... corresponding to tryptophan emission (j) or Oregon green emission (h) is plotted vs pH (B) The maximum wavelength of tryptophan fluorescence emission is plotted vs pH Kd is less for the last condition ... used to monitor interaction of gelsolin domains, peptides to gelsolin domains and to actin as described previously [22,33] Polyclonal antibodies to domains G4–6 were elicited in rabbits as described ... [5,22] We propose that low pH sets off a similar but distinct set of ionpair exchanges, presumably initiated at histidine residues, that also disrupts interdomain bonds but not those formed through...
Ngày tải lên: 23/03/2014, 21:20
... nonrecombining genomes is degraded or less functional than genes from recombining chromosomes The absence of differential selection between dogrose genomes is surprising because it is assumed that sect Caninae ... selective regimes than alleles with one copy we estimated the ratio (ω) of the rate of nonsynonymous substitutions at non-synonymous sites (dN) to synonymous substitutions at synonymous sites ... transcription factor expressed in floral organs whereas the two other loci cGAPDH and nrITS are expressed in every tissue, but recent studies demonstrate that gene classification is not a strong...
Ngày tải lên: 11/08/2014, 11:21
Báo cáo khoa học: "To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection" potx
... through PAR1-dependent sphingosine 1phosphate receptor-1 crossactivation Blood 2005, 105: 3178-3184 Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG: Activated ... Rosen ED, Fukudome K, Zlokovic BV: Activated protein C blocks p53mediated apoptosis in ischemic human brain endothelium and is neuroprotective Nat Med 2003, 9:338-342 Page of (page number not ... Critical Care Vol 11 No Li Competing interests The authors declare that they have no competing interests References Looney MR, Matthay MA: Bench -to- bedside review: The role of activated protein...
Ngày tải lên: 13/08/2014, 03:20
The school production – to be or not to be
... this thesis is a refurbished Shakespearean script, A Midsummer Night s Dream The term refurbished is taken from the Shakespearean script Macbeth where the term ‘furbished’ means gleaming, shining ... potentially repress student potential in the process? While this is not what the thesis seeks to answer, in exploring the authentic model of school production the thesis poses this question time and ... connectedness Not only did teachers and principals resist the authentic model of production, students resisted This student resistance became of great significance for this research Students felt...
Ngày tải lên: 28/11/2015, 14:03
SECTION 10: FOUNDATIONS TABLE OF CONTENTS [TO BE FURNISHED WHEN SECTION IS FINALIZED]
... soil, emphasis is placed on visual assessment of the rock and the rock mass Other methods for assessing rock mass strength, including in-situ tests or other visual systems that have proven to yield ... Axial compression resistance for single drilled shafts Shaft group compression resistance Uplift resistance for single shafts Uplift resistance for shaft groups Single shaft and shaft group ... its tip Drilled shafts are also commonly referred to as caissons, drilled caissons, bored piles, or drilled piers Effective Stress — The net stress across points of contact of soil particles,...
Ngày tải lên: 06/09/2012, 15:57
SECTION 10 FOUNDATIONS TABLE OF CONTENTS [TO BE FURNISHED WHEN SECTION IS FINALIZED] - DRILLED SHAFTS
... curves in side resistance and in end bearing for shafts in cohesive soils Figures and are similar curves for shafts in cohesionless soils These curves should be used for estimating shortterm settlements ... loaddisplacement curve, shafts in cohesionless soils often have no well-defined failure at any displacement The resistance of drilled shafts in cohesionless soils continues to increase as the settlement ... tip resistance (KSF) The nominal axial compression resistance of a shaft is derived from the tip resistance and/or shaft side resistance, i.e., skin friction Both the tip and shaft resistances develop...
Ngày tải lên: 29/09/2013, 12:20
SECTION 10 FOUNDATIONS TABLE OF CONTENTS [TO BE FURNISHED WHEN SECTION IS FINALIZED] - DRIVEN PILES
... In-situ tests are widely used in cohesionless soils because obtaining good quality samples of cohesionless soils is very difficult In-situ test parameters may be used to estimate the tip resistance ... used for pile bearing resistance quality control, pile bearing resistance should be determined using the Case Method analysis If the Case method is used to estimate pile bearing resistance where ... experience Note that R n is considered to be nominal 10-91 bearing resistance of the pile needed to resist the applied loads, and is used as the basis for determining the resistance to be achieved during...
