antiatherogenic effects of nitric oxide
Báo cáo y học: "Toxic effects of methoxychlor on the episodic prolactin secretory pattern: Possible mediated effects of nitric oxide production" pdf
Ngày tải lên :
10/08/2014, 09:20
... support of nitric oxide (NO) involvement in the cyclic release of prolactin and LH surges Brain Res 1994, 660:175-179 Gonzalez MC, Linares JD, Santos M, Llorente E: Effects of nitric oxide donors ... Nitric oxide inhibits the release of norepinephrine and dopamine from the medial basal hypothalamus of the rat Proc Nat Acad Sci USA 1995, 92:11299-11302 McCann SM: The nitric oxide hypothesis of ... Daspartate, nitric oxide and serotonin in the control of prolactin secretion in prepubertal male rats Eur J Endocrinol 1997, 13:99-106 Chiodera P, Volpi R, Coiro V: Involvement of nitric oxide in...
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báo cáo hóa học: " Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production" pdf
Ngày tải lên :
19/06/2014, 22:20
... dichlorofluorescin Nitric Oxide 1997, 1:359-369 Stasiolek M, Gavrilyuk V, Sharp A, Horvath P, Selmaj K, Feinstein DL: Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide ... temporal profiles of morphological change and release of cytokines and nitric oxide Neurosci Res 1999, 35:95-100 Feinstein DL, Galea E, Reis DJ: Norepinephrine suppresses inducible nitric oxide synthase ... Feinstein DL, Galea E, Reis DJ: Suppression of glial nitric oxide synthase induction by heat shock: effects on proteolytic degradation of IkappaB-alpha Nitric Oxide 1997, 1:167-176 Kim EJ, Kwon KJ,...
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Báo cáo y học: "Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13" docx
Ngày tải lên :
09/08/2014, 14:20
... effect of ASU on clinical symptoms of knee and hip OA, with a carryover effect that persists after termination of treatment [10-12] The primary aim of the present study was to explore the effects of ... FY: Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients J Exp Med 1996, 184:1519-1524 42 Stefanovic-Racic M, Stadler J, Evans CH: Nitric oxide and arthritis ... effectiveness of OA treatments is of significant importance, particularly if the treatment may also reduce or halt progression of the disease The pharmacological treatment of OA includes the use of agents...
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Role of nitric oxide in wound healing facilitatory effects of nitrosoglutathione a nitric oxide donor on the extracellular matrix deposition characteristics of wound healing
Ngày tải lên :
17/09/2015, 17:19
... Effects of NO donors and inhibitor on wound healing 151 5.2.1 Effects of GSNO on wound healing 151 5.2.2 Effects of SNAP on wound healing 155 5.2.3 Effects of GSH on wound healing 157 5.2.4 Effects ... 4.9.1.1.1 Effects of GSNO on MMP2 expression in scars 138 4.9.1.1.2 Effects of AG on MMP2 expression in scars 139 4.9.1.1.3 Effects of GSNO on MMP9 expression in scars 141 4.9.1.1.4 Effects of AG ... 4.2.1.2 Effects of AG on load to failure 102 4.2.2 Stiffness of the scars 104 4.2.2.1 Effects of GSNO, SNAP and GSH on scar stiffness 4.2.2.2 Effects of AG on scar stiffness 4.3 104 104 108 4.3.1 Effects...
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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx
Ngày tải lên :
22/02/2014, 04:20
... protein induction Effects of a-T and its derivatives on the enhancement by TS of LPS/IFN-induced NO production We compared the effects of a-T and its derivatives TA and TN with that of TS on LPS/IFN-induced ... GF109203X were approximately 70 and 30%, respectively Effects of TS on the amount of PKCa We further examined the effects of TS on the amounts of PKCa and PKCb by Western blotting As shown in Fig ... effects of a-T, TA and TN on the enhancement by 50 lM TS of LPS-induced NO production Values are means ± SD (n ¼ 3) *P £ 0.01 effects of a-T and its derivatives were not as clear as the effects...
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Báo cáo khoa học: Modulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitro doc
Ngày tải lên :
07/03/2014, 15:20
... suppression of the expression and activity of inducible nitric oxide synthase (iNOS) by zinc [32,33], released from MT under the influence of nitric oxide (NO), and the scavenging of NO through ... and CD spectra of metallothioneins devoid of any aromatic residues that Fig Wavelength and time scans of the CD of MT2 in the presence and absence of NO and GSH/GSSG CD spectra of 100 lM Cd5Zn2MT2 ... interactions of nitric oxide Cell 78, 931–936 Stamler, J.S., Simon, D.I., Osborne, J.A., Mullins, M.E., Jaraki, O., Michel, T., Singel, D.J & Loscalzo, J (1992) S-nitrosylation of proteins with nitric oxide: ...
