as apr and aal spermatogonia during the epithelial cycle

... MLL and H3K4 methylations during cell cycle in S phase may not be the same as the marks in other phases of the cell cycle (as shown by immunofluorescence staining and western blotting); rather, ... 6C,D) In the case of the HoxA7 gene promoter, the recruitment of RNAP II and MLL1 and the level of H3K4 trimethylation were low at the beginning (S phase) and gradually increased as the cell progressed ... cells were released at the S phase In the case of HoxA5, recruitment of RNAP II and MLL1, and the level of H3K4 trimethylation in the promoter, were low at S phase (0 h), increased by 1.7-fold...

Ngày tải lên: 23/03/2014, 06:20

... performed the zymography, the MMP activity assay and the cytokine ELISAs US wrote the manuscript BW and RB supervised the project and gave helpful comments about the manuscript All authors read and ... metalloproteinase MMP-3 was heavily induced in the acute phase of AIA and showed the most impressive increase of expression on days and (Fig 2a) Its expression level decreased in the chronic phase in comparison ... PCR The cathepsins B and H were non-significantly overexpressed in the acute phase The mRNAs for cathepsins L and S were significantly elevated on day in murine knee joints, where arthritis was...

Ngày tải lên: 09/08/2014, 06:22

... performed the assessment and analysis of the protein data and participated in writing the manuscript AS, EB, and CBSW assessed and analyzed the mRNA data EPK critically read and edited the manuscript ... elevated in the LN than in the SM [19], in line with the different mode of induction of the disease, which favors spread of the arthritogen to the regional LNs [23] Both the pathology and the sequence ... elevation, whereas the increases for TNF-α were 3.5-fold and 2-fold for mRNA and protein, respectively In the SM, there were significant elevations of both IFN-γ and IL-2 mRNA in the acute phase (Figs...

Ngày tải lên: 09/08/2014, 06:22

... extensive investigation and treatment was referred to the Polyclinic The purpose of this study was to report foot and ankle injuries at the 2004 Athens Olympic Games and to assist in the planning of ... presented to the Foot and Ankle Department for treatment The mean age of athletes was 24 years (range 21 to 32), whereas the mean age of the media, Olympic family and officials was older at 42 ... training and/ or matches as a result of the injury All team sports, as well as the athletes which were included in this report, followed the same methodology Information was collected from the logbooks...

Ngày tải lên: 10/08/2014, 21:23

... subject was informed of all procedures, potential risks, and the benefits associated with the study This was done through verbal and written form in accordance with the approved procedures of the ... postprandial period to allow for anabolism [34] For cortisol, a further lowering during the postprandial period may be viewed as positive, as lower cortisol may be associated with decreased proteolysis ... gather data regarding how these hormones are affected during a 24 hour cycle This would further clarify whether the changes in cortisol and testosterone are indeed impacted by feeding or if they...

Ngày tải lên: 11/08/2014, 23:21

... random occasions, usually family gatherings When measuring time occurs the grandchildren stand against the board, a line is drawn at the top of their head, and the date of the line is noted The ... cells, then a priori there should be evidence of an approach to exponential mass increase If the rate of mass increase during the first cycle is 1.0, during the second cycle it should be 2.0, during ... exponential growth the absolute increase in cell mass increases during the division cycle, but with linear growth the absolute increase in cell mass is constant during the division cycle Problems...

Ngày tải lên: 13/08/2014, 23:20

... using the Benjamini-Hochberg method in Acuity For Class II genes, the two groups were all the serum treated samples as one group, and all the GF treated samples as another For Class III genes, the ... signaling events they may regulate [32] DGKs, such as DGKA, DGKD, and DGKZ, were among the serum repressed Class II genes and PKC (PRKD3) was in the serum upregulated set Taken together, these observations ... produced by the activation of the phosphoinositide pathway is the physiological activator of protein kinase C (PKC) as well as other protein kinase C conserved region (C1)-domain proteins, such as protein...

Ngày tải lên: 14/08/2014, 16:21

... most other land was barren, and not sizable enough for the dwellers either Most people could only cultivate the poor land near the mountains Furthermore, most of the land was owned by landlords ... and other places.‖83 After the Tongzhi reign, the Gelaohui began to expand to Hubei, Hunan and other places in the Yangtze River valley During the Guangxu reign (1875-1908), the Gelaohui expanded ... their face was pale and eyes livid They traveled on the main road, stopped at the crossroad, asking those passersby for food and money They slept on a bale of straw in the open air Many of them died...

Ngày tải lên: 16/10/2015, 15:38

... chromosomes and showed it to be the same as in the nucleus Phosphorylation at site increased in the nucleus during phases G1 and S, and was detected in the cytoplasm during the M phase Phosphorylation ... increased gradually in the nucleus during phases S and G2, and was detected maximally in the cytoplasm in the M phase The timing of phosphorylation and dephosphorylation of MCM4 during phases G2 and ... -32, -54 and -110) and propidium iodide (10 lM), and observed using a confocal laser scanning microscope Cells in the M phases (prophase, prometaphase, metaphase, anaphase and telophase) were...

Ngày tải lên: 16/03/2014, 13:20

... contained in the extracts The inhibitory activity during the cell cycle The inhibitory activity during the cell cycle was measured in the presence of 0.4 U of (added) purified DNA polymerase a and the ... other DNA polymerases in the extract Standard DNA polymerase activity and inhibition assays Total DNA polymerase activity was assayed as described previously [12] The standard assay contained ... [17] and another to the carriage and storage of DNA polymerases, histones, and other nuclear proteins in the plasmodium [2,18] In connection with the role as a carrier and storage function, the...

