applications to medicinal chemistry and drug studies

... spectrometry (ICP-OES) and atomic absorption spectrometry (AAS) for inorganic contaminants such as heavy metals, and gas chromatography (GC) and gas chromatography linked to a mass spectrometer ... investigated and shown to be contaminated, a risk assessment needs to be undertaken in order to decide what course of action to take For example, in a case where agricultural land has been found to be ... collected and sent off to a laboratory for analysis Some of these methods can be used for on-line, real time monitoring, such as sensors installed for monitoring wells or those used for monitoring

Ngày tải lên: 19/05/2017, 08:44

... Krypton 154 Kyoto 18 L Lagrangian trajectory modeling Lakes 34 257 sediments 369 119 Land contaminants 214 Land Use Planning 418 Landfilling 232 235 This page has been reformatted by Knovel to ... 180 Titanium 152 153 Toluene 134 Tin Total suspended particulate matter 42 Toxic Organic Micropollutants (TOMPS) 52 Toxicity tests 185 299 333 334 Tradeable permits Trajectories 430 28 Transfer ... of land, freshwater, or the seas, according to where they occur Similarly, pollutants discharged into a river will, unless degraded, enter the seas Solid wastes are often disposed into a landfill

Ngày tải lên: 19/05/2017, 08:44

... structure-activity studies, and to enable preparation of larger quantities of ABT-594 for advanced profiling and clinical studies Thus, a program to address this problem was initiated within the medicinal chemistry ... interacting with 5HT receptors were LSD-like and sure to share the hallucinogenic properties of LSD Instead, 5HT ligands have proven to be a rich source of new drugs as receptor subtype selective ... with serotonin (5HT) receptors If 5HT receptors had been named LSD receptors based on the actions of this exogenous ligand, then there would have been the invalid assumption that all ligands interacting

Ngày tải lên: 29/12/2017, 17:12

... heterogeneity stored in 𝛼𝑖 and 𝑤𝑖 , 𝑋𝑖𝑡 is a vector of inputs value, 𝑍𝑖𝑡 is a vector of firm-specific observed factors, 𝛽 and 𝛾 are coefficients to be estimated There are three separate factors can ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM

Ngày tải lên: 29/11/2018, 00:02

... behaviour, driving while intoxicated, and using other drugs [4] Research in this area tends to focus on the use of alcohol, tobacco, and other drugs (ATOD) triggered by both positive and negative personal ... of ATOD use because they were still too young to be vulnerable to such risks or had not demonstrated such vulnerability: P9, M,: My children are still young, and too young to talk about ATOD ... ‘attachment’ to his/her parents was perceived to be a concern, and warranted protection from ATOD use As such, these children would be less likely to initiate consumption of ATOD, and/or be less likely to

Ngày tải lên: 01/02/2020, 05:36

... heterogeneity stored in 𝛼𝑖 and 𝑤𝑖 , 𝑋𝑖𝑡 is a vector of inputs value, 𝑍𝑖𝑡 is a vector of firm-specific observed factors, 𝛽 and 𝛾 are coefficients to be estimated There are three separate factors can ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM

Ngày tải lên: 01/09/2020, 13:55

... heterogeneity stored in 𝛼𝑖 and 𝑤𝑖 , 𝑋𝑖𝑡 is a vector of inputs value, 𝑍𝑖𝑡 is a vector of firm-specific observed factors, 𝛽 and 𝛾 are coefficients to be estimated There are three separate factors can ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM

Ngày tải lên: 17/09/2020, 08:25

... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... data The stochastic approach, called Stochastic Frontier Analysis (SFA), was mentioned first in Aigner, Lovell, and Schmidt (1977) and Meeusen and Broeck (1977) This method, contrary to DEA, requires

Ngày tải lên: 10/10/2020, 11:15

... heterogeneity stored in 𝛼𝑖 and 𝑤𝑖 , 𝑋𝑖𝑡 is a vector of inputs value, 𝑍𝑖𝑡 is a vector of firm-specific observed factors, 𝛽 and 𝛾 are coefficients to be estimated There are three separate factors can ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM

Ngày tải lên: 31/12/2020, 10:28

... Estimates and Applications to Uniqueness and Control Theory Ferrucio Colombini and Claude Zuily, editors PNLDE 47 Advances in the Theory of Shock Waves Heinrich Freistühler and Anders Szepessy, editors ... Colombini, and D DelSanto, editors PNLDE 70 Vortices in the Magnetic Ginzburg–Landau Model E Sandier and S Serfaty PNLDE 71 Fuchsian Reduction: Applications to Geometry, Cosmology and Mathematical ... Quasi-hydrodynamic Semiconductor Equations Ansgar Jüngel PNLDE 42 Semigroups of Operators: Theory and Applications A.V Balakrishnan, editor PNLDE 43 Nonlinear Analysis and its Applications to Differential

Ngày tải lên: 01/06/2022, 08:42

... heterogeneity stored in 𝛼𝑖 and 𝑤𝑖 , 𝑋𝑖𝑡 is a vector of inputs value, 𝑍𝑖𝑡 is a vector of firm-specific observed factors, 𝛽 and 𝛾 are coefficients to be estimated There are three separate factors can ... from the model in Battese and Coelli (1988) The random effects models in Pitt and Lee (1981), Battese and Coelli (1988) and Schmidt and Sickles (1984) (column [2], [3] and [4]) gives similar results ... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM

