an integrative model of drug transport in mdr cells
Summary of doctoral thesis: Research on management model of public transport in Viet Nam cities
... definitions of urban transport, public transport and its roles in urban sustainable development; then systematizing the theories of public transport management and organizational model in management, ... for state management in urban public transport 1.3.1 Overview of state management in urban transport The nature of state management in urban area is an intervention of Government in urban socio-economic ... State management in urban public transport Main functions of state management in urban public transport: - Orienting strategies of public transport development in corresponding with general transport...
- 27
- 589
- 0
báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
... previously analyzed, including LPS and LBP plasma concentrations and TLR4 and MD-2 expression and mRNA levels In this vein, of special relevance is the finding that antibiotic intestinal decontamination ... the brain (A) Brain levels of the pro-inflammatory prostaglandin PGE2 (B), the anti-inflammatory one 15d-PGJ2 (C), and interleukin-1b (IL-1b) mRNA levels in control and after CMS in the brain (D) ... exposed to an animal model of depression This activation occurs with increased levels of the pro-inflammatory cytokine IL-1b and of one of the main enzymatic sources of inflammatory and oxidative...
- 14
- 422
- 0
Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx
... Blotting for biglycan identified intact core protein (43 kDa) and a number of fragments (39, 32, 28 and 26 kDa) in all of the specimens There was an increase in staining intensity for all biglycan ... Beavan L, Kresse H: Decorin-type I collagen interaction Presence of separate core protein-binding domains J Biol Chem 1995, 270:8877-8883 Hedbom E, Heinegard D: Binding of fibromodulin and decorin ... reported in both human OA [20] and spontaneous canine OA [52], but not in a canine cruciate ligament transection model of OA [52] The catabolites that were identified in meniscectomized cartilage in...
- 10
- 416
- 0
Báo cáo y học: "Cardiorespiratory effects of venous lipid micro embolization in an experimental model of mediastinal shed blood reinfusion" pptx
... 4:48 maintenance of anesthesia were achieved using an infusion of 0.15 mg/kg/min ketamine chloride and 0.01 mg/ kg/min pancuronium bromide (Pavulon®, N.V Organon, Oss, the Netherlands), or an infusion ... line indicates the infusion of shed blood surrogate The second dashed line indicates the infusion of epinephrine and Ringer's lactate return completely to baseline until after the infusion of ... pharmacologically increased blood flow and pressure After infusion of epinephrine and Ringer's lactate an increase in arterial blood pressure ensued (Figure 2), as shown by a significant increase in the AUC of...
- 9
- 362
- 0
Báo cáo y học: " Adjuncts or adversaries to shared decision-making? Applying the Integrative Model of behavior to the role and design of decision support interventions in healthcare interactions" pps
... a redefinition of the role of patients in decision-making This new conceptualization of the role of patients in decision-making in healthcare settings is often termed 'shared decisionmaking' [1-3] ... http://www.implementationscience.com/content/4/1/73 Advancing DESI research We believe that a substantial barrier to advances in implementing shared decision-making in routine clinical care settings is the lack of theoretical and conceptual ... conceptual definitions of shared decision-making and distilled these works into a proposed model of shared clinical decision-making [27] In formulating this model, the authors distinguished between...
- 10
- 412
- 0
báo cáo khoa học: " Adjuncts or adversaries to shared decision-making? Applying the Integrative Model of behavior to the role and design of decision support interventions in healthcare interactions" doc
... a redefinition of the role of patients in decision-making This new conceptualization of the role of patients in decision-making in healthcare settings is often termed 'shared decisionmaking' [1-3] ... http://www.implementationscience.com/content/4/1/73 Advancing DESI research We believe that a substantial barrier to advances in implementing shared decision-making in routine clinical care settings is the lack of theoretical and conceptual ... conceptual definitions of shared decision-making and distilled these works into a proposed model of shared clinical decision-making [27] In formulating this model, the authors distinguished between...
- 10
- 410
- 0
Báo cáo y học: "The laminin b1-competing peptide YIGSR induces a hypercontractile, hypoproliferative airway smooth muscle phenotype in an animal model of allergic asthma" potx
... contains the RGD-binding motif present in ECM proteins like fibronectin, collagens and laminins [24,25] The specific role of laminins in ASM remodelling in vivo, however, remains to be determined ... epithelial integrity show increased laminin g2 chain expression in the airways [19] Laminins appear to be essential for lung development and are important determinants of ASM function Laminin a1 and ... Therefore, using a guinea pig model of chronic asthma, we explored the role of laminins in ASM remodelling in vivo, by treating the animals with the specific soluble laminin-competing peptide...
