association of chlamydia pneumoniae with atherosclerosis the evidence

... and development of secondary complications of atherosclerosis Conflict of Interest The authors have declared that no conflict of interest exists References Shor A Chlamydia atherosclerosis lesion, ... endothelium (20) In the present paper we report, that viable elementary bodies of C pneumoniae with typical electron microscopic structure can be isolated from the serum samples of the patients with ... specificity of the primers and probe Real-time PCR was performed with the iCycler IQ ystem (Biorad, USA) µl of extracted DNA was analyzed with the PCR mixture in a total volume of 25 µl The PCR 184...

Ngày tải lên: 26/10/2012, 08:57

... demonstrated the retrograde advance of viruses towards the cell Fig Viral retrograde transport model Both the entry of the viral particle through the endosome pathway (A, C) and the direct fusion of the ... polypeptide stretch The P phosphoprotein of rhabdovirus is a cofactor of the RNA polymerase complex and, in fact, facilitates the binding of the polymerase to the N-RNA complex [67] Using the SAD-D29 ... the fusion of the viral membrane with the plasma membrane of the cell During passage through the cytosol, the viral RNA genome is reverse transcribed into DNA within a structure named the reverse...

Ngày tải lên: 14/03/2014, 22:20

... Possible associations of AD with HLA-B & C alleles Tables and show the overall results for the 26 studied alleles Apart from the associations with HLA-B7 and HLA-Cw*0702 (see below), there was one other ... were found for the HLA-B7/HLACw*0702 haplotype (data not shown) In view of the consistency between the results of the two studies, we pooled the two datasets for further analysis of HLA-B7 and ... Population-specific risk Since the association with HLA-B7 was not replicated in the two other cohorts in our previous study [9], one mainly from Cambridge and the other from Montreal, the association reported...

Ngày tải lên: 19/06/2014, 22:20

... significant at the 5% level In factorial regression, there also was a correlation of the SE with the Ratingen score (P = 0.044) The presence or absence of the SE explained 29% of the variance of the Ratingen ... than 15 years of RA had a median Ratingen score of 38 Calculation of ORs confirmed the association of the SE with a Ratingen score above this median Of interest, the presence of the homozygous ... of the inheritable factors of RA has largely focused on components of the immune system, such as the SE and the cytokine network [1,2,30] In the cohort investigated here, the association of the...

Ngày tải lên: 09/08/2014, 01:23

... risk of urinary tract cancer with fish consumption, for bladder cancer accounts for the overwhelming majority of tumors, and the renal pelvis and ureter are covered by the same urothelium The ... study: the name of the first author, year of publication, the country in which the study was conducted, study design, study period, sample size, exposure of fish consumption, risk estimates with ... fish On the other hand, fish is regarded as a terrific source of polyunsaturated fatty acids This present study is the first meta-analysis summarizing the evidence to date regarding the association...

Ngày tải lên: 09/08/2014, 02:21

... eijk is the trait measured on the individual bull, is the overall mean for the trait, is the effect of the i-th breed (i = 1, 2, 3, 4), is the effect of the j-th SNP genotype within the i-th ... in exon All of these SNPs except for one located 73 bp from the start of exon 2, and another located 95 bp from the start of exon 3, were at silent codon positions and did not affect the encoded ... alter the functioning of the leptin hormone The SNP in exon could be distinguished by digestion with the restriction enzyme Kpn2I following amplication with a purposeful mismatch primer The C...

Ngày tải lên: 09/08/2014, 18:21

... consistent with the TSS are present in all of these genes For example, the heat shock transcriptional regulator HrcA is encoded as the first gene of the dnaK operon and starts bp downstream of the annotated ... upstream of the gene These are Chlamydia trachomatis tuf [27], the rRNA gene [28], and ompA [29] In Cpn, however, the tuf gene is co-transcribed as part of an operon and has no TSS upstream of the ... The ompA gene encodes for the major outer membrane protein of Chlamydia which constitutes more than 60% of the total outer membrane protein content [32] With a total of 3,749 reads ompA was the...

Ngày tải lên: 09/08/2014, 23:20

... proportion of women than the other treatment groups in the training subset In the test subset, mean baseline marker levels were similar among the treatment groups, with the exception of levels of myeloperoxidase, ... significant associations between changes in measures of patient reported outcomes (SF-36 and FACIT-F) and the changed levels of some of the markers in patients treated with golimumab The results ... Pavkova-Goldbergova M, Gatterova J, Vasku A, Soucek M: Association of the 5A/6A promoter polymorphism of the MMP-3 gene with the radiographic progression of rheumatoid arthritis Ann N Y Acad Sci 2007,...

Ngày tải lên: 12/08/2014, 15:22

... feather pattern The only phenotypic difference observed among them is the undercolour, the fluff of the feathers next to the skin; it is white or cream for the ewh and ey males and grey for the ... The clear association between the mainly black feather colour of chickens possessing E and ER and the presence of constitutively active MC1 receptor is in line with the previous observation of ... for the cell number The experiments were repeated three times and qualitatively the results were the same each time The activation level did, however, not reach the maximum level of the other...

Ngày tải lên: 21/02/2014, 00:20

... components of HRQoL [13] There is still limited evidence on relationships of objectively measured fitness and individual domains of HRQoL Therefore, the aim of the present study was to investigate the ... Thus, the final study group consisted of 727 men with mean (SD) age of 25 (5) years The participants signed a written consent form indicating that they were aware of the risks and benefits of the ... benefits of the study The study was approved by the ethical committees of the University of Jyväskylä and the Central Finland Health Care District, as well as the Headquarters of the Finnish Defence...