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Báo cáo khoa học: Binding and activation of nitric oxide synthase isozymes by calmodulin EF hand pairs potx
Ngày tải lên :
16/03/2014, 13:20
... In the presence of Ca2+, the addition of an equimolar ratio of CaM to either of the peptides resulted in a significant increase in a-helical content The addition of equal amounts of either iNOS ... formation of aggresomes [35] This may provide a rapid means of clearing the cells of iNOS that would be detrimental to the cell because of its prolonged production of large amounts of •NO Our ... presence of excess wild-type CaM The addition of the excess native CaM appears to prevent the apparent aggregation of the protein This is likely to occur because of a change in the interaction of nCaM...
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Báo cáo khoa học: A pathway through interferon-c is the main pathway for induction of nitric oxide upon stimulation with bacterial lipopolysaccharide in mouse peritoneal cells pot
Ngày tải lên :
17/03/2014, 10:20
... Role of interferon regulatory factor in induction of nitric oxide synthase J Exp Med 180, 977–984 15 Weisz, A., Cicatiello, L & Esumi, H (1996) Regulation of the mouse inducible-type nitric oxide ... signals of LPS for the production of these mediators are transduced through CD14 Stimulatory effect of IFN-c and IL-12 + IL-18 on NO production by PEC of C3H/HeN and C3H/HeJ mice The role of IFN-c, ... production of IFN-c by nonadherent cells occurs independently of LPS, as neither adherent cells nor nonadherent cells of HeJ mice respond to LPS Effect of LPS stimulation on the activation of IRF-1...
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Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90 potx
Ngày tải lên :
23/03/2014, 07:20
... hydrolysis of a very limited number of peptide bonds; specifically, in the case of nNOS, degradation can occur with the cleavage of two peptide bonds and, in the case of eNOS, with the cleavage of a ... Degradation of NOS isozymes by calpain 44 Araujo IM, Ambrosio AF, Leal EC, Santos PF, Carvalho AP & Carvalho CM (2003) Neuronal nitric oxide synthase proteolysis limits the involvement of nitric oxide ... aliquots of each incubation (50 lL) as described in the Experimental procedures and is reported as a percentage of NOS activity assayed in the absence of calpain The amount of native band of HSP90...
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Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
Ngày tải lên :
23/03/2014, 09:21
... that of Ca2+-CaM [10,11,25,26], and therefore adversely affects binding of CaM to the Ca2+-CaM-binding domain of nNOS CaM is not only essential for the operation of nNOS and the other NOS isoforms, ... when it binds to the CaM-binding domain of endothelial nitric oxide synthase (eNOS) [33] The second example is when the C-terminal lobe of Ca2+-CaM binds part of the target peptide This is shown ... al Fig 15N HSQC spectra of CaM in the absence of cupiennin 1a (red), and with the addition of cupiennin 1a in a : molar ratio (purple) chiometry and providing evidence of slow exchange binding...
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Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
Ngày tải lên :
30/03/2014, 04:20
... University of Genoa References Kone BC, Kuncewicz T, Zhang W & Yu Z (2003) Protein interaction with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide ... degradation of nitric oxide synthase: effect of inhibitors and role of HSP90-based chaperones J Pharmacol Exp Ther 304, 493–497 13 Govers R, de Bree P & Rabelink TJ (2003) Involvement of the proteasome ... HSP90 and NOS degradation of the administration to the HSD-treated NMS animals of C.I.1 (Fig 5) In the brain of hypertensive rats, in spite of a preexisting condition of altered Ca2+ homeostasis,...
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báo cáo hóa học: " Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells" pptx
Ngày tải lên :
19/06/2014, 22:20
... iNOS, inducible nitric oxide synthase; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa B; NGF, nerve growth factor; NO, nitric oxide; nNOS, neuronal nitric oxide synthase; ... Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: Involvement of glutamate induced nitric oxide in motor neuron toxicity and nonmotor neuron protection Annals of ... nitric oxide and dementia of the Alzheimer's type Brain Res Brain Res Rev 2001, 35:73-96 de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, Wands JR: Aberrant expression of nitric oxide...
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Báo cáo khoa học: "Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis" pdf
Ngày tải lên :
07/08/2014, 14:22
... Fujimura, H and Yanagihara, T Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental ... Dijkstra, C D and Van der Valk, P Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis J Neuropathol ... expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomelitis 27 28 29 30 31 32 33 34 35 36 37 38 Induction of nitric oxide synthase activity in human astrocytes...
