andrea damascelli probing the electronic structure of complex systems by arpes
Báo cáo khoa học: Probing the unfolding region of ribonuclease A by site-directed mutagenesis potx
Ngày tải lên :
16/03/2014, 18:20
... studied the effect of the mutations on the
thermodynamic and kinetic stability. The similarity of the
impact on both the thermodynamic and kinetic stabilities
suggests a predominant effect on the ... stability is caused by
destabilization of the native state relative to th e unfolded
state. The decrease in the thermodynamic s tability of the
other less s table v ariants, all of which were exclusively
obtained ... F
start
is the signal of the
substrate before the addition of enzyme, F
end
is the signal
after cleavage of all substrate, and [E] is the concentration of
RNase A .
CD spectroscopy
CD spectra of RNase...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
Ngày tải lên :
18/02/2014, 06:20
... present for the last four residues at
the C-terminus. The stereochemistry of the model has
been assessed using the program procheck [23]. Ninety
per cent of the residues fall in the most favoured
regions ... metal-
bound hydroxyl group onto the substrate, as observed
in other members of the amidohydrolase superfamily
[24,25]. However, as no structure of complexes with
either the substrate, product or inhibitors ... content of 50%. Data were pro-
cessed using the program mosflm [38], and the ccp
4 suite
of programs [39] was used for scaling. Structure deter-
mination for hACMSD was performed by means of
the...
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Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx
Ngày tải lên :
21/02/2014, 03:20
... A
˚
resolution by the molecular replacement method. The
schematic view of the overall structure is shown in Fig. 3A.
Theenzymeexistsasadimeroftheabc heterotrimer. There
is a noncrystallographic twofold ... cob(II)alamin by X-ray
irradiation [59]. Therefore, we believe that the structure
reported in this paper is also that of the glycerol
dehydrataseÆcob(II)alamin complex. The dihedral angle of
the northern ... from a bulk of water by the
corrin ring of cobalamin. Figure 4B shows the structure
around the enzyme-bound cobalamin. The cobalamin
molecule is bound between the a and b subunits in the
so-called...
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Tài liệu Đề tài " The causal structure of microlocalized rough Einstein metrics " pptx
Ngày tải lên :
16/02/2014, 05:20
... the form curl/π
(2)
+ E
(2)
.
5. Strategy of the proof of the Asymptotics Theorem
In this section we describe the main ideas in the proof of the Asymptotics
Theorem.
(1) Section 6. We start by ... given a detailed proof of the theorem by relying heav-
ily on a result, which we have called the Asymptotics Theorem, concerning
the geometric properties of the causal structure of appropriately ... I
+
0
is the future domain of the origin
on Σ
0
.
Remark 9.3. The proof of Corollary 9.2 requires an extension argument.
The estimates of the Asymptotics Theorem, which are uniform with respect
to the...
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Tài liệu Báo cáo khoa học: Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis docx
Ngày tải lên :
19/02/2014, 02:20
... to the
enzyme. This may indicate that the steric limitation of
the enzyme’s binding pocket takes place in the area
between the ortho and para positions of the aromatic
substrate.
On the basis of ... removes the steric hindrance and allows the
approach of 2IPA towards the catalytic iron.
Residue I248 lies at the entrance of the substrate-
binding pocket of the enzyme, leading to the substrate
channel. ... [14]. The lack of characterization of the
structural determinant of the substrate specificity of
the AtdA enzyme has thus limited its development as a
biocatalyst for the bioremediation of a wide...
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Tài liệu Báo cáo khoa học: "Understanding the Semantic Structure of Noun Phrase Queries" pptx
Ngày tải lên :
20/02/2014, 04:20
... best
IM:Type full time
IM:Title the godfather
Other the, in, that Other the, in, that Other the, in, that
Table 3: Label sets and their respective query segment examples for the intent class Movie, Job ... goal of
this work is to identify the semantic labels of IMs,
i.e., the attribute names they implicitly refer to. We
use A
c
to denote the set of IM semantic labels for
the intent class c.
Other
Additionally, ... name of an intent class.
For example, the IH of the query “alice in won-
derland 2010 cast” is “cast”, which is an attribute
name of Movie. By issuing the query, the user in-
tends to find out the...
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Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc
Ngày tải lên :
21/02/2014, 03:20
... A
˚
,
respectively, for the backbone of the two subunits. The
difference between rmsd of monomeric and dimeric species
is due to the indetermination of the reciprocal orientation of
the two subunits. The average ... was used to back calculate the NOESY
cross-peaks from the calculated structure to assess the
quality of the structure.
The final family was made up of 30 structures with the
lowest target function. ... is c onsidered. The c omparison of the
present structure with the X -ray structures of the human
oxidized protein ( 1SOS) [11] and its G 37R mutant [50]
show that the protein has the same folding...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
Ngày tải lên :
21/02/2014, 15:20
... to the active site. To dissect
the structure function relationships of the LPL carboxyl-
terminal domain, several residues predicted by the model
structure to be essential for the functions of ... modeling of the dimeric structure of LPL. Two dimeric model structures of LPL were constructed using
INSIGHT II
version 2000 on
a Silicon Graphics workstation. The model structure of the closed ... on the
crystal structures of the human, porcine, and horse PLs
(Fig. 1). A frontal view illustrates the overall saddle shape of
the dimeric structure and the key heparin-binding residues
in the...
