anatomy and physiology of the cardiovascular system ppt

Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt

Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt

... particular, p21 is a direct target of SREBP [20]. The role of SREBP-1a in the regulation of cell growth and the cell cycle might be biphasic and complex, and needs to be further investigated. SREBP is ... which has been cloned as a regulator of adipogenesis [44]. The roles of SREBP-1c in adipogenesis are currently controversial. Physiology and pathophysiology of the SREBP family H. Shimano 618 FEBS ... resistance [48]. The exact roles of SREBP-1c ⁄ ADD1 are not yet fully defined. SREBP and parasympathetic function in heart Parasympathetic stimulation of the heart involves activation of GIRK1 ⁄ 4,...

Ngày tải lên: 18/02/2014, 13:20

6 574 1
Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx

Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx

... (Invitrogen), and the isolation of RNA followed the manufacture’s protocol. The synthesis of first-strand cDNA was per- formed using the Superscript preamplification system (Invitrogen). Either 5 lg of t ... of the product of P450scc-mediated side-chain cleavage of 7-DHC. (A) Spectrum of the enzymatic side-chain cleavage of 7-DHC; (B) spectrum of 7-DHP synthetic standard. Ó FEBS 2004 P450scc in the ... illustrates mass spectra of isolated 7-DHP-MO-TMS, and the synthesized standard. The molecular ion is at m/z 415, and distinctive ions are formed by loss of the silylated hydroxy, methyl and oxime groups at...

Ngày tải lên: 23/03/2014, 13:20

11 476 0
Tài liệu Color Atlas of Pharmacology (Part 12): Inhibitors of the RAA System ppt

Tài liệu Color Atlas of Pharmacology (Part 12): Inhibitors of the RAA System ppt

... cells in the wall of the afferent ar- teriole of the renal glomerulus. These cells belong to the juxtaglomerular ap- paratus of the nephron, the site of con- tact between afferent arteriole and dis- tal ... terms and conditions of license. Overview of Modes of Action (A) 1. The pumping capacity of the heart is regulated by sympathetic and parasym- pathetic nerves (pp. 84, 105). Drugs ca- pable of ... excitability of the cell membrane. When part of the en- zyme is occupied and inhibited by CG, the unoccupied remainder can increase its level of activity and maintain Na + and K + transport. The effective...

Ngày tải lên: 26/01/2014, 19:20

14 401 1
Tài liệu Báo cáo khóa học: Non-specific depolymerization of chitosan by pronase and characterization of the resultant products pptx

Tài liệu Báo cáo khóa học: Non-specific depolymerization of chitosan by pronase and characterization of the resultant products pptx

... (mL)/mass of sample (g) and the level of deacetylation was calculated by comparison between the number of free amino groups (per unit weight of the sample) and the equivalent weight of GlcN [23]. Circular ... convoluted spectral band around 3600–3000 cm )1 in the spectra of both chitosan and LMWC indicated the absence of free -OH groups and the involvement of both -OH… 3and -CH 2 OH…6 in intra- and intermolecular ... the release of GlcNAc and products with GlcNAc at the reducing ends. The observed decrease in DA value of LMWC is due to the release of GlcNAc and GlcNAc-rich oligomers as some of the products....

Ngày tải lên: 19/02/2014, 12:20

11 674 0
Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx

Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx

... human and rat CB 1 receptor. The CB 2 antibody was raised against a sequence between the N-terminal and the first trans- membrane domain of the protein of the human and rat CB 2 receptor. The specificity ... marrow stem cells, are the most potent antigen-presenting cells of the immune system. They play a central role in the initiation of primary immune response and in the enhancement of secondary immune ... as far as the amounts of the endogenous ligands are concerned, but differently in terms of the levels of the two cannabinoid receptor subtypes and FAAH. Indeed, inflammatory, allergenic and septic stimuli...

Ngày tải lên: 22/02/2014, 07:20

8 646 0
Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx

Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx

... the signal in the NT, which may be due to the low expression of goldfish LPXRFamide peptide mRNA. Otherwise, the localization of immunoreactive cell bodies in the NT may suggest the presence of ... to the partial fGRP sequence and the anchor primer, followed by reamplification of the first-round PCR products with degenerate primers corresponding to the other partial fGRP sequence and the ... substance was then examined by mass spectrometry. The mass values of predicted peptides were calculated on the basis of the sequence of goldfish prepro- protein. On the nano ESI-TOF-MS, a molecular...

Ngày tải lên: 08/03/2014, 16:20

9 383 0
THE STRUCTURE AND DEVELOPMENT OF THE CEREAL PLANT pptx

THE STRUCTURE AND DEVELOPMENT OF THE CEREAL PLANT pptx

... bases, so the oldest parts of a leaf are the tip of the blade and the top of the sheath. Where the blade and sheath join, there are structures called the ligule and the auricles (Figure 2.3). ... uptake into the plant is occurring, and is greater away from the plant roots. Because there is more of the element away from the root, most of the elements will move to the root. Therefore, the net ... Tim Setter and Peter Carlton The structure of the wheat plant described in this chapter is the starting point to understanding the growth and development of the crop, its nutrition and the reasons for...

Ngày tải lên: 08/03/2014, 23:20

86 710 0
Báo cáo khoa học: Bovine tryptases cDNA cloning, tissue specific expression and characterization of the lung isoform ppt

Báo cáo khoa học: Bovine tryptases cDNA cloning, tissue specific expression and characterization of the lung isoform ppt

... Furthermore, analysis of BLCT and BLT expression in bovine heart and spleen has shown that both enzymes are present in these tissues at the mRNA level. The simultaneous expression of the two isoforms ... negative charge at the bottom of the pocket and a consequent weaker interaction of substrates when compared with BLT and the other tryptases. The usual substrate specificity of BLCT was explained by ... prompted us to analyze the organiza- tion and the promoter sequences (Fig. 4) of the two tryptase genes. The length of both genes, as evaluated from the size of the PCR products, obtained from genomic...

Ngày tải lên: 17/03/2014, 09:20

11 527 0
The origin and evolution of the solar system   woolfson

The origin and evolution of the solar system woolfson

... scientific theory and there are many examples in the history of science that tell us so. The geocentric theory of the solar system, the phlogiston theory of burning and the concept of chemical ... between planets A and B 246 9 The Moon 251 9.1 The origin of the Earth–Moon system 251 9.1.1 The fission hypothesis 251 9.1.2 Co-accretion of the Earth and the Moon 254 9.1.3 Capture of the Moon from ... observed on the satellite. The basis of the prediction was the 2:1 ratio of the periods of Io and Europa. Because of this the nearest approach, and hence the maximum perturba- tion, of Io by Europa...

Ngày tải lên: 17/03/2014, 13:35

426 435 0
Báo cáo Y học: Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form ppt

Báo cáo Y học: Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form ppt

... enzyme system of rat liver. After incubation of the hydroxylase with 125 I-labelled Ub and a mixture of the purified preparations of the E 1, E2 and E 3 enzymes, the 2D-electrophoresis revealed the ... may play a role in the degradation of both membrane-bound and soluble TH. However, the accurate role of the ubiquitination remains t he subject of further investigation and the reason why TH is ... catalyzes the conversion of L -tyrosine to L -dihydroxyphenylalanine ( L -DOPA), the rate-limiting step in the biosynthesis of dopamine and noradrenaline/adrenaline [ 1]. The cellular activity of TH...

Ngày tải lên: 17/03/2014, 17:20

9 437 0
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