an emerging tool to characterize the molecular heterogeneity of breast cancer
Báo cáo khoa học: Immunonanoparticles ) an effective tool to impair harmful proteolysis in invasive breast tumor cells docx
Ngày tải lên :
23/03/2014, 07:20
... resonance To confirm the binding of anti-cytokeratin monoclonal IgG to the nanoparticles, the nanoparticles were tested for their interaction with protein A, immobilized onto the surface of an SA ... lysosomes Furthermore, the labeling of nanoparticles with anti-cytokeratin monoclonal IgG provides specific delivery of nanoparticles to the epithelial breast cancer cells humanized analogue has ... agent to bind to the tumor cell surface and to trigger receptor-dependent endocytosis resulting in the delivery of the therapeutic agent to the endosomes and lysosomes Polymeric nanoparticles themselves...
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Báo cáo khoa học: "The use of crossreactive monoclonal antibodies to characterize the immune system of the water buffalo (Bubalus bubalis)" pdf
Ngày tải lên :
07/08/2014, 15:20
... Perryman, L E., McGuire, T C and Gorham, J R The The use of crossreactive monoclonal antibodies to characterize the immune system of the water buffalo (Bubalus bubalis) development and analysis of ... specific and cross reactive monoclonal antibodies to leukocyte differentiation antigens and antigens of the major histocompatibility complex for use in the study of the immune system in cattle and other ... leukocytes in the water buffalo These mAbs have provided an opportunity to characterize and compare the immune systems of cattle and water buffalo Materials and Methods Animals: Four adult and four...
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Báo cáo y học: "Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity" potx
Ngày tải lên :
14/08/2014, 08:20
... and methods sufficient protein may contribute to the intrinsic resistance of the cell to the toxic action of the metal Over-representation of specific Gene Ontology terms in the annotations of ... Size of growth effect Figure of Analysis the global effects of Cr treatment on the heterozygous mutants Analysis of the global effects of Cr treatment on the heterozygous mutants The plot shows the ... as models to further our understanding of cellular metal toxicology, and because of the importance of metal toxicity in microbial biotechnologies [4-7] Chromium toxicity is an issue of especially...
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Báo cáo y học: "The molecular basis of lung cancer: molecular abnormalities and therapeutic implications" potx
Ngày tải lên :
12/08/2014, 18:21
... changes are seen in the transition from normal to intraepithelial cancer to invasive disease The understanding of the timing of instability during progression, the rate of instability and the ... exposure of the whole airway mucosa to tobacco smoke could cause the entire bronchial tree to be at increased risk of developing lung cancer, leading to the concept of field cancerization Field cancerization ... deletions as the mechanism of loss of p16 function [27] The relationship between tobacco and the loss of p16 points to new mechanisms involving smoking in the pathogenesis of lung cancer Mutagens...
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Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer pptx
Ngày tải lên :
05/03/2014, 12:20
... scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress ... breast cancer The committee recognized the need for research on the natural history of breast cancer to more clearly define the significance of early lesions, the need for the development of biomarkers, ... to be devoted to the development and refining of technologies for the early detection of breast cancer The purpose of the study described in this report was to review the breast cancer detection...
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Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps
Ngày tải lên :
09/08/2014, 03:21
... Society of Mastology (EUSOMA) and Europa Donna, the innovative concept for standard guidelines of Breast Units has been proposed to assure the best quality of care to women with breast cancer The ... organization for the treatment of breast cancer This change will be driven not much from mandatory requirements, but by the willingness of more sophisticated breast cancer patients to search for the most ... surgery and postoperative radiotherapy J Clin Oncol 1999, 17:101-109 63 Early Breast Cancer Trialists Collaborative Group: Effect of radiotherapy and surgery in early breast cancer An overview of the...
