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Báo cáo y học: " Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients" pdf

Báo cáo y học: " Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients" pdf

Ngày tải lên : 09/08/2014, 01:24
... be a marker of disease activity The group of Varley and Munford [57] showed that the acute-phase proteins complement factor (C3) and serum amyloid A- 3 are particular attractive candidates for ... signalregulated kinase are two signalling pathways of the cytokine receptor gp130, and adenovirally mediated Ras DN gene transfer into rat ankle joints ameliorated adjuvant arthritis [69] The disadvantage ... T, Kadono Y, Sawada Y, Nakamura I, Katagiri H, Asano T, Tanaka Y, et al.: Suppression of arthritic bone destruction by adenovirus-mediated dominantnegative Ras gene transfer to synoviocytes and...
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báo cáo khoa học: "Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?" docx

báo cáo khoa học: "Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?" docx

Ngày tải lên : 11/08/2014, 12:21
... predictive performance on independent datasets Larger datasets and new analytical platforms (such as next generation sequencing) that broaden the portfolio of variables that can be used for model ... It seems that fewer genes are associated with outcome in homogeneous disease subsets and the magnitude of association is modest when currently available datasets are analyzed This leads to predictors ... tools to the data, may also reveal additional prognostic information that is not readily revealed by studying gene-expression levels alone New analytical platforms, such as next generation sequencing,...
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Báo cáo y học: "Are we ready for therapeutic drug monitoring of biologic therapeutics" pot

Báo cáo y học: "Are we ready for therapeutic drug monitoring of biologic therapeutics" pot

Ngày tải lên : 12/08/2014, 17:22
... Krieckaert CL, Nurmohamed MT, van Schouwenburg PA, Lems WF, Twisk JW, Dijkmans BA, Aarden L, Wolbink GJ: Development of antidrug antibodies against adalimumab and association with disease activity ... biological response Although measurements of antibodies and trough serum drug concentrations are not widely available (particularly for the new biological therapeutics) and additional research questions ... thromboembolic events in adalimumabtreated patients with antiadalimumab antibodies: a case series and cohort study Arthritis Rheum 2011, 63:877-883 Wolbink GJ, Aarden LA, Dijkmans BA: Dealing with immunogenicity...
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Accounting standards are we ready for principles based guidelines

Accounting standards are we ready for principles based guidelines

Ngày tải lên : 04/03/2017, 10:52
... financial statements accurately communicate the financial performance of a company What about regulators, investors, and analysts? standards? Do they prefer detailed PwC: Where the facts in a ... characteristics that make accounting information useful and are discussed in detail in Concepts Statement As noted earlier, all of the standards that the FASB issues are based on the concepts Statements and ... guidance that differentiates a “principles-based” standard from a “rules-based” standard—not consideration of the qualitative characteristics Detailed rules-based standards are generally thought...
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PD 3003:2002 Are you ready for a BS 77992 audit?

PD 3003:2002 Are you ready for a BS 77992 audit?

Ngày tải lên : 18/08/2017, 10:15
... for example, to having an internal ISMS audit or a 2nd party audit carried out by a customer For accredited certification the gap analysis has no formal status and cannot be taken to form an approved ... compliance with BS 7799 Part Page Are you ready for a BS 7799 Part Audit?” Organizations may use the gap analysis to make an informal assessment of their compliance with BS 7799 Part prior, for ... Enter a wider explanation of the reason(s) indicated above Where aspects are already addressed it may be helpful to detail them Page 10 Are you ready for a BS 7799 Part Audit?” BS 7799-2:2002 Information...
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PHÂN TÍCH báo cáo NGHIÊN cứu state owned enterprises (SOEs) in vietnam perceptions of strategic direction for a society in transition

PHÂN TÍCH báo cáo NGHIÊN cứu state owned enterprises (SOEs) in vietnam perceptions of strategic direction for a society in transition

