... x(t1 ) = sin(2πt1 ) + sin(2π3t1 ) + sin(2π5t1 ) x(t2 ) = sin(2πt2 ) + sin(2π3t2 ) + sin(2π5t2 ) x(t3 ) = sin(2πt3 ) + sin(2π3t3 ) + sin(2π5t3 ) x(t4 ) = sin(2πt4 ) + sin(2π3t4 ) + sin(2π5t4 ) ... written in matrix form as sin(2πt1 ) sin(2π3t1 ) x(t1 ) x(t2 ) sin(2πt2 ) sin(2π3t2 ) = x(t3 ) sin(2πt3 ) sin(2π3t3 ) x(t4 ) sin(2πt4 ) sin(2π3t4 ) sin(2π5t1 ) sin(2π5t2 ... practical applications in the form of projects that can be done using material presented in the first 10 chapters In Chapter 11, concepts in adaptive filtering are introduced, and simple projects in system...
Ngày tải lên: 18/10/2015, 20:05
... protein-tyrosine kinases in vivo and in vitro Cell 57, 1109–1122 18 Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK & Wong AJ (1996) A Grb2-associated docking protein in EGF- and insulin-receptor ... MAP kinase signaling pathway TAM67 retains the DNA binding and leucine-zipper region of c-Jun, but it lacks the transactivation domain of c-Jun (amino acids 1–122) It thus blocks the binding of ... through the MAP kinase cascade [49] Our study showed that EGF caused a substantial increase in AP1 DNA binding In addition, this increase was prevented by MAP kinase kinase inhibitor PD98059...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Transcription of individual tRNA1Gly genes from within a multigene family is regulated by transcription factor TFIIIB pdf
... allow TFIIIB binding in an active state (i.e capable of interacting with TFIIIC to Gly stabilize binding) in the case of tRNA1 -1 and in an inactive state (incapable of efficient interaction with ... TFIIIB-containing fraction (0.3 m KCl eluate from heparin–Sepharose) was predicted to bind to the probe As a positive control TBP binding to this element was also included in the binding assays ... via interactions with TFIIIC The stable binding (heparinresistant complex formation) also required the presence 5196 of TFIIIC (Fig 3A) Independent binding of TFIIIB was again confirmed using...
Ngày tải lên: 20/02/2014, 02:21
Báo cáo hóa học: " Updated survivals and prognostic factor analysis in myeloma treated by a staged approach use of bortezomib/thalidomide/dexamethasone in transplant eligible patients" pot
... institution review board in accordance with the Declaration of Helsinki, and informed consent was obtained from all participating patients The treatment algorithm was shown in Figure Monitoring ... analyzed on an intention-to-treat basis Progression was defined as ≥25% paraprotein increase in two consecutive tests four weeks apart Relapse was defined as reappearance of the paraprotein on immunofixation ... OS, including methylation of Death-associated Protein Kinase (DAPK) and the development of oligoclonal reconstitution, were analysed Methods Treatment The study started in early 2005 and ended in...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
... receptor type 1-related protein y, IgG1-linked murine recombinant fusion protein; MBP, mannose-binding protein; rVCP, recombinant Vaccinia virus complement control protein; sCR1, soluble complement ... (in 0.1% milk in PBS containing 0.05% TWEEN) and murine recombinant mouse C5a at defined concentrations for establishing the standard curve After incubation and subsequent washing steps, biotinylated ... represents an approach with potential clinical implications In order to induce a continuing complement inhibition during the acute inflammatory phase in the first days, injections were repeated at 24...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "The NFI-Regulome Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors" pdf
... sequences input by either typing or cutting and pasting (Figure 3C, arrow 4, BLAT) Binding site displays Binding sites for TFs can be displayed in a number of ways Selecting and submitting a TF ... NFI-regulated genes is input by trained Gene Annotators The papers are read and a listing of all TF binding sites, transcription start sites and other relevant information including the binding site locations ... Clinical Bioinformatics 2011, 1:4 http://www.jclinbioinformatics.com/content/1/1/4 Page of 10 Figure Graph View of genes containing AP-4 binding sites, aligned by ATG as The height of the bar indicates...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Temporal and spatial patterning of an organ by a single transcription factor" pps
... for many genes the binding affinity of PHA-4 for its promoter element could determine the timing of expression: genes with high-affinity binding sites were expressed earlier in development and ... genes with low-affinity binding sites were expressed later in development These two modes of transcriptional regulation, differences in PHA-4 binding-site affinity and combinatorial activation ... V: The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN14 protein synthesis after the initiation of translation Dev Biol 1999, 216:671-680 Reinhart...
