animal models and routes for retinal drug delivery
Báo cáo sinh học: " Equivalence of multibreed animal models and hierarchical Bayes analysis for maternally influenced traits" potx
... term in and aS (2) stands for the covariance between genotypic values for the parents of the individual, and can be developed further by expanding to the previous generation Under this formulation, ... a formal derivation of the equivalence through a somewhat different formulation from the one of GarcíaCortés and Toro [10] Further, we will expand the model to include maternal effects, and formalize ... diagonal elements and inverse of a large numerator relationship matrix Biometrics 1976, 32:949-956 39 Mrode RA: Linear models for the prediction of animal breeding values Wallingford, Oxfordshire, UK:...
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Tài liệu Báo cáo khoa học: "Models and Training for Unsupervised Preposition Sense Disambiguation" pptx
... different unsupervised training methods and discuss their respective advantages and disadvantages Unless specified otherwise, we initialized all models uniformly, and trained until the perplexity rate ... number of senses and instances For HMM, we set αtrans =100.0, βtrans =0.005, αemit =1.0, βemit =0.75 The subscripts trans and emit denote the transition and emission parameters For our model, we ... for the preposition against For both models, we set the concentration parameter αtrans to 0.001, and αemit to 0.1 This encourages sparsity in the model and allows for a more nuanced explanation...
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Báo cáo khoa học: LRRK2 in Parkinson’s disease: in vivo models and approaches for understanding pathogenic roles pdf
... mammalian models of LRRK2 The collective data obtained from both KO and transgenic mouse models (albeit in preliminary form) suggest that LRRK2 is not essential for neural development and differentiation, ... Xianting Li and Sarah Funderburk for their critical comments, and Dr Huaibin Cai for sharing unpublished results I am also grateful to Dr Nina Pan for assisting in the preparation of Fig and Table ... mouse models for neurodegenerative FEBS Journal 276 (2009) 6445–6454 ª 2009 The Author Journal compilation ª 2009 FEBS 6449 Approaches for understanding pathogenic roles Z Yue Table In vivo models...
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models and analysis for distributed systems
... www.mefosyloma.fr 2011 This acronym stands for Formal Methods for Software and Hardware Systems (in French) Laboratoire d’Informatique de Paris Laboratoire d’Informatique de Paris Nord Laboratoire ... understand for a non-specialist, grasping the full picture can be a challenge Moreover, system validation cannot be exhaustive Therefore, formal models aim to tackle these problems 2.3 Formal models ... %%first-order formulae end The language includes constructs for modular design of specifications: union and and then extensions can be used for specification structuring spec N OM S PEC= SP1 and and SPj...
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broadband services business models and technologies for community networks
... Autonoma di Trento and Informatica Trentina 5.5 Summary Models for Public Sector Involvement in Regional and Local Broadband Projects Gareth Hughes 6.1 Introduction 6.2 Overview of models for public ... user needs for broadband applications and services and the social and legal setting for its deployment and expected evolution The book starts by introducing the various applications and services ... ownership, Internet and broadband usage, the availability of popular games and other content and the comfort of well-known brands The second, and later, track will be the spread of broadband beyond the...
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Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... arthritis models and spontaneous models Several other models for arthritis have been reported but these will not be discussed here We believe that they should be considered as alternative models for ... also important for the induction of RA, play a role in RP pathogenesis Animal models provide good tools in the search for potential autoantigens and candidate genes in RP, RA and related autoimmune ... response in RA Animal models for RP have been described as those immunized with either collagen type II (CII) or matrilin-1 and as models that appear spontaneously [1–3] These models differ in...
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Báo cáo y học: "CD134 as target for specific drug delivery to T cells in adjuvant arthritis" pps
... rats per group for t = 0, n = rats per group for t = 7, n = to rats per group for t = 10, n = to rats per group for t = 14, n = to rats per group for t = 21, and n = to rats per group for t = 35 ... (AVLEDPYILLVSSKV) and OVA323–339 (ISQAVHAAHAEINEAGR) (OVA stands for Ovalbumin) were obtained from Isogen Bioscience (Maarssen, The Netherlands) mAbs and second-step reagents The anti-CD134 (OX40) and anti-CD25 ... Netherlands) Liposomes used for investigating in vitro binding and internalization contained 0.1 mol% Texas red-phosphatidylethanolamine (Molecular Probes Europe) Liposomes used for studying drug delivery...
