... Figure Structural characteristics of HIV-1 activating HDACIs Structural characteristics of HIV-1 activating HDACIs Panel A: Docking of the HDACI MC2211 at the catalytic cavity of HDAC2, a class I ... and MC2211 within the catalytic cavity of HDAC2 Inhibitors are shown in CPK (MC2113: carbon backbone in white; MC2211: carbon backbone in cyan) The enzyme backbone is shown as cartoons The Zn++ ... toxicity of the HDACI trichostatin in ACH-2 cells than in their uninfected counterparts and linked this phenomenon to the cytotoxicity of activated HIV-1 replication in lymphoid cells [16] In...
Ngày tải lên: 12/08/2014, 23:21
... been introduced as a compulsory subject, the teaching and learning of ESP in general and reading skills in particular are still far from being satisfactory To be more exact, the Communicative ... lessons according to the teachers …………………………………………………………… 33 Chart 3.10 Types of classroom interaction used during reading lessons according to the students ………………………………………………………… 33 Chart 3.11 The ... and the observation The findings, comments and conclusions are also given; − Chapter IV suggests some techniques for each stage of a reading lesson They are carried out in the light of Communicative...
Ngày tải lên: 07/09/2013, 13:45
Idioms with as as in comparison with the vietnamese ones = nghiên cứu thành ngữ so sánh trong tiếng anh và tiếng việt
... referring to peoples appearance, character, mental state and health state, we can see the specific characteristics of each country in combination with mankind characteristics Another thing that ... idioms in the articles/letters and listing them After one article/letter, the teacher ask the students to find the idioms and number them on the list in the order in which the students find them Then, ... justice for carefully considered the pros and cons of the country, and chaos would ensue each Although he acknowledged the cultural convicting the bewildered men of their differences in their background,...
Ngày tải lên: 19/12/2013, 10:39
programming in c# with visual studio 2010 vol i (microsoft)
... specify the following settings for the project, and then click OK: a In the Installed Templates list, under Visual C# , click Windows b In the center pane, click Console Application Introducing ... the assemblies in the GAC This can include installing and uninstalling assemblies in the GAC so that multiple applications can access them Introducing C# and the NET Framework Tool 1-15 Description ... defined in the NET Framework, perform the following tasks: Add a reference to the assembly that contains the compiled code for the class Bring the namespace that contains the class into scope If...
Ngày tải lên: 24/01/2014, 19:37
programming in c# with visual studio 2010 vol II (microsoft)
... Setting the string – calls the set accessor theClass.MyString = "Property set."; // Getting the string – calls the get accessor Console.WriteLine(theClass.MyString); Note: You can define static ... Implement the IMeasuringDeviceWithProperties interface Modify the class declaration to implement the IMeasuringDeviceWithProperties interface instead of the ILoggingMeasuringDevice interface The IMeasuringDeviceWithProperties ... restrictions In this case, you can add logic to the get accessor to log access or to further restrict access according to business requirements Use Naming Conventions The convention when wrapping...
Ngày tải lên: 24/01/2014, 19:43
Tài liệu Pragmatic Unit Testing in C# with NUnit pptx
... TRUCTURING U NIT T ESTS AccountTest.cs CreateSimpleAccount() CreateDefaultAccount() CreateDupAccount() (Internal Only) Account.cs CreateAccount() (Delivered) Figure 3.1: Test Code and Production ... (instead of just the printed fragment), look in the margin: the filename of each code fragment in the book is printed in the margin next to the code fragment itself Some code fragments evolve with ... all the native types (int, decimal, etc.) and Object Strings and Collections also have their own classic-style asserter classes with extra methods, StringAssert and CollectionAssert, which we’ll...
Ngày tải lên: 16/02/2014, 13:20
Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf
... interacts directly with Ca2+⁄ CaM and that PhK13 does not The PhK5 interaction causes a large conformational change to occur in Ca2+⁄ CaM that produces a classical compact Ca2+⁄ CaM ⁄ peptide complex ... the ‘compact’ structure of a Ca2+ ⁄ CaM ⁄ peptide complex The N-terminal domain is in blue and the C- terminal domain is in pink The peptide is shown as a green helix and the termini are indicated ... with Ca2+ ⁄ CaM ⁄ PhK5 Ca2+ ⁄ CaM ⁄ smMLCK is shown in pink once again as a reference Ca2+ ⁄ CaM ⁄ CaMKK is in red (PDBid 1iq5), Ca2+ ⁄ CaM ⁄ CaMKIIa is shown in green (PDBid 1cdm) and the Ca2+...
