramers [4]. Gel filtration analysis of native HYD Js indicated a molecular mass of about 253 kDa, and, as the subunit molecular mass of the His-tagged recombinant HYD Js was estimated to be 56...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khóa học: Determination by electrospray mass spectrometry and 1H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the iso-lacto-N-octaose core doc
... Conformational studies on the selectin and natural killer cell receptor ligands sulfo- and sialyl-lacto-N-fucopentaoses (SuLNFPII and SLNFPII) using NMR spectroscopy and molecular dynamics simulations. ... °Cat25°CÆmin )1 ,to220°Cat5°CÆmin )1 and to 310 °Cat10°CÆmin )1 . ES-MS Negative-ion ES-MS and CID MS/MS were carried out on a Micromass (Manchester, UK) Q-Tof mass spectrometer. Nitrogen was used as desolvation and nebuliser ... pattern and sequence analysis of underivatized oligosaccharides by com- bined MS/MS of singly and doubly charged molecular ions in negative-ion electrospray mass spectrometry. J. Am. Soc. Mass Spectrom....
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Biochemical and molecular characterization of hazelnut (Corylus avellana) seed lipoxygenases pdf
... C 6 and C 9 aldehydes (and the corresponding alcohol) were detected in all the samples and, similarly to the pattern of LOX expression and activity, their levels were higher in stage I seed and ... Hazelnut seeds contain reasonable levels of linoleic and linolenic acid (about 10 and 0.2%, respectively, of the total fatty acids) and hexanal and nonanal are among the most abundant volatile compounds ... the shelf life and the organoleptic features of hazelnut seeds, we carried out a study to characterize hazelnut lipoxygenases at the biochemical and molecular level. Materials and methods Plant...
Ngày tải lên: 21/02/2014, 00:20
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... 5¢-GCCCACACC AAT ACCTATGCG-3¢) and the 3¢ complementary primer 5¢-AT TAATGGCATGCTTTACCCGT-3¢.UsingthePCR products of agmatinase with the GfiAandCfiT substi- tutions in the coding and noncoding strands, respectively, and ... of B. caldovelox arginase (1cev), E. coli agma- tinase (AUH) and rat liver arginase (1rla). H, S, T and 3 stands for a-helix, strand, turn and 3 10 -helix. Conserved residues are marked by an asterisk. 5524 ... aligned with the sequences of 1CEV and 1RLA and pasted into the structural alignment. The alignment was then corrected by hand. Since the sequences of the two arginases and agmatinase greately differ...
Ngày tải lên: 21/02/2014, 01:21
MORPHOGENESIS THE CELLULAR AND MOLECULAR PROCESSES OF DEVELOPMENTAL ANATOMY pptx
... the caterpillar (was he so wrong?) and hence within the egg. At this point, reasonable scientific study was abandoned by many biologists and wish became the father of thought and the grandfather of observation: ... organisation is laid down, we also have to understand the interactions between the cells and the environment in which they operate. The range of cell and molecular mechanisms underpinning morphogene- sis ... autonomously reorganise themselves and change their shape. The mechanism operates in a wide variety of vertebrate and invertebrate tissues, but its mode of function and molecular basis remain unknown,...
Ngày tải lên: 05/03/2014, 11:21
Báo cáo " Anti-obesity and body weight reducing effect of Fortunella japonica peel extract fractions in experimentally obese mice " docx
... has effect on decreasing body weight and blood lipid, FDA). - Lot 1 and lot 6 did not treated with mandarin peel extracts were expressed the increase of body weight from 4% to 9.5%. Fig. ... with standard diet and drinking water ad libitum + Lot 2: Obese mice treated with ethanol fraction and drinking water ad libitum + Lot 3: Obese mice treated with chloroform fraction and drinking ... fraction and drinking water ad libitum + Lot 5: Obese mice treated with metformin (500mg/kg) and drinking water ad libitum + Lot 6: Obese mice fed normal diet and drink water (no treatment) and...
Ngày tải lên: 05/03/2014, 11:21
Báo cáo " Anti-obesity and body weight reducing effect of Docynia indica (Wall.) Decne fruit extract fractions in experimentally obese mice " doc
... cholesterol (LDL-c) and glucose concentrations to be 67.3%, 46.2 %, 28.6 % and 18.3 %, respectively as compared to ND mice. Our investigations show that anti-obesity and body weight reducing effects ... effect on decreasing body weight and blood lipid, FDA). Lot 1 did not treat with Docynia indica (W.) Decne fruit extracts were expressed the increase of body weight 11.9%. N.T.T. Loan ... glucose concentration. VNU Journal of Science, Natural Sciences and Technology 27 (2011) 125-133 125 Anti-obesity and body weight reducing effect of Docynia indica (Wall.) Decne fruit extract...
Ngày tải lên: 05/03/2014, 11:21
Lab Exercises in Organismal and Molecular Microbiology_2 doc
... and PstI double digest E EcoRI digest DNA standard λ-HindIII Sample: 54321Lane: Alexander−Strete−Niles: Lab Exercises in Organismal and Molecular Microbiology VI. Controlling the Risk and ... Exercises in Organismal and Molecular Microbiology VI. Controlling the Risk and Spread of Bacterial Infections 28. Skin Disinfection: Evaluating Antiseptics and Hand Sanitizers © The McGraw−Hill ... double-strength and 10 single-strength, and align into three rows of five in a test tube rack. Place the five double-strength Alexander−Strete−Niles: Lab Exercises in Organismal and Molecular Microbiology VI....
Ngày tải lên: 05/03/2014, 21:20
Lab Exercises in Organismal and Molecular Microbiology_1 pot
... handling a specimen, and before you touch other objects such as drawer handles, door knobs, refrigerator handles, pens/pencils, and paper. 4. Wash hands thoroughly with soap and water after removing ... Function, and Use of the Microscope E XERCISE 1 3 Alexander−Strete−Niles: Lab Exercises in Organismal and Molecular Microbiology I. Survey of Microscopic Organisms 1. Structure, Function, and Use ... Organismal and Molecular Microbiology I. Survey of Microscopic Organisms 5. Microbial Eucaryotes: Protozoans and Algae © The McGraw−Hill Companies, 2003 Microbial Eucaryotes: Protozoans and Algae...
Ngày tải lên: 05/03/2014, 21:20
Báo cáo khoa học: Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus doc
... composition of its secre- tion apparatus and the molecular details of its secretion mechanisms. This review describes the molecular properties of the Cag-T4SS and compares these with prototypical ... lack the cagPAI and are less virulent. The Cag secretion system is responsible for the induction of a pronounced pro-inflammatory response in vitro and in vivo, and the translocation and subse- quent ... cagPAI and the properties of both conserved and unique components of the Cag-T4SS, together with potential implications for the current understanding of its mode of action. The cagPAI and the...
Ngày tải lên: 06/03/2014, 00:21
Báo cáo khóa học: Biochemical and molecular characterization of a laccase from the edible straw mushroom, Volvariella volvacea docx
... Corresponding pH optima and specific activities for syringaldazine and 2,6-DMP were pH 5.6 and 3.4 UÆmg protein )1 and pH 4.6 and 2.8 UÆmg protein )1 , respectively. In standard assay mixtures, ... growth. In order to better under- stand these effects at the molecular level, we have now purified and characterized one of these laccases, lac1, and cloned and sequenced the cDNA encoding the ... sequences of lac1 and other fungal laccases. *, Amino acid conserved among all of the sequences. Ten His residues and one Cys residue represent the amino acids that serve as Cu 2+ ligands and are shown...
Ngày tải lên: 07/03/2014, 15:20