an easily ignored problem in dialysis patients with hyperparathyroidism

... Gemcitabine (2,2'-difluorodesoxycytidine) is a pyrimidine analogue with activity against a wide range of solid tumours, including pancreatic carcinoma and non small cell lung carcinoma [11] Its mechanism ... chemotherapy of oxaliplatin with/ without gemcitabine In the majority of cases oxaliplatin and gemcitabine were administered as combination therapy (n = 25 patients vs patients with oxaliplatin monotherapy; ... oxaliplatin in combination with gemcitabine or as a monotherapy in patients with MPM who were preteated with a pemetrexed/platin-combination therapy Pretreatment evaluation All patients underwent an...

Ngày tải lên: 20/06/2014, 00:20

... ng/ml was accepted as an elevated LP-PLA2 [24] Total Antioxidant Capacity Total antioxidant capacity in patients was determined with Antioxidant Assay Kit (Cayman Chemical Company, USA) The assay ... a minimum of 10 sec, was considered as hypopnea Individuals with an apnea hypopnea index (AHI) >5 were diagnosed as OSAS and included in the study Determining of Arousals An arousal was defined ... arousal index was associated with increased LP-PLA2 level The elevated levels of circulating LP-PLA2 may explain prone to sudden death due stroke and AMI in patients with OSA and increased arousal index...

Ngày tải lên: 25/10/2012, 11:00

... 306 were investigated in ESCC patients treated with a definitive 5-FU/CDDP-based CRT Patients and Methods Patients Fifty-six ESCC patients were enrolled in this study based on the following criteria: ... summarized in Table In the CDDP group, the plasma concentrations of 5-FU were significantly higher in the patients with CR than those with non-CR (P

Ngày tải lên: 26/10/2012, 09:53

... epithelial ovarian cancer, any stage borderline ovarian tumors with no invasive implants, SCSTs and MOGCTs (malignant ovarian germ cell tumors), even in the case of advanced germ cell disease, ... sparing in young women with ovarian tumors Clin Exp Obstet Gynecol, 37, 290-4 Gotlieb WH, Beiner MR, Shalmon B, et al (2003) Outcome of fertility sparing treatment with progestin in young patients ... issues in young women with breat cancer J Clin Oncol, 22, 4174-83 Parkin DM, Pisani P, Ferlay J, et al (1999) Global cancer statistics CA Cancer J Clin, 49, 33-64 Plante M, Renaud M.C, Francois...

Ngày tải lên: 22/03/2014, 11:20

... polymorphic genes coding for cytokines or for cytokine receptors have been investigated in a case control study including a group of 40 Iranian PTB patients and 40 healthy individuals 126 IJI ... found In conclusion it is suggested that pro inflammatory cytokines and TGF-¾ decrease in PTB patients, however further studies with a larger sample size for better understanding of cytokine gene ... was investigated in 110 healthy control and 101 tuberculosis patients by Niimi et al They did not find any significant differences between TGF-¾ genotypes of healthy controls and tuberculosis patients...

Ngày tải lên: 22/03/2014, 18:20

... Osteopontin and osteopontin-like gene and protein structure (A) Structural organization of osteopontin-like (tetraodon and zebrafish) and osteopontin (chicken, bovine, mouse and human) coding sequences ... aminoacid transmembrane signal peptide at the N-terminus for protein secretion, (b) an integrin receptor-binding RGD motif [arginine (Arg) 178–glycine(Gly)179– aspartic acid(Asp)180], suggesting a ... proteins involved in a wide range of cell mechanisms, including regulation of ECM mineralization (n ¼ 1), cellular metabolism (n ¼ 8) and cell organization and biogenesis (n ¼ 2) The remaining...

Ngày tải lên: 23/03/2014, 07:20

... observed between patients with and without septic shock, with increased sFlt-1 concentrations in patients with septic shock (116.0 pg/ml, range 42.7-208.4 pg/ml) compared to patients with non-complicated ... Figure Serum sFlt-1 and VEGF-A levels in FN Serum sFlt-1 and VEGF-A levels in patients with FN Box plots representing serial concentrations of sFlt-1 and VEGF-A in patients with FN with non-complicated ... onset with scores at the time of fever onset was not assessed Figure sFlt-1 and VEGF-A levels in patients with FN Combined analysis sFlt-1 and VEGF-A levels in patients with FN Actual sFlt-1 and...

