... determine whether the facet joints were the source of pain These included injection of local anaesthetic into the joint itself or the nerves that innervate them, resulting in relief from pain if the pain ... from the nociceptors of the facet joint capsules [32] Generally, the participating chiropractors' views of the acute facet syndrome and the description of chronic facet joint pain found in the ... from the facet joints They described the characteristics of an acute, uncomplicated lumbar facet syndrome in much the same way as chronic pain from the facet joints has been described in the literature...
Ngày tải lên: 13/08/2014, 14:20
... from the serum samples of the patients with acute coronary syndrome Furthermore, using combination of bacteriological and PCR-based methods we show herein that patients with acute coronary syndrome ... On the other hand, serum contains many PCR inhibitors (29) which undermines the usage of quantitative PCR in direct testing of serum specimens Therefore, in the current attempt to evaluate the ... predicted size (194 bp) The TaqMan probe was labelled at the 5' end with 6-carboxyfluorescein as the reporter dye and at the 3' end with 6-carboxytetramethylrhodamine as the quencher An additional...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
... together, these data suggest that the RS-rich region of the SARSCoV N protein is possibly phosphorylated by SRPK1 Phosphorylation of multiple serines within the RS motif The RS motif of the SARS-CoV ... examined whether the SARS-CoV N protein plays a role in premRNA splicing due to the presence of the RS motif but, so far, we not have any evidence to support this hypothesis (data not shown) In the present ... are located in the cytoplasm as well as in the nucleolus [34,35] Nevertheless, the SARS-CoV N protein does not localize substantially to the nucleolus [36,50], as also observed in the present study...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus pptx
... binding with the small molecule involves a larger molecular interface in the case of the former helicase Furthermore, the absence of the S259 OH group in the mutated viral enzyme prevents the formation ... relevance The case is different for the R124W mutation, which is outside the trans-membrane segments, with the arginyl residue being very conserved in all the available related sequences Thus, the ... very far from the active site suggests that S259 is located either in an allosteric site of the enzyme or in a critical position for the overall protein flexibility The fact that the S259 ⁄ L helicase...
Ngày tải lên: 28/03/2014, 23:20
Báo cáo sinh học: " The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
... Furthermore, the juxtaposition of the YxxΦ motif and a ExD (diacidic) motif was found to be essential for the transport of 3a to the cell surface, consistent with the role of these motifs in the ... the plasma membrane into the endosomes Interaction between the adaptor protein complex (AP-2) with the YxxΦ motif present in the cytoplasmic domain of the internalizing protein concentrated the ... decrease in the expression of S on the cell surface Thus, this viral-viral interaction confers the functional role for the YxxΦ motif found in other coronaviruses to the SARS-CoV S This hypothesis...
Ngày tải lên: 18/06/2014, 22:20
Báo cáo hóa học: " The incidence of acute encephalitis syndrome in Western industrialised and tropical countries" pdf
... identifying patients with acute encephalitis syndrome (AES), and then classifying the patients according to the results of laboratory diagnostic tests AES is defined as the acute onset of fever and ... allowing the cases themselves to help describe the temporal and spatial occurrence of JE A similarly high incidence has been reported for other epidemic areas of Southeast Asia such as in Northern ... identified [31] The incidence was notably higher in the southern plains than in the mountainous districts of northern Bali, and was attributed to a wider distribution of rice fields in the south Among...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
... Furthermore, the juxtaposition of the YxxΦ motif and a ExD (diacidic) motif was found to be essential for the transport of 3a to the cell surface, consistent with the role of these motifs in the ... the plasma membrane into the endosomes Interaction between the adaptor protein complex (AP-2) with the YxxΦ motif present in the cytoplasmic domain of the internalizing protein concentrated the ... decrease in the expression of S on the cell surface Thus, this viral-viral interaction confers the functional role for the YxxΦ motif found in other coronaviruses to the SARS-CoV S This hypothesis...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: " Acute compartment syndrome of the hand in Henoch-Schonlein Purpura" ppt
... vessels up to the level of cubital fossa In the late afternoon, the whole left hand was swollen intensely, with extension of the purpura from the hand, up the wrist into the forearm The metacarpophalangeal ... fasciotomy of the thenar and hypothenar compartments Decompression and fasciotomy of the thenar and hypothenar compartments signs of fluid extravasations, inflammation or infection at the site of ... was discharged uneventfully on the fifth post-operative day Discussion This is the first case of acute compartment syndrome of the hand in HSP to be reported in the literature Complications such...
