application to spatially disconnected domains in membranes

... These phases include the following activities: defining public concern, determining multiple issues, defining measurable indicators, and interpreting information on measured indicators to derive ... above investigation, integration is tentatively interpreted as an act or a process of joining or combining something with something else The integrated approach is a way of perceiving and solving ... feedback leads to divergent behaviour: indefinite expansion or explosion (a running away toward infinity) or total blocking of activities (a running away toward zero) Each plus involves another...

Ngày tải lên: 06/11/2012, 10:35

Ngày tải lên: 05/03/2014, 16:20

... reaction products (appearing in the nominator) and/or vanishing concentrations of the reaction substrates (appearing in the denominator), the concentration-dependent term in Eqn (5) may assume arbitrarily ... The remaining four reactions, displaying differing flux rates, belong to a segment of the reaction network comprising redundant routes This discrepancy points to another problem inherent in the ... maximal biomass production at a given total flux is obviously equivalent to maintaining a given rate of biomass production at a minimum of the total flux Insofar, the principle of maximal biomass production...

Ngày tải lên: 07/03/2014, 15:20

... determining the beginnings of clauses is difficult in a single process because all features mentioned above are local information Therefore, the global information is also used to detect the beginning ... on quotations and inserted clauses to text formatting, such as text summarization References Taku Kudo and Yuji Matsumoto 2001 Chunking with support vector machines In Proceedings of the NAACL ... of 188 talks in the CSJ, which contain 6,255 quotations and 818 inserted clauses We used 20 talks for testing The test data included 643 quotations and 76 inserted clauses For training, we used...

Ngày tải lên: 23/03/2014, 18:20

... continued to increase in the ‘Landes de Gascogne’ during 1988–1998 Final harvest The simulated volume harvested in the final cuts exhibited an increasing trend with time; the cuts raised up to to ... the region included in this study, the final total volume was 118 Mm3 for SII and 124 Mm3 for SI (figure 9) Despite the increasing intensity of final cuts and thinnings, the simulations indicated ... Thinnings The intensity of thinnings increased by at least 50% during this period Nevertheless, the wood continued to accumulate during this period SI scenario was more regular than SII and finally...

Ngày tải lên: 08/08/2014, 14:21

... These phases include the following activities: defining public concern, determining multiple issues, defining measurable indicators, and interpreting information on measured indicators to derive ... above investigation, integration is tentatively interpreted as an act or a process of joining or combining something with something else The integrated approach is a way of perceiving and solving ... feedback leads to divergent behaviour: indefinite expansion or explosion (a running away toward infinity) or total blocking of activities (a running away toward zero) Each plus involves another...

Ngày tải lên: 10/08/2014, 01:22

... (training and testing) were constructed The testing set included offspring from sires with records in the training set Sires included in the testing set were required to have sires in the training ... sibs) in the training set ranged between and 284, with the mean and median being 32 and 17, respectively Sixty-one sires (15.5% of the total) were included in the testing set, whereas the remaining ... sires in the training set Further, an additional "middle" class (FCR between percentiles 0.40 and 0.60) was included to enrich the discretized data In total, information gain was calculated in ten...

Ngày tải lên: 14/08/2014, 13:21

... vector whose i-th entry is |xi |, x↓ ∈ IRn be the vector of entries of x being arranged in the non-increasing order x↓ ≥ · · · ≥ x↓ , and x↑ ∈ IRn be the vector of entries of x being arranged in ... humanities, ranging from computational biology and biomedical studies to data mining, financial engineering and risk management For a comprehensive overview, one may refer to [52] In order to make the ... The remaining parts of this thesis are organized as follows In Chapter 2, we introduce some preliminaries that are fundamental in the subsequent discussions, especially including a brief introduction...

Ngày tải lên: 09/09/2015, 11:08

... hemolysed in H2O in the presence of protease inhibitors (0.19 mM leupeptin, 0.17 mM chymostatin, mM N-p-tosylL-lysine chloromethyl ketone (TLCK), mM N-p-tosylL-phenylalanine chloromethyl ketone (TPCK), ... moieties in b-anomeric configuration [22] The remaining 35% of incorporated [3H]GlcN that is resistant to the Jack Bean hexosaminidase could be either GPI-linked, N-linked to asparagines or linked to ... containing the appropriate protein was cut and subjected to exogalactosylation Cut nitrocellulose pieces corresponding to the 195 (whole MSP-1), 56 (C-terminal) and 86 (N-terminal) kDa MSP1 proteins...

Ngày tải lên: 08/03/2014, 08:20

... conformation This invariable folding of Gln5 is related to the helix initiator propensity of Pro4 and decreases from Gln5 to Gly9 In methanol, the helical structures in the 4–8 domain increase with ... than SP (Table 1) Regarding the minor binding site NK-1m, SP and [Pro9]SP show a 10-fold increase in affinity compared to their affinity for the NK-1M binding site, with Ki in the subnanomolar range ... Chassaing, G (2001) Ca methylation in molecular recognition: application to substance P and the two neurokinin-1 receptor binding sites Eur J Biochem 268, 2997–3005 Wuthrich, K (1986) NMR of Proteins...

Ngày tải lên: 08/03/2014, 08:20

... subunit binding domains (Eur J Biochem 269) 547 A subunit binding domains In this study, we used the B56a isoform as a model regulatory protein to identify structural elements involved in the interaction ... from amino acids 325±383 was capable of independently binding to GST-A (Fig 2) These regions were named A subunit binding domains (ASBD) and Given that the two distinct regions can bind to the ... evolved from a single ancestral B subunit In summary, in this study we have de®ned two separate PP2A binding domains in the regulatory and targeting B56a subunit, which are conserved in sequence...

