analysis of functional imaging data

... Mg2+ selective channel of high conductance This channel is made up of a homooligomer of Mrs2p (J Weghuber, R Schindl, C Romain & R.J Schweyen, unpublished data) In the absence of Mrs2p, yeast cells ... concentrations [Mg2+]m of about half of those of Mrs2p wild-type mitochondria [7] (J Weghuber, R Schindl, C Romain & R.J Schweyen, unpublished data) Except for the presence of two adjacent TM domains ... growth on YPdG medium (data not shown) Suppression of the mit– M1301 phenotype was comparable to that of the randomly generated gain-offunction mutations (Fig 2A and B) Loss -of- function alleles...

Ngày tải lên: 23/03/2014, 10:21

... 886 titles of potentially relevant articles from our search of computerized databases and 58 additional references from our manual search of the bibliographies of retrieved articles Of the 944 ... systematic review of reports of MTB infection in liver transplant recipients published between 1963 (the first report of a liver transplant) and 2007 to evaluate the effectiveness of pretransplant ... involvement), development of multiorgan MTB infection, development of isoniazid or rifampin hepatotoxicity, and presence of acute cellular hepatic rejection We adopted the definition of the Centers for...

Ngày tải lên: 29/03/2014, 03:20

... properties of the ECDs, the analysis of the statistical behavior of real data can be reduced to the study of the distributions of the scalar variable D The analysis was carried out in terms of a graphical ... a number of pixels large enough to neglect the errors in the estimate of the mean vector and the covariance matrix Thus, they reduced the analysis of the statistical behavior of real data to the ... to the study of the univariate distribution of D Note that, by assuming perfect knowledge of µ and C, the EC-t distribution depends on the parameter υ alone The analysis of HYDICE data was carried...

Ngày tải lên: 22/06/2014, 23:20

... the results of a logistic regression-based risk analysis utilizing forest management data The analysis was carried out in unnatural Norway spruce forests affected by different types of forest decline ... 74.1; P = 0.00 Corectness of classification on analyzed data (Orava region, n = 226) 78.3% Corectness of classification on independent data (Kysuce region, n = 286) 85.7% % of removed timber stock ... the numbers of damaged and undamaged stands in the sample data differ significantly The results indicate a possibility of under- or overestimation of predicted risk given unbalanced data sets, i.e...

Ngày tải lên: 07/08/2014, 10:21

... SEER database with an additional four years of data Page of Table Description of SEER ONB cohort (N = 511) Characteristic Frequency Percent Age (years) Methods Identification of Cases The SEER database ... come at the cost of limited documentation of treatment detail For example, the SEER database did not include type of surgical resection In a recent meta -analysis of patient data for ONB between ... stratified by treatment and consistent with one meta -analysis, smaller series and a previous examination of the SEER database, this analysis of SEER data shows that surgery with radiotherapy provides...

Ngày tải lên: 09/08/2014, 09:20

... BD: Imaging Subcommittee of International Harmonization Project in Lymphoma Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International ... presence of diffuse or nodular Peritoneal Carcinomatosis [60] Brain tumors A main challenge in the management of brain tumors lies in the localization of the extent of tumor and assessment of the functional ... role in diagnosis of prostate cancer mainly because of the low uptake of FDG in the tumor and normal excretion of FDG through urine Visualization of prostate cancer with current imaging methods...

Ngày tải lên: 09/08/2014, 09:22

... the data set better ( Pearson X statistics = 27.0 and 11.8 for degrees of freedom for purely fixed models) 4 DISCUSSION New perspectives are opened in the analysis of ordinal data by the use of ... Wright S., An analysis of variability in number of digits in an inbred strain of guinea pigs, Genetics 19 (1934) 506-536 [37] Wright S., The results of crosses between inbred strains of guinea pigs ... an approximation of the variance-covariance matrix One of the main advantages of this method is that it mimics the mixed model equations of Henderson [23] making the estimation of fixed effects...

