appi a new ionization source for lc ms ms assays

analytical method validation and instrument performance verification

analytical method validation and instrument performance verification

... sample The data variables that can be used for quantitation of the analyte are the peak areas, peak heights, or the ratio of peak areas (heights) of analyte to internal standard peak Quantitation ... programs for automatic or semiautomatic calculation and visualization of data The authors of this book come from a broad cultural and geographical base of pharmaceutical companies, vendors and ... POTENCY VALIDATION DATA It is very useful to summarize all method validation data into a tabular format The tabulated summary will give a quick overview of the validation data Often, the analyst may...

Ngày tải lên: 03/06/2014, 01:15

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FOREST AND PAPER INDUSTRY - A mature industry that has done much to clean up its act. pptx

FOREST AND PAPER INDUSTRY - A mature industry that has done much to clean up its act. pptx

... virgin magazine paper (as used for high-end magazines) uses a little more than 15 trees (15.36) ton of coated, lower-end virgin magazine paper (used for newsmagazines and most catalogs) uses nearly ... made with recovery of paper for recycling For reference: - The American Forest & Paper Association had set a recycling target of 55% for 2012 We take satisfaction in noting that this target was ... requirement: Paper must be made from a fibrous material Fibers can be found in biomass other than wood For example: KENAF - Kenaf is a plant originating from Africa and is a member of the hibiscus family,...

Ngày tải lên: 09/03/2014, 00:20

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báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc

báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc

... LTB4 and LTE4as analytical standards and the labelled [2H4] LTB4 and [2H4] PGE2 as internal standards were purchased from Cayman Chemicals Company (Michigan, USA) All analytical standards had chemical ... chemical purity >98% Acetonitrile was purchased from J.T Baker (Germany), methanol (GC-grade), acetic acid (glacial, pro analysi) and ammonium acetate p .a was purchased from Merck (Darmstadt, Germany) ... Bi-distilled water was used for HPLC mobile phase mixture Standard preparation and internal standardization A stock solution was prepared containing 10 µg/mL of each described analytes in ammonium acetate...

Ngày tải lên: 20/06/2014, 00:20

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Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

... 0.995 and calculated the average accuracy of the remaining data to be 0.99915 Applying this average accuracy to other datasets as a rough approximation to a per-call accuracy of 0.995, CRLMM achieves ... first pass runs of variable albeit typical quality Two 6.0 array datasets, from 44 and 96 HapMap samples, were run at the Chakravarti laboratory for testing purposes The other Chakravarti laboratrory ... then applied to high quality published Affymetrix HapMap data and newer first pass HapMap array data from the Broad Institute and Affymetrix To compare the two algorithms, we generated accuracy...

Ngày tải lên: 14/08/2014, 08:21

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Anchorage and resistance to uprooting forces of eelgrass (Zostera marina L.) shoots planted in slag substrates

Anchorage and resistance to uprooting forces of eelgrass (Zostera marina L.) shoots planted in slag substrates

... substrates MATERIALS AND METHODS Eelgrass collection and acclimatization The eelgrass plants were taken from well established eelgrass beds of Yoshina tidal flat in Seto Inland Sea, Japan at a depth ... Nishijima W and Okada M (2009) Evaluation of blast furnace slag as basal media for eelgrass bed J Hazard Mater., doi:10.1016/j.jhazmat.2008.12.037 Holmer M and Nielsen S.L (1997) Sediment sulfur dynamics ... (2000) Spartina alterniflora marshes on dredged material: a critical review of the ongoing debate over success Wetlands Ecology and Management (5), 295-316 Takahashi, T and Yabuta, K (2002) New Applications...

Ngày tải lên: 05/09/2013, 09:38

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Optimal cost and allocation for UPFC using HRGAPSO to improve power system security and loadability

Optimal cost and allocation for UPFC using HRGAPSO to improve power system security and loadability

... and co-author of about 18 papers in international journals and national and international conferences E-mail address: tawfik.guesmi@istmt.rnu.tn Hsan HADJ ABDALLAH was born in Sfax (Tunisia) in ... optimization and standard genetic algorithm, some improved mechanisms based on non-linear ranking selection, crossover and mutation are adapted in the genetic algorithm, and dynamical parameters are ... can make balance between acceleration convergence and averting precocity as well as stagnation In the literature, many power flow algorithms are proposed The majority of these methods are based...

Ngày tải lên: 05/09/2013, 15:28

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Tài liệu Windows Registry Clean up pptx

Tài liệu Windows Registry Clean up pptx

... applications and programs you use Uninstall all programs you aren’t using and reboot Once that is complete pull up your list of installed applications and make sure they are all gone? Use the above hack ... keys old programs leave behind All programs you install modify your registry in some way Unfortunately most programs don’t fully clean up after themselves when you uninstall them This causes your ... important to make sure you are in the right key because at this point we are going to start making some changes Look at the contents of the right pane It shows a column for name, type, and data If...