Ngày tải lên: 08/03/2014, 10:20

... determined from data obtained by changing the concentration of the linking intermediate and measuring the corresponding rates of the modules (i.e from module rates versus S data) Changes in the intermediate ... an effector would have to operate in order to produce a large change in a particular metabolic concentration or flux This is relevant for studying where a physiological activator or inhibitor would ... to obtain any value of ri manipulating the parameters in module i However, some ri values would result in unrealistic values of the concentration of the linking intermediate (S), e.g either too...

Ngày tải lên: 14/03/2014, 23:20

... coefficients (BAC, defined as the total element concentration in shoots with respect to total element concentration in soil, both in mg kg(1) and accumulation factors (AF, defined as the total element ... pollutant-accumulating plants which are able to extract and translocate pollutants to the harvestable parts Phytoextraction can be divided in continuous phytoextraction (using hyperaccumulator plants) and induced ... largely influenced by the form and speciation of As AsIII is more mobile and more toxic than AsV Gaseous arsines are most toxic whereas arsenobetaine and arsenocholine (mainly found in marine organisms)...

Ngày tải lên: 15/03/2014, 23:49

... (creatine binding pocket, residues 60–72 in 648 Torpedo) is nearly identical in all five CK domains, and the nucleotide binding loop (323–335 in Torpedo) is quite similar (shown in blue in Fig ... catalytic residues identified in Torpedo CK are conserved in all three FlgCK domains (shown in red in Fig 1), as is the ‘hinge’ proline (position 21 in Torpedo, show in pink in Fig 1) Based on the above ... ligated into TOPO cloning vectors and mutated The mutated construct was then excised and re-ligated back into the original expression vector containing the two non-mutated domains The following restriction...

Ngày tải lên: 16/03/2014, 06:20

... cholesterol and sphingolipids to organize an ordered lipid phase, including some proteins such as caveolin, glycosylphosphatidylinositol-anchored proteins, and tyrosine kinases Mainly due to their ordered ... and sphingolipids, which are present in cell membranes [31] Several proteins are preferentially distributed to these microdomains, including glycosylphosphatidylinositolanchored protein, the ... contains a basolateral sorting signal in its intracellular loop region [30], whereas the C-terminal tail of Glut3 contains a targeting motif directing the trafficking of basolateral-sorting Glut1 to...

Ngày tải lên: 23/03/2014, 09:20

... the index of the source (resp target) string generated up to the ith edit operation; and f ins ,f del ,and f sub are functions mapping to [0, 1].2 Context independence is not to be taken here to ... that needs to be generated at step i in order for the total yield, v(z1 ), to equal the string pair The RY stochastic model is similar to the one introduced earlier by Bahl and Jelinek (1975) ... a1 ; otherwise a2 is incremented by to point to the next symbol in the source string The end RV is an indicator of when we are past the end of both source and target strings (a > m and b > n)...

Ngày tải lên: 23/03/2014, 19:20

... strings may contain an exponential number of elements with respect to the length of those strings, building such an automaton may face combinatorial problems Our solution simply consists in randomly ... Second, analyzing the segmentation induced by analogical learning would be interesting Third, we need to address the problem of combining the translations produced by analogy into a front-end ... end -to- end discriminative approach to machine translation In 21st COLING and 44th ACL, pages 761–768, Sydney, Australia E Morin, B Daille, K Takeuchi, and K Kageura 2007 Bilingual terminology mining...

Ngày tải lên: 31/03/2014, 20:20

... expansion in loan provision, especially in consumer financing, growth in the share of foreign assets in the banking sector as well as an increase in pubic trust in the financial system These factors ... Commonwealth of Independent States TE Transition Economies Measuring Efficiency and Explaining Failures in Banking: Application to the Russian Banking Sector Introduction Banking system plays ... significant share of financing to mining Central (excluding Moscow), North West and Volga regions prevail in issuing credit to manufacturing, since these regions host most of the large industrial enterprises...

Ngày tải lên: 03/06/2014, 02:06

... 1) divided into eight scales: physical functioning (PF1 to PF10), role limitations relating to physical health (RP1 to RP4), bodily pain (BP1 and BP2), general health perceptions (GH1 to GH5), ... missingness in the SF-36 questionnaire; we also used the classification proposed by Little and Rubin to characterize missing data processes operating during administration of this questionnaire In ... problem in clinical trials of cancer therapy? Statistics in Medicine 1998, 17:667-677 Fayers PM, Curran D, Machin D: Incomplete quality of life data in randomized trials: missing items Statistics in...

Ngày tải lên: 18/06/2014, 19:20

... symptom domains Flow diagram of 28 symptom domains in questionnaire and criteria for determining frequent and responsive symptom domains Sixteen symptom domains were included from commonly used indices ... analysis of symptom domains Cluster Cluster analysis of symptom domains Using single clustering, a dendrogram of the 28 symptom domains is presented to illustrate the likely redundancy in some items, ... responsive symptom domain (frequently present and responsive to change) Infrequent or unresponsive symptom domains Fifteen of the 28 symptom domains did not fulfill the criteria These symptom domains are...

Ngày tải lên: 18/06/2014, 19:20