Ngày tải lên : 24/12/2013, 23:11
... ngh a Trong khuôn khổ môn học Phương pháp nghiên cứu khoa học, nhóm phân công phân tích báo cáo nghiên cứu có đề tài "State-owned enterprises (SOEs) in Vietnam - Strategic direction for a society ... tài: “State-owned enterprises (SOEs) in Vietnam Perceptions strategic direction for a society in transition” Tạm dịch: Nhóm - Lớp Đêm - K22 Tiểu luận môn PPNCKH GVHD: TS Đinh Thái Hoàng date]TiTi6 ... lãnh đạo vấn, ý định cấu lại doanh nghiệp họ kinh tế cạnh tranh toàn cầu kinh tế Việt Nam ch a hoàn toàn mở c a để doanh nghiệp cạnh tranh cách tự do, bình đảng Thứ hai, tác giả tiếp tục phân tích...
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Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc

Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc

Ngày tải lên : 16/03/2014, 04:20
... Merilainen et al ¨ Table Calorimetric analysis of CoA binding to the Z ramigera biosynthetic thiolase at 25 °C The values and error estimates are calculated from separate measurements (three for ... interactions at the thiolase active site liquor, was allowed to continue for days prior to data collection This experiment was performed for both a wildtype thiolase crystal and a C8 9A mutant ... AcAc-SPP [3]; for example, Km and kcat are 73 lm and 469 ⁄ s for AcAc-SPP, whereas they are 24 lm and 465 ⁄ s, respectively, for AcAc-CoA In the crystal structure, the binding modes of the reactive...
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Function of Soils for Hum a n Societies and the Environment .The G e o l o g i c a l Society of L ppt

Function of Soils for Hum a n Societies and the Environment .The G e o l o g i c a l Society of L ppt

Ngày tải lên : 06/07/2014, 08:20
... 560-2652 E-mail bookstore@aapg.org Website http://bookstore.aapg.org India Affiliated East-West Press Private Ltd, Marketing Division, G-l/16 Ansari Road, Darya Ganj, New Delhi 110 002, India Orders: ... regard to the accuracy of the information contained in this book and cannot accept any legal responsibility for any errors or omissions that may be made The Geological Society of London 2006 All ... Indonesian Petroleum Association (IPA), the Geological Society of America (GSA), the Society for Sedimentary Geology (SEPM) and the Geologists' Association (GA) Joint marketing agreements ensure that...
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How Are We Presenting: A Look At How We All Present And Where It All Goes Wrong

How Are We Presenting: A Look At How We All Present And Where It All Goes Wrong

Ngày tải lên : 21/07/2014, 11:53
... organisation… …Makes sales as a direct result of presentations 65% Agree 27% Disagree 41% 24% 22% 5% Strongly Agree Agree Disagree Strongly Disagree 8% Unsure …Aims to develop employees presentation ... Presenter reads off screen Lack of understanding of audience's needs Lack of preparation/ practice 53% 49% 46% Tell stories, use visuals, be more human - less robot That’s all folks A huge thanks to ... software winners and losers since our 2010 survey Usage in Usage in 2010 vs 2011 2010 2011 Let’s compare usage stats between our results in 2010 and 2011 Usage in 2010 vs 2011 2010 Ppt 2007 Usage...
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Báo cáo y học: "Schizophrenia pathophysiology: are we any closer to a complete model" pps

Báo cáo y học: "Schizophrenia pathophysiology: are we any closer to a complete model" pps

Ngày tải lên : 08/08/2014, 23:21
... (WRAT3) reading tests or parental education [12] Based on this schizophrenic model, pharmacological, as well as nonpharmacological treatment methods such as education Page of (page number not for ... inheritance variation and selection of schizophrenia operates more through a Darwinian mechanism rather than a Mendelian mode of Page of (page number not for citation purposes) Annals of General ... schizophrenia Schizophrenia patients exhibit expression insufficiencies in GABA transcripts that encode GABA neurons, certain GABA (A) receptor subunits and regulators that are involved in GABA neurotransmission...
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Báo cáo y học: "The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now" potx

Báo cáo y học: "The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now" potx

