... calculation of k+ We have tested the application of the uorescent analogue CBC as a tool for investigation of the binding kinetics of nonuorescent ligands Cyano-cobalamin (CNCbl) was examined in the ... indicated at least a 10-fold faster liberation of the uorescent analogue when compared with Cbl The CBC dissociation spanned at least 90% of the total amplitude, which allows one to describe the ... transition in the absorbance spectra of the protein-associated ligands IFH2OCbl IFCNCbl As seen from the data in Fig 5C, stability of both IF30CblIF20 and IF30CBCIF20 was lower than that of the...
Ngày tải lên: 19/02/2014, 05:20
... a THE HASSE PRINCIPLE FOR PAIRS OF DIAGONAL CUBIC FORMS 869 statement, then we are implicitly asserting that for each ε > the statement holds for sufficiently large values of the main parameter ... small in the context of Theorems and and the associated auxiliary mean value estimates, and so small that one has also η < θj < (1 ≤ j ≤ s) In this way, we may suppose that the solution θ of the ... is often the case with applications of the circle method, it is desirable to have available a sharp upper bound bought with additional generating functions We begin with an auxiliary lemma analogous...
Ngày tải lên: 22/03/2014, 20:21
Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... 10.1186/1479-5876-8-51 Cite this article as: Arai et al., Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R ... were among the "inventoried" assays available from ABI, and are described in Table cDNA synthesis, preparation of samples for TLDA assay and measurements of RNA concentration were performed as ... housed and cared for according to the American Association for Accreditation of Laboratory Animal Care guidelines The Wyeth Institutional Animal Arai et al Journal of Translational Medicine 2010,...
Ngày tải lên: 18/06/2014, 16:20
báo cáo sinh học:" Forecasting the need for medical specialists in Spain: application of a system dynamics model" potx
... are those used by the US Department of Health and Human Services [51] These rates and appropriate standards can be set as parameters, as the model is an instrument that allows Page of the Health ... the analysis of the degree of sensitivity of the parameters that are most uncertain: population growth (with scenarios for rapid, moderate, and slow), and the growth rate for the demand of each ... liberal immigration policies, it had the highest population growth rate of the European Union, with an average annual increase of 1.6% and a Page of total increase of 15%, leading to a great increase...
Ngày tải lên: 18/06/2014, 17:20
Báo cáo khoa học: "Interpreting the variations in xylem sap flux density within the trunk of maritime pine (Pinus pinaster Ait.): application of a model for calculating water flows at tree and stand levels" pdf
... was calculated on a leaf area basis by: = where A is the cross-sectional area of the conc ductive pathway and L the leaf area (all sided) of the tree A was measured after the experic ment on the ... shape, and calculating the sap flux as the average of the measurements made at a height of m on a sample of ten trees at Carrasqueira and at a height of 8.5 m on seven We trees at the Bray site The ... temperature and transpi- a crown ration rate; the resistance and capacitance of each compartment are independent of the flux or water potential of the compartment and remain constant during the day...
Ngày tải lên: 09/08/2014, 04:20
Adaptation and application of a state of the art impedance analyzer for characterization of silicon p i n diodes
... response AC signal of the sample and the standard circuit The software controls the AC amplitude and DC bias of the signal passed to the standard circuit and the sample, and receives signal from standard ... relationship between the phase angle of impedance and the product of the resistance, the capacitance, and the frequency of measurement As a result, the phase angle of a sample is determined by the ... constant The magnitude of this dipole relaxation time constant is equal to the product of the resistance and the capacitance of the material The presence of an ideal non-polar dielectric layer,...
Ngày tải lên: 26/09/2015, 10:59
báo cáo hóa học: " Application of a hybrid wavelet feature selection method in the design of a self-paced brain interface system" pptx
... signal or the output of an actual switch Such signals can be used to label the brain signals and to evaluate the performance of a BI The data analysis of individuals with motor disabilities was ... event-related potentials by means of fast wavelet transform Brain Lang 1999, 66:129-145 Samar VJ, Bopardikar A, Rao R, Swartz K: Wavelet analysis of neuroelectric waveforms: A conceptual tutorial Brain ... AB2 Figure Spatial distribution of the average number of selected features for Subject AB2 ther decrease the number of channels used for the operation of the system This approach would rank the...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: " Application of a MANET Testbed for horizontal and vertical scenarios: performance evaluation using delay and jitter metrics" potx
... designed and implemented the testbed, including scenarios and data gathering EK participated in the data analysis and theoritical contents of the paper TO implemented the graphical user interface for ... the plot, the bottom and top of the box are always 25th and 75th percentile, respectively, and the band near the middle of the box is always the median The end of the whiskers can represent the ... open areas of our fifth floor, while in the horizontal obstacle scenarios the nodes are placed inside rooms to analyze the effect of obstacles (walls) In Figure 1 (a) , Page of 14 Hiyama et al Human-centric...
Ngày tải lên: 21/06/2014, 06:20
Báo cáo lâm nghiệp: " from the simple application of a mixture of to more gibberellins integrated explanations" pot
... demonstrated that after its exogenous application female flowering was stimulated (imbault et al., 1988) Abscisic acid In the same experiment, Pilate (1987) observed an increase of abscisic acid (ABA) ... in the shoots just after stem girdling and at the end of the flooding treatment Flooding had an especially dramatic and long lasting effect, since 73 days after treatment the levels of ACC and ... quantifying GAs by enzymelinked irnmunosorbent assay (Fl. 5A) , effect of the treatments which create a rapid polar GAs Recently, using immunological analysis instead of bioassays, Doumas et al., (1989)...