- 11
- 253
- 0
Báo cáo y học: " Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury" doc
... bleomycin injection in WT mice, positive staining for IL-1 (A) was localized mainly in inflammatory cells and in vascular endothelium There was a marked reduction in the IL-1 immunostaining in the ... accumulation of water in lung as an indicator of lung edema, (Fig 1f) and neutrophils infiltration in the lung tissues in WT-animals The leukotrienes synthesis inhibition and the receptor blockade in bleomycin ... immunostaining in the lungs of MK-571 group (B) and in the lungs of Zileuton group (C) TNF-α was localized mainly in inflammatory cells and in bronchial epithelium of lungs in the bleomycin group (E) A marked...
- 12
- 265
- 0
Báo cáo y học: "Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain" doc
... shows that longterm antinociceptive effects of HA preparations can be assessed in an animal model of joint pain based on the repeated intra-articular injection of bradykinin and PGE2 Boettger ... applicable and significant change in pain-related behavior as assessed employing different methods (see effects of saline and morphine injections) Although in principle, such models, mainly using bradykinin ... treatment of OA Here we report on the magnitude and long-term duration of antinociceptive effects of NASHA and other HA preparations in the bradykinin/PGE model of repetitive joint pain Materials and...
- 11
- 357
- 0
Báo cáo y học: "Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis" pps
... endotoxin injection in normal subjects J Clin Endocrinol Metab 1994, 79:1605-1608 35 Becker KL, Whang KT, Snider RH, et al: Relation between cytokines and procalcitonin peptides in an animal model of ... inflammation and sepsis References American College of Chest Physicians — Society of Critical Care Consensus Conference: Definitions of sepsis and organ failure and guidelines for the use of innovative ... as an index of inhalation injury in burns Horm Metab Res 1992, 24:439–443 12 Assicot M, Gendrel D, Carsin H, et al: High serum calcitonin concentrations in patients with sepsis and infection Lancet...
- 6
- 488
- 0
Báo cáo y học: "A mechanism of airway injury in an epithelial model of mucociliary clearance" doc
... de-staining in 20% isopropanol in 4% ethanol and 8% acetic acid The presence of gelatinases (MMP and 9) was shown by clear bands (no staining) corresponding to MMP standards (MMP and 9) run in leftmost ... site of action of the MMPs and a source of MMPs in this model will be important to determine the mechanism of action of this effect How MMPs are activated in the tissue is another important question ... have been shown to play a role in airway injury and remodeling [7,8] and in cellsignaling pathways [14] Materials and Methods Development of a frog palate injury model A fresh frog palate was...
- 9
- 301
- 0
Báo cáo y học: "Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome" potx
... Crs and PaO2 evolution in an experimental model of ARDS during a reversed sequential ramp procedure of PEEP changes to investigate the potential interest of combining FRC and Crs measurements in ... combination of FRC and Crs measurements obtained in this porcine model of ARDS may help to identify the optimal level of PEEP Indeed, by taking into account the value of both parameters, during ... of ventilator induced lung injury [10] Increasing the level of PEEP can be more harmful than beneficial since it will serve also to increase inflation of lung regions that are already open, increasing...
- 6
- 275
- 0
Báo cáo y học: " Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension" ppt
... underwent inhalation of placebo (5 ml isotonic saline solution) In a subsequent study, including 10 pigs, the effects of inhaled iloprost (Ilomedin®; Schering Deutschland GmbH, Berlin, Germany; 50 ... mg/kg) and atropine (0.5 mg), anaesthesia was induced with intravenous sodium pentobarbital (12 mg/kg) After endotracheal intubation, anaesthesia was maintained with a continuous intravenous infusion ... administered at a rate of ml/kg per hour Normothermia was maintained during the entire procedure using an infrared heating lamp A 7.5-Fr central venous catheter was inserted into the femoral vein...
- 13
- 231
- 0
Báo cáo y học: "Hepatic oxidative stress in an animal model of sleep apnoea: effects of different duration of exposure" potx
... ischemia-reperfusion [18] in which there is activation of xanthine oxidase, leading to the formation free radicals and further imbalance between oxidants and antioxidants [4-6] The analysis of liver integrity ... exposed to intermittent hypoxia compared to SIH, demonstrating a reduced hepatic antioxidant defence in these animals The increase in TBARS and decrease in endogenous antioxidants observed in the ... livers of IH-35 mice confirms findings by other authors, who demonstrated a significant increase of nitric oxide in animals exposed to IH simulating OSA (6 min/6 min) during 120 days [48], and to...