Ngày tải lên: 14/08/2014, 14:21
Intravesical tumor necrosis factor alpha gene therapy mediated by a novel liposome system in an orthotopic murine bladder cancer model
... agents in the treatment of bladder cancer include Bacillus Calmette-Guerin (BCG), thiotepa, mitomycin, doxorubicin, valrubicin, interferon, interleukin-2, keyhole limpet haemocyanin, bropirimine ... viruses were effective at infecting, replicating within, and achieving subsequent cell lysis for bladder cancer cells both in vitro and in vivo with a single intravesical instillation (Cozzi et ... cytokine gene therapy In recent years, several cytokine genes have been tested as candidates for cytokine gene therapy in bladder cancer such as interleukin-2, interferon-β and interleukin 12...
Ngày tải lên: 08/11/2015, 16:45
Báo cáo y học: "Spontaneous Hemoperitoneum Caused By a Diverticulum of the Sigmoid Colon"
... the blood supply to the intestine In the present case, blood supply to the intestine had to be preserved because the patient had hemoperitoneum In addition, the remaining colon wall was normal, ... Int J Med Sci 2011, copy owing to incomplete bowel preparation The bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of the diverticulum ... poor The invagination of diverticulum has an advantage over diverticulectomy in that it minimizes bowel leakage [15] Moreover, invagination of diverticulum can be easily performed using laparoscopy...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Cell Cycle Arrest by a Natural Product via G2/M Checkpoint"
... [1] In addition, genistein is found to induce G2/M cell cycle arrest in MCF-7 cells [2] Whereas anti-carcinogenic compounds like lunasin and lectins in soybean were shown to induce apoptosis in ... controlling the entry of cells into mitosis by maintaining the G2/M checkpoint [22] Other researchers had also found that over-expression of 14-3-3σ in breast cancer cell lines was able to inhibit ... Annexin V-FITC Annexin V-FITC 5.8 PI PI PI PI 4hr 11.7 6.1 Annexin V-FITC Annexin V-FITC 0.8 Annexin V-FITC Annexin V-FITC 4.1 Annexin V-FITC PI PI PI PI 6hr 5.1 10.8 Annexin V-FITC Annexin V-FITC...
Ngày tải lên: 02/11/2012, 11:12
Treatment of Textile Wastewater by a Coupling of Activated Sludge Process with Membrane Separation
... would be difficult to maintain a high flux Thus, in the following experiments, the backflushing condition was determined first before proceeding to the main experiments In this experiment, the ... effect of time interval between backflushes on flux The flux seemed to be stable when the backflushing interval was 1.5 minutes The increase in backflush interval caused reduction in the flux However, ... The optimum condition of for backflushing technique was obtained at 1.6 bar pressure applied for second at 1.5-minute interval minute 1.5 minutes minutes 2.5 minutes P 1.2 bar P 1.6 bar P bar 25...
Ngày tải lên: 05/09/2013, 09:08
DMF Decomposition and Nitrogen Removal Performance by a Mesh-Filtration Bioreactor under Acidic Conditions
... decarbonylation In the former pathway, dimethylamine and methylamine, which are produced as intermediate compounds, are toxic to biomass; this may account for the difficulties in treating wastewater ... a mesh- filtration unit instead of a membrane) was able to maintain biomass at a very high concentration In this process, stable filtration performance was obtained by intermittent filtration ... suggesting that acidophilic heterotrophic and nitrifying bacteria had become acclimated in the reactor Characterization of the unique bacteria in the reactor remains a subject for future investigation...