Ngày tải lên: 18/06/2014, 19:20

... the submucosal layer of the stomach, through the serosal layer and the muscle layer, the injection site was pressed for to keep the injected tumor cells in place, and the abdomen was closed with ... well as 12 h of light and dark cycle per day The animal study protocol was approved by the Animal Welfare Committee of the Center Construction of rabbit model of VX2 gastric carcinoma with PC Rabbit ... reports in the literature on the efficacy of CRS + HIPEC in experimental animal models of PC Klaver et al [34] used the rat colonic carcinoma PC model to test whether the addition of HIPEC to...

Ngày tải lên: 18/06/2014, 19:20

... the submucosal layer of the stomach, through the serosal layer and the muscle layer, the injection site was pressed for to keep the injected tumor cells in place, and the abdomen was closed with ... well as 12 h of light and dark cycle per day The animal study protocol was approved by the Animal Welfare Committee of the Center Construction of rabbit model of VX2 gastric carcinoma with PC Rabbit ... reports in the literature on the efficacy of CRS + HIPEC in experimental animal models of PC Klaver et al [34] used the rat colonic carcinoma PC model to test whether the addition of HIPEC to...

Ngày tải lên: 20/06/2014, 03:20

... association of hypoglycemic symptoms with measures of QOL was examined using the t test The F test was used to test the null hypothesis of no association of hypoglycemic symptom severity with QOL The ... 0.0106 Data are mean ± SD unless otherwise specified * Based on the t test of the null of no differences in the mean quality of life scores between patients with and without hypoglycemic symptoms ... asthenia, and headache The association of hypoglycemic symptoms and their severity with patients’ perception of health needs to be addressed in conjunction with both diabetes severity and other...

Ngày tải lên: 20/06/2014, 16:20

... generated by the simulation must be kept, together with the MSC traces of the scenarios that satisfy the observers If all the reachable states of the SDL model have been explored, the simulation ... indication on the other side of the connection; then, if the layer above accepts, it transmits a response, translated into a confirm on the side originator of the request 3.2 SPECIFICATION OF THE V.76 ... information field of this frame to the SU using the L-DATA indication primitive 3.2.5 Release of a DLC The SU requests release of a DLC4 by use of the L-RELEASE request primitive, then the DLC entity...

Ngày tải lên: 27/06/2014, 00:20

... Germany) Since the colour of test drugs like doxorubicin might interfere with the absorption of the MTS formazan, the in vitro tests of anticancer drugs was performed with the MTT test, while the cytotoxicity ... despite of all further efforts within recent years the prognosis of patients with advanced and/or disseminated disease is still poor, demonstrating the need of new therapeutic approaches for these ... Germany) In the first step of the TRAP assay, telomerase of cell lysates added hexamer repeats of telomeric sequence (TTAGGG) onto the 3’-end of an included oligonucleotide Subsequently the synthesized...

Ngày tải lên: 09/08/2014, 09:20

... ability to change) The research team then met and shared their individual ratings Discrepancies were resolved by discussing the practice from the diverse points of view of the team members When ... post-hoc analysis assessed the association of an interaction term (the product of both ratings) with the outcome at both time points A twotailed p value < 0.05 served as the threshold for statistical ... motivations and abilities within a practice for the sake of greater implementation effectiveness, especially because the contribution of these features relative to that of other factors included...

Ngày tải lên: 11/08/2014, 05:21

... ability to change) The research team then met and shared their individual ratings Discrepancies were resolved by discussing the practice from the diverse points of view of the team members When ... post-hoc analysis assessed the association of an interaction term (the product of both ratings) with the outcome at both time points A twotailed p value < 0.05 served as the threshold for statistical ... motivations and abilities within a practice for the sake of greater implementation effectiveness, especially because the contribution of these features relative to that of other factors included...

Ngày tải lên: 11/08/2014, 16:21

... of ischaemia during the exercise test The patient was a non-smoker and did not drink coffee or use alcohol Thus, there was no obvious cause for the PVCs in this case A less well-known cause of ... copy of the written consent is available for review by the Editor-in-Chief of this journal Acknowledgements The author would like to thank Dr Derek Filbey for his linguistic revision of the manuscript ... electrocardiogram (ECG) the following morning, which showed PVCs in bigeminy The patient had also sinus tachycardia with a heart rate of about 110 beats per minute The patient was admitted to the cardiac...

Ngày tải lên: 11/08/2014, 21:22

... using the next algorithm: first the intensity of the positive area (cells) was appointed in each biopsy by the observer, followed by the intensity of the total area of the biopsy, based on the ... and revised the manuscript NtH contributed to the conception and design of the study, the data collection and the interpretation of the data and revised the manuscript BR carried out the sputum ... and revised the manuscript DP contributed to the conception and design of the study, the data collection and the interpretation of the data and revised the manuscript WT contributed to the conception...

Ngày tải lên: 12/08/2014, 18:21

... [16] Furthermore, deposition of lipofuscin, a by-product of lipid peroxidation, characterizes TPNinduced cholestasis in preterm infants [17] The purpose of these studies was to determine whether ... (TBARS) The most abundant of these substances is MDA, an aldehydic lipid peroxidation product formed by the action of ROIs on lipid membranes The identification of ROIs as potential markers of liver ... consent was obtained from parents for the acquisition of samples, and these studies were approved by the Committee for the Protection of Human Subjects in Research of St Peter’s University Hospital...

Ngày tải lên: 12/08/2014, 19:21