Ngày tải lên: 19/02/2014, 17:20
Programming 8-BIT PIC Microcontrollers in C with interactive hardware simulation pot
... of Labcenter Electronics Ltd Custom Computer Services Inc (www.ccsinfo.com) Custom Computer Services Inc specializes in compilers for PIC microcontrollers The main range comprises PCB compiler ... RISC (reduced instruction set computer) processor Looking at the internal architecture, we can identify the blocks involved in program execution The program memory ROM contains the machine code, ... restarted in an orderly way Code Protection (CP) The chip can be configured during programming to prevent the machine code being read back from the chip to protect commercially valuable or secure code...
Ngày tải lên: 06/03/2014, 17:20
ORIENTATION PAPER prepared in connection with the FP7 2013 Work Programme in the area of Health research docx
... to advance promising new therapeutic vaccines into clinical safety and efficacy testing Chronic infectious diseases (including infections in immunocompromised patients), inflammatory and autoimmune ... conduct of clinical trials Specific guidance on important information to be included in proposals involving clinical trials as well as specific information on the financing of clinical trials under ... effects in specific patients The technologies should be of use as biomarkers during the therapeutic interventions Clinicians should actively be included in the project Note: Limits on the EU financial...
Ngày tải lên: 07/03/2014, 04:20
Pioneer Introduces the New CYBER NAVI Car Navigation system in Japan With the world’s first* Head-Up Display to project augmented reality information in front of the windscreen* pot
... distance indicator The lock-on range for the target that indicates the distance between the driver’s vehicle and the vehicle in front has been extended The size and color of the inter-vehicular ... media microSD memory cards and microSDHC memory cards (Version 2.0) supported Connection protocols Bluetooth 2.1+EDR ■Cruise scouter unit Not included Not included Inclusions Included Included ... g (including the stay) Camera component (including the cover): 260 g; Main unit: 450 g 25 g - 2.6 kg 2.1 kg 1.1 kg - AVIC-ZH77: Main specifications AVIC-ZH77 ■Main navigation unit (common components)...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... GCSFR using the oligonucleotides: 5¢-ACTACCGAACGGGCCCCCGGGGTC AGACTGGACACATGG-3¢ and 5¢-TCGGGCCATGGC ATGCCCGGGGGTCAGAGCTGGG-3¢ for amplification of D4 of GCSFR and 5¢-TACTCTCAAGAAATG CCCGGGTCCCATGCCCCAGAG-3¢ ... CCCGGGTCCCATGCCCCAGAG-3¢ and 5¢-GCCCAG GATGATGTGTAGCTCCCCGGGCTCTGGGGTCAA GGT-3¢ for D6 of GCSFR (the XmaI sites are underlined) as PCR primers Starting point for cloning of gp130 C4 58A, C4 66A and C4 91A ... bond between the remaining cysteines C4 66 and C4 91 of gp130 This could result in a conformational change within the receptor chain enabling the activating interaction with the LIFR Another explanation...
Ngày tải lên: 18/03/2014, 01:20
synthesis of wo3 in nanoscale with the usage of sucrose ester
... Unlike the alkyl ethoxylates, the sucrose esters not significantly change their HLB with increasing temperature Consequently, increasing the temperature does not induce a phase inversion in microemulsion ... solutions, the microemulsion containing ammonia solution was added to the other microemulsion containing tungsten (VI) chloride The mixed microemulsion was stirred for h at about 45 C Then the mixed ... C in the nanoparticles The existence of C impurity in nanoparticles is believed to originate from environmental contamination and also the residual surfactants absorbed on the nanoparticles The...
Ngày tải lên: 20/03/2014, 13:08
Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx
... and outcomes from the NCIN Tackling cancer inequalities A number of different groups in society experience unacceptable inequalities in cancer The nature of these inequalities in cancer is complex, ... addressing the continuing regional variations in access to new drugs in the absence of NICE decisions • Ensure local action plans are developed to reduce waiting times by increasing capacity in the ... more closely connected to Cancer Research UK through knowing more about the work of their local Cancer Research UK Centre and by coming into contact with our health information and campaigning activities...