Ngày tải lên: 11/08/2014, 10:22
Báo cáo y học: "Pneumococcal sepsis presenting as acute compartment syndrome of the lower limbs: a case report" docx
... regarding the accepted useful diagnostic readings [4] Whitesides et al suggest that the perfusion of the compartment depends on the difference between the diastolic blood pressure and the ICP [5] They ... conception and design of the paper; and have read and approved the final version of the manuscript for publication References The mechanism of acute compartment syndrome in the setting of sepsis ... Akeson WH: Acute compartment syndromes: diagnosis and treatment with the aid of the wick catheter J Bone Joint Surg Am 1978, 60(8):1091-1095 Moghtaderi A, Alavi-Naini R, Azimi H: Compartment syndrome: ...
Ngày tải lên: 11/08/2014, 20:20
Báo cáo y học: " Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease" pot
... WBCs, and the endothelium could each contribute to their aberrant metabolism We review the role of each of these cell types in the generation of oxygen radicals, and the effects that these molecules ... adherence of sickle PMNs to the vascular endothelium [28] When PMNs become activated or adherent to the endothelium, they can produce oxidants such as O2– and H2O2 through the activation of enzymes ... vascular endothelium of the cremaster muscle Although endothelial production of oxidants is difficult to measure directly in human disease, these in vitro and in vivo data suggest that the endothelium...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo khoa học: " Bench-to-bedside review: β2-Agonists and the acute respiratory distress syndrome" ppsx
... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... mortality on the intensive care unit [102] Central to the development of these infections is colonization followed by invasion of the epithelial cell layer Several studies have investigated the effect ... completion in the UK, and the ARDS Network in the USA is considering a large multicentre trial using nebulized salbutamol The results of these trials will hopefully improve our understanding of the application...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo khoa học: " Using simulation for training and to change protocol during the outbreak of severe acute respiratory syndrome" ppsx
... long it took the first person to don the PPS The other four trainees observed After the simulation we debriefed the entire group and discussed and reinforced pertinent points Then the four remaining ... can be trained in the protocol before the crisis occurs Once the crisis occurs, some HCWs should be immediately transferred from their usual duties to manage the patients The other previously trained ... to don the PPS The first protocol required a PPS for everyone entering the patient's room as part of the arrest team This was based on the assumption that it would take 1/2 minutes to don the PPS...
Ngày tải lên: 12/08/2014, 23:20
Structural study revealing the unique enzymatic mechanism of the severe acute respiratory syndrome (SARS) coronavirus main protease highly mediated by the extra domain
... different pH 18 Chapter - Severe Acute Respiratory Syndrome 1.1 Severe Acute Respiratory Syndrome (SARS) Severe Acute Respiratory Syndrome (SARS) was the first pandemic in the 21st century, initially ... ultracentrifuge 70 Chapter - Dissection Study on the Severe Acute Respiratory Syndrome Main Protease Reveals the Critical Role of the Extra Domain in the Dimerization of the Enzyme 4.1 Results 71 4.1.1 Cloning ... the other coronaviruses, this new coronavirus was named the SARS coronavirus (SARS-CoV) Despite extensive research on the SARS-CoV in the last five years, neither a vaccine nor an effective therapy...
Ngày tải lên: 11/09/2015, 16:06
The acute respiratory distress syndrome (ARDS)
... Pulmonary hypertension The immunology of ARDS Endothelial injury results in increased capillary permeability and the influx of protein-rich fluid into the alveolar space Injury to the alveolar lining ... collapse The immunology of ARDS the development of ARDS also involves… Tumor necrosis factor (TNF) and other cytokines Leukotrienes macrophage inhibitory factor, platelet factors, and others ... 2007 The theoretical answer: Promote alveolar recruitment The Problem: a uniformly applied positive insufflating pressure/breath only opens some alveoli during a timed respiratory cycle The...