Ngày tải lên: 24/12/2013, 02:15

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Tài liệu HARBORING POLLUTION: Strategies to Clean Up U.S. Ports doc

Tài liệu HARBORING POLLUTION: Strategies to Clean Up U.S. Ports doc

... NY/NJ Charleston Oakland Hampton Roads Seattle Savannah Houston Miami Singapore Note: Data used to prepare this graph are explained in Appendix A expand As a result, new industrial operations are ... disorientation, confusion of biological rhythms that are adapted to a day/night alternation, and a general degradation of habitat quality This pollution can cause high mortality in animal populations, ... used for nonroad and on-road vehicular applications According to the International Organization for Standardization (ISO 8217), 19 categories of marine residual fuels are available internationally...

Ngày tải lên: 17/02/2014, 11:20

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Tài liệu DIVISION OF HEALTH CARE FINANCING AND POLICY MEDICAID AND NEVADA CHECK UP FACT BOOK pdf

Tài liệu DIVISION OF HEALTH CARE FINANCING AND POLICY MEDICAID AND NEVADA CHECK UP FACT BOOK pdf

... providing acute medical treatment Q12 What does managed care mean and why I need to select a Managed Care Plan? A1 2 Being in a managed care plan means when a person needs health care they will always ... Part A coverage, and supplemental medical insurance, known as Part B coverage Coverage for Part A is automatic for persons aged 65 and older and for certain persons with disabilities that have ... Fiscal Agent Audits; Contractor Audits; and Payment Error Rate Measurement (PERM) and Internal Audits Fiscal Agent Audits The DHCFP is contracted with a fiscal agent that performs a myriad of...

Ngày tải lên: 18/02/2014, 15:20

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Tài liệu Helpful Hints for Clean-Up pdf

Tài liệu Helpful Hints for Clean-Up pdf

... you blacked in the drawing would it still read? Avoid ambiguity - the "kinda, sorta, maybe" that makes areas mushy and uncertain Create a drawing that is solid, not timid! Avoid the "sawtooth ... chart (ie: a key has a chart for "Right arm" - everything that is not the right arm is the balance) T/B - Traceback ( a drawing traced back from the previous one) Ruff - Rough animation drawing ... Indicate eyelashes on male characters with a darker line and slight overlap for depth Make certain that eyelids are hinged on outer corner - not like a pull blind Additional Tips To make a change...

Ngày tải lên: 21/02/2014, 15:20

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Tài liệu EGERTON RYERSON AND Education in Upper Canada docx

Tài liệu EGERTON RYERSON AND Education in Upper Canada docx

... be built at once at Kingston and at Niagara, and, as soon as circumstances would permit, at Cornwall and at Sandwich The university was to be at York It was estimated that each grammar school ... Canada The Great Lakes and larger rivers were the natural highways It happened, therefore, that the earliest settlements were along the St Lawrence, the Niagara, and Lakes Erie and Ontario For a ... Legislature set apart £150 as an annual grant for purchasing books and tracts designed to afford moral and religious instruction By the creation of a General Board of Education, Rev Dr Strachan...

Ngày tải lên: 21/02/2014, 21:20

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Menopause and Osteoporos is Update 2009 ppt

Menopause and Osteoporos is Update 2009 ppt

... but may help prevent cardiovascular diseases and possibly ovarian cancer.10 Adequate calcium and vitamin D intake is necessary to attain and maintain normal bone quantity and quality and thus achieve ... disease and hypercalcemia related to malignant disease Zoledronic acid, mg intravenously on an annual basis, has been approved in Canada for the treatment for Paget’s disease and postmenopausal osteoporosis ... Levine MA Potential interactions between pharmaceuticals and natural health products in Canada J Clin Pharmacol 2007;47:249–58 10 Moss K, Boon H, Ballantyne P, Kachan N New Canadian natural health...

Ngày tải lên: 05/03/2014, 16:20

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World Economic Situation and Prospects 2012: Update as of mid-2012 docx

World Economic Situation and Prospects 2012: Update as of mid-2012 docx

... Nigeria 4.3 South Africa 3.2 Others 6.2 East and South Asia 7.6 East Asia 7.7 China 11.4 South Asia 7.2 India 8.4 Western Asia 3.5 Latin America and the Caribbean 3.2 South America 4.2 Brazil ... Latin America and the Caribbean; especially as it would likely lead to a renewed global slowdown, with weakening demand in China and the United States, Latin America’s main export destinations ... funds available for Italy Such a scenario would likely involve renewed speculation about a break-up of the euro area, further unsettling financial markets and triggering a sharp downturn in global...