Ngày tải lên: 09/08/2014, 18:21

... according to sex of calf (males, females) and age of dam at calving in years Scores and were pooled on account of the low frequency of score Nine levels were considered for age of dam: < years, ... records by sex-age of dam combinations is displayed in table I, as well as the frequencies of the three categories of calving scores The raw data reveal the usual pattern of highest calving difficulty ... dependency of the probabilities 77,! with respect to sex of calf and age of dam is not described properly by a model with constant variance Whether the poor fit of the S-TM is the result of ignoring...

Ngày tải lên: 09/08/2014, 18:22

... [45] The power of visualization There are a number of benefits of visual inspection of transcriptome data compared with statistical analyses, which we Second, visualized transcriptome data can reveal ... interpretation of complex datasets, such as those from transcriptome and proteome studies Additional data files The following additional data are available with the online version of this article: a list of ... genome of L lactis IL1403 (color file) (Additional data file 3); a table of cre-boxes identified in promoters of genes in the L lactis IL1403 genome (Additional data file 4) All additional data...

Ngày tải lên: 09/08/2014, 20:20

... pump protons out of the cytoplasm Here we identified homologs of five out of the six subunits of the V0 domain and six out of the eight subunits of the V1 domain known in yeast Many of these subunits ... EST clusters, and an analysis of these clusters compared to the KEGG database (Additional data file 9); an Excel-format spreadsheet detailing results of the search of Table of Quinn et al [44], ... % of KOG-assigned clusters Figure Distribution of clusters and reads by KOG functional class and library Distribution of clusters and reads by KOG functional class and library Distributions of...

Ngày tải lên: 09/08/2014, 20:20

... in Additional file 1) Page of To further compare the performance of the TMM normalization with previously used methods in the context of the DE analysis of RNA-seq data, we extend the above simulation ... study the effects of RNA composition on DE analysis of RNA-seq data To start, we simulate data from just two libraries We include parameters for the number of genes expressed uniquely to each sample, ... normalization of RNA-seq data Robinson and Oshlack Genome Biology 2010, 11:R25 http://genomebiology.com/2010/11/3/R25 Page of Figure Normalization is required for RNA-seq data Data from [6]...

Ngày tải lên: 09/08/2014, 20:21

... ‘ancestral’ genomes into blocks of different sizes, so that the genomes of the descendants of an Page of 18 admixture event are composed of different combinations of these ancestral blocks (Figure ... Predicted number of breakpoints per cM Page of 18 True number of breakpoints per cM Figure Performance of Hapmix and wavelet transform analysis in recovering the average number of recombination ... estimates of the time of admixture from suitable genome-wide SNP data We therefore applied the method to three datasets, consisting of about 650,000 SNPs, to estimate the amount and time of admixture...

Ngày tải lên: 09/08/2014, 22:23

... with a diagnosis of ACTH-dependent Cushing’s syndrome Magnetic resonance imaging (MRI) of her pituitary gland did not reveal the presence of an adenoma Localizing the source of excess ACTH secretion ... this time A repeat MRI of her pituitary gland once again did not reveal the presence of an adenoma Given the failure of biochemical or imaging techniques to localize the site of excess ACTH secretion, ... need for a combination of tests to help determine the cause of Cushing’s syndrome Furthermore, functional imaging may not always assist in localizing an anatomical site of excess ACTH secretion...

Ngày tải lên: 10/08/2014, 23:20

... Figure Properties of the set of 893 patterns Properties of the set of 893 patterns (a) Number of patterns with a given number of probe sets associated with a score of 90% (b) Number of patterns with ... Our analysis also suggests that the completion of the genomes of members of the Urochordata, Cephalochordata, Hyperoartia, and Chondrichthyes taxa will provide great insight into the evolution of ... functions in the analyses of other collections of gene expression data sampling multiple tissues Examination of markers of stem cell differentiation One distinctive feature of the gap method is that...

