association between oxidative stress and periodontal diseases in animal model studies

... significantly reduced (p ＜ 0.05) in all groups compared to the control group Similar finding have been reported in other study during oxidative stress [24] No significant changes in GST activity was seen ... 181-193 Taplin D, Meinking TL Pyrethrins and pyrethroids in dermatology Arch Dermatol 1990, 126, 213-221 Trojanowski JQ Rotenone neurotoxicity: a new window on environmental causes of Parkinson’s ... resistant strain of insect [38] GST levels were also increased significantly after 30 days of exposure to protect RBCs from oxidative damage Further significant decreases in GSH levels in our study...

Ngày tải lên: 07/08/2014, 23:22

... risk factors, including body mass index (BMI) and creatinine levels, but also for the presence of self-reported CVD Mixed model linear regression was used to examine longitudinal associations ... NT-proBNP in the linear regression analyses (Table 2) This significant association was also maintained in the multivariate linear regression analyses, which included the interaction between age ... examined the association between markers of inflammation in RA and BNP/NTproBNP It could be argued that the association between CRP and NT-proBNP identified in our study is a consequence of the inflammatory...

Ngày tải lên: 09/08/2014, 10:23

... alveolar septum In ALI conditions, a minor increase in hyperinflated areas and a steady amount of normally aerated areas were observed Bearing this in mind, the increase in Ers in animals with ALI ... depicted in Figures to Note that PEEPErs resulted in the best compromise between normally, hyperinflated and non-aerated areas in all studied animals A predominance of hyperinflated areas in nondependent ... system mechanics may help in minimising ventilatorinduced lung injury in ARDS patients Eur Respir J 2003, 22:15S-21S Hickling KG: Best compliance during a decremental, but not incremental, positive...

Ngày tải lên: 13/08/2014, 08:20

... trait locus (QTL) study in mice Using an F2 population generated from an original cross of two inbred strains differing dramatically in their physical activity levels, these investigators uncovered ... endocrine, etc.) may be involved However, some recent studies by Good and colleagues [37-39] provide clear evidence of one example in which the nervous and endocrine systems are involved in the linkage ... dominance index values, WT, and the interactions of body weight with the index values on distance, duration, and speed Essentially this is an analysis of covariance model where the interest is in...

Ngày tải lên: 14/08/2014, 13:21

... organism to particle-induced oxidative stress The observed increase of reducing species in urine would mirror an increased level in blood originating from a response to oxidative stress in the body monitored ... associated to an increase in urinary 8OHdG levels during two consecutive days in non-smoking male bus mechanics This increase in oxidative stress markers was associated with increased urinary level ... oxidative stress [7] was verified by testing the correlation between levels of 8OHdG, reflecting oxidative stress, and the reducing capacity (corresponding to a defense against oxidative stress) in...

Ngày tải lên: 20/06/2014, 00:20

... complex studies, involving many model systems and investigating phenomena from different points of view 14 Oxidative Stress and Diseases Fig Ways leading to oxidative stress Reactive oxygen ... positively charged amino acid residues, lysine and arginine, from N-terminus and arginine and histidine from C-terminus (Bravard et al 2009) Such amino acid cluster is thought to increase possibility ... oxidative stress in goldfish brain, Brain Research, Vol 1052, No 2, pp 180-186 8 Oxidative Stress and Diseases Burcham, P.C & Kuhan, Y.T (1996) Introduction of carbonyl groups into proteins by...

Ngày tải lên: 12/02/2014, 16:20

... long chain fatty acids (Elovl3), type iodothyronine deiondinase (Dio2), homeobox C9 (Hoxc9), insulin-like growth factor binding protein (Igfbp3), dermatopontin (Dpt), and b-actin are showed in Table ... reduced in both eWAT and iBAT in response to PM2.5 exposure Recent studies have implicated PM2.5 in increased adipose inflammation and insulin resistance [11,12], and epidemiological studies indicate ... deviation inflammatory response and IR development, were examined in mice As shown in Figure 3, PM 2.5 exposure induced a marked increase in macrophage (F4/80+ cells) infiltration in eWAT Next,...

Ngày tải lên: 06/03/2014, 19:20

... was mainly localized in microsomal compartments (ROS) [9] The overexpression of CYP2E1 both in vivo and in vitro is associated with several cellular markers of oxidative stress, including products ... longitudinal sections are shown in (A) (magnification ·20; scale bars = mm) The hemotoxylin and eosin-stained sections of the left ventricle are shown in (B) and Masson’s trichrome stained sections ... radical formation in diabetic rats induced by streptozotocin Life Sci 56, 1789–1798 Hodges NJ, Green RM, Chipman JK & Graham M (2007) Induction of DNA strand breaks and oxidative stress in HeLa cells...

Ngày tải lên: 22/03/2014, 16:20

... significantly inhibited by mm benzamide (Fig 4A,B), confirming PARP activation in D discoideum under oxidative stress PARP inhibition during oxidative stress- induced growth changes in D discoideum ... with larger fruits PARP involvement during oxidative stress- induced developmental changes in D discoideum To determine the role of PARP in oxidative stressinduced developmental changes, D discoideum ... activity observed during oxidative stress (Fig 4A,B) Under oxidative stress, partial inhibition of PARP activity led to altered growth, suggesting that oxidative stress could be leading to cell cycle...

Ngày tải lên: 23/03/2014, 07:20

... negative to propidium iodide staining (data not shown), indicating that the plasma membrane is maintained intact, allowing us to exclude primary necrosis as the principal cell death modality Moreover, ... ANT1-silencing effect on cell viability is independent of its primary role in ATP ⁄ ADP exchange Our data allow us to suggest a model in which ANT1 depletion might trigger, in ADF cells, an increase in ... is more abundant than ANT1 in ADF cells, although we observed that silencing of ANT1, but not ANT2, strongly reduced ADF viability by inducing an increase in oxidative stress that leads to cell...

