... total polyphenols and antioxidant activity [24] Identification and quantification of caffeic acid as an active compound Figure (A) ABTS radical scavenging activities and (B) FRAP of fractions from ... was measured at a wavelength of 593 nm Intensity of the color is related to the amount of antioxidant reductants in the samples Identification and quantification of active compounds The most ... SAS (8.2 version, SAS Institute, USA) Results and discussion Total phenolics and antioxidant activities of various fractions of the methanolic extract of E annuus Neuronal cell culture PC12 cells...
Ngày tải lên: 13/08/2014, 14:20
... 5.3.1 AChE and BChE inhibitory activities 176 5.3.1.1 Inhibition of AChE and BChE at a fixed concentration (3 µM) of test compound 177 5.3.1.2 AChE and BChE inhibitory activities of selected ... levels of products of oxidation, lipoxidation, and glycoxidation.75 However, the administration of one or a few antioxidants to address the problem of neurodegeneration would be naïve and several ... improved antiprion activity.91 Klingenstein and co-workers13 observed the synergistic antiprion effects of quinacrine and iminodibenzyl-derived antidepressants, and this led to the synthesis of potent...
Ngày tải lên: 11/09/2015, 10:05
Báo cáo khoa học: Anti- and pro-oxidant effects of quercetin in copper-induced low density lipoprotein oxidation Quercetin as an effective antioxidant against pro-oxidant effects of urate potx
... absence of quercetin the prooxidant activity of urate masks its antioxidant activity as mentioned above, whereas, in the presence of quercetin, the pro -oxidant activity of urate disappears and its antioxidant ... one of the major plasma antioxidant Antioxidant properties of flavonoids have been widely studied within the last 20 past years A peculiar attention has been paid to the antioxidant effect of flavonoids ... Figs and 2C in terms of MDA production and on Fig 2D in terms of conjugated diene formation Interestingly, this pro -oxidant behavior is observed at low concentration of ÔantioxidantÕ In view of...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo Y học: Anti- and pro-oxidant effects of urate in copper-induced low-density lipoprotein oxidation pdf
... lM) a pro -oxidant behavior is < observed whereas the observation of antioxidant properties of urate requires higher urate concentration ( 800 lM) The switch between the pro- and antioxidant properties ... (endogenous) antioxidants are consumed, before the propagation phase corresponding to the chain reaction (reactions and 5) The formation of conjugated dienes and the consumption of endogenous antioxidants ... in contrast to native LDL and in agreement with others, antioxidant concentrations of urate (50 lM and 800 lM with 175 and lM of Cu2+, respectively) are denitely pro -oxidant when preoxidized LDL...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"
... [1,10,12] Anti- CCP antibodies can also induce or enhance arthritis and tisuue demage in the mouse [13] The effects of anti- CCP antibodies on whole blood, serum and synovial fluid oxidant and anti- oxidant ... of anti- CCP antibodies 140 in the circulation on whole blood, serum and synovial fluid oxidant and anti- oxidant capacity in patients with RA Methods RA patients with anti- CCP (+) (n=25) and anti- CCP ... Nonsignificant Table Serum and whole blood oxidant activity; MDA and MPO levels, and antioxidant activity; CAT and GSH-Px levels in anti- CCP(+) and anti- CCP(-) patients with RA Anti- CCP negative positive...
Ngày tải lên: 25/10/2012, 11:15
báo cáo hóa học: " In vitro anti-leishmanial and anti-fungal effects of new SbIII carboxylates" pot
... of Synthesis of antimony complexes Aqueous solution of SbCl3 was made by dissolving 0.5 g (2.19 mM) in 10 mL, and a few drops of dil HCl were added; to this solution, equimolar amount of ligand ... [16] Broad band observed for carboxylic group disappeared in the spectra of complexes indicating deprotonation of ligand In the spectra of compounds V-VIII, appearance of new band of medium intensity ... serum; 25 mM of HEPES, and 0.22 μg of penicillin and streptomycin, respectively at 24°C in an incubator mg of each test compound (I-VIII) was dissolved in mL of water, ethanol, methanol and DMSO...
Ngày tải lên: 21/06/2014, 02:20
Báo cáo khoa học: " The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats" pot
... fraction of BP (BPE) and hexane fraction of BP (BPH) were extracted from whole BP and antinociceptive and anti- inflammatory effect on experimentally evoked RA in rats was demonstrated Materials and ... soft tissue swelling and bone proliferation Each value was calculated by these equations; (1) Area of soft tissue = [whole area of paw] - [bone area] (2) Area of soft tissue swelling = [area of ... inflamed soft tissue] - [area of normal soft tissue] (3) Area of bone proliferation = [area of proliferated bone] - [area of normal bone] S erum concentration of interleukin-6 At the end of whole...