Ngày tải lên: 18/06/2014, 19:20

... concentrations in the CSF and saliva of MS patients were further analyzed by subgrouping them into those with enhancing lesions vs those without enhancing lesions on brain MRI, with the understanding that ... those without enhancing plaques in their brain MRI scans Hybridoma cell lines W6/32 (anti-HLA-A, B, C), L368 (anti-human B2-microglobulin), Ab2.06, L203 and IVA12 (anti-HLA-DR) were obtained from ... sHLA-I, and an increase in CSF sHLA-I, but not CSF sHLA-II concentrations, in patients with MS [12,13] However, an elevation of CSF sHLA II and I as well as an increase in serum sHLAI, but not in...

Ngày tải lên: 19/06/2014, 22:20

... observed between patients with and without septic shock, with increased sFlt-1 concentrations in patients with septic shock (116.0 pg/ml, range 42.7-208.4 pg/ml) compared to patients with non-complicated ... Figure Serum sFlt-1 and VEGF-A levels in FN Serum sFlt-1 and VEGF-A levels in patients with FN Box plots representing serial concentrations of sFlt-1 and VEGF-A in patients with FN with non-complicated ... onset with scores at the time of fever onset was not assessed Figure sFlt-1 and VEGF-A levels in patients with FN Combined analysis sFlt-1 and VEGF-A levels in patients with FN Actual sFlt-1 and...

Ngày tải lên: 20/06/2014, 03:20

... of Japan [25] At time of sampling, disease was active in 15 patients and inactive in 10 All patients were using colchicine, an immunosuppressant agent such as ciclosporin (n = 8), azathioprine ... increased in Behçet’s disease [23] In this regard, we examined the expression of TNF-α and IL-12 receptors on Vγ9/Vδ2 T cells before and after inducing their expansion Materials and methods Patients ... were obtained Monoclonal antibodies and flow cytometry mAbs specific for human surface antigens anti-CD3 phycoerythrin-labelled (PE) and anti-T-cell receptor (TCR) Vδ2 fluorescein isothiocyanate...

Ngày tải lên: 09/08/2014, 01:23

... evaluate, in a cohort of consecutive patients with chronic HCV infection, whether anti-CCP antibodies are useful in distinguishing between patients with HCV-related arthropathy and patients with RA ... comprising patients without articular involvement (31 patients) To compare the prevalence of anti-CCP antibodies in HCV patients with that in patients affected by RA we enrolled 30 consecutive in- patients ... can be useful in differential diagnosis with RA Differentiating between patients with RA and those with HCV-related arthropathy has great relevance in clinical practice In fact, in contrast with...

Ngày tải lên: 09/08/2014, 01:23

... circulating IL-6 and midkine, independently of the patients weight status, and with Il-1, Il-8 and VEGF in cachectic cancer patients TNF-a, IL-1 and IL-6 are key cytokines involved in cancer-related ... and in a cohort of male patients with mainly lung and prostate cancer [27] Leptin is another member of the adipo-cytokines family It is produced mainly by differentiated adipocytes and acts in ... food intake and stimulator of energy consumption [12] Leptin plasma levels are reported to be higher in anorexia nervosa patients [28], but lower in gastrointestinal [29], and pancreatic cancer patients...

Ngày tải lên: 09/08/2014, 03:22

... of antiCCP antibodies and HLA-DRB1 has been described [6,11,13,19], indicating the importance of antigen presentation in the induction of autoimmunity This finding clearly could be confirmed in ... of PADI4: relevance for rheumatoid arthritis-specific synovial intracellular citrullinated proteins and anti-citrullinated protein antibodies Ann Rheum Dis 2005, 64:1316-1320 Martinez A, Valdivia ... approach [8] Importantly, three novel coding SNPs in exons 2, 3, and and three SNPs in introns and located near the exon–intron boundaries were found in 11/102 individuals (10.8%) Moreover, a closely...

