analysis in the time domain

... amino acids Those domains are the epimerization domain (E -domain) for Ca-epimerization [15], the methyltransferase domain (M -domain) for N-methylation [16] and the cyclization domain (Cy -domain) ... T- and E -domain) from the gramicidin S system and the ®rst module in the second peptide synthetase of the tyrocidine A system TycB1Pro-CAT (proline-activating module; C-, A-, and T -domain; see ... [5] Furthermore, a chromosomal point mutation in srfA-B, changing a D to A in the His-motif (italic) of the corresponding Asp domain of the surfactin synthetase was found to abolish surfactin production...

Ngày tải lên: 17/03/2014, 11:20

... binding site for either pyrroloquinoline quinone (PQQ) or NADPH In particular, AASDH, containing a PQQ binding domain, is supposed to be involved in lysine degradation and to convert the a-aminoadipate ... a-aminoadipate [12] Lys2, possessing a NADPH-binding domain, is involved in lysine biosynthesis; it converts the a-aminoadipate to a-aminoadipate semialdehyde [13,14] Furthermore, the protein ... adenylation domain, T for thiolation, C for condensation, AS for amine-selecting, PQQ for PQQ-binding domain, NADPH for NADPH-binding domain, X for other domains not commonly present in NRPSs Numeric...

Ngày tải lên: 23/03/2014, 13:20

... 2.2 Time- varying filtering Time- varying filtering is used in order to obtain watermark with specific time- frequency properties as well as to provide the inverse transform from the time- frequency domain ... inverse mapping from the time- frequency domain Additionally, a reliable procedure for blind watermark detection is provided by modifying the correlation detector in the time- frequency domain It is ... Advances in Signal Processing watermark according to these components The basic idea of this approach has been introduced in [12] The time- varying filtering is also used to overcome the problem of inverse...

Ngày tải lên: 21/06/2014, 22:20

... in Algeria during the 1960s and had gained increasing in uence during the 1980s Of their main leaders, one, Abbasi Madani, had participated in the initial attack on French rule in 1954, had then ... years, leaving the body vulnerable to other fatal diseases; a marked increase in those diseases, suggesting the presence of HIV, can first be observed in the main hospital in Kinshasa during the later ... rural earnings during the 1960s, they fell over 30 percent on average during the 1980s Yet employment was still a privilege, because the poor, hitherto mainly the incapacitated, now included the able-bodied...

Ngày tải lên: 01/11/2013, 07:20

... although the concentrations of these materials present in the artery wall, and in atherosclerotic lesions, are unknown The role of glycation and the two facets of glycoxidation in generating modified ... medium during the chase period allows the turnover of preaccumulated protein to be studied in the absence of further cellular uptake In these studies, cell death was < 12% as measured by the appearance ... CD36 The accumulation of lipid in these macrophages is accompanied by increased endocytosis and degradation of apoB, with the difference in the rates of the latter two processes resulting in accumulation...

Ngày tải lên: 19/02/2014, 02:20

... according to procedures described in [23] The capacity of daunorubicin and WP631 to produce cell death was determined by monitoring the decline in the number of cells originally cultured Cell viability ... AnnexinV-Fluos staining and low propidium-iodide staining are clearly more abundant after treatment with daunorubicin (D) Fig Quantitative determination of the uptake of daunorubicin and WP631 in ... WP631 in C,D), and the drug was mostly located inside the nuclei The unstained nucleoli can be observed not die by apoptosis in the presence of WP631, were actually sensitive to the treatment In...

Ngày tải lên: 20/02/2014, 23:20

... unfolding of some protein substrates is initiated through productive binding to the substrate via two elements in ClpA, one in the N -domain and the other in the pore of the ClpA hexamer In the ... N -domain and two ATP-binding domains referred to as the D1 and D2 domains Interestingly, deletion of the N -domain from ClpA not only abolishes binding of the adaptor protein, ClpS, but additionally ... residues in the N -domain In this case, it is appealing to speculate that ClpS itself may act as the second binding site required for unfolding, thereby replacing a need for the N -domain Experimental...

