and it goes a little something like this event flow
Cloning and characterization of a novel kelch like gene in zebrafish
... opportunity to understand biology and accelerate biomedical research However this represents just the data acquisition phase Faced with an avalanche of sequence data, researchers are now faced with ... Postlethwait and Talbot, 1997) The two main approaches of cloning mutated genes, positional cloning and candidate gene approach, have benefited greatly from the recent advances in zebrafish genomic ... development and genetics In addition to its developmental advantages, recent studies indicate that the zebrafish has a great potential to serve as a model for human disease that range from heart failure...
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báo cáo sinh học:" Narrowing the gap between eye care needs and service provision: a model to dynamically regulate the flow of personnel through a multiple entry and exit training programme" pdf
... interacts with its immediate neighbours and the system as a whole The inclusion of feedback and temporal features makes the model dynamic and non-linear rather than static and linear Nurse, ophthalmology ... theory this would allow any practitioner to increase his or her range of competences by both acquiring new ones and by lifting the standard of those already attained The advantage of this mobility ... Your research papers will be: available free of charge to the entire biomedical community At a later date, the financial data associated with the personnel flows will be addressed by adding the...
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Báo cáo y học: "because I am something special" or "I think I will be something like a guinea pig": information and assent of legal minors in clinical trials – assessment of understanding, appreciation and reasoning'''' pot
... daily as was the case with the licensed preparations for ADHD, was seen as an advantage and a reason for participation Six of seven parents, as well as of the children and ado- http://www.capmh.com/content/3/1/2 ... did work a little bit and improved me My leisure activities would be worse, if I had a visit on Friday or Tuesday, that's when I always have handball training, all day, and Thursday, that's when ... with somatically ill patients and few data are available in paediatric psychiatric patients It could be assumed that psychiatric disorders influence subjects' capacities and competences in particular...
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Managing and Practicing OD in an IT Environment - A Structured Approach to Developing IT Project Teams
... entry and contracting, the OD practitioner and IT project manager already have a mutual understanding of the environment in which the IT project operates, and of its goals and staff responsibilities ... groupware, specialized systems such as accounting packages, and Internet and World Wide Web sites and applications While the field of IT is as broad and diverse as the organizations and individuals ... communication and other processes The very act of creating and validating the charter is itself an intervention addressing both clarity about objectives and an understanding of leadership and stakeholder...
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Tài liệu Báo cáo khoa học: Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt
... an amino acid at a particular position for this family of plant cysteine proteases The primers used were 5¢-TTGCCTGAGCATGTT GATTGGAGAGCGAAAG-3¢ (forward) and 5¢-GGGAT AATAAGGTAATCTAGTGATTCCAC-3¢ ... cysteine proteases, ervatamin -A, ervatamin-B and ervatamin-C, have been isolated and purified from the latex of a medicinal plant Ervatamia coronaria and biophysically ⁄ biochemically characterized ... Chakrabarti C, Biswas S, Kundu S, Sundd M, Jagannadham MV & Dattagupta JK (1999) Crystallization and preliminary X-ray analysis of ervatamin B and C, two thiol proteases from Ervatamia coronaria...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Betaproteobacteria Proteobacteria, Betaproteobacteria Proteobacteria, Gammaproteobacteria Proteobacteria, Gammaproteobacteria ... (strain ADP1) Pseudomonas fluorescens Pf5 ATCC BAA-477 Actinobacteria, Actinobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria ... TLPs are indicated above the alignment: motifs A –C’ are indicated with straight lines and are labelled; b-strands are indicated with arrows and are labelled A H A single a- helix is indicated with...
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Báo cáo Y học: A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii potx
... to a large family of proteins sharing G-patch, RNA recognition motifs and a specific SF45 motif An initial similarity search revealed a clear similarity ( 30% sequence identity) with DNA repair/toleration ... the parasite migrates as 60 kDa protein instead of 50 kDa At this time, we have no explanation for the discrepancy between the apparent molecular mass and the native size of TgDRE in the parasite ... Toxoplasma gondii Mol Biochem Parasitol 99, 223–235 Pang, Q., Hays, J.B & Rajagopal, I (1993) Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage...
