association of chlamydia pneumoniae with atherosclerosis potential pathogenetic mechanisms

... C .pneumoniae- specific IgA and IgG antibodies were evaluated by using Chlamydia pneumoniae- IgG-ELISA medac plus and Chlamydia pneumoniae- IgA-ELISA plus commercial kits with highly purified C .pneumoniae ... immunofluroscence analysis with chlamydial LPS-specific antibody A total of specimens from ACS patients were positive for chlamydial growth with LPS-specific antibody revealing the presence of ... finding of C pneumoniae in serum of ACS patients does not establish causality for the pathogen in development of atherosclerosis However, increased positivity rate for presence of C pneumoniae...

Ngày tải lên: 26/10/2012, 08:57

... experimental points, independent of concentration of a-MSH, as compared with the nontransfected cells The cells transfected with hMC4-E100K, in contrast with the chicken receptors with Lys in position 92, ... concentrations of a-MSH, the cAMP levels were lower than that observed for the cells transfected with eb, E and ER All experiments were performed with a similar number of cells; the amount of protein ... results cannot completely explain the association of cMC1 variants with the corresponding phenotypes It is possible that the expression levels of cMC1 receptor vary with different alleles, which results...

Ngày tải lên: 21/02/2014, 00:20

... disassembly (b) This is in agreement with the modeled solution structure of the complex of DYNLL1 with p54 of ASFV [26] (B) Three hypotheses for the association of viral proteins to the dynein molecular ... phosphoprotein of rhabdovirus is a cofactor of the RNA polymerase complex and, in fact, facilitates the binding of the polymerase to the N-RNA complex [67] Using the SAD-D29 low-virulent strain of RV, ... KSTQT and KSIQI in the case of the P protein of rabies and Mokola viruses respectively [70,71] and SQTQT in the case of protein VP35 of ebolavirus [103] The presence of these sequences that closely...

Ngày tải lên: 14/03/2014, 22:20

... activity with feeling out of breath or sweating twice a week, (5) physical activity with feeling out of breath or sweating three times a week, and (6) physical activity with feeling out of breath ... single question with six categories: (1) no physical activity at all, (2) some physical activity without feeling out of breath or sweating, (3) physical activity with feeling out of breath or sweating ... means with standard deviation (SD) or 95% confidence level (CI) The normality of variables was evaluated by Kolmogorov-Smirnoff test and by means of histograms The statistical significance of characteristics...

Ngày tải lên: 18/06/2014, 19:20

... an association of homozygotes, not of heterozygotes of HLA-A2 with earlier onset of AD; however, HLA-A2 is on a different haplotype from HLAB7/HLA-Cw*0702/HLA-A3 Alternatively, could the lack of ... study [9], with 55 cases of AD and 73 controls from the Oxford Project to Investigate Memory and Ageing (OPTIMA), suggested an association with AD of two alleles in linkage disequilibrium with each ... use of non-steroidal anti-inflammatory drugs is associated with reduced risk of AD [4-6] The region has proved a challenge for the study of disease associations, because it is highly variable, with...

Ngày tải lên: 19/06/2014, 22:20

... demonstrate significant associations, the rest of the countries with no significant associations were represented with a small number of observations This may be one of many reasons for the observed ... quality of life in diabetes: The associations of complications with EQ-5 D scores Heath and Quality of Life Outcomes 2010, 8:18 American Diabetes Association: Diagnosis and classification of diabetes ... because of the use of a non-probability-based sample of physicians and patients The study eligibility requirement of at least one HbA1c measurement within 12 months may have selected for patients with...

Ngày tải lên: 20/06/2014, 16:20

... Expression of CD45 is in relation to CD14 in BMSCs PBMMP has Increased Proliferation, Collagen Secretion and Similar Multi-differentiation Potential compared with BMSCs In culture of BMSCs mixed with ... of a small population of circulating MSCs But the isolation of these cells is obviously difficult and these cells are subject to variation depending on the methods for isolation and sorting of ... PBMSCs’ differentiation (unpublished data) In the absence of external influence, a population of CD14- mesenchymal cells with hematopoietic potential was harvested However, whether this population...

Ngày tải lên: 08/08/2014, 18:20

... Journal of Surgical Oncology 2011, 9:107 http://www.wjso.com/content/9/1/107 Page of Figure Process of study selection for fish consumption and risk of bladder cancer included more than 200 cases of ... that supplementing the diet of tumor-bearing mice or rats with purified n-3 fatty acids has slowed the growth of various types of cancers [28-30] In addition, intake of oils containing EPA or DHA ... association of fish consumption with bladder cancer risk: A meta-analysis World Journal of Surgical Oncology 2011 9:107 Submit your next manuscript to BioMed Central and take full advantage of: ...

Ngày tải lên: 09/08/2014, 02:21

... antagonistic effects of telomerase inhibition combined with chemotherapy and suggests positive effects of combinations with certain anticancer drugs Further experiments should clarify the role of telomerase ... at a wavelength of 490 nm using a microplate reader (BioRad Laboratories, München, Germany) Since the colour of test drugs like doxorubicin might interfere with the absorption of the MTS formazan, ... International, Germany) In the first step of the TRAP assay, telomerase of cell lysates added hexamer repeats of telomeric sequence (TTAGGG) onto the 3’-end of an included oligonucleotide Subsequently...

Ngày tải lên: 09/08/2014, 09:20

... Furthermore an association of CPn0332 with ribosomes can be excluded, since the RNA does not co-sediment with ribosomal RNAs (Additional file 1, Figure S6) Although an association of CPn0332 RNA with σ28 ... was freed of residual genomic DNA by treatment with 1U DNase I per µg of RNA for 30 minutes at 37° For depletion of processed transcripts, equal amounts of Chlamydia RNA C were incubated with TEX ... current knowledge of Chlamydia pneumoniae and atherosclerosis J Infect Dis 2000, 181 Suppl 3:S402-410 Moulder JW: The relation of basic biology to pathogenic potential in the genus Chlamydia Infection...