Ngày tải lên: 17/07/2022, 09:18

... OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS STOCHASTIC FRONTIER MODELS REVIEW WITH APPLICATIONS TO VIETNAMESE SMALL AND MEDIUM ... important role in the economy due to the high demand of metal products, especially steel and iron in daily life, production and, mostly construction To help maintain and develop the benefit from this ... data The stochastic approach, called Stochastic Frontier Analysis (SFA), was mentioned first in Aigner, Lovell, and Schmidt (1977) and Meeusen and Broeck (1977) This method, contrary to DEA, requires

Ngày tải lên: 01/10/2022, 00:03

... Brdaric and Kristina Gopcevic Chapter 14 Peptides and Peptidomimetics in Medicinal Chemistry Paolo Ruzza Chapter 15 Carbonic Anhydrase Inhibitors and Activators: Small Organic Molecules as Drugs and ... considered to be deleterious to the color quality and flavor, and loss of nutritional and market values of foods So, it causes the enzymatic * Corresponding Author Medicinal Chemistry and Drug Design ... compliance, drug resistance, low efficacy, and poor safety Since the evolution of drug resistance is likely to compromise every drug over time, the demand for new drugs and targets is continuous The drug...

Ngày tải lên: 27/06/2014, 00:20

... Brdaric and Kristina Gopcevic Chapter 14 Peptides and Peptidomimetics in Medicinal Chemistry Paolo Ruzza Chapter 15 Carbonic Anhydrase Inhibitors and Activators: Small Organic Molecules as Drugs and ... considered to be deleterious to the color quality and flavor, and loss of nutritional and market values of foods So, it causes the enzymatic * Corresponding Author Medicinal Chemistry and Drug Design ... compliance, drug resistance, low efficacy, and poor safety Since the evolution of drug resistance is likely to compromise every drug over time, the demand for new drugs and targets is continuous The drug...

Ngày tải lên: 02/12/2016, 12:49

... cells and lack of selectivity and damage of healthy tissues Drug delivery systems are aimed to minimise the drug degradation, to increase its bioavailability, to target it to specific cells and to ... must be achieved prior to functionalisation and construction of nanodevices In order to be used in biology and medicinal chemistry, carbon nanotubes need to be purified and soluble in physiological ... Moreover, drug delivery based on carbon nanomaterials has been illustrated Few chapters are dedicated to toxicity and to the use of nanomaterials as pollutant probes The debate on fullerene and CNT toxicity...

Ngày tải lên: 17/02/2014, 05:20

... refers to two topics, namely, Computational Medicinal Chemistry and Drug Design It unites these topics by giving an overview of the main methods at the disposal of the computational chemist and to ... and to highlight some applications of these methods in drug design Although drug and ligand appear to be synonymous in this volume, they most denitely are not Notwithstanding drug design in the ... molecular and solid-state systems in chemistry, biochemistry, biology, and pharmaceutics The development of new semiempirical methods and their improvement and extension of application to larger and...

Ngày tải lên: 12/05/2014, 17:28

... Algebra and Its Applications, vol 416, no 2-3, pp 336–347, 2006 [8] H Pickmann, J Ega˜ a, and R L Soto, “Extremal inverse n eigenvalue problem for bordered diagonal matrices,” Linear Algebra and ... diagonal matrices,” Linear Algebra and Its Applications, vol 427, no 2-3, pp 256–271, 2007 [9] H T Kung and B W Suter, “A Hub matrix theory and applications to wireless communications,” EURASIP Journal ... elements to be ordered so that d1 < d2 < · · · < dm−1 Furthermore, we may assume that all To apply Theorem for estimating eigenvalues of an irreducible arrowhead matrix Q, we need to decompose Q into...

Ngày tải lên: 21/06/2014, 20:20

... one subband corruption (affecting subbands 2, 3, and 4, resp.), three cases with two subband corruption (affecting subbands and 3, and 4, and and 5, resp.), and two cases with three subband corruption ... and conditional union model (CU), in stationary bandselective noise with 1-subband, 2-subband, and 3-subband corruption within subbands modeled by 10 feature streams (5 static and delta subband ... frame-by-frame basis and can be applied to a single-state HMM or GMM The model is defined in (13) and (14), and uses subband features to model speech subject to unknown, time-varying band-selective corruption...

Ngày tải lên: 22/06/2014, 23:20

... current one: its Up and Left neighbors, its spatial parent, aunts, and cousins, and its spatiotemporal parent together with its Up and Left neighbors and spatiotemporal aunts In order to check the validity ... optimal predictor is proved to be superior to the reconstruction performed with the details corresponding to the lost subbands set to zero We also notice that, as expected, the loss of a subband at ... itive, we need to constrain the weights to be positive As we can notice from this table, the EC with β = proves to be the most robust and of the best performance compared to the LS and ML criteria...

Ngày tải lên: 23/06/2014, 01:20

... Jayalaxmi and sister Dr Spandan for being understanding, tolerant and supportive through my long post-graduate stint through a Masters and now a PhD degree To my dear wife Yamuna, I am more complete and ... as YouTube and billions of images on repositories such as Flickr or Picasa It becomes useful and necessary to automate the process of understanding such content and enable subsequent applications ... holistic way to look at problems relating to image and video understanding than to try and understand visual content alone in isolation A growing body of research is correlating human understanding...

Ngày tải lên: 09/09/2015, 18:49