Ngày tải lên: 29/09/2013, 12:20
SECTION 10 FOUNDATIONS TABLE OF CONTENTS [TO BE FURNISHED WHEN SECTION IS FINALIZED] - EXTREME LIMIT STATES
... resistance of spread footings on cohesionless soils shall be evaluated using effective stress analyses and drained soil strength parameters The nominal bearing resistance of spread footings on ... 10.6.1.4 BEARING STRESS DISTRIBUTIONS When proportioning footing dimensions to meet settlement and bearing resistance requirements at all applicable limit states, the distribution of bearing stress ... cohesive soils shall be evaluated for total stress analyses and undrained soil strength parameters In cases where the cohesive soils may soften and lose strength with time, the bearing resistance...
Ngày tải lên: 29/09/2013, 12:20
SECTION 10 FOUNDATIONS TABLE OF CONTENTS [TO BE FURNISHED WHEN SECTION IS FINALIZED] - FOUNDATIONS
... soil, emphasis is placed on visual assessment of the rock and the rock mass Other methods for assessing rock mass strength, including in-situ tests or other visual systems that have proven to yield ... Axial compression resistance for single drilled shafts Shaft group compression resistance Uplift resistance for single shafts Uplift resistance for shaft groups Single shaft and shaft group ... shafts, static load test (DIM) (10.5.5.2.4) resistance factor for tip resistance (DIM) (10.8.3.5) resistance factor for shaft side resistance (DIM) (10.8.3.5) resistance factor for sliding resistance...
Ngày tải lên: 29/09/2013, 12:20
Conclusion - what is to be done
... which seem to be related In this sense, globalisation, whilst having a long historical background as old as merchants and religious proselytisers, appears to be a process which deserves to be recognised ... is the sheer number of jurisdictions and normative discourses within and across such territories and spheres The universalist peace which is being pursued is also revolutionary in response to ... (Atlanta: Scholars Press, 1993), p 301 313 Conclusion: what is to be done? break with its Nazi past’.45 This historical style of argument is perhaps pertinent to raise in the face of any exercise of...
Ngày tải lên: 01/11/2013, 08:20
Tài liệu NOT TO BE CITED WITHOUT PRIOR REFERENCE TO THE AUTHOR(S) doc
... creation of inventory records and software, support to OBIS, a general access system to fisheries data and continuing development of a services oriented architecture References List of NAFO Standard ... the rest at addressing standards, and some funding for meetings Types of data included bathymetry, various fisheries data, zooplankton, marine mammals and nutrients Access projects addressed creation ... threat to Canada 's fisheries and aquaculture industry and have been entering Canadian waters for centuries but never as rapidly as today Every decade, some 15 alien species establish themselves in...
Ngày tải lên: 21/02/2014, 12:20
Tài liệu To Hate Like This Is to Be Happy Forever doc
... Republicans, the Yankees versus the Confederates, Capitalism versus Communism All right, okay, the Life Force versus the Death Instinct, Eros versus Thanatos Is that big enough? This is a rivalry of such ... really shouldn’t use that sort of language, the journalist told the beast It s not the sort of language a journalist uses Fuck you, you wimp, the beast responded I can see this is going to be something ... bartender laughs, not because the joke is funny but because his customer is spilling over with joviality To Hate Like This Is to Be Happy Forever 17 and goodwill He slaps hands with the black...
Ngày tải lên: 21/02/2014, 17:20
PROFESSOR TRIM’S QUICK START THE WEIGHT-LOSS PROGRAM for new mothers and mothers-to-be pdf
... strain is not an issue In fact if the stressor is too weak it can even lead to boredom If, on the other hand, the capacity of the person being stressed is less than the severity of the stress being ... bodies, and muscle is active, it helps to increase metabolic rate— provided this is combined with exercise (see Chapter 3) Protein is also generally not turned to fat, because any excess is lost ... be able to guide you on the use of other therapies (such as special diets and possibly even anti-obesity drugs) and may enlist the assistance of a dietitian or obesity specialist It is also important...
