... which are not found in the mouse or in the rat, respectively [18] In the case ofthe S100P, B, G and Z genes, the situation is different to that ofthe S100A genes In vertebrate genomes, these genes ... indicate the predicted genes The name ofthe species and chromosome numbers are shown on the left in the cow, S100A12 in the dog and S100A2 and S100A14 in the rat (Fig and Tab II) Multiple protein ... [2] andthe comparison ofthe structures of these complexes reveals differences in the orientation ofthe three peptides and in the type of interaction patterns with S100B protein Moreover, the...
... by presenting the pulse of Src activity in the plane ofthe inactive and active fractions, si and s1 If the duration ofthe stimulus exceeds the critical value, the trajectory in the (si, s1) ... steady state of Src activity exists within two large areas that are marked by number in the plane ofthe Csk and RPTP concentrations Within these two regions of monostability, there are parameter ... transition from the Off state to On state (in the bistability domain) Regardless ofthe slope, the active Src fractions increase during the Off to On transition, whereas the value ofthe inactive...
... alignment on the same plot ofthe values found for de novo synthesis in the presence of 7.5 or 2.5 mM MnCl2 with various amounts of EDTA, or in the presence of MnCl2 only [11], as a function ofthe concentration ... where the authors have identified the reverse products and shown that the CMP activation ofthe reverse of synthesis is by a different mechanism from base exchange [20] Further analysis ofthe products ... extracted andthe amount of labelled PtdIns was determined (Table 1) In the absence of CMP, the presence of AtPIS1 allows the incorporation of labelled inositol into PtdIns, according to the enzymatic...
... receipt of persons by means of threat or use of force or other forms of coercion, of abduction, of fraud, of deception, ofthe abuse of power, or of a position of vulnerability or ofthe giving ... also like the thank all ofthe other very busy individuals who agreed to speak with us, and offer their insights based on their years of experience and expertise in the areas of physical and mental ... re-adjust their self-perception and express their devotion and dependency by continuing in the sex work demanded of them It is only later that women often begin to understand the incongruity of the...
... positions ofthe MREs within the promoter region ofthe WD geneare indicated in Fig The four MREs are located in the proximal region ofthe WD gene promoter between )434 and +114, with MREa and MREe ... response ofthe MT gene to heavy metals [10,12], the presence of MREs in the promoter ofthe WD gene suggests that MREs and their cognate binding proteins function in the regulation of WD gene expression ... the ends ofthe Ku-80 geneThe EcoRI site was used to generate the IR, andthe BamHI site was used to ligate the Ku-80 IR gene to pcDNA3.1(+) to yield pc80IR Expression ofthe Ku-80 IR gene was...
... factors The aim ofthe present study was to analyze whether a decrease ofthe angiogenic factors VEGF and bFGF and an increase ofthe angiostatic factor endostatin contribute to the impaired angiogenesis ... capacity andthe presence of teleangiectasias and other skin ulcers was found Discussion The process of angiogenesis appears to be largely impaired in SSc following the profound disarrangement ofthe ... Again, there was no association of bFGF levels with the presence of fingertip ulcers Levels of VEGF, endostatin and bFGF and other clinical parameters No correlation of VEGF, endostatin and bFGF...
... contained the boost-volume isocenter, a two dimensional (2D) reconstruction of all surgical clips, andthe marked location ofthe scar On the basis ofthe position ofthe clips andthe available ... resulted in poor coverage ofthe medio-dorsal and latero-dorsal areas ofthe breast PTVCT in the majority ofthe patients (Fig 1) Particularly the latero-dorsal areas ofthe breast PTVCT significantly ... regarded as the golden standard) For each ofthe cumulative dose plans, the total volume andthe volume outside the CT-based PTVs receiving at least 95% ofthe prescribed breast and boost doses...
... reflects the generally lower risk ofthe majority of interventions conducted in general practice, the fewer number of transfers of patients between health professionals in general practice, andthe generally ... the normal practice situation in the Netherlands The practices had a total of 72,455 patients and employed a total of 143 healthcare professionals at the time ofthe study (e.g., GPs or practice ... [12] The aim ofthe present study was to determine the prevalence and types of patient safety incidents occurring in general practice in the Netherlands Page of Table Practices included Number of...