Ngày tải lên: 07/03/2014, 05:20

... seen in Fig 4, both proteins possess N-terminal AAA+ domains and C-terminal DNA binding domains (DBDs) In DnaA, the DBD contains a helix-turn-helix; in the archaeal proteins, the DBD has a winged ... are shown in cyan with ADP indicated in red The helix-turn-helix (HTH)-containing DNA binding domain of DnaA is in green and the winged helix (WH)-containing domain of Orc1 ⁄ Cdc6 is in dark blue ... helix domain (reviewed in [62]) Interestingly, the relative position of the AAA+ domain and the winged helix domain of Aeropyrum pernix Orc1 ⁄ Cdc6 homolog was in uenced by the nature of the nucleotide...

Ngày tải lên: 07/03/2014, 21:20

... chain to the nucleotide-binding pocket [3] We describe the engineering, expression and purification of single-cysteine-containing proteins comprising either the C-terminal NBD or the N-terminal ... N-terminal NBD of P-glycoprotein contains only a single cysteine in the Walker-A motif [43] Thus, MBP-NBD-Nter is a 75-kDa fusion protein containing a single cysteine residue located in the ATP-binding ... on p[NH]ppA binding, in agreement with the results obtained here The nonidentical interaction of GTP may be related to another variation in sequence in the vicinity of the ATP-binding pocket,...

Ngày tải lên: 08/03/2014, 08:20

... conformational change in a similar manner to NifA; the binding of the ATP analog induces the rearrangement of the GAF and possible AAA+ (the central domain) domains in VnfA Indeed, the limited protease ... of the N-terminal domain in this variant Because sensing is a principal function of regulatory proteins, the isolation of VnfA and AnfA with their sensor (GAF) domains is highly desirable In the ... position 107, at position 134 in the GAF domain and at position 267 in the possible AAA+ domain Accordingly, to determine which Cys are associated with the binding of the Fe-S cluster, we prepared...

Ngày tải lên: 15/03/2014, 09:20

... original NMR numbering for two -domain mammalian metallothionein (2, and are assigned to the three divalent metal ions in the b domain) [10,11] The 11 cysteinyl sulfurs are labeled according to the ... identification of the binding site for the fifth Cd2+ ion in the Cd5a-rhMT 1a cluster The indirect 2D 1H–113Cd NMR approach exploits the J scalar coupling between the cysteine b protons and the coordinated ... Cd4 binding site Finally, the NMR data verify the coordination of the fifth Cd2+ ion by thiolate ligands within the cluster, and, more specifically, within the crevice site of the protein The biological...

Ngày tải lên: 16/03/2014, 06:20

... have the PEST motif within the SH2 domain, while SOCS1, -5 and -7 contain PEST motifs in the N-terminal domain The PEST sequence in the CIS SH2 domain is located eight residues downstream from the ... phosphotyrosine–peptide binding [3] There is therefore some uncertainty about the extent of the SH2 domain, depending on whether it is predicted by sequence homology or functional analysis In addition ... peptide, including the predicted SH2 domain alone (44–142) This implied that the SH2 domain itself was a cause of poor solubility, as was the SOCS box The sequences of the SOCS3 SH2 domain and the...

Ngày tải lên: 16/03/2014, 14:20

... methods described in the thesis It is interesting to develop models and algorithms according to the nature of the data, instead of trying to adjust the data to the nature of the model In an attempt ... 1.1 INTRODUCTION The subject of this thesis is multi-way analysis The problems described mostly stem from the food industry This is not coincidental as the data analytical problems arising in the ... This monograph was originally written as a Ph D thesis (see end of file for original Dutch information printed in the thesis at this page) i MULTI-WAY ANALYSIS IN THE FOOD INDUSTRY Models, Algorithms...