Ngày tải lên: 15/03/2014, 04:20
To Cut or Not to Cut? That is the (Central Bank’s) Question In Search of the Neutral Interest Rate in Latin America pdf
... currencies 23 Evidence on these issues is still to be presented But a deeper discussion of the role of MaPPs as complement or substitute to standard interest rate polices deserves better attention ... analysis on MaPP seems to be symmetric, except for its fiscal cost If capital inflows are sterilized (purchasing reserves with domestic paper) the quasi-fiscal cost increases Capital outflows, ... period) All stochastic disturbances are assumed to be zero mean variables with constant variances The transition process for the (state) NRIR is given by a random walk process as described above,...
Ngày tải lên: 15/03/2014, 14:20
Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx
... membranes To complement our MC99-3FLAG based in vitro c-secretase assays, an in vitro assay using COS7SPC99-3FLAG CHAPSO extracts was developed The substrate in this assay is synthesized, processed, ... mechanisms to control the aggregation states of these substrates and supports our original hypothesis that mammalian cellular factors enable endogenous proteins to be presented to the c-secretase ... MC99-3FLAG substrate and phospholipid was added to fractions, activity was not detected Thus, substrate limitation is not the reason that PS1 complexes of this size range were unable to sustain robust...
Ngày tải lên: 16/03/2014, 23:20
REFORMING AMERICA’S HOUSING FINANCE MARKET: A REPORT TO CONGRESS pdf
... a consistent basis since the Depression But in the years leading up to the recent crisis, a robust expansion in credit, fueled by processes and financial instruments designed to shift risk away ... pressure on housing assets Risk throughout the system may also be reduced, as private actors will not be as inclined to take on excessive risk without the assurance of a government guarantee behind ... requirements so that regulators and investors can more easily understand the underlying collateral and risks of securities Strengthen transparency and disclosure in credit ratings agencies’ analysis...
Ngày tải lên: 23/03/2014, 02:20
How Is Deployment to Iraq and Afghanistan Affecting U.S. Service Members and Their Families potx
... greatly increased its use of enlistment and reenlistment bonuses This expansion in reenlistment bonuses was fortuitous in the sense that the bonuses helped to stave off a decrease in reenlistment from ... “deployment” has to with the number of long workdays This is not to discount the possible role of specific dangers such as improvised explosive devices (IEDs), snipers, ambushes, and other hazards But available ... lose income during activation than the survey-based estimates suggest In fact, earnings tend to increase This is because reservists have two sources 30 How Is Deployment to Iraq and Afghanistan...
Ngày tải lên: 23/03/2014, 08:20
Báo cáo khoa học: It’s cheap to be colorful Anthozoans show a slow turnover of GFP-like proteins potx
... symbiont reduces the transfer of photosynthetic products to the host Indeed, we observed a partial loss of zooxanthellae during this time (data not shown) To assess the influence of this stressful ... contrast, control animals, which were exposed to light for the same time interval, displayed constant overall red fluorescence of the tissue Prolonged darkness is stressful for the corals because ... that photoconversion is avoided and photobleaching is minimized In this study, we used this approach to measure the half-lives of greento-red photoconvertible proteins in corals in order to obtain...
Ngày tải lên: 30/03/2014, 09:20
labor market transitions of involuntary part-time workers how hard is it to get back to full-time jobs
... residential areas and transition probabilities are discussed in recent underemployment studies, the focus is not on involuntary part-time employment The focus in this study is to better understand ... are used to create pooled short-panel data sets for this purpose Separate models are estimated for men and women This dissertation departs from existing involuntary part-time employment studies ... workforce in the U .S. , and the ability of this workforce to secure better jobs over time at least in terms of hours if not also benefits and higher wages Secondly, this study estimates multinomial...
Ngày tải lên: 03/06/2014, 02:05
báo cáo hóa học:" AIDS-associated Kaposi’s sarcoma is linked to advanced disease and high mortality in a primary care HIV programme in South Africa" pdf
... our post hoc sensitivity analysis Finally, other risk factors for mortality, such as other opportunistic infections like tuberculosis, were not considered years) despite better access to treatment ... patients with AIDS-KS are needed Baseline CD4 count of less than 100 cells/mm3 was associated with mortality on univariate analysis, but not on multivariate analysis This is likely because the ... time, months Disseminated Cutaneous Lesions IRIS Table Associations with mortality in AIDS-KS patients Mortality 112 (59) Unadjusted 34(29-41) 82 (31-174) HR Site of Kaposi s sarcoma Lesions Oral...
Ngày tải lên: 20/06/2014, 08:20