Ngày tải lên: 09/08/2014, 23:20

... through review of a cross-sectional sample of medical records for patients seen on a randomly selected day within two weeks of study baseline (month 0), month 6, month 12 (end of the intervention), ... to the components of the combined score, a supplemental analysis demonstrated a strong association with instrumental change capacity (3.2%, p = 0.002); a weaker association with motivation to ... important that studies examining the association of practice capacity for change with implementation use measures that represent both components and assess their potential interaction Despite considerable...

Ngày tải lên: 11/08/2014, 05:21

... through review of a cross-sectional sample of medical records for patients seen on a randomly selected day within two weeks of study baseline (month 0), month 6, month 12 (end of the intervention), ... to the components of the combined score, a supplemental analysis demonstrated a strong association with instrumental change capacity (3.2%, p = 0.002); a weaker association with motivation to ... important that studies examining the association of practice capacity for change with implementation use measures that represent both components and assess their potential interaction Despite considerable...

Ngày tải lên: 11/08/2014, 16:21

... signs of false tendons No ischaemia was seen on ECG and there were no signs of infarction The frequency of PVCs began to decrease about hours after admission Blood tests showed no indications of ... revision of the manuscript Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of ... of ischaemia during the exercise test The patient was a non-smoker and did not drink coffee or use alcohol Thus, there was no obvious cause for the PVCs in this case A less well-known cause of...

Ngày tải lên: 11/08/2014, 21:22

... of predictive values of CRP versus combination of markers With a logistic regression analysis, the best combination of markers (based on change from baseline to week 4) that were associated with ... predictors of ACR 20 response at week 14, followed by baseline levels of rheumatoid factor Associations between biomarker levels and health-related quality -of- life outcomes We examined the associations ... and patient reported measures of health-related quality of life (SF-36) and fatigue (FACIT-F) We previously showed that RA patients treated with golimumab with or without MTX showed significantly...

Ngày tải lên: 12/08/2014, 15:22

... smokers with severe COPD [22,41] It may thus well be that differences between smokers with and without COPD become only apparent in case of severe COPD Unfortunately the number of patients with ... negatively with the number of pack-years smoking (r = -0.51, p = 0.03) in COPD, but not significantly with the number of cigarettes smoked per day FEV1 post BD correlated negatively with IL-8 ... cell tryptase Correlations of current smoking with airway inflammation The number of cigarettes smoked per day correlated negatively with neutrophils and positively with macrophages in sputum,...

Ngày tải lên: 12/08/2014, 18:21

... most abundant of these substances is MDA, an aldehydic lipid peroxidation product formed by the action of ROIs on lipid membranes The identification of ROIs as potential markers of liver injury ... antioxidants [8–10] Consistent with these findings, several forms of liver disease in humans have been shown to be associated with oxidative tissue injury Specifically, products of lipid peroxidation ... products [16] Furthermore, deposition of lipofuscin, a by-product of lipid peroxidation, characterizes TPNinduced cholestasis in preterm infants [17] The purpose of these studies was to determine...

Ngày tải lên: 12/08/2014, 19:21

... association with delayed mortality, independent of age and number of SIRS criteria In agreement with this, a significant association with lower number of SIRS criteria and a tendency to a higher ... towards increased levels was observed in patients with sepsis, irrespective of severity, as compared with patients with SIRS without infection While no association was found according to the 1377delA ... significance of these findings and to explain their molecular background Key messages In accordance with the high degree of HMGB1 structural conservation and with the location of the majority of previously...

Ngày tải lên: 13/08/2014, 11:22

... 610 T allele associated with ↑ likelihood of chronic Chlamydia infection [118] Acute pancreatitis 117 cases, 263 controls No association with sCD14 or mCD14 No association with disease severity ... for Chlamydia pneumoniae infection [114] Very low birth weight infants 356 No association with development of blood-culture proven sepsis [115] Tuberculosis patients 267 cases, 112 controls No association ... No association with severity of pancreatitis [48] ICU patients with SIRS 252 patients TT ↑ Gram negative cultures [39] Critically ill Japanese patients 197 cases, 214 controls No association with...

Ngày tải lên: 13/08/2014, 11:23

... 2.3 Chlamydia Pneumoniae 18 2.3.1 Chlamydia Pneumoniae AR39 19 2.3.2 Life Cycle of Chlamydia Pneumoniae 21 2.3.3 Medical Significance of Chlamydia Pneumoniae 24 2.3.4 Difficulties of Chlamydia Pneumoniae ... overview diagram of the five models of study of the association of Chlamydia pneumoniae and Atherosclerosis The third model consists of human macrophage U937 cell line and Chlamydia pneumoniae; the ... of study of 10 the association of Chlamydia pneumoniae and Atherosclerosis Figure Outline of the experimental strategy 14 Figure A schematic representation of the Chlamydia pneumoniae 20 AR39...

Ngày tải lên: 03/10/2015, 11:36

... are inversely related to BMI Thus potential associations of PPARδ with HDL-C levels could be masked by the profound effect of overweight on HDL-C in the patients with high BMI To establish whether ... Marian AJ Effects of PPARα, γ and δ haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis ... a significantly higher incidence of coronary heart disease for carriers of at least one C allele (p=0.033) (table 4) Among those with a BMI below 24.6 carriers of the rare C allele had a significantly...

Ngày tải lên: 31/10/2012, 17:03