america bell demonstrated his invention to the public countless exhibitions and by 1877 the first telephone was in commercial use
Anh 8 - Unit 6
Ngày tải lên :
29/05/2015, 18:00
... led to the Scouts Association crossing the Atlantic in 1910? An American businessman, William Boyce got lost in London A boy helped him and explained that he was a scout This meeting led to the ... introduced to scouting c/ : the founding of the Girl 1994 Guides Association and Camp Fire Answer the questions Question 1: When did scouting begin in England? Scouting began in England in 1907 Question ... years later an American businessman, William Boyce, got lost in London A boy helped him and explained that he was a scout This meeting led to the Scout Association crossing the Atlantic in 1910 Although...
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Báo cáo y học: " Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury" ppt
Ngày tải lên :
12/08/2014, 13:22
... and the volume compressed in the ventilator circuit by the difference between the plateau pressure and the positive endexpiratory pressure or [(TV - Volume left in circuit)/ (Ppl - PEEP)] Clinical ... other causes of immunosuppression, fluid intake/output and balance, vital signs, and chest radiographic findings The clinical disorder associated with ALI was considered primary if the cause was ... RK, DM and MM generated the original idea for this research study and collected the data ES collated, analyzed and interpreted the data ES created the figures and wrote the manuscript HJ and ME...
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Báo cáo khoa học: "The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells" doc
Ngày tải lên :
09/08/2014, 03:21
... contributed to the writing of the manuscript All the authors read and approved the final manuscript 17 Acknowledgements This study was sponsored by Zhejiang Provincial Top Key Discipline in Surgery and ... arsenic trioxide was obtained by dissolving arsenic trioxide in 1.65 M NaOH and by diluting in PBS, followed by adjustment of the pH to 7.0 RPMI Medium1640 and FBS were purchased from Invitrogen Ant-Bcl-2 ... proliferation and induce apoptosis in SGC7901 human gastric cancer cells There are two Bcl-2 phenotypes coexisting in SGC7901 cells and the Bcl-2 cytoprotective phenotype can change into a cytodestructive...
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Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
Ngày tải lên :
22/02/2014, 07:20
... reactivated by denaturation and refolding, either by SDS and refolding by dilution into a buffer with 1% BSA, or by guanidinium chloride and refolding by dialysis against NaCl/Pi In this study, PAI-1 was ... either by steric hindrance, by inducing conversion to the latent state, by inducing substrate behaviour, and/ or by inducing conversion to inert polymers [48–52] The present results prompt further ... of the amino acids in positions 53 and 56 in a helix B, 186 in b strand 3A, and position 334 in b strand 5A (Fig 1; the numbering of amino acids in PAI-1 is according to the a1-antitrypsin template...
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Báo cáo Y học: The a1b1 contact of human hemoglobin plays a key role in stabilizing the bound dioxygen Further evidence from the iron valency hybrids potx
Ngày tải lên :
31/03/2014, 15:20
... indicated by the ®rst arrow The unassociated a3+ chains could be removed by the addition of M NaCl as indicated by the second arrow The protein and the heme protein levels were monitored by the absorbances ... step was to construct the iron valency hybrid tetramers containing either the a or b chains in the ferric state, and to examine for their stability properties as compared with the native HbO2 and ... heme), the monomeric form (87%) was predominant in the a chain, while the tetrameric form (99%) was for the b chain This estimation was made on the basis of the results by McDonald et al [16] In...
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Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx
Ngày tải lên :
09/08/2014, 03:24
... expression can be induced by cytokines in human endothelial cells [13,14] The lung is the organ most frequently involved in WG, and in some cases it is the only organ affected [15] Given the potential ... myelomonocytic cell line [5] The following primers were used in this study: PR-3 ‘sense’, 5′-ATCGTGGGCGGGCACGAGGCG (at the beginning of exon 2, corresponding to bases +82 to +101 of the cDNA); and PR-3 ‘antisense’, ... directly involved in the pathogenesis of WG or are merely an epiphenomenon [10] One of the unresolved issues is the inability to explain the nonrandom, selected organ injury that defines the WG...