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Publicly Funded Agricultural Research and the Changing Structure of U.S. Agriculture doc
Ngày tải lên :
06/03/2014, 15:20
... secure the services of eminent members of appropriate professions in the examination
of policy matters pertaining to the health of the public. The Institute acts under the
responsibility given to the ... 20418
NOTICE: The project that is the subject of this report was approved by the
Governing Board of the National Research Council, whose members are drawn
from the councils of the National Academy of Sciences, ... recognizes the superior
achievements of engineers. Dr. Wm. A. Wulf is president of the National Academy of
Engineering.
The Institute of Medicine was established in 1970 by the National Academy of Sciences
to...
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Báo cáo khoa học: The crystal structure of NlpI A prokaryotic tetratricopeptide repeat protein with a globular fold potx
Ngày tải lên :
07/03/2014, 16:20
... ª 2004 FEBS
the full-length HOP, they act to facilitate the assembly
of multichaperone regulatory complexes. The struc-
tural independence of these TPR domains, and the
presence of independent ... First, the only structures of
natural TPRs in the PDB (13 TPR-containing coordi-
nate sets) consist of nonglobular, extended arrays of
helices [9,10,13–21]. Second, the majority of these
(11 structures) ... TPR1 and TPR2A of
AB
DC
Fig. 2. Solubility of NlpI constructs and the structure of mature NlpI. (A) 10–20% gradient SDS ⁄ PAGE of NlpI expression products, showing
the insolubility of the 3-TPR construct...
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Báo cáo khoa học: "Understanding the thematic structure of the Qur’an: an exploratory multivariate approach" pdf
Ngày tải lên :
08/03/2014, 04:22
... another than to any other profile in the data set.
The profiles of G can be summarized by a vector s
whose dimensionality is that of the data, and each
of whose elements contains the mean of ... disparity in
the frequency of its occurrence in A and B is the
first significant finding of the proposed
methodology.
The scaling of the ‘Allah’ variable dominates
all the other variables. ... understanding their
thematic interrelationships the object of this
exercise—but it is not sufficient because it
provides no information about the thematic
characteristics of the clusters and the thematic...
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Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
Ngày tải lên :
16/03/2014, 00:20
... [27]. On the basis of the
Ping Pong mechanism, the acetylation rate (k
2
)of
NAT2 by the acetyl donor is independent of the trans-
acetylation rate (k
4
) of the arylamine substrate.
Because the values ... the active site. The more dras-
tic mutations, Y190I and Y190A, however, revealed
the importance of the phenyl ring of the Tyr side
chain on the pH dependence of enzyme acetylation.
Both of the ... trunca-
tions, the availability of the Tyr190 mutants makes it
feasible to conduct cell-based studies of the effects of
the stability of the acetylated enzyme intermediate on
the N-acetylation of aromatic...
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Báo cáo khoa học: Molecular mass of macromolecules and subunits and the quaternary structure of hemoglobin from the microcrustacean Daphnia magna ppt
Ngày tải lên :
16/03/2014, 13:20
... orientation.
Accordingly, the present data on the molecular mass
of the native Hb complex as well as the Hb subunits
are inconsistent. In addition, there are only two hypo-
thetical models concerning the structure of ... identification of the carbohydrates bound to
D. magna Hb subunits, saccharides were released by
methanolysis and separated by GC followed by MS.
Chromatograms of the carbohydrates of D. magna Hb,
of the ... of this interesting molecule.
The present study has contributed to this approach:
(a) the determination of the molecular mass of the
native Hb complex and its subunits as well as the
number of...
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The Economic Structure of Intellectual Property Law pot
Ngày tải lên :
16/03/2014, 15:20
... reduce
output by restricting the use of the property, and if so this is as much a cost of
the property right as the cost of the fence is. Suppose the owner of a shop-
ping center does charge for the use of ... for the
original. In the case of books and other printed matter, the copier may not be
able to match the quality of paper or binding of the original or the crispness
of the printing, and there ... numerous, the trans-
action costs of their buying the right to use the river from the factory may ex-
ceed the value of the right to them. In such a case a liability rule would be
better, whereby the...
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- 1
Báo cáo khoa học: Methods to monitor the quaternary structure of G protein-coupled receptors doc
Ngày tải lên :
16/03/2014, 22:20
... both by the orientation of the energy transfer
partners and by the distance between them [28]. The
fact that the efficiency of transfer varies with the
6th-power of the distance between the fluorophores
presents ... is not promoted by the
bivalent nature of the antibodies. In studies assessing
the effect of ligand-binding on the quaternary structure
of the receptors, the possibility that the antibodies
could ... in 50% of the maximal
efficacy (R
0
). As indicated by the Fo
¨
rster equation, the efficiency of
transfer varies inversely with the 6th-power of the distance. The
extreme steepness of the relationship...
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Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
- mở máy động cơ rôto dây quấn
- các đặc tính của động cơ điện không đồng bộ
- hệ số công suất cosp fi p2
- đặc tuyến hiệu suất h fi p2