arp warp and automatic interpretation of protein electron density maps

... the connectivity of the positive density in the man.15 Another feature of protein crystals is the presence of distinct regions of protein and solvent The electron density maps in protein regions ... scattering of X-rays both over time and over the many repetitions of the protein in the crystal, the electron density in the solvent region is generally flat In contrast, the electron density in the protein ... for refinement and model building with high-resolution data have been developed (wARP /ARP; Perrakis et al.2,3) The separate automation of structure solution and of model building and refinement...

Ngày tải lên: 11/04/2014, 09:49

... M¨ ller is a Professor of electrical u engineering and Head of the Circuit and System Design Group at Chemnitz University of Technology His research interests include VLSI design and field-programmable ... from both the University of Dresden and Chemnitz University of Technology He is a Member of the Association for Electrical, Electronic, and Information Technologies (VDE) and the Information Technology ... engineering from Chemnitz University of Technology He is appointed Professor of digital systems at Lippe and Hoexter University of Applied Science Volker Lohweg is a Member of the German Association for...

Ngày tải lên: 23/06/2014, 01:20

... thể thấy nơ ron hoàn toàn mô khả tính toán mạch sở AND, OR, NOT X X w =1 =1,5 w =1 Z =0,5 w =1 w =1 Nhập môn xử lý ảnh số - ĐHBK Hà nội Y Y Z = X and Y Z = X or Y Z X w=-1 =-0,5 174 Y = not X Y ... Sử dụng mạng khả biểu diễn mạng Nh phần nhập môn, nơ ron riêng lẻ biểu diễn hàm logic sơ cấp nh: AND, OR, NOT Từ hình dung lớp hàm tính dợc nhờ mạng nơ ron Perceptron tơng đối phong phú Sau số...

Ngày tải lên: 27/08/2012, 10:19

Ngày tải lên: 21/02/2014, 21:56

... language structure and syntax, and therefore a basic understanding of the principles of object-oriented programming (OOP) ❑ Good working knowledge of the NET Framework ❑ A grasp of the Visual Studio ... the Command had some initial appeal: ❑ Intent of GoF Command: Encapsulate a request as an object, thereby letting you parameterize clients with different requests, queue or log requests, and support ... subclasses redefine certain steps of an algorithm without changing the algorithm's structure ❑ Intent of GoF Strategy: Define a family of algorithms, encapsulate each one, and make them interchangeable...

Ngày tải lên: 14/03/2014, 21:20

... corpora: (i) a version of section 23 of the Penn Treebank from which empty nodes, indices and unary branching chains consisting of nodes of the same category were removed, and (ii) the trees produced ... consists of the triple of category plus string positions as above, together with the set of triples of all of the non-empty nodes the empty node is co-indexed with (Usually this set of antecedents ... (section 23 of the Penn Treebank); these are ordered by frequency of occurence in the gold standard Section 23 is a test corpus consisting of a version of section 23 from which all empty nodes and indices...

Ngày tải lên: 17/03/2014, 08:20

... for protein quantification Normalization of protein loading on each blot was obtained by loading a volume of sample of conditioned medium standardized to total cell lysate protein concentration Proteins ... the effect of phorbol esters on sAPPa release in spite of the presence of unchanged levels of two other Ca2+-dependent PKC isoforms, PKC bI and bII, and at least one Ca2+-independent isoform, PKCd ... role of PKC isoforms in APP processing (Eur J Biochem 271) 3069 sAPPa We have therefore studied the direct and receptormediated activation of PKC in a cellular model of downregulation of PKCe and/ or...

Ngày tải lên: 23/03/2014, 13:20

... hemolin binds to the surface of Gramnegative and Gram-positive bacteria and yeast, and caused aggregation of these micro-organisms Binding of hemolin to the surface of bacteria appears to be due ... O-antigen and may also lack parts of the outer and inner core polysaccharide We performed competitive binding assays to test binding of different moieties of LPS to M sexta hemolin Binding of hemolin ... that hemolin binds smooth forms of LPS most efficiently, but rough forms of LPS, lacking the O-antigen and parts of the inner-core and outer-core polysaccharide, and lipid A alone could also partially...

Ngày tải lên: 31/03/2014, 09:20

... “Handbook of Statistics 2: Classification, Pattern Recognition and Reduction of Dimensionality,” North-Holland, Amsterdam, 1982 T Y Young and K S Fu (eds.), “Handbook of Pattern Recognition and Image ... These are defined by (2.31) and (2.32) Note that all components of (2.31) and (2.32) are special cases of (2.25) Therefore, M and are unbiased and consistent estimates of M and S respectively Introduction ... summation of N random variables, it is also a random variable and characterized by an expected value and variance The expected value of m, is l h (2.28) That is, the expected value of the estimate...

Ngày tải lên: 31/03/2014, 16:24

... with some of the greatest minds in the industry It has required hundreds of thousands of hours of computer programming, and the analysis of millions of charts It has required the formation of a dedicated ... the Rule of Alternation, we have found that Waves and don'alternate as often as t expected Wave Sharp Sharp Sideways Sideways Alternating Wave Sharp Sideways Sharp Sideways Percent of Total 8.7% ... average of 80% Real probabilities ranged up to four times more likely than random We checked, and then double-checked the results And The Implications Are: The implications of this research are profound...