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The Carbon and Global Warming Potential Impacts of Organic Farming: Does It Have a Significant Role in an Energy Constrained World? pptx
... offers some additional, if smaller, potential for E and GHG gains (and again data for the Canadian food system is lacking) and a significant body of literature has examined relative E and GHG efficiency ... farm approach and compared one organic and one conventional arable farm on clay soil (both growing potato, sugar beet, wheat, carrot, onion and pea) and one organic and conventional vegetable farm ... hectares of land worldwide according to the FAO, and much farmland globally is assigned to non-food crops, suggesting that land availability is not as great a constraint as offered by organic critics...
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Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)
... and vomiting, anorexia abdominal pain - headaches - arthralgia (neuralgic pain in joints) - myalgia (muscular pain or tenderness), back pain - mucosal redness of the oral cavity, dysphagia (difficulty ... tachypnea (rapid breathing) ** Patients who progressed to phase two EHF almost always die (Ndambi et al., 1999) Late Complications: -Arthralgia - ocular diseases (ocular pain, photophobia and ... by an abnormally large death in wild Gorilla populations Clinical Observations Incubation period: 2-21 days Stage I (unspecific): -Extreme asthenia (body weakness) -diarrhea, nausea and...
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Outlines of Greek and Roman Medicine, by James Sands Elliott This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of docx
... his time He attempted to cure dislocations by uttering a nonsensical incantation: "Huat hanat ista pista sista damiato damnaustra!" He considered ducks, geese and hares a light and suitable diet ... there was compensation for this state of affairs at the heart of the Empire because strong streams of capable and robust recruits flowed in from Spain, Gaul, Britain and Illyricum At its commencement, ... read of a Roman ambassador who was sent to the King of Bithynia, in Asia Minor, and who had his skull trepanned The first regular doctor in Rome was Archagathus, who began practice in the city...
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Báo cáo khoa học: PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans doc
... and 1% (v ⁄ v) acetonitrile overnight at 37 °C with agitation Statistical analyses All results are expressed as mean ± standard error (SE), except where indicated Data were analyzed using graphpad ... radiolabeled with 32 P-orthophosphate as per Experimental procedures Total cell lysates and media were immunoprecipitated with anti-hPCSK9 IgG or anti-V5 IgG ?accolade "acc 1a" > and fractionated ... media containing 32P-orthophosphate, immunoprecipitated PCSK9 from cells and media, and analyzed samples by SDS ⁄ PAGE fractionation followed by phosphorimaging (Fig 5) Lanes and and and represent...
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Báo cáo khoa học: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids docx
... epithelial cells, we analyzed the effect of DPA, EPA, and DHA on activation of Jak2 and Stat5 Whereas DPA and EPA activated Jak2 and Stat5, DHA did not induce Jak2 and Stat5 phosphorylation (Fig 2A) ... differentiation effect of pregnancy Table Analyses of fatty acid ratio and relative contents of n-3 PUFAs EPA, DPA, and DHA in mammary glands Whole inguinal mammary fat pads were isolated and contents ... of DHA, DPA, and EPA for 36 h Total cellular protein was isolated, subjected to western analysis with antibodies against phosphorylated Jak2 and Stat5, and normalized with total Jak2 and Stat5...
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Báo cáo khoa học: Heterologous expression of a serine carboxypeptidase-like acyltransferase and characterization of the kinetic mechanism potx
... existence of a short-lived acyl-enzyme and a direct attack of the activated acyl acceptor l-malate Experimental procedures Plant material and yeast cells Tobacco plants (Nicotiana tabacum L cv Samsun) ... prerequisite for understanding the adaptation of hydrolases to catalyze acyltransfer reactions The kinetic characterization of AtSMT reaction revealed a random sequential bi-bi mechanism The ... K, Viitanen PV, Chapple C & Strack D (2002) Immunolocalization of 1-O-sinapoylglucose:malate sinapoyltransferase in Arabidopsis thaliana Planta 215, 26–32 Kozak M (1983) Comparison of initiation...
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Báo cáo khoa học: Cleavage site analysis of a serralysin-like protease, PrtA, from an insect pathogen Photorhabdus luminescens and development of a highly sensitive and specific substrate pdf
... Pa3 Pa4 Pa5 Pa6 Pa7 Pa8 Pa9 Pa10 Pa11 Pa12 Ac-EVYLVE-NH2 Ac-EVYLLE-NH2 Ac-EVYLAE-NH2 Ac-EVYAVE-NH2 Ac-EVYALE-NH2 Ac-EVYAAE-NH2 Ac-ELYLVE-NH2 Ac-ELYAVE-NH2 Ac-ELYLLE-NH2 Ac-ELYLAE-NH2 Ac-ELYALE-NH2 ... specificity of a serralysin -like enzyme Fig Cleavage site analysis of PrtA on oxidized insulin chain A (A) The position of cleavage sites (vertical arrows, a1 a3 ) and cleavage fragments (horizontal ... our measurements), and Aex and Aem are the absorbance of the sample solution at the excitation and the emission wavelengths PrtA activity was measured at or 20 lm Dabcyl– EVYAVES–Edans substrate...