- 7
- 281
- 0
Báo cáo y học: "Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis" ppsx
... experiments, and analysed and interpreted the data KB contributed in the performance, analysis and interpretation of immunoblotting assays DLT contributed with grant support, study design and interpretation ... suspended in 30 mL of saline Using a bronchoscope (model FB-19H; Pentax, Japan), the solution was injected into the right lower, right middle and left lower lobes Anaesthesia was then discontinued and ... Traber D: Methicillin-resistant Staphylococcus aureus-induced sepsis: role of nitric oxide In Yearbook of Intensive Care and Emergency Medicine Edited by: Vincent JL Berlin: Springer; 2008:404-12...
- 9
- 372
- 0
Báo cáo y học: " Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis" ppsx
... and antiinflammatory cytokines, decreasing CINC-1 and IL-6 in BALF and PLF at 18 hours, and increasing IL-10 in PLF at 18 hours and BALF at 48 hours We used a CLP model of sepsis for the following ... reduced pro-inflammatory cytokines (CINC-1 and IL-6) with an increase in anti-inflammatory cytokine (IL-10) in BALF and PLF (Figure 7) It has been reported that CINC-1 plays an important role in the ... macrophage inflammatory protein-2 On the other hand, the lack of endogenous IL-10, a prototypic anti-inflammatory cytokine, resulted in increased levels of TNF and enhanced mortality in mouse models of...
- 11
- 397
- 0
Báo cáo y học: "Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathwa" ppt
... creatinine at t = 180 minutes (b) Creatinine clearance was measured over t = 120 minutes to t = 180 minutes Creatinine clearance = UCr × V/PCr, where UCr represents the creatinine concentration in ... attenuates VILI and renal hypoperfusion and dysfunction, by maintaining endotheliumdependent vasodilation and decreasing inflammation and tissue injury, in the rat kidney during LPS-induced lung injury ... creatinine, and urea (Modular Analytics, Roche Diagnostics, Mannheim, Germany) In rats with preserved urinary production, creatinine clearance was calculated using the formula UCr × V/PCr In this...
- 10
- 398
- 0
Designing quality management model of passenger transport service by railway in vietnam
... and passenger transport) Figure 2.1 Business model of railway transport service in Vietnam The separation of business management of transport service components creates autonomy in business and ... system of passenger transport quality by railway”, Journal of Transport No 9/2014 PhD Hoang Van Lam (2016), “Quality chain model of passenger transport service by railway”, Bulletin of Transport ... in January 2012 PhD Hoang Van Lam (2013), “Analysis of quality forming elements of passenger transport by railway”, Journal of Transport No 7/2013 PhD Hoang Van Lam (2014), “Construction of indicator...
- 14
- 277
- 0
CFD model of air movement in ventilated façade: comparison between natural and forced air flow
... in winter and guarantee passive cooling effect by combining convective and heat transport between the outer and inner walls in summer; watertight to guarantee no water infiltration due to rain, ... broad range of operating conditions The advantage of using these models lies in the fact that they can reproduce real problems of Fluid Mechanics to any degree of complexity Furthermore, they can ... approaches used in predicting building ventilation including analytical models, empirical models, multizone models, zonal models, experimental models and computational fluid dynamics (CFD) models [2]...
- 12
- 506
- 0
Gián án A STUDY OF STRUCTURAL BREAKS IN MALAYSIAN STOCK MARKET
... (1990) Analysis of time series subject to changes in regime Journal of Econometrics, 45: 39–70 Hamilton, J D (1993) Estimation, inference and forecasting of time series subject to changes in regime ... representation IEEE Trans Pattern Anal.Machine Learn 11(9): 674-693 Resnikoff, H L and Wells, R O (1998) Wavelets Analysis: A Scalable Structure of Information Springer-Verlag, New York Strang, G and Nguyen, ... Denoising Non-Stationary Time Series using Daubechies Wavelets.Seminar Kebangsaan Matematik & Masyarakat (SKMM), UMT Terengganu 13-14 February 2008, Grand Continental Hotel, Kuala Terengganu (In...
- 19
- 490
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25