Ngày tải lên: 16/04/2014, 16:26

... sense of lots of columns of numbers, but a computer program hasn't got eyes The computer program has to be an embodiment of a set of rules which operates on a collection of columns of numbers, and ... for any value of a, b and c, and attach a sign, + and -, to each side of the line This is done in Fig.1.7, for two choices of the weights a,b and c With the choice a = 1, b = -1 and c = 100, we ... height of 200 cm and weighs in at 100 kg, and Gladys who has a height of 150 cm and a weight of 60 kg We can picture them graphically as in Fig.1.5., or algebraically as Figure 1.5: Gladys and Fred,...

Ngày tải lên: 18/04/2014, 10:47

... reading and the serious comments and suggestions of Prof G Moustakides, Prof V Digalakis, Prof T Adali, Prof M Zervakis, Prof D Cavouras, Prof A Bohm, Prof G Glentis, Prof E Koutsoupias, Prof V ... with the basics and moves progressively to more advanced topics and reviews upto-date techniques A number of problems and computer exercises are given at the end of each chapter and a solutions ... without the constant support and help from a number of colleagues and students throughout the years We are especially indebted to Prof K Berberidis, Dr E Kofidis, Prof A Liavas, Dr A Rontogiannis,...

Ngày tải lên: 18/04/2014, 12:33

Ngày tải lên: 24/04/2014, 12:25

... follows: Union and Intersection The union of G and G is the graph G = G ∪ G = (V ∪ V , E ∪ E ), i.e., the vertex set of G is the union of V and V , and the edge set is the union of E and E , respectively ... maps pairs of elements of V (G) (not necessarily distinct) to elements of E(G) The elements vi of the set V (G) are called vertices (or nodes, or points) of the graph G, and the elements ej of ... spanning k-tree of G, where k is the number of component of G A forest is simply a set of trees, spanning all the vertices of G A connected subgraph of a tree T is called a subtree of T If T is...

Ngày tải lên: 24/04/2014, 12:34

... Given two classes of points, find their centers of mass, and label new points according to the nearest center of mass www.support-vector.net 41 Parzen Windows ! Center of mass of a class is: C= ... dimension of space (can be huge) www.support-vector.net 23 Assumptions and Definitions ! distribution D over input space X ! train and test points drawn randomly (I.I.d.) from D ! training error of ... on the risk of overfitting (in a p.a.c setting: assumption of I.I.d data; etc) ! Standard bounds from VC theory give upper and lower bound proportional to VC dimension ! VC dimension of LLMs proportional...

Ngày tải lên: 24/04/2014, 13:39

... of cells, as indicated here for the case of d = 3, and to specify the value of y for each of the cells The major problem with this approach is that the number of cells, and hence the number of ... many of the fundamental concepts of statistical pattern recognition by considering a simple, hypothetical, problem of distinguishing handwritten versions of the characters 'a' and 'b' Images of ... that the ratio of the volume of a hypersphere of radius a to the volume of a hypercube of side 2a (i.e the circumscribed hypercube) is given by volume of sphere _ ird/2 = d ( volume of cube d2 -»r(d/2)'...

Ngày tải lên: 24/04/2014, 14:04

... adjusted with elbows, preserving the sterility of scrubbed hands She pulls off her sweater and T−shirt and, using hands, not elbows, starts the shower and adjusts the temperature FOUR hours later ... with trestles and card tables, and by the shoppers clustered around them The sun has come fully and unexpectedly out, and between the sun and the crowd and the residual wonky affect of soul−delay, ... consist of, here and now, but then she thinks of F:F:F and the frenzy of posts the new footage will have generated She'll make a pot of tea−sub, cut up an orange, sit cross−legged on Damien's carpet,...

Ngày tải lên: 28/04/2014, 09:51

... cover all stages of an investigation from problem formulation and data collection through to discrimination and classification, assessment of results and interpretation Some of the basic terminology ... recognition theory and techniques Most of the material presented is concerned with discrimination and classification and has been drawn from a wide range of literature including that of engineering, ... on the basis of a training set of samples Given this training set, we may choose to form estimates of the distributions (using some of the techniques discussed in Chapters and 3) and thus, with...

Ngày tải lên: 28/04/2014, 09:51

... illustrated in Figure 1.9 Now suppose we randomly pick one of the boxes and from that box we randomly select an item of fruit, and having observed which sort of fruit it is we replace it in the box ... pick the red box 40% of the time and we pick the blue box 60% of the time, and that when we remove an item of fruit from a box we are equally likely to select any of the pieces of fruit in the box ... sample both of the variables X and Y , and let the number of such trials in which X = xi and Y = yj be nij Also, let the number of trials in which X takes the value xi (irrespective of the value...

Ngày tải lên: 28/04/2014, 09:51