Ngày tải lên : 09/08/2014, 10:23
... M, Kotake S, Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Morinaga T, Higashio K, Martin TJ, Suda T: Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism ... proteins, such as bone sialoprotein, which are released during bone damage (Table 1) Association with joint damage Landewe and colleagues have shown a significant correlation between early changes in ... different collagen fragments – such as crosslinked C-terminal and Nterminal telopeptides – are released (Table 1) Likewise, alpha chain fragments of collagenase degradation are set Available online...
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báo cáo khoa học: " Are we under-utilizing the talents of primary care personnel? A job analytic examination" ppt

báo cáo khoa học: " Are we under-utilizing the talents of primary care personnel? A job analytic examination" ppt

Ngày tải lên : 11/08/2014, 05:22
... comparisons To test the assumption that primary care work was invariant across facilities, we compared the number of tasks shared by pairs of facilities We found a high percentage of overlap among ... differences for each scale by job title and function (means and standard deviations for each scale, by function and by job title, are available in Additional file 2) Mean ratings varied significantly ... roles and functions of occupational and environmental health nurses Results of a national job analysis AAOHN Journal 2002, 50:16-25 Soh KB: Job analysis, appraisal and performance assessments of a...
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Báo cáo khoa học: "The electrocardiogram for sepsis: how close are we" doc

Báo cáo khoa học: "The electrocardiogram for sepsis: how close are we" doc

Ngày tải lên : 13/08/2014, 03:21
... finally become a clinical reality This kind of translational research has the potential to transform the care of these septic patients and to direct appropriate therapies to patients at risk early ... 329:673-682 Uzzan B, Cohen R, Nicolas P, Cucherat M, Perret G: Procalcitonin as a diagnositic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis ... their ability to discriminate bacterial versus nonbacterial causes of inflammation, and then tested a composite three-marker and sixmarker test In their study, the area under the curve was greatest...
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Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pps

Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pps

Ngày tải lên : 13/08/2014, 15:21
... bias for the outcome across trails was classified as high [15] Data analysis The trial data were tabulated and then qualitatively analyzed to determine the risk of bias, trial characteristics and ... Search strategy We searched the databases Medline, Embase, AMED, and Chinese Biomedical Database (CBM) in March 2009 The search strategy for the English language databases was an “OR” combination ... qualitative analysis Although the full text of the German language article was not available, its eligibility for inclusion was ensured according to the information in the abstract The other trials...
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Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pdf

Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pdf

Ngày tải lên : 13/08/2014, 15:21
... relational database technology is prevalent in the health care and life science domains, many of the CM databases are currently in the relational format While these relational databases serve ... local queries against the underlying relational databases DartGrid [18] is a system demonstrating the use of this semantic web approach to integrate CM databases The advantage of this approach ... that existing relational databases and applications accessing these databases need not be abandoned, while new powerful applications can be developed to make use of the Semantic Web features As...
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Connecting the dots in asia pacific how business leaders are preparing for a world where everything is connected

Connecting the dots in asia pacific how business leaders are preparing for a world where everything is connected

Ngày tải lên : 04/12/2015, 00:03
... concerns in Asia-Pacific may be attributed to a lack of awareness For instance, executives representing data-reliant sectors such as financial services (49%) and professional services (40%) are far more ... in Asia-Pacific agree that investments aimed at capitalising on the potential benefits of greater Figure 1: All change Importance of an organisation’s ability to adapt its people, processes and ... respondents are based in AsiaPacific with a majority located in India (15%), Australia (14%), China (14%), Japan (10%) and South Korea (10%)  About one-half of the survey respondents (49%) work for...
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A new vision for old age rethinking health policy for europes ageing society

A new vision for old age rethinking health policy for europes ageing society

Ngày tải lên : 06/12/2015, 23:05
... country’s healthcare system Policymakers have a dual challenge ahead: to ensure high standards of care for ageing populations, while also maintaining the financial sustainability of state health and ... healthcare 67 Administration 11 Healthcare, pharma or biotech research Strategy and policy making Healthcare, pharma or biotech manufacturing Member of an NGO, lobbying organisation or healthcare ... old age This is not to say that the European healthcare professionals we surveyed not believe that policymakers are already addressing demographic shift Around 40% say that national healthcare...
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