Ngày tải lên: 09/08/2014, 07:20

... study and performed statistical analysis KN and KT participated in coordination and interpretation of data PL participated in acquisition of data and helped in drafting and revising the manuscript ... been involved in drafting and revising the manuscript for important intellectual content and have given final approval of the version to be published All authors read and approved the final manuscript ... variations and clinical manifestations or laboratory profiles In our study, the BB genotype is low in both 194 healthy controls and 101 patients with SLE However, this is in accordance with previous findings...

Ngày tải lên: 09/08/2014, 07:20

... presenting clinical findings of patients with suspected GCA at baseline Studies in control subjects and follow-up examinations were performed in an unblinded manner A high-resolution linear array ... study and the clinical follow-up SP participated in the coordination of the study and performed CDS M Kanakis helped in the clinical follow-up and in the analysis and interpretation of the data and ... diagnosed with GCA within a mean of 22 days after initiation of corticosteroid treatment In nine of these patients, halos were not detectable at the 2-week time point, whereas in the remaining patients, ...

Ngày tải lên: 09/08/2014, 08:22

... evaluated in our study Patients and Methods Chinese patients with rectal cancer who were treated with curative intent in the Department of Colorectal Surgery, Fudan University Shanghai Cancer Center ... stoma than female patients (33.1% in male vs 15.6% in female, p = 0.008), and stoma patients had lower primary disease than nonstoma patients (mean distance from anal verge: 4.1 cm in stoma patients ... Surgery+CRT (n = 40) CRT+Surgery+CT (n = 40) P Value Mean Globe health status Median (range) Mean Median (range) Mean Median (range) Mean Median (range) 67 75 (25-83) 64 75 (25-83) 69 75 (25-92) 62...

Ngày tải lên: 09/08/2014, 09:20

... co-trimoxazole and NAT2 genotype, with findings apparently correlating with the underlying disease process For instance, in the setting of HIV infection many investigators were unable to demonstrate such an ... gene in 166 patients with SLE, 39 patients with PM/DM, and 195 healthy individuals The percentages of fast acetylators were 89.2%, 89.7% and 91.8% among patients with SLE, patients with PM/DM and ... aminotransferase (AST) or alanine aminotransferase (ALT) levels were higher than twice the upper limit of the normal range The patients and control individuals had no history of alcohol abuse and...

Ngày tải lên: 09/08/2014, 10:20

... remaining potential autoantibody specificities, 13 specificities were present with frequencies ranging from 9% (anti-PM-Scl) to 1% (for instance, anti-KS, anti-U2RNP, and anti-U5RNP; Figure 1) Anti-Mi-2 ... 6/31), and Ku, fibrillarin and PM-Scl (each 19%; 6/31) All anti-Ro positive patients with anti-Ku, anti-fibrillarin, and anti-PM-Scl had anti-Ro52 Anti-Ku The most frequently associated autoantibodies ... in Japanese and African American patients [17,46,47] A combination of historical and geographic factors has resulted in relative genetic homogeneity in French Canadian patients, with ensuing potential...

Ngày tải lên: 09/08/2014, 10:20

... certain malignancies in patients with RA compared with patients without the disease Possible mechanisms for an increased risk of lymphoma in RA patients include the fact that RA results in persistent ... biologics in RA patients compared with non-use and did not find an association between these medications and overall malignancy (excluding non-melanoma skin), lung cancer, breast cancer, or colorectal ... consistent with the risk trends reported in the individual studies This pattern included a clear increase in risks of lung cancer and lymphoma, both Hodgkin and non-Hodgkin, and a potential decrease in...

Ngày tải lên: 09/08/2014, 10:23

... followed 238 patients with RA of less than years in duration longitudinally with comprehensive assessments of clinical and radiographic data at baseline and after and 10 years [15] The patients had ... assuming them to be missing at random without removing the individual from the dataset We investigated the change in NTproBNP levels over time and examined associations between measures of inflammation, ... validated as a marker of CVD in patients with RA Harney and colleagues [25] found that BNP levels were significantly higher in 26 patients with RA than in controls and correlated with end diastolic volume...

Ngày tải lên: 09/08/2014, 10:23