Ngày tải lên: 07/08/2014, 15:20
Báo cáo y học: "Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27" pptx
... augment proliferation and secretion of IFN-γ by naïve CD4+ T cells [3,39,40] and when combined with The paradoxical pro- and anti- inflammatory properties of IL-27 Through ligation of its cognate receptor, ... IL-27 expression Ligation of TLR9 with double stranded DNA leads to strong induction of IL-27 in murine bone marrow derived DCs and engagement of TLR2 with its synthetic ligand (Pam3Cys) promotes ... IL-6 and TNF-α than wild-type counterparts (Figs and 3) [53] Since ablation of STAT3 in myeloid cells results in elevated production of IL-6, TNF-α and IL-12 [63], it is possible that a lack of...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: "Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorith" ppsx
... the loss of viability of vaginal cells and Lactobacillus species [17,18] Page of 13 The present study focuses on a comprehensive assessment of the use of natural and neutralized lime and lemon ... Juice and Household Vinegar are Toxic to Immortalized and Primary Cells, and Toxicity is Reduced by pH Neutralization The antiviral and cytotoxic effects of natural and pH neutralized lemon and ... The pH of freshly squeezed lemon and lime juice ranged from 2.1-2.4 and 2.2-2.3, respectively The pH values of orange and grapefruit juices were 3.3 and 3.0, respectively Apple (pH 3.7) and tomato...
Ngày tải lên: 10/08/2014, 05:21
báo cáo khoa học: "Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma" docx
... after months of temsirolimus To assess the extent of the therapeutic effect, and to detect a possible early recurrence, a second biopsy of the same right cervical lymph node was Page of performed ... thalidomide and chlorambucil treatment On March 2009, all lymph nodes enlarged, and disease still progressed after cycles of bortezomib The patient finally died of severe bone marrow inhibition and pulmonary ... treatment, leukopenia and thrombocytopenia occasionally occurred, and disappeared after one week of treatment suspension No sign of thrombosis was observed Cyclin D1, the hallmark of MCL, is the down...
Ngày tải lên: 10/08/2014, 22:21
báo cáo khoa học: "Anti-oxidant effect of gold nanoparticles restrains hyperglycemic conditions in diabetic mice" ppt
... 0.1 ml of plasma, 3.3 ml of water, 0.3 ml of 10% sodium tungstate and 0.3 ml of 0.67 N sulphuric acid reagents were added The suspensions were centrifuged and to ml of supernatant, 0.4 ml of diacetylmonoxime ... Figure Influence of gold nanoparticles over the anti- oxidant system in experimental mice The gold nanoparticles restored the elevated level of antioxidant enzymes such as GSH, SOD, GPx and catalase ... nanoparticles' potential as antioxidant is shored up with previous reports delivering the control effects of gold nanoparticles as an antioxidant [37] and potential of other rare earth metals...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: "In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin." potx
... possible anti- inflammatory and anti- thrombotic properties of antibiotics used in sepsis treatment through their anti- PAF or anti- thrombin activities This is the first study to report the anti- inflammatory ... anti- inflammatory and anti- thrombotic activities of a wide spectrum of antibiotics through their effects on PAF biological activities and its metabolism, as well as on thrombin We also studied the effect of ... study to bring in surface putative antiinflammatory and anti- thrombotic activities of some antibiotics used in sepsis, through their in vitro studied anti- PAF and anti- thrombin effects in rabbit...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin" doc
... possible anti- inflammatory and anti- thrombotic properties of antibiotics used in sepsis treatment through their anti- PAF or anti- thrombin activities This is the first study to report the anti- inflammatory ... anti- inflammatory and anti- thrombotic activities of a wide spectrum of antibiotics through their effects on PAF biological activities and its metabolism, as well as on thrombin We also studied the effect of ... study to bring in surface putative antiinflammatory and anti- thrombotic activities of some antibiotics used in sepsis, through their in vitro studied anti- PAF and anti- thrombin effects in rabbit...