Ngày tải lên: 31/03/2014, 22:20

... Roaming between the IMS and the CS CN domain refers to inter -domain roaming between IMS and CS When a user is not registered or reachable in one domain a session can be routed to the other domain ... network where the IMS introduces multimedia session control in the packet-switched domain and at the same time brings circuitswitched functionality in the packet-switched domain The IMS is a key ... that both the CS CN domain and the IMS domain have their own services and cannot be used from another domain Some services are similar and available in both domains (e.g., Voice over IP in IMS and...

Ngày tải lên: 05/04/2014, 23:31

... prosecution under the German Copyright Law Springer-Verlag is a company in the BertelsmannSpringer publishing group © Springer-Verlag Berlin Heidelberg 2000 Printed in Germany The use of general ... category Our main tool is, in some sense, integration by parts, which is equivalent to the fundamental theorem of the infinitesimal calculus In our direction there are two books One of them is HSrmander's ... Microlocal Analysis" in the space of hyperfunctions ( or in a rather wider class of functions) which makes it possible to apply the methods in the C °O_ distribution category to the studies on P.D.E in...

Ngày tải lên: 01/06/2014, 08:02

... 6.1.1.1 Inserting Zeroes in DWT Coeffcients 6.1.1.2 DCT Domain Upsampling in 2D 6.1.1.3 Upsampling the DCT for Multilevel DWT 6.1.1.4 Wavelet Synthesis in the Compressed Domain 6.1.1.5 ... processing in the domain of alternative representation is referred here as processing in the compressed domain However, we should also be concerned about the efficiency of the processing algorithm in ... Processing in the domain of Alternative Representation Output Image in the Compressed Form Entropy Encoding Processed Output in Alternative Representation Figure 1.3: Processing in the domain of...

Ngày tải lên: 05/06/2014, 12:04

... the same gait pattern (from kinematics and kinetics point of view) with the same gait speed These trials were considered for the following analysis The data were considered repeatable according ... in respect to the walking direction and is defined as the angle formed with the line of progression and the segment connecting the marker on the V metatarsal joint and the marker on external ... both to the subject's weight and to the walking velocity were calculated as kinetic parameters in order to investigate the push-off ability during the propulsive phase of the gait cycle (terminal...

Ngày tải lên: 19/06/2014, 10:20

... glycosylation These findings are intriguing given that these three cysteine residues are absolutely conserved not only in the F proteins of other Pneumovirinae, but also in the F proteins of the Paramyxovirinae ... cysteine residues in the extracellular domain in protein expression and cell fusion of the HRSV F protein and represents the first analysis of the contribution of the cysteine residues of the ... by an intervening cysteine-rich region A hydrophobic transmembrane domain is located near the C-terminus of the protein followed by a short (26 residues) cytoplasmic domain containing a single...

Ngày tải lên: 20/06/2014, 01:20

... channels (MAC) [13] The work in [5] uses error statistics for the sum-capacity-optimal dirty-paper coding (DPC)[1] to determine when time- sharing outperforms DPC in the multiple-input single-output ... 20] However, since these models may not capture the complex physical structure of the multiuser time- variant MIMO channel [21], the results obtained using the models are reinforced using simulations ... on a time scale larger than the channel coherence time, and therefore values of N are chosen to remain within the channel stationarity time The test equipment at BYU allows sampling of a singleuser...

Ngày tải lên: 22/06/2014, 00:20

... Institute in the Philippines and the University of Sydney The proposal for courses in the areas of marketing and policy analysis grew out of the experience in providing training as indicated above The ... used in capacity building with particular emphasis on ‘training the trainers’ Over the period of the project there has been a significant shift in the material used in teaching programs and in the ... clear indications of the benefit of the training in the work being undertaken and the level of analysis used for Ministry projects It is considered that over the period of the program there has...

Ngày tải lên: 22/06/2014, 13:20