Ngày tải lên: 14/08/2014, 08:20

... Table II Accuracy of the estimates of the mixed HMM as a function of the level of response to infection, high (H) or moderate (M), number of samples per cow (T), percentage of cows with at least ... e; where y is the (NT ã 1) data vector of ytk , l0 and l1 are (T ã 1) vectors of xed effects for data on an IMI or IMI+ cow, respectively, a is the (Na ã 1) vector of random additive genetic ... the reported median time of rst occurrence of mastitis, i.e two to three months [6] 2.8.2 Evaluation of the accuracy of the estimates The estimates ^ti ; r2 ; r2 ; r2 ; aị of the parameters lti...

Ngày tải lên: 14/08/2014, 13:21

... experiment (data not shown) Discussion ChIPOTle is a Microsoft Excel macro that is designed for use in the analysis of data from ChIP-chip experiments ChIPOTle exploits the unique characteristics of ChIP-chip ... characteristics of ChIP-chip data, including enrichment of DNA genomically adjacent to sites of protein-DNA interaction, and the single-tailed nature of the data, to define peaks of enrichment and their ... Identification of ribosomal protein gene promoters as targets of Rap1p (a) Volume 6, Issue 11, Article R97 Figure Comparison of ChIPOTle with other ChIP-chip analysis approaches Comparison of ChIPOTle...

Ngày tải lên: 14/08/2014, 15:20

... 4.2 Process of Hidden Topic Analysis of Large-scale Vietnamese Datasets 37 4.2.1 Data Preparation 37 4.2.2 Data Preprocessing 37 4.3 Hidden Topic Analysis of VnExpress ... inference for new documents 4.2 Process of Hidden Topic Analysis of Large-scale Vietnamese Datasets 4.2.1 Data Preparation With the purpose of using a large scale dataset for Vietnamese contextual ... We then apply this method for topic analysis of a large scale Vietnamese dataset, VnExpress We examine the analysis of this dataset with different number of topics: 60, 120 and 200, which have...

Ngày tải lên: 20/08/2014, 09:36

... studies, data are collected on a repeatedly measured marker and a time-to-event outcome Longitudinal data and survival data are often associated in some ways Separate analysis of the two types of data ... 27 Table 2.3 NSABP B-14 data analysis based on general models 29 Table 2.4 NSABP B-22 data analysis using restricted models 34 Table 2.5 NSABP B-22 data analysis using general models ... computing and his installation of Stan in Linux server I also thank other colleagues of mine for their encouragement v Baoguang Han STATISTICAL ANALYSIS OF CLINICAL TRIAL DATA USING MONTE CARLO METHODS...

Ngày tải lên: 24/08/2014, 11:40

... ANALYSIS OF DOSE-RESPONSE DATA FROM DEVELOPMENTAL TOXICITY STUDIES PANG ZHEN (Master of Science, Beijing University of Technology) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... determination of an acceptable low-risk or safe dose level (Crump, 1984; Chen and Kodell, 1989; Ryan, 1992) 1.2 Special Features of Clustered Binary Data One of the classical hypotheses of the modelling of ... number of malformed fetuses within a litter Chapter 1: Introduction 1.3 Different Approaches The analysis of correlated binary data is less well developed than the case of correlated continuous data...

Ngày tải lên: 15/09/2015, 22:03

... effects of functional candidate genes on the quality of pork……… 37 3.2.1 The analysis of UBXN1…………………………………………… 37 v 3.2.2 The analysis of TRIP12…………………………………………… 37 3.2.3 The analysis of UBE3B…………………………………………… ... function of UBE3B results in the decreased of water holding capacity of pork 3.2.4 The analysis of ZRANB1 The OTU (ovarian tumor) domain of ZRANB1 removes ubiquitin signals from a major component of ... results in the decreased of inherent water retained in muscle cell at early post mortem 3.2 The effects of functional candidate genes on the quality of pork 3.2.1 The analysis of UBXN1 In the previous...

Ngày tải lên: 19/11/2015, 16:33