... occurrence of AS it might not be the unique genetic factor of susceptibility Other regions ofthe PRNP or other genes could be involved either independently or in synergy and this hypothesis is ... on the genotype, the age andthe surveillance stream Considering that the animals tested from a given flock had the same distribution of age and surveillance stream as the general population, the ... increased the robustness of our results The maintenance ofthe polymorphism ofthe PRNP gene raises question This could be explained by an absence of selection due to the late onset of clinical...
... framework for the management ofthe economy at the global level abound in the wake ofthe great recession of 2007–9 It is not clear, however, whether the crisis at the end ofthe first decade ofthe twenty-first ... primarily on the policy and political consequencesofthe GFC We ask how governments responded to the challenge and what the political consequencesofthe combination ofthe GFC itself and policy ... Studies at the University of Cambridge He is the author ofThe Spectre at the Feast Wyn Grant is Professor of Politics at the University of Warwick and Vice-President for Europe and Africa ofthe International...
... less on the level of IT spending or on the technical skills ofthe IT staff and more on the degree of shared business-IT understanding the level common understanding between the IT andthe line ... investigating theconsequencesof shared understanding is based upon the resource based view ofthe firm (RBV) We believe that the development of shared understanding is rare, valuable and firm specific and ... processes and there are some areas of overlap between the different studies Specifically, each ofthe approaches includes aspects ofthe concept of IS management andthe ability to manage the business...
... both the familial occurrence of AC andthe presence of AC in patients with genetically determined cystic diseases, such as ADPKD, have indicated a genetic component in the cystogenesis of AC18 The ... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... consequently, these nine genes might be associated with the pathogenesis of temporal fossa AC Helland et al 20 found the Na+–K+–2Cl− cotransporter NKCC1 gene was escalated in AC and NKCC1 was present in the...
... craniotomy because ofthe proximity ofthe sinus to the orbit andthe anterior skull base [5] The frequency of bilateral absence ofthe frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence ofthe frontal sinus; on the right, the absence ofthe frontal sinus, and on the left, the limited aeration ofthe frontal sinus; axial ... a metopic suture, the frontal sinuses are small or absent [8-10] The form ofthe face and forehead in the presence of a metopic suture conforms to the evolutionary trend ofthe skull [30] In...
... occurrence ofthe tumor corresponded exactly one to the other; and (4) there was a more than one year interval between trauma andthe appearance ofthe tumor As regards the pathogenesis of post-traumatic ... populations are imperative because ofthe relatively low prevalence of head injuries andthe low incidence of brain tumors Conflict of Interest The authors have declared that no conflict of interest ... at the time ofthe trauma demonstrating significant injury andthe follow-up scans demonstrating tumor at the same site4 With the routine use of CT and magnetic resonance imaging (MRI), some of...
... circumstances In the resolutions ofthe VIth andthe VIIth congresses ofthe Communists Party and those ofthe important meeting ofthe National Assembly, the Government andthe Central Party ... concerning their cooperation with the Government in the financing of education and training arethe making of contributions, in which they take account of their revenue/profits andthe number and level ... mechanics and electricians After the outbreak ofthe resistance war, these schools were either moved out of towns or disbanded In order to meet the demands ofthe nation’s economy andofthe war,...
... features 60 As a rule, then, the lower the price of substitutes, the higher the quality andthe performance, andthe lower the user’s switching costs, the more intense arethe competitive pressures ... component of most management definitions of strategy Strategy is the determination ofthe basic long-term goals and objectives of an enterprises, andthe adoption of courses of action andthe allocation ... industry, andthe Ministries of Forestry and Agriculture They are also aim to turn the ministries into administrators of their assets, rather than active players in the economy Without these administrative...
... including the rationale ofthe study, the identification ofthe problem, the objectives, the scope and limitations as well as the methodology and framework ofthe study Chapter shows the literature ... most of these products are easy to produce and to be imitated At the late of 1980s, faced with the saturation sign ofthe demand for plastic householdwares andthe fierce competition in the field ... 2000 and 80% by 2005 • To improve the quality of plastic products to meet the demand of high quality consumer products ofthe country, then to increase the quantity and expand varieties of export...