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Báo cáo khoa học: "Ruptured gallbladder as the first presentation of breast cancer" docx
Ngày tải lên :
09/08/2014, 04:21
... cervical cancer, lung cancer, and breast cancers [8] Figure peritoneum CT abdomen showing air in the biliary tree and free air in the CT abdomen showing air in the biliary tree and free air in the ... Lobular cancers of the breast are well known to metastasise to the gastrointestinal tract compared to ductal cancers, and metastasis to the gallbladder has previously been reported [2-4] Mechanism ... breast carcinoma (bottom left) infiltrating the neck of the gallbladder (top right) MJ wrote the report JM revised and submitted the report for publication KLC conceived the idea and edited the...
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Báo cáo y học: " Using an Ishikawa diagram as a tool to assist memory and retrieval of relevant medical cases from the medical literature" ppt
Ngày tải lên :
11/08/2014, 00:23
... would then be reviewed to extract relevant causes in the context of the main presenting problem These causes would then be organized in the ‘fish bones’ of an Ishikawa diagram (Figure 1) There ... students and junior doctors to identify the main presenting problem of a patient, conduct brainstorming sessions and search in the literature to find the potential causes, then categorize these ... memory and the retrieval of relevant medical case reports and literatures Acknowledgements I would like to thank the Journal of Medical Case Reports and BMJ Case Reports for providing access to the...
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Báo cáo y học: "An innovative method to evaluate the suture compliance in sealing the surgical wound lip"
Ngày tải lên :
03/11/2012, 11:52
... at the crooked (anchor) arms of the dynamometer The distance between the crooks was 30 ± mm (the optimal distance preventing interference), and the velocity was 50mm/sec The test ends at the ... horizontal plane (one drop over one centimeter of the incision line released from a height of 0.5 cm) This is to evaluate the permeability of each suture on the basis of the uptake of the stain by the ... available, and the surgeon can choose from a list of suture threads with a range of attributes to find the one best suited to the particular needs of the wound in question When choosing an appropriate...
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Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc
Ngày tải lên :
19/02/2014, 17:20
... to placing all the genes involved in the pathway in the same operon; the cell can then respond quickly to changes in the environment by changing the expression of only a few genes and using the ... by the Danish Dairy Research Foundation (Danish Dairy Board), the Danish Research Agency and the Danish Center for Advance Food Studies (LMC) 2301 Control analysis of the las operon B Koebmann ... almost cancel each other out may also add to the explanation of why the genes are organized in an operon in L lactis When L lactis needs to up- or down-regulate the glycolytic flux it can so without...
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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
Ngày tải lên :
21/02/2014, 03:20
... conformational changes on the surface On the other hand, anionic surfactants such as SDS and LAS bind to the surface regions of protein, and the surface regions would be unfolded and removed from the core ... wild-type ALP I On the other hand, the Tm of D266N/Y269A-ALP I increased by only °C The denaturation temperature indicates the stability of the structure of the protein The difference of the increments ... structural change of the molecular surface would be unlikely to occur The mutation of Tyr269 to Ala caused the disappearance of a large aromatic polarized side chain projecting to solvent, and the surface...
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Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf
Ngày tải lên :
16/03/2014, 05:20
... leading to build-up of NADH, which was not expected, as the levels of cofactor should be sufficient to sustain the lactate flux Therefore, there must be an additional factor acting as an inhibitor of ... lactate, the activity of LDHB was 86% of the value determined in the absence of lactate, and at 300 mm lactate, the activity of LDHB was only 24% of the same control value Characterization of glucose ... interpolations the impact of these lactacte dehydrogenase features on the physiology of the organism The metabolism of glucose was monitored by in vivo 13C-NMR under 5928 anaerobic conditions Cells of strain...
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Báo cáo " Using multi‐criteria analysis as a tool to select the feasible measures for sustainable development of brackish water shrimp culture in Quang Tri Province " doc
Ngày tải lên :
22/03/2014, 12:20
... they can eat and giving them too many antibiotics. The excess of these substances will remain in the water and will also get in the sludge on the bottom of the shrimp ponds. By reducing the ... in the future, when the province has the plan to develop the aquaculture to be the key sector of local economics [6]. A re a (h e c ta r s ) January and accounts for 75% to 85% of ... Based on the constraints and objectives of the problem and the relating sectors, the measures or combinations of measures to solve the problem is to be suggested. These measures can be the ones ...