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Báo cáo y học: "Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute" potx
Ngày tải lên :
09/08/2014, 08:23
... significant reversal in T-cell proliferation when using PGE2 synthesis inhibitors or tryptophane [38] Jorgenson investigated a murine MSC line and found PGE2, but not IDO, to be involved in the immunosuppressive ... affected by MSCs On the other hand, the same group from the Karolinska Institute showed that MSCs reduce the formation of CTLs via a soluble factor, but they are not themselves subject to immune ... downregulated, and DCs exhibit impaired cytokine production and a reduced ability to stimulate T cells MSCs also inhibit the IL-1 and CD40 ligand induced maturation of immature into mature DCs Aggarwal and...
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Báo cáo y học: "Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis" ppsx
Ngày tải lên :
09/08/2014, 14:22
... be the first anti-inflammatory immunocytokine to be tested in the clinical setting and it will be interesting to learn whether the improved performance and selectivity documented in the mouse ... 5'GAGCCGGAAGAGCTACTACCCGATGAGGAAGATTTGATTTCCACCTTG-GTCCCTTG-3' Using this strategy, a HindIII restriction site was inserted at the N-terminus and a complementary part of the linker sequence was inserted at the C-terminus The single-chain Fv and IL10 ... using flexible aminoacid linkers (Figure 2a) The resulting plasmid pKS1 was linearized and used to stably transfect CHO-S cells A short five amino acid linker was used to bridge VH and VL domains...
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Báo cáo y học: "Variations in branching of the posterior cord of brachial plexus in a Kenyan population" ppsx
Ngày tải lên :
10/08/2014, 10:20
... cord into two which then joined to form the radial nerve This is concordant with a report by Kumar [6] in one case from 47 cadavers This rare variation may be caused by the segmental origin of the ... manuscript ML was involved in conception and design of the study, data collection and analysis, drafting of the manuscript OJ was involved in revision and final approval of the manuscript version to be ... manuscript SR was involved in data analysis, drafting, revision and correction of the manuscript SS was involved in conception and design of the study, data collection and analysis, drafting of the manuscript...
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Báo cáo y học: "Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature" ppsx
Ngày tải lên :
11/08/2014, 00:23
... thus channeling the available tryptophan to form kynurenine (Kyn), 3-hydroxykynurenine (3HK), and quinolinic acid (QUIN), rather than the serotonin (5-HT) This leads to a decrease in the availability ... venlafaxine (a mixed serotonin and norepinephrine-reuptake inhibitor, exhibiting serotonin-reuptake inhibition at lower doses, and norepinephrine-reuptake inhibition at higher doses) at the serotonergic ... year taking escitalopram, it was decided gradually Page of to taper and stop his antidepressants On stopping the antidepressants, his joint pain and stiffness started to worsen, and in two weeks,...
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Báo cáo y học: "The role of Qa-2, the functional homolog of HLA-G, in a Behcet''''s disease-like mouse model induced by the herpes virus simplex" pptx
Ngày tải lên :
11/08/2014, 03:20
... and swelling of the face The score of each symptom was one, and the total score before and after treatment was used to determine the severity of BD Mice exhibiting significantly reduced symptoms ... 6A), after which the inserted sequence was confirmed by sequencing using T7 promoter (Figure 6B) The vector was intraperitoneally injected once into mice, and peritoneal macrophages and splenocytes ... could influence IFNγ expression, Qa2 vector was constructed in PC3.1 vector and then administered to normal and BD mice Cloning of the Qa- To confirm the relationship between HLA-G and the NK...
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Báo cáo y học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" ppsx
Ngày tải lên :
11/08/2014, 05:21
... appointments Increasing the productivity of operating theatres by 30% Decreasing the total duration of diagnostics and treatment by 40 to 90%, reducing length of in- hospital stay by 30% Decreasing ... designing the study, acquiring, analyzing and interpreting the data, and drafting the manuscript PS assisted with the analyses and interpretation of the data As research manager of the independent ... data to a central database In this study, these monitoring data were used to model the actual success of the teams An agreement was made with the organisation funding the programme (as well as the...