Ngày tải lên: 31/03/2014, 21:21

... originates in the epithelium, targets pulmonary vascular cells and influences lung vascularization during the alveolar and microvascular maturation phase of lung development Competing interests The authors ... daily from PN3-14; (3) DEX and RA at doses and days as above; (4) saline and CSO at doses and days above; and (5) control (same handling, no injections) The dose of DEX was based on previous literature ... established that epithelial cell purity by this procedure is 83 ± 2%, with fibroblasts as the primary contaminating cell type [14] Fibroblasts from the same fetal lung tissue were recovered as the adherent...

Ngày tải lên: 12/08/2014, 14:20

... difficulties, flashbacks, headaches, and intrusive thoughts based upon their experiences during the disaster, such as awareness of people drowning and dying, or guilt and anxiety over children and relatives ... even in the best of times and that also in resort areas Inland freshwater pools classically contain Gram-negative bacilli such as Pseudomonas species, Aeromonas, Plesiomonas, as well as Burkholderia ... relatives and psychotherapeutic support was introduced as early as possible The service was provided by the department's psychotherapeutic intervention team consisting of three qualified and experienced...

Ngày tải lên: 12/08/2014, 23:23

... bronchial epithelial cells (Table 2), with occasional and weak staining of alveolar type II epithelial cells, macrophages and vascular endothelial cells (Figure 4a) In the IIR group, the staining was ... increase of VEGF in the BAL fluid was found from both the sham and IIR groups (Figure 2a), while no difference in the plasma levels of VEGF was found among the groups (Figure 2b) The expression and ... when EBD assay was used to further assess the pulmonary permeability, a significant increase in the BAL/plasma EBD ratio was only detected in the IIR group (Table 1) After h of reperfusion, the lung...

Ngày tải lên: 13/08/2014, 03:20

... 0=no pain and 10= worst imaginable pain Agrawal et al used both, 4-point scale and VAS, in which the first scaling was used during the canulation and VAS was used after the canulation They found ... pain” and 10 = “worst imaginable pain” VAS scores of 1- were rated as mild, 4–6 as moderate, and as severe Median (interquartile range) VAS score in the balloon group was (3), which was reduced as ... ISI, and other databases This intervention was noninvasive and previous studies reported that baroreceptor activation induces nociception This trial was then registered with and approved by the...

Ngày tải lên: 25/10/2012, 11:15

... sludge was higher in the first reaction tank, and then decreased to the downstream This behavior suggests that PHA accumulation was firstly occurred and then PHA was consumed in the course of wastewater ... reactors, the value of conversion rate to PHA, CRP value, was calculated as the amount of PHA increased during the anaerobic phase divided by the amount of carbon supplied as influent in one cycle ... diameter and 0.4µm film thickness) The temperatures of the detector and the injector were set at 250°C and 180°C, respectively Column temperature was kept at 60°C for minutes, then increased at...

Ngày tải lên: 05/09/2013, 09:38

... almonds, has low toxicity to mammals, and has widespread use in topical antiseptics 16.2 The Materials and Methods The materials and methods employed in the current study are described as follows The ... animals and humans They are also classified as generally recognized as safe (GRAS) The ultimate goal is the introduction of these phytochemicals with low toxicity, which comply with health and environmental ... Oryzaephilus, Rhyzopertha, and Sitophilus In the case of larvae and pupae, Trogoderma was the most tolerant, followed by Tribolium and Plodia (Table 16.7) CS2 was less effective than CH3 I and needed a concentration...

Ngày tải lên: 25/10/2013, 05:20

... 1998; Gasse, 2000; Zabel et al., 2001) During cold and arid phases much of Africa between approximately Africa and Eurasia during the last glacial cycle 145 5◦ N and 35◦ N, as well as eastern and ... east Asia and indicate that a treeless landscape with a tundra flora Africa and Eurasia during the last glacial cycle 139 and fauna predominated (Coope, 2002) Evidence from other sites across the ... glacial cycle (125–0 kyr) that has been the coolest and most variable period and that which saw the arrival of Moderns into Eurasia and the extinction of the Neanderthals It was characterised by the...

Ngày tải lên: 01/11/2013, 07:20

... envelopes, predict the future and explore the past, and the like They can so, says Schubert, because The pursuit of the subject –  the circumvention of consciousness releases the inherent ... philosophy, its task communicatively to realise those ideas Where Schiller had seen the poet as the only true human being and the age as sick, Hardenberg sees the transcendental poet as the transcendental ... is anamnesis, the re-call and re-presentation of the past, so that the past’s meaning thereby becomes present, and Hyperion’s ascent to higher vision is enacted in the text Stranded in philistine...

Ngày tải lên: 01/11/2013, 09:20

Ngày tải lên: 13/02/2014, 12:20

... altitude During the passage of the extratropical cyclone in the heart of the heat wave period, the change of air masses and the lowering of the top of the planetary boundary layer reduces the height ... dynamics of the weak extratropical low, bypassing the western and northern edge of the anticyclone from Portugal to United Kingdom and then moving towards the southeast over Frankfurt The MOZAIC ... not measured in the lower troposphere during descents and in the whole troposphere during ascents Based on the dual-beam UV absorption principle (Thermo-Electron, Model 49-103), the ozone measurement...

Ngày tải lên: 17/02/2014, 10:20