Ngày tải lên: 22/03/2014, 16:21
Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf
... in the authentic ribose-binding proteins In addition, the repressor sequences include a DNA-binding headpiece, and so are consistently longer than those of the binding proteins, even if one includes ... interacting directly (via either van der Waals interactions or hydrogen bonds) with the monosaccharide unit in the current complex are marked with cyan, and those specifically related to the glyceryl ... two molecules indicates that their conformation is affected very little by differences in crystal packing Comparison with the structures of Salmonella GBP in complex with galactose (1GCA) [21]...
Ngày tải lên: 23/03/2014, 04:21
In Partnership with the Government of Kenya: Kenya Strategy 2011-2014 doc
... training on best practices for pneumococcal vaccine introduction JICA: Supports cold chain procurement Glaxo-Smith Kline: Will supports studies on adverse effects for the new pneumococcal vaccine ... Supporting TB vaccine evaluations Malaria Vaccine Initiative (Gates Foundation): Supports malaria vaccine evaluations Coordination/integration: Further integrating efforts and coordinating with ... neonatal infections Infancy, child and mother care: Improved care during infancy includes attention to a variety of home and community interventions aimed at preventing common childhood infections...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand pdf
... 5¢-AATTAACCCTCACTAAAGGG-3¢ 5¢-GTAATACGACTCACTATAGGG-3¢ 5¢- AATCCGTCGAGCAGAGTT-3¢ 5¢-CTGGCCGTCGTTTTACTTAGGGTTAGGGTT AGG-3¢ 5¢- GTAAAACGACGGCCAG-3¢ 5¢-GTACAGTGTACAGTGTACAGT-3¢ 5¢ biotin-GTAATACGACTCGTTAGGGTTAGGGT ... done in the absence of proteins In subsequent lanes, the reactions were done with 75 mM fraction as the protein source and in the presence of increasing concentration of competitor All three complexes ... gel, in- gel digested with trypsin (sequencing grade porcine trypsin, Promega), according to the University of California, San Francisco (UCSF) Mass Spectrometry Facility in- gel digestion procedure...
Ngày tải lên: 23/03/2014, 13:20
An Introduction to Design Patterns in C++ with Qt™, 2nd Edition doc
... just before the compiler compiles your code In this example, http://www.gnu.org/software/gcc/onlinedocs/ Discussed in Section C. 2 www.it-ebooks.info Chapter C+ + Introduction the included header ... remove the following line? using namespace std; • Replace the statement cin >> yourName; with the statement getline(cin, yourName); and try Curious George again • Can you explain the differences in ... further in Section 1.9 10 We discuss classes in detail in Chapter 2, “Top of the class. ” For now, you can think of a class as a data type with built -in functions www.it-ebooks.info 1.5 Introduction...
Ngày tải lên: 24/03/2014, 01:21
Báo cáo khoa học: Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP potx
... hydrophobic sandwich (Fig 3B and C) The Tyr450 side chain interacts extensively with the a-amino acid group, as well as with C4 , C5 , C6 and C7 of the seven-membered ring Leu650 interacts with the isoxazole, ... (S)-4-AHCP complex, the tail of this side chain skirts the binding pocket to avoid clashing with the ligand The Ce atom of Met708 points back into favourable van der Waals contact with the sevenmembered ... domain closure Secondly, driving the domains closer to each other would result in steric clashes between the bicyclical ring system of (S)-4-AHCP and the backbone atoms of Leu704 Also, the side chains...
Ngày tải lên: 30/03/2014, 16:20
pro android c with the ndk
... license and will ask you to accept the terms of the license agreements in order to continue with the installation Review the license agreements, choose to accept their terms, and then click the ... Eclipse IDE Checking the GNU C Library Version You can check the GNU C Library version by executing ldd version on a Terminal window, as shown in Figure 1-46 Figure 1-46. Checking the GNU C ... NDK installation directory to keep things safe Check the “Copy projects into workspace” option to ask Eclipse to copy the project code into the workspace, so that you can operate on a copy rather...
Ngày tải lên: 28/04/2014, 16:44
Báo cáo khoa học: "Genetic variation of the Croatian beech stands (Fagus sylvatica L): spatial differentiation in connection with the environment" doc
... forests located along the northern slope of the Dinaric Alps, on the plain and in the highlands of Croatia With regard to soil factors, we could only define classes of pH (acid, neutral and basic); ... then carried out a discriminant analysis including only the loci for which previous comparisons displayed significant differences Only one allele was taken into account for each diallelic locus ... Sampling Sampling was carried out in 35 beech stands representing the various climatic conditions, the various soils and topographic locations where beech grows in Croatia (fig 1, table I) In each...
Ngày tải lên: 08/08/2014, 23:21