Ngày tải lên: 09/08/2014, 04:20
Báo cáo khoa hoc:" Application of a biotin functionalized QD assay for determining available binding sites on electrospun nanofiber membrane" pdf
... that provides the greatest number of available antibody attachment sites for assay development Increasing the quantity of nanofibers per square cm will increase the surface area of the mat and ... fluorescence signal that is a fundamental aspect of quantum dots has the promise to allow for measurement of small changes in the amount of these particles in solution or attached to a planar surface More ... that allowed for the determination of available ligand binding sites of avidin chemically attached to surfaces The assay lost its linearity when the thickness of the electrospun nanofiber mat...
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: " The Scandinavian Solutions for Wellness study - a two-arm observational study on the effectiveness of lifestyle intervention on subjective well-being and weight among persons with psychiatric disorders" pot
... of persons with schizophrenia [30], and also because this scale was already part of the SfW program in Scandinavia and the feedback from the SfW instructors about the ability of the participants ... was defined as a change between - cm and cm, and an increase was defined as cm increase or more For weight a decrease was defined as a loss of at least kg, stable weight was a Page of 12 change ... to play any role here The choice of the short-form of the SWN scale in this study was governed by the history of the scale as it was developed and validated in a clinical trial measuring the subjective...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo khoa học: "Application of a zona pellucida binding assay (ZBA) in the domestic cat benefits from the use of in vitro matured oocytes" pptx
... in the design of the study UH and EA collected the samples, and UH performed the ZBAs UH drafted the manuscript EA and BSH participated in the coordination of the study and helped to draft the ... vitro matured counterparts With FT spermatozoa tested on FT ZP, there was no sperm-zona binding at all This may partly be due to changes in the capacity of spermatozoa to maintain a normal plasma ... Small Animal Medicine and Surgery at SLU for providing cat testes/epididymides, the Gammelstad Animal Hospital and the Sundsvall Small Animal Clinic for collecting and freezing ovaries, and the...
Ngày tải lên: 12/08/2014, 18:22
Báo cáo thú y: "Application of a pig ligated intestinal loop model for early Lawsonia intracellularis infection" doc
... indicating an importance of intestinal microenvironment on the bacteria Also the bypassing of the stomach may have influenced the pathogenic potential of the bacteria The observed patterns of localisation ... play a role for uptake of bacteria and intracellular replication [25] However, the model may have several pitfalls The uneven distribution of the inoculum may indicate an impaired intestinal ... surgical procedures and drafting of the manuscript JSA and TKJ participated in designing the study, interpretation of results and drafting of the manuscript All authors read and approved the final...
Ngày tải lên: 12/08/2014, 18:22
Development and application of a high throughput assay for discovery of starch hydrolase inhibitors
... αglucosidase and α-amylase can significantly reduce the post-prandial increase in blood glucose after a meal, with starch as the major calorie intake The apparent advantage of the starch hydrolase ... which can be measured at 540 nm (Figure 2) The advantages of this method are that a large quantity of the samples can be assayed at one time, and it also uses natural substrates such as maltose and ... fungal amylase is not a good model enzyme [23] Human pancreatic α-amylase (HPA) is an important pharmacological target for the treatment of type-2 diabetes However, the cost of the HPA is relatively...
Ngày tải lên: 10/09/2015, 09:01
Formulation and application of a new critical state model for clays
... UMAT for the AZ-Cam clay model in ABAQUS 267 VIII SUMMARY Realistic modeling of the mechanical behavior of soil with reasonable material input is essential for the practical use of numerical ... solving practical boundary value problems, however, the accuracy of the numerical methods depends the characterization of the mechanical behavior of the material Generally all the numerical results ... evaluate the capability of the proposed model A well conductor in soft clay subjected to lateral loading is then simulated by using the proposed AZ-Cam clay model in the commercial software ABAQUS...
Ngày tải lên: 02/10/2015, 17:15
Báo cáo y học: " Treatment of oroantral fistula with autologous bone graft and application of a non-reabsorbable membrane"
... amoxicillin and clavulanic acid g The fixed partial prosthesis was removed and the contiguous mucosa appeared healthy A buccal full thickness flap was harvested and the presence of a small OAF was verified ... characteristics of OAC/OAF; the apexes of tooth 26 were in extremely close approximation to the maxillary sinus, and an area of periapical rarefaction was evident (Fig 1) After the failure of the endodontic ... surgical closure is often indicated 1,2 Oroantral fistula (OAF) is an epithelialized communication between the oral cavity and the maxillary sinus The fistula is established for migration of the...
Ngày tải lên: 25/10/2012, 11:48
Báo cáo khoa học: "Combining EM Training and the MDL Principle for an Automatic Verb Classification incorporating Selectional Preferences" pot
... set to a tractable size The fact that verbs select for concepts rather than individual words also reduces the number of parameters and helps to avoid sparse data problems The application of the ... concept class is assigned a fraction of the frequency of the whole data set (and the top concept receives the total frequency of the data set) For calculating p(concept) (and the overall data length), ... from parsed data, or from a treebank Because of the hidden variables, the model is trained iteratively with the Expectation-Maximisation algorithm (Baum, 1972) The parameters are randomly initialised...
Ngày tải lên: 08/03/2014, 01:20
báo cáo hóa học:" Application of a disease-specific mapping function to estimate utility gains with effective treatment of schizophrenia" pot
... be expanded as new drugs are developed The mapping function applied in this study has technical advantages and disadvantages The health states are based on a combination of clinical data and expert ... that this is an optimal mix because it is a datadriven approach that compensates for under-representation of certain types of patients in clinical trials [16] A second advantage is the software ... statistical analyses and helped draft the manuscript All authors have read and approved the final manuscript Acknowledgements This study was supported by Janssen Medical Affairs, L.L.C The authors...
Ngày tải lên: 20/06/2014, 15:20