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báo cáo khoa học: " Harm reduction services for British Columbia''''s First Nation population: a qualitative inquiry into opportunities and barriers for injection drug users" pdf
... overview of the availability and content of current HR practices; 2) identify barriers for HR services, and; 3) outline potential opportunities and recommendations for creating and facilitating HR practices ... compassion and more willing to listen and understand other ways of doing things." In addition to incorporating and respecting cultural practices, programs must also respect both age and literacy ... viewed as an opportunity for more successful program development and delivery For example, providing only a needle exchange program without additional education, counseling and other health services,...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 1 pptx
... language for comprehending each key element in the project environment and for visualizing how each element relates to the whole and to the others: • Models help us to explain and to understand how ... cause and effect relationships among the visual models, process improvement, and the achievement of peak performance; Frank Passavant for sharpening the core systems engineering messages, and particularly ... and particularly for his thoughtful and indepth critique of requirements management and the Dual Vee; and John Chiorini for clarifying the synergies among our primary messages and those of the...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 2 potx
... major cause for failure Organizing Staffing Planning Organizing Rationale for Expansion Planning Teams are newly formed for each project and include subcontractors and outsourcing Formulate Proactive ... Production: For standard production and/ or operational support, it is common to return to a functional form of management Development: For the development phases, a cross-functional team is formed and ... communication, pressure on suppliers, and the like These reviews should not be a forum for blaming 25 26 USING MODELS AND FRAMEWORKS TO MASTER COMPLEX SYSTEMS and criticizing team members or they...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 3 pot
... need for exploratory technical investigation early in the cycle to pursue opportunities and reduce risk For example, we encourage early hardware and software requirements-understanding models and ... Project Information Center A project information center— or project-specific web site— should portray timely, accurate, and relevant information Sharing information with the team is a way of reinforcing ... length and cost among the proposed and active projects The project manager ’s challenge is to secure the necessary funds for the project at hand and to properly manage them Government and commercial...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 4 doc
... Verification and Verification and Verification/Validation Verification/Validation Preparation for System Preparation for System and Preparation for and Preparation for Integration and Integration and ... Plans and Validation Plans Lowest CI Lowest Component Verification/Validation Verification/Validation Component Component and Preparation and Verification for and Preparation for Verification and ... Verification and ValidationVerification Validation Plans Build-to, and Plans Architecture, Design-to, and ValidationVerification Build-to, and Plans and ValidationVerification Build-to, and Plans and...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 5 pot
... Department of Defense (DoD) and NASA for many years and is now a standard planning technique for projects of all kinds The Project Management Institute’s Practice Standard for Work Breakdown Structures ... in Chapters 12 and 16 These are common expectations of executive management, the customer, and the team members: • Timely, accurate information for teams to work well, information and ideas have ... must match the risks and recognition given for both individual and team efforts 195 THE PROJECT TEAM Executive Management Customer Buyer wants delivery as promised Buyer wants delivery as promised...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 6 doc
... Strategic and tactical planning, Artifact selection and development, Hardware and software development, Manufacturing and coding, Supplier selection, Verification, Shipping and handling, Deployment, and ... performance Enforced use of common software languages and Unsolicited proposal based on competitor ’s poor performance 239 OPPORTUNITIES AND THEIR RISKS Causative and Preventive Actions standards ... of sophisticated and powerful tools available for opportunity and risk analysis, such as decision trees and Monte 237 OPPORTUNITIES AND THEIR RISKS Carlo simulations These tools and others are...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 7 potx
... Reviews Peer reviews vary in rate and formality, from informal walkthroughs and “chalk talks” to formal peer group presentations Peer reviews can be highly effective and they can provide the additional ... 15.2 A dedicated Short Cycle Room quickly scan for pertinent new information The Project Information Center is an ideal location for all hands and project manager ’s reviews On small projects, ... best opportunity for all relevant stones to be turned and assumptions to be challenged The executive and customer reviews have two purposes: to aid visibility and provide a forum for corrective...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 8 pdf
... Component Verification for and Preparation and Component Verification and and Preparation for Verification and Preparation forand Subsystem Integration Verification Preparation for Subsystem Integration ... Verification and Verification, Validation Verification, Validation Preparation for System Preparation for System and Preparation for and Preparation for Integration and Integration and System Integration ... periods and thresholds Cost thresholds should be expressed in both percentage and absolute terms—say, for example, 20 percent or $20 thousand for current periods and 10 percent or $40 thousand for...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 9 ppt
... rigor and thoroughness of integration and the many facets of verification and validation There is no standard vocabulary for expressing the risk philosophy, but it is often expressed as “quick and ... differences between estimates and budgets and to resolve those differences to improve both schedule and cost performance SUSTAINING PERFORMANCE IMPROVEMENT Measuring performance determines where ... measurement lead to higher performance and probability for project success The PMI Organizational Project Management Maturity Model (OPM3) is a standard for organizational assessment and process improvement...
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Visualizing Project Management Models and frameworks for mastering complex systems 3rd phần 10 pps
... expectations and that are documented for the purposes of sharing, repetition, and refinement formal control of form, fit and functionality Each CI should have an identified manager and may have ... through staged delivery of increments and versions of increments and developing capability over time (multiple delivery) Bridges and tunnels require single delivery while light rail systems and software ... Follower readiness, 329 Forcing style (power/dominance), 330 Ford, Henry, 69 Ford automobiles, 127, 234, 376 Forms/templates, web site for, 401– 402 Formality, 67– 68 Formal testing, 160, 369...
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Development and application of computational methods and tools for adverse drug reaction and toxicity prediction
... ST+ drugs and 239 ST- drugs, 103 TdP+ drugs and 157 TdP- drugs were retained For study of serious psychiatric ADRs, 321 and 169 drugs were identified PADR- and PADR- respectively All the information ... base models and best ensemble models for SJS/TEN study 84 Table 6.2 Performances of best base models and best ensemble models for TdP study 85 Table 6.3 Performances ... best base models and best ensemble models for serious psychiatric ADR study 86 Table 7.1 Performance profile of SVM models on testing and validation set for AM data from CV and RS experiment...
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New models and algorithm for de novo peptide sequencing of multi charge MS MS spectra
... Comparing Before and After Post-Processing for ISB Result Comparing Before and After Post-Processing for Top-1 ISB2 Result Comparing Before and After Post-Processing for Top-1 GPM Result ... for Top-1 GPM Result Ranking of Pep-3 Candidate for ISB Data Ranking of Pep-3 Candidate for ISB2 Data Ranking of Pep-3 Candidate for GPM Data 7.1 7.2 7.3 ... GPM sensitivity and specificity results for MCPS vs other algorithms ISB2 sensitivity and specificity results for MCPS vs other algorithms ISB sensitivity and specificity results for MCPS vs other...
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