Ngày tải lên: 11/08/2014, 06:23
Báo cáo y học: " Early Anti-inflammatory and anti-arthritic effects of yucca schidigera: A review" pdf
... Journal of Inflammation 2006, 3:6 erant of yucca extract and yucca saponins [31] Thus, a beneficial effect of yucca on arthritis could involve antiprotozoal, anti- oxidant and anti- bacterial activities ... remarkably potent inhibitor of NFkB activity and tumor necrosis factor production." Evaluation of the anti- inflammatory activity of a combination of yucca and cat's claw would be of interest http://www.journal-inflammation.com/content/3/1/6 ... any merit, a role of yucca in arthritis treatment can be advanced on the basis of the anti- protozoal activity of yucca saponins The chemistry and bioactivity of yucca saponins and phenolics have...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression" pps
... and the inhibition of these genes by anti- oxidants The anti- oxidants NAC and DMSO strongly inhibit HA fragment induced TNF-α and KC in alveolar macrophages The effect of anti- oxidants was not limited ... metalloproteases and nitric oxide synthase [20-25] The potent antioxidants N-acetylcysteine (NAC) and dimethyl sulfoxide (DMSO) have been shown to possess both anti- inflammatory and anti- fibrotic ... signal transduction and gene activation, and can contribute to host cell and organ damage [2] When cellular production of ROS overwhelms its antioxidant capacity, a state of oxidative stress...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo sinh học: "Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens" ppsx
... inhibitory and minimum bactericidal concentrations in μg/ml of thymoquinone and tetracycline and their combination MIC TQ MBC TQ MIC TET MBC TET a MIC TET + 1/2MIC TQ MBC TET + 1/2MIC TQ References ... ATCC 14579 and S aureus B285 (Table 2) The antibacterial activities of TQ against the tested strains were shown in Table TQ demonstrated a selective antimicrobial property Seven out of 16 oral ... concentrations of TQ (0 to 200 μg/ml) prior to the addition of glucose Kouidhi et al Annals of Clinical Microbiology and Antimicrobials 2011, 10:29 http://www.ann-clinmicrob.com/content/10/1/29 Page of...
Ngày tải lên: 12/08/2014, 17:20
Báo cáo khoa học: "Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock" ppt
... for analysis of endotoxin, TNF-α and IL-6 were drawn immediately before addition of antibiotics and hourly until the end of the experiment At the same time points arterial blood gas and base deficit ... the initial log concentration of cytokines of at least 20% with an α error of 0.05, a β error of 0.2, a power of 0.8, and a calculated interindividual variation of 14%, eight evaluable animals ... Uniform and dose-dependent reduction by the addition of tobramycin Scand J Infect Dis 2003, 35:40-46 Evans ME, Pollack M: Effect of antibiotic class and concentration on the release of lipopolysacharide...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: " Integrase and integration: biochemical activities of HIV-1 integrase" pps
... be asymmetric [39] The catalytic activities of integrase (IN) 3'-processing and strand transfer There is now substantial virological evidence that the precursor of integrated viral DNA, or provirus, ... enzyme and the DNA as it is observed during catalytic reaction of topoisomerase or IN of lambda phage, for example The removal of the dinucleotides from the 5' overhang, of viral origin, and DNA ... as a cofactor [70-72], and the effects of mutations conferring drug resistance are often detectable only in tests using Mg2+ as the cofactor [73] These considerations have led to the use of chemical...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa " pdf
... Laboratories, anti- pERK, antiERK, anti- pJNK, anti- JNK, and anti- p-p38 were from Cell Signaling Technology, anti- p65 and anti- p38 were from Santa Cruz Biotechnology, anti- b-actin was from SigmaAldrich, anti- a-tubulin ... that ALBE may have antiallergic and anti- inflammatory effects Conclusions ALBE may exert anti- allergic and anti- inflammatory activities by suppressing the transcription of NF-B and the activated ... meaningfully inhibited the antigeninduced mRNA expression and production of cytokines related to allergic and atopic reactions Effects of ALBE on NF-B activation and phosphorylation of MAPKs in ConA-induced...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo y học: " Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components" docx
... impairment of memory and cognitive ability caused by the loss of hippocampal and cortical neurons, is related to accumulations of beta-amyloid [55] and disproportionate deficiency of acetylcholine ... 57(3):387-389 Page of 60 Park CH, Kim SH, Choi W, Lee YJ, Kim JS, Kang SS, Suh YH: Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa ... increased the CGRP and decreased TNF-a with significant improvement of cardiac function and inhibition of the sinus tachycardia in antigen induced cardiac anaphylactic injury of guinea-pig hearts...
Ngày tải lên: 13/08/2014, 14:20