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ENFORCING THE COMMUNITY REINVESTMENT ACT: AN ADVOCATEíS GUIDE TO MAKING THE CRA WORK FOR COMMUNITIES pdf
Ngày tải lên :
22/03/2014, 20:21
... contain the name of the bank, a description of the proposed transaction, notice of the opportunity to comment, the name and address of the bank’s agency for filing comments, the availability of the ... the lending and other business practices of a bank Among the indicators relating to the financial health of a bank are the bank’s net income as a percentage of average assets and the bank’s risked-based ... percentage of the bank’s total loans and total dollar amount of loans within the bank’s CRA assessment area; the percentage of the bank’s loans to persons at low-, moderate-, middle-, and high-income...
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hack the stack - using snort & ethereal to master the 8 layers of an insecure network
Ngày tải lên :
25/03/2014, 11:19
... Anyone can use a tool, but to understand what the tool does and how it works allows for a higher level of learning Q: Why you list Ethereal as one of the most important tools a security professional ... before using any of these tools, which will save you from many headaches and potential legal problems Tools of the Trade The following sections examine “protocol analyzers” and the Intrusion ... 20 and 21 and is used to move files from one computer to another Port 20 is used for the data stream, and transfers the data between the client and the server Port 21 is the control stream, and...
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báo cáo hóa học: " An exploratory study to evaluate the utility of an adapted Mother Generated Index (MGI) in assessment of postpartum quality of life in India" potx
Ngày tải lên :
18/06/2014, 19:20
... department of Sitaram Bhartia Institute as a preparatory step prior to the survey These involved asking the mothers to identify the most important positive and negative areas of their lives and to rate ... number of areas identified to six, to keep the scoring points at 10, to allow 12 spending points and to allow the mother and child counselors to administer the index if requested by the subject To ... subject was reviewed and it was decided to adapt the index to the Indian setting, possibly at the expense of limiting its comparability to other settings In an attempt to keep the index as simple...
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báo cáo hóa học: " A tool to measure the attributes of receiving IV therapy in a home versus hospital setting: the Multiple Sclerosis Relapse Management Scale (MSRMS)" pot
Ngày tải lên :
20/06/2014, 15:20
... each scale had similar mean scores and standard deviations implying that they contribute equally to the variance of the total score, and can be summed without weighting Item-total scale correlations ... substantial (r > 0.30) item-total correlations [14] Targeting Scores span the full scale range [15] Mean scores near the midpoint [16] Floor and ceiling effects (endorsement at the bottom and the ... compared the psychometric properties of the MSRMS in the two independent samples (Stage and Stage 3) to enable us to comment on the stability of the instrument Analyses We re-examined the same...
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Báo cáo hóa học: " Research Article An Alternative Method to Compute the Bit Error Probability of Modulation Schemes Subject to Nakagami-m Fading" pdf
Ngày tải lên :
21/06/2014, 08:20
... is devoted to the derivation of an exact expression for the BEP of an M-PAM subject to Nakagami-m fading, while Section deals with the derivation of an exact expression for the BEP of the I × J-QAM ... presents the system model Section addresses the derivation of the CDF of the additive noise In Section 4, the CDF is used to derive an exact expression for the BEP of M-QAM subject to Nakagami-m ... the fact that a signal received from a fading channel is subject to a multiplicative distortion (MD) and to the usual additive noise—then, following a compensation of the MD, the signal fed to...
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Báo cáo khoa học: "An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korea" docx
Ngày tải lên :
07/08/2014, 20:23
... site located on the right edge of the receptor binding pocket [11] Many studies have demonstrated that the addition of oligosaccharides to the HA molecule changes the antigenicity of the virus [1,6,24,28] ... According to the 2004 Avian influenza standard operating procedures, Korean animal health authorities permitted the use of the vaccine for LPAI (especially the H9N2 subtype), and the Committee on the ... such changes exclusively affect the high growth trait of the vaccine virus Further studies would be needed to clarify the mechanism for the modification of this trait of the vaccine virus as the...
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