Ngày tải lên: 29/03/2014, 09:20

... largely in the gastrodermal tissue harboring the zooxanthellae (Fig 6B) Effect of heat stress on antioxidant defenses and bleaching in animal tissue of A viridis The occurrence of oxidative stress in ... mechanisms point to the involvement of oxidative stress in the early stages of symbiosis breakdown In fact, several authors have suggested the involvement of ROS production in the zooxanthella photoinhibition ... bleaching of the experimental animals occurred as the heat stress incubation progressed This result supports the induction of a bleaching event as a consequence of an oxidative stress period In...

Ngày tải lên: 30/03/2014, 10:20

... Coordinator The remaining 34 are non-focus countries One hundred and forty-nine health indicators were found in the initial database search, most of which were missing data points Of the indicators ... There has been a welldocumented increase in individuals receiving HIV care in locations receiving PEPFAR funding [8], and several studies have suggested local decreases in mortality where HIV services ... by boosting infrastructure, training and supplies, and increasing public confidence in the health care system of many developing countries [4,24] The WHO data we have analyzed, which incorporates...

Ngày tải lên: 20/06/2014, 08:20

... low stress is indicated by numbers pointing to '0' and high psychological stress is characterized by numbers pointing to '20' The sum score (scale from 0–20) was used as a continuous variable in ... is indicated by numbers pointing to '0' and high quality is characterized by numbers pointing to '100' A certified translation of the questionnaire from English into Arabic language including ... sample Another main finding of this study is that psychological stress was related to all domains of quality of life among hypertensive patients This result confirms findings in a study from Ames...

Ngày tải lên: 08/08/2014, 21:20

... improves glucocorticoid induced insulin-like growth factor 1(IGF1) resistence without influencing myoglobin and IGF1 binding proteins and Ann Rhuem Dis 2006, 65:301-305 Fraser R, Ingram MC, Anderson ... was reflected in our study, in which an increase in HDL levels was seen in patients receiving longterm GCs (P = 0.011) The observed rise in HDL levels may also be explained by the indirect effects ... smaller bank of conflicting data demonstrating that GC use in RA paradoxically restores glucose handling to normal whilst also inducing hyperinsulinism [68] In the present RA population, it is possible...

Ngày tải lên: 09/08/2014, 01:22

... MS to obtain peptide mass information Spectra obtained were compared with those registered in protein databases (SWISS-PROT and NCBInr) R1397 NPM-binding activity in other mouse strains We then ... staining on Hep-2 cells by indirect immunofluorescence analysis (Fig 2e) The nucleolar staining disappeared when sera were preincubated with recombinant NPM (Fig 2f) in lupus mice Correlation between ... activity of 4B7 mAb Binding of rhNPM to cardiolipin and effects of nucleophosmin on cardiolipin-binding activity of 4B7 mAb (a) Cardiolipin was coated on plastic plates and incubated with various...

Ngày tải lên: 09/08/2014, 07:20

... equally in the anti-TNF group There is, however, a possible explanation based on the differential dropout between the studies following entry into the trials Typically, all patients entered into ... hospitalization or intravenous antibiotic use, and the threshold for these interventions might differ both between trials and between treatment arms within a trial; if an individual has a good ... accruing from large national registers of unselected anti-TNF treated patients with the appropriate comparison groups Competing interests WD is the Clinical Research Fellow and AS is joint principle...

Ngày tải lên: 09/08/2014, 08:22

... Recently, there has been increasing interest in the peak external knee adduction moment in epidemiological studies examining knee joint morphology and the genesis of knee OA and pain [8-11] The peak ... was included within the models and did not alter the results, thus implying that the association between adduction moment, foot rotation, and meniscal tear are independent of knee injury Finally, ... competing interests Authors' contributions FC and AW were involved in the design and implementation of the study, including data collection and measurement, and were involved in the analysis and interpretation...

Ngày tải lên: 09/08/2014, 10:23

... improves glucocorticoid induced insulin-like growth factor 1(IGF1) resistence without influencing myoglobin and IGF1 binding proteins and Ann Rhuem Dis 2006, 65:301-305 Fraser R, Ingram MC, Anderson ... was reflected in our study, in which an increase in HDL levels was seen in patients receiving longterm GCs (P = 0.011) The observed rise in HDL levels may also be explained by the indirect effects ... smaller bank of conflicting data demonstrating that GC use in RA paradoxically restores glucose handling to normal whilst also inducing hyperinsulinism [68] In the present RA population, it is possible...

Ngày tải lên: 09/08/2014, 13:22

... protein (CRP), and routine laboratory testing were within normal ranges, except for a mild increase in low-density lipoprotein (LDL) cholesterol that was attributed to isotretinoin use Urine analysis ... reports indicate a possible protective effect of isotretinoin in thromboembolic disorders Some of the underlying mechanisms may be the decrease in lipoprotein (a) which has been implicated in coronary ... examinations and was involved in writing and reviewing the manuscript MK carried out part of the general medical work-up and the genetics investigation IM performed the general clinical investigation...

Ngày tải lên: 11/08/2014, 20:20

... variability of inflammatory and immune responses in CIV-infected hosts In similar study of viral shedding in human after infection of pandemic H1N1, viral load was maintained at a high level during the ... that commingle with a canine influenza infected dog shed different levels of virus in their nasal excretions The correlation between the viral shedding and clinical signs of canine influenza ... elucidating its structure and genome, the immune responses it elicits, testing protective vaccines, and studying influenza epidemiology However, information regarding the kinetics of influenza...

Ngày tải lên: 11/08/2014, 21:21