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Báo cáo khoa học: "Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development" ppsx
Ngày tải lên :
07/08/2014, 18:21
... Immunohistochemical localization of neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) isoforms of nitric oxide synthase (NOS) in the ovaries of pigs The intensity of staining is indicated by ... Dubey RK Role of nitric oxide in the biology, physiology and pathophysiology of reproduction Hum Reprod Update 1998, 4, 3-24 10 Shukovski L, Tsafriri A The involvement of nitric oxide in the ovulatory ... localization of inducible and endothelial nitric oxide synthase in the rat ovary Effects of gonadotropin stimulation in vivo J Clin Invest 1995, 96, 2719-2726 15 Xie QW, Nathan C The high-output nitric oxide...
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Báo cáo y học: "Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro" potx
Ngày tải lên :
11/08/2014, 03:20
... the inhibition of TGF-beta signaling in lung fibroblasts Respir Res 2006, 7:16-29 13 Tayler BS, Geller DA: Regulation of the inducible nitric oxide synthase (iNOS) gene In Nitric oxide and inflammation ... amounts of superoxide, which is responsible for the formation of the most toxic molecules, hydrogen radicals [21] Furthermore, down-regulation of iNOS expression suppresses the production of inflammatory ... least part of the therapeutic mode of action of the agent on chronic airway inflammatory diseases It is also suggested that M-4 will be a good candidate for the Page 11 of 12 treatment of chronic...
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Báo cáo y học: "Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro" pptx
Ngày tải lên :
11/08/2014, 06:22
... the inhibition of TGF-beta signaling in lung fibroblasts Respir Res 2006, 7:16-29 13 Tayler BS, Geller DA: Regulation of the inducible nitric oxide synthase (iNOS) gene In Nitric oxide and inflammation ... amounts of superoxide, which is responsible for the formation of the most toxic molecules, hydrogen radicals [21] Furthermore, down-regulation of iNOS expression suppresses the production of inflammatory ... least part of the therapeutic mode of action of the agent on chronic airway inflammatory diseases It is also suggested that M-4 will be a good candidate for the Page 11 of 12 treatment of chronic...
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Báo cáo khoa học: " Pichinde virus induces microvascular endothelial cell permeability through the production of nitric oxide" pot
Ngày tải lên :
12/08/2014, 04:20
... cytoplasm of infected cells (Fig 1A) This is the first report to our knowledge of PIC infection of human endothelial cells Effects of PIC infection on HMEC-1 permeability To investigate the effect of ... GAPDH (Qiagen) primer assay Quantitation of TNF-α and Nitric Oxide HMEC-1 cells were grown to confluency and infected with PIC at an MOI of Supernatants of HMEC-1 cell cultures were collected at ... effects of NO on the cardiovascular system are dependent upon the amount of NO produced, the local environment, and redox state of NO While low levels of NO are necessary for the integrity of the...
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Báo cáo y học: " Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus" potx
Ngày tải lên :
12/08/2014, 14:22
... role of endogenous nitric oxide Science 2003, 299:896-899 Nagy G, Barcza M, Gonchoroff N, Phillips PE, Perl A: Nitric oxide- dependent mitochondrial biogenesis generates Ca2+ signaling profile of ... Suppression of arthritis by an inhibitor of nitrice oxide synthase J Exp Med 1993, 178:749-754 van’t Hof RJ, Armour KJ, Smith LM, Armour KE, Wei XQ, Liew FY, Ralston SH: Requirement of the inducible nitric ... Textbook of Rheumatology 7th edn Elsevier, Saunders; 2005 van’t Hof RJ, Ralston SH: Nitric oxide and bone Immunology 2001, 103:255-261 Nagy G, Clark JM, Buzás EI, Gorman CL, Cope AP: Nitric oxide, ...
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Báo cáo y học: "Fluctuations of inspired concentrations of nitric oxide and nitrogen dioxide during mechanical ventilation" ppt
Ngày tải lên :
12/08/2014, 18:20
... C, Higenbottam T: Safety guidelines for use of nitric oxide Lancet 1992, 339:1615–1616 Sydow M, Bristow F, Zinserling J, Allen SJ: Variation of nitric oxide concentration during inspiration Crit ... Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn Lancet 1992, 340:819–820 Roberts JD, Polander DM, Lang P, Zapol WM: Inhaled nitric oxide in persistent pulmonary ... defect using low dose inhaled nitric oxide Intensive Care Med 1993, 19:75–77 Sellden H, Winberg P, Gustafsson LE, Lundell B, Böök K, Frostell CG: Inhalation of nitric oxide reduced pulmonary hypertension...
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