Ngày tải lên: 28/10/2016, 20:23
Accelerated strategies in the assessment of emergency patients with possible acute coronary syndromes
... around these six publications and seeks to link the research outcomes achieved in these publications with the overall aims and objectives of the research that forms the basis of this thesis Chapter ... for assessment The candidate was the lead researcher for this element of the research program She conceived the project with the support of the broader research team, undertook the literature ... the inclusion of the papers in this manuscript Additionally the publishers of the relevant Journals have all provided approval for the incorporation of the articles used in this thesis Table of...
Ngày tải lên: 07/08/2017, 11:24
Báo cáo y học: "Management of Critically Ill Patients with Severe Acute Respiratory Syndrome (SARS)"
... Patients with Severe Acute Respiratory Syndrome Am J Roentgenol, 2004 182:493-498 64 Lew T.W., et al Acute respiratory syndrome in critically-ill patients with severe acute respiratory syndrome JAMA, ... ribavirin in another subgroup of 44 patients, there were significant reductions in the need for rescue pulsed corticosteroid therapy, intubation rate and overall mortality In addition to the prevalence ... in single organ failure of the lungs Other complications reported are more likely the result of sepsis and its attending problems, including acute renal failure (6%), acute liver failure (1%),...
Ngày tải lên: 03/11/2012, 10:20
Tài liệu THE ACUTE ABDOMEN pdf
... *Lead poisoning *Campylobacter infections Common Septic Conditions: Acute Appendicitis Acute cholycistitis Acute diverticulitis All Can lead to PERITONITIS PERITONITIS Acute secondary bacterial ... Emergency Laparoscopy Is the patient underlying condition a of surgical or medical nature? Medical causes of acute abdominal pain: *Myocardial infarction *Lobar pneumonia *Acute hepatitis *Sickle ... Mechanical Obstruction a) Simple b) Strangulated Clinical presentation could be: a) Acute b) Chronic c) Subacute d) Acute on chronic INTESTINAL OBSTRUCTION Paralytic Ileus It could be secondary to...
Ngày tải lên: 12/12/2013, 16:15
Tài liệu Acute Coronary Syndromes Edited by Mariano E. Brizzio docx
... in others Over the past decade the treatment of these syndromes has changed dramatically The introduction of novel therapies has impacted the outcomes and surviving rates in such a way that the ... in the pathogenesis of atherosclerosis disease In addition to being part of the coagulation system, they contribute to all phases of the atherosclerosis process (1) The “intervention” in the ... hospitalization 27 The pathophysiological substrate of the unstable angina is now considered Physiopathology of the Acute Coronary Syndromes 41 to be common with the acute myocardial infarction We, therefore,...
Ngày tải lên: 20/02/2014, 08:20
Acute Coronary Syndromes Edited by Mariano E. Brizzio docx
... in others Over the past decade the treatment of these syndromes has changed dramatically The introduction of novel therapies has impacted the outcomes and surviving rates in such a way that the ... in the pathogenesis of atherosclerosis disease In addition to being part of the coagulation system, they contribute to all phases of the atherosclerosis process (1) The “intervention” in the ... hospitalization 27 The pathophysiological substrate of the unstable angina is now considered Physiopathology of the Acute Coronary Syndromes 41 to be common with the acute myocardial infarction We, therefore,...
Ngày tải lên: 31/03/2014, 19:20
báo cáo hóa học: " Satisfaction of inpatients with acute coronary syndrome in Bulgaria" docx
... of them to acute myocardial infarction (AMI) Because of the importance of the IHD, we chose all patients with acute coronary syndrome (ACS) as our study population All patients residing in the ... Bulgaria is associated with the type of hospital, the number of family members living together and the severity of the disease at admission According to these findings, the efforts by hospital managers ... percentages together with the distribution of overall satisfaction 24% of the patients were satisfied with the treatment in the hospital setting, 14% were unsatisfied and 62% of the patients were...
Ngày tải lên: 18/06/2014, 19:20