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Báo cáo y học: " Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature" ppt
Ngày tải lên :
11/08/2014, 12:20
... calcification and some periappendiceal stranding Both mucinous cystadenomas and cystadenocarcinomas have the potential to cause peritoneal seeding leading to pseudomyxoma peritonei However, survival in ... significant cytological atypia or invasion of the appendiceal wall by atypical glands was noted (Figures and 3) A final histopathological diagnosis of mucinous cystadenoma was made The patient remained ... Figure The same field under a higher magnification of 20 × 10 (hematoxylin and eosin stain) There are no significant epithelial atypia and no invasion into the deeper tissue contrast enhancing nodules...
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Báo cáo y học: " Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial" ppsx
Ngày tải lên :
12/08/2014, 23:21
... branch correction in HYPHY [14] In the latter case, we took recombination into account by first detecting recombination breakpoints with GARD [15], and then estimating the dN/dS ratios independently ... greater in this group than in other volunteers Differences in immune response to HIV-1 infection have been pointed out by the rgp120 HIV Vaccine Study Group [3] as one of the potential factors to ... read and approved the final manuscript Acknowledgements This study was supported by a Bill & Melinda Gates Foundation grant to Global Solutions for Infectious Diseases It was also supported by the...
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Báo cáo y học: " Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome" pps
Ngày tải lên :
13/08/2014, 09:20
... highlighting the insertion of the antisense asNef fragment (original Nef coordinates +8544 to +8844) The primers tTA1 and CN1 used to amplify the inverted repeat region are indicated The inverted ... machinery [11] Nef represents a pathogenicity factor that disorders adaptive immunity by down regulating CD4 and MHC-1 receptors, by inhibiting T-cell chemotaxis, and by inducing apoptosis in bystander ... large truncations in the lhNef hairpin structure and therefore deletions in the Nef gene Interestingly, all AS variants inherit a part of the hairpin structure in their genome, there were no perfect...
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Báo cáo y học: "Electrical muscle stimulation preserves the muscle mass of critically ill patients: a randomized study" ppsx
Ngày tải lên :
13/08/2014, 19:20
... good intra- and inter-observer reproducibility [30] The measurements were performed by two operators who were blinded to the randomization, while the repetition of the measurement was made by the ... operator All patients were in the supine position with legs lying flat in extension The position of the probe was selected at the midway between the anterior superior iliac spine and the midpoint ... midpoint of the patella and was placed ventral to the transverse plane and perpendicular to bone surface To prevent impression of the skin, an excess of gel was employed To standardize the measurements,...
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Báo cáo y học: " The electronic version of this article is the complete one and can be found onlin" pot
Ngày tải lên :
14/08/2014, 08:20
... think this is a big improvement, they’re barking up the wrong tree Mink: Uh, yes, as it were Clifford: But I don’t understand what this has to with this month’s column Mink: By this point, neither ... Exactly And what new tools or methods are needed to solve them So here’s a simple idea: At every big meeting of the American Chemical Society and the American Physical Society and so forth, there ... of the major outstanding problems in that area and what sort of things would help get them solved That way, people from other disciplines who might have new ideas or who would be interested in...
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Báo cáo y học: "Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial" pot
Ngày tải lên :
14/08/2014, 08:21
... are known to reduce the production of the main inflammatory cytokines (TNFa, IL-1b, IL-8, and IL-6), and the subsequent recruitment of inflammatory cells into the alveolar space leading to a more ... are known to reduce the production of the main inflammatory cytokines (TNFa, IL-1b, IL-8, and IL-6), and the subsequent recruitment of inflammatory cells into the alveolar space leading to a more ... Glucocorticoids inhibit cytokines and other inflammatory molecules stimulated by bacterial infections that could be harmful to the host However, the use of steroids also exerts a decisive influence in the...
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Báo cáo y học: "The electronic version of this article is the complete one and can be found online" potx
Ngày tải lên :
14/08/2014, 08:21
... GPC3 inhibits their signaling during development by competing with Patched, the Hh receptor, for Hh binding (Figure 2) [19] The binding of Hh to GPC3 triggers its endocytosis and degradation On the ... with the consequent increment on signaling In the Hedgehog (Hh) signaling pathway (right), GPC3 exerts an inhibitory effect The binding of Hh to the receptor Patched (Ptc) triggers the signaling ... chains, which are located close to the carboxyl terminus This places the HS chains close to the cell surface, suggesting that these chains could mediate the interaction of glypicans with other...
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