Ngày tải lên: 05/09/2013, 09:38
Inactivation of microorganisms in untreated water by a continuous flow system with supercritical CO2 bubbling
... method for inactivating microorganisms in drinking water In addition, we aim to investigate the effect of the SC-CO2 treatment with regard to structural damage and enzyme inactivation in E coli ... stage in the SC-CO2 treatment and the inactivation rate increased as the temperature increased The survival curves described by a rapid-to-slow two stage kinetics were in agreement with the findings ... untreated water is shown in Figure The coliform bacterial count in the untreated water decreased almost linearly with increasing CO2/sample flow rate in the SC-CO2 treatment In particular, coliform...
Ngày tải lên: 05/09/2013, 09:38
Divided by a Common Language
... lanes in which a pneumatic cylinder whisks your checks (spelled cheques in Britain), papers, and money into the bank (although too many coins in the cylinder can produce a rather interesting effect ... pudding with currants in it steak and kidney pudding chopped steak and kidney steamed in a pudding basin (bowl) lined with pastry summer pudding bread and fresh fruit allowed to set in a pudding ... origin, like honor or hour, in which the h is silent The h was reintroduced in pronunciation in the UK during the nineteenth century under the influence of the spelling of the word Differences in...
Ngày tải lên: 08/12/2013, 11:59
Tài liệu Central bank governance and financial stability: A report by a Study Group doc
... “Maintain financial stability” is less easily interpreted than “maintain price stability” since price stability can be numerically approximated in terms of a generally agreed index, whereas financial ... somewhat in practice during the crisis In the case of the Bank of England, decision-making on emergency lending was (and remains) the province of the Chancellor Analysis and advice leading into such ... taking a leading role in resolution and others being less closely involved In Japan, where emergency powers are available to the authorities, the Bank of Japan is involved in decision-making...
Ngày tải lên: 16/02/2014, 10:20
Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
... proliferation, eliminating any possible effects as a result of the introduction of DNA within cells, and indicating that, in itself, the interaction of ODN with STAT3 induced these effects (i.e inhibition ... distinct functions in cells STAT3 is mostly involved in cell survival and proliferation, and STAT1 is involved in anti-viral and immune defence and cell death, in response to interferons, including ... nuclear protein extracts were incubated for 30 at °C in binding buffer (1% NP40, 50 mm Hepes, pH 7.6, 140 mm NaCl) containing salmon sperm DNA (1 lg per assay) and lg of biotinylated hairpin decoy...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Alice Cogswell Bemis A Sketch by a Friend pdf
... a charming glimpse into the first meeting between Mr and Mrs Bemis in some interesting reminiscences Mr Bemis has recently written for his grandchildren He had been settled in business in St Louis ... calling one evening and presenting the letter As I am writing these lines I can see 'Miss Cogswell' coming into the parlor where I was awaiting her She was dressed in the fashion of the day, having ... enjoyed watching their sports and their life in the open Her windows overlooked the lake, and she sat there hour after hour watching the parties coming and going in boats and climbing the hills...
Ngày tải lên: 18/02/2014, 09:20
Tài liệu Báo cáo khoa học: PC1⁄3, PC2 and PC5⁄6A are targeted to dense core secretory granules by a common mechanism doc
... catalytic domain comprising the catalytic triad of amino acids aspartic acid, histidine and serine, and a stabilizing P-domain involved in the binding of Ca2+ [1] The C-terminal domains of the PC ... demonstrated that both of the fusion proteins containing C-terminal deletions show reduced sorting efficiency as compared to protein containing the intact 38 amino acid domain (Fig 2B,C, compare 878–906 and ... granule-sorting signal in this domain In the current study, we sought to define the secretory sorting signals in the PC5 ⁄ 6A C-terminus and to compare these to the granule-sorting domains in the other...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Orthodontists and patient´s aesthetic perception to different types of profi les modifi ed by a computer program pdf
... surgeons are involved in treatments affecting facial profile Therefore, their perception of facial esthetics bears in uence in treatment planning Nevertheless, many surgical plans are visualized in the ... esthetic profile This information can ease information among clinicians and patients Previous methods used to analyze an attractive facial profile include the following: line tracing, silhouettes, ... for Latin specialists training might in uence their perceptions? Is culture shock affecting perception of profile attractiveness as has been shown by other studies? It would be interesting to...
Ngày tải lên: 19/02/2014, 17:20