Ngày tải lên: 08/03/2014, 06:20

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TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf

TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf

... intake can lead to a related state (hyperosmolar coma) Type diabetes is notable for the increased cardiovascular risk that it carries This can be manifest as coronary artery disease (heart attacks, ... Information for National Collaborating Centres and Guideline Developers’ Manual1 q NCC-CC quality assurance document and systematic review chart available at www.rcplondon.ac.uk/clinical-standards/ncc-cc/Pages/NCC-CC.aspx ... thrombogenicity, laser therapy for eye damage, drug therapy to delay kidney damage, local foot care, and symptomatic treatments for various types of nerve damage As a result diabetes care is typically complex...

Ngày tải lên: 08/03/2014, 14:20

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 nanotechnology and electronics presentation updated september 2011

nanotechnology and electronics presentation updated september 2011

... great conductors to be used as transparent contacts Updated September 2011 cc by Georg Wiora Carbon nanotubes on a glass or plastic sheet allow manufacturers to make clear conductive panels for ... of Im St ag an e da fro rd m s N an at d io n Te a ch l In no st lo itut gy es A schematic diagram of the NIST nanowire transistor Updated September 2011 Transistors Instead of making transistor ... components and assembling them on a board, nanoscale transistors are grown together on a silicon wafer They look much different from the traditional transistors cc by Ângelo Antônio Leithold Nano Transistor...

Ngày tải lên: 15/03/2014, 22:06

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Blank values, adsorption, pre concentration, and sample preservation for arsenic speciation of environme

Blank values, adsorption, pre concentration, and sample preservation for arsenic speciation of environme

... Milli-Q water and tap water, and release of total arsenic from different laboratory materials Sample Milli-Q water Tap water Polyethylenea Polycarbonatea Glass 1a Glass 2a Glassb GlassHNO3 c ... these samples were very low, a slight transformation may already cause remarkable inaccuracy Thus, storage of the treated samples at low temperature (e.g ◦ C) before analysis or immediate analysis ... speciation may lead to a false risk assessment of the environmental water samples Thus, a reliable pre-concentration method is a basis for a more precise speciation analysis for the less contaminated...

Ngày tải lên: 15/03/2014, 23:22

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Báo cáo khoa học: Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells pdf

Báo cáo khoa học: Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells pdf

... dependent pathway Oncogene 22, 548–554 Takahashi-Yanaga F, Taba Y, Miwa Y, Kubohara Y, Watanabe Y, Hirata M, Morimoto S & Sasaguri T (2003) Dictyostelium differentiation-inducing factor-3 activates ... DIF-1 Statistical analysis Statistical significance was assessed by analysis of variance (post hoc Fisher’s protected least significant difference) Acknowledgements We thank Ms Akiko Arai (Gunma University, ... DMEM-LG for several days and loaded with lm Fura-2 ⁄ AM (acetoxymethyl ester) (Dojindo, Tokyo, Japan) in Hank’s balanced salt solution (Nissui, Tokyo, Japan) for 30 at room temperature The Fura2-loaded...

Ngày tải lên: 23/03/2014, 09:20

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Báo cáo khoa học: Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding pot

Báo cáo khoa học: Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding pot

... the N-terminal a ⁄ b-domain and the C-terminal lassodomain (Fig 1) The a ⁄ b-domain is formed from a central, six-stranded, parallel b-sheet situated between a long a- helix, a1 , and a flexible loop ... thymine and the enzyme are to main-chain atoms such that O2 and N3 form hydrogen bonds to main-chain atoms of residues in the lasso-domain and O4 to main-chain atoms in the a ⁄ b-domain The methyl group ... interactions and the a- helix interactions are ˚ ˚ 970 A2 and 790 A2 , respectively, for Ba-TK, and ˚ ˚ and 413 A2 for Bc-TK, when residues 8–45 1030 A and 65–187 are used The a- helical interface area...

Ngày tải lên: 23/03/2014, 09:21

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east asia and pacific economic update 2011. navigating turbulence, sustaining growth

east asia and pacific economic update 2011. navigating turbulence, sustaining growth

... 99 navigating turbulence, sustaining growth v vi Abbreviations APEC ASEAN Asia-Pacific Economic Cooperation Association of Southeast Asian Nations ASEAN+3 Association of Southeast Asian Nations ... 2008 China Indonesia 2009 Malaysia Mongolia 2010 Philippines H1 2011 Thailand Sources: World Bank staff calculations using data from CEIC, Haver Analytics, and Thailand National Statistical Office ... total factor productivity improvements Indonesia China From capital accumulation Malaysia From human capital accumulation Thailand Korea, Rep From growth of labor force Source: WB staff calculations...

Ngày tải lên: 26/03/2014, 14:09

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