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Báo cáo hóa học: "Research Article A Random Ant-Like Unicast Routing Protocol for Wireless Ad Hoc Sensor Networks and Performance Evaluation" pdf
... networks are not very sufficient, especially the performance evaluation and comparison with other algorithm are not enough In this paper, we present a random ant -like unicast routing (RAUR) algorithm and ... routing table to see if it has a path to the destination If not, it forwards the data message to a random neighbor If this random neighbor has a path to the destination, it forwards the message to ... trail, while evaporation provides a time limit on its availability Ants interpret a wide trail, which is diffused and expanded by the pheromones of many ants, as being more significant than a narrow...
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IT and the environment A new item on the CIO’s agenda? potx
... to make information such as engineering manuals and human resources material such as pay cheques available online was also aided by a high degree of teleworking and a large number of field staff, ... Sherman, a fashion brand, agrees that firms across the Atlantic are light years ahead of European organisations when it comes to technology waste and recycling “American firms will increasingly ... agrees Anja ffrench, a supply officer at Computer Aid International, a UKbased charity For an appliance like a refrigerator, the majority of the energy is consumed during its operation, whereas with...
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Báo cáo y học: "MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β" pdf
... the synovial tissue of patients with advanced rheumatoid arthritis or osteoarthritis: analysis with gas chromatography-mass spectrometry and pan-bacterial polymerase chain reaction Arthritis Rheum ... obtained from Sigma (Saint Quentin Fallavier, France) The First Strand cDNA synthesis kits and 32P dATP were from Amersham Pharmacia Biotech (Saclay, France) A Nucleospin RNA II extraction kit ... like to thank Patrick Garnero for pro-MMP-3 assay and Claude Philippe for technical assistance with real-time PCR We are grateful to Francis Raul, in whose laboratory cDNA array experiments Available...
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Báo cáo y học: " Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro" pdf
... Scanner 3000 7G (Affymetrix) GeneSpring GX 11 (Agilent) was used for the normalization, filtering and statistical data analysis of the Affymetrix microarray data The linear data was first summarized ... for further GO and pathway analysis GO and pathway over-representation analysis as well as further analysis of protein-protein interactions and transcription factor regulation were carried out using ... signal transducer and activator of transcription and (STAT1, STAT2) and IFN regulatory factor (IRF9) Downstream genes regulated by this mechanism include genes reported to have anti-viral activity...
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Báo cáo y học: " Non-operative management of blunt abdominal trauma. Is it safe and feasible in a district general hospital?" doc
... design, analysis and interpretation of data; drafting the manuscript IEK was involved conception and design, acquisition, analysis and interpretation of data; performed statistical analysis; ... was not a cut-off hematocrit value and therefore transfusion was rather empirical However, older patients (>70 years old) and patients with coronary disease were transfused when hematocrit was ... mechanisms Trauma severity was evaluated according to Injury Severity Score (ISS) and organ injury according to Injury Scaling and Scoring System [9] Patients' status in admission was evaluated...
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Development of a novel toll like receptor based two hybrid assay for detecting protein protein interactions and its application in the study of CD14 dimerization and FcyRIIA activation
... involved in galactose utilization GAL4 contains a DNA binding domain (BD) (Keegan et al., 1986) and a transcription activation domain (AD) (Brent and Ptashne, 1985) which are separately folded and functions ... kinase (TAK1) and its two adaptor proteins, TAK1-binding protein (TAB) and TAB2 TAB2, an adaptor linking TAK1 to TRAF6, is associated with cell membrane under unstimulated conditions TAK1 is a MAPKKK ... MyD88-independent pathway exists that leads to activation of IRF-3 via TBK1 and IKKε/IKKi The TIR domain-containing adaptor TRIF mediates this MyD88-independent pathway Adopted from Takeda and Akira et al.,...
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