alzheimer s disease related quality of life instrument

... self-perceived asthma is the disease- specific Asthma Quality of Life Questionnaire (AQLQ)[10] Disease- specific instruments are known to be more sensitive to assess changes within patients [11,12] On the ... missing data for each item of the two questionnaires We then assessed the distributions of the AQLQ and SF-36 domain scores graphically and by looking at skewness and kurtosis Since AQLQ and SF-36 ... instruments showed important ceiling effects, which seemed less marked for the SF-36 To our knowledge, this is the first study to assess the measurement properties of the AQLQ and SF-36 in asthma...

Ngày tải lên: 18/06/2014, 22:20

... RTQ, which is this study 's specifically-developed instrument, the following instruments were used: SF36 is a generic QOL scale consisting of 36 items describing eight dimensions: Physical Function ... between scale scores for the two assessments (≥ 0.70 considered satisfactory) [36] Sensitivity to change was assessed for patients with a degradation or improvement of their health status and/or ... correlations were found between RTQ scores and SF36 scores The dimension scores of RTQ had medium to high correlation (> 0.6) with those of SF36 assessing similar dimensions: PH-RTQ with PF-SF36, RFP-SF36,...

Ngày tải lên: 18/06/2014, 19:20

... (KDQOL-SF) [39] The questionnaire consists of the generic SF-36 [40] as well as 11 multi-item scales focused on quality of life issues specific to patients with kidney disease (Figure 1) Subscales of ... Disease Quality of Life Health -related quality of life was measured with the Kidney Disease Quality of Life Instrument -Short Form (KDQOL-SF) The KDQOL was developed as a selfreport, health -related ... instruments are often used to compare levels of responses across different groups, such analyses of mean differences assume that the scores being contrasted are in fact comparable across groups In this...

Ngày tải lên: 20/06/2014, 15:20

... advantages but these may be less accessible to those with only standard statistical software The hybrid logistic regression/IRT method has been employed successfully in several studies although ... logistic regression a measure such as McKelvey and Zavoina s pseudo-R may be used [1] Non-uniform DIF may be assessed similarly [68] Two sets of rules have been developed to classify DIF using ... cross-cultural response differences We identified only a few studies that attempted to relate DIF results to blinded substantive assessments of the reasons for DIF: most conducted in fields such as educational...

Ngày tải lên: 12/08/2014, 01:21

... PD-specific quality of life instruments in predicting change in criterion indices of disease severity and quality of life (measured with a visual analogue scale); disease- specific measures outperformed ... by disease rating scales [12] Furthermore, generic HRQoL instruments allow comparison of healthrelated quality of life across different disease states While questionnaires for evaluation of HRQoL ... Jahanshahi M: Quality of life in Parkinson s disease: the relative importance of the symptoms Mov Disord 2008, 23:1428-1434 39 Schrag A: Quality of life and depression in Parkinson s disease J...

Ngày tải lên: 20/06/2014, 16:20

... scores was assessed using responsiveness indices including Cohen s effect size (ES)84, the standardized response mean (SRM)85 and Guyatt s responsiveness index (GRI).82, 86 The responsiveness ... health survey SGD - Singapore dollars SLR - simple linear regression SRM - standardized response mean UPDRS - unified Parkinson s disease rating scale USD - US dollars VAS - visual analogue scale ... Parkinsonian disability and severity were assessed using the H&Y stage scale60 and the motor score of the UPDRS by neurologists on the day of the survey.61 The H&Y stage scale assesses patients with...

Ngày tải lên: 11/09/2015, 10:05

... irrespective of the severity of heart disease [23] This recent result affirms previous findings of studies focusing on various dimensions of quality of life [21,24-27] As congenital heart diseases ... countries [28,29] we considered it necessary to assess the health -related quality of life of Hungarian children with heart disease Page of 12 Among several instruments we decided to use the Pediatric ... although mode of administration (in person versus mail survey) has been widely studied A related issue is the incompleteness of answers from those who respond This limitation manifested strongly on...

Ngày tải lên: 18/06/2014, 19:20

... 3) Satisfied; 4) So-so; 5) Dissatisfied; 6) Fairly dissatisfied; 7) Very dissatisfied [37] Statistical analysis In computing scale scores, missing substitution by the means of non missing items ... Functional status Self-reported functional status was assessed by the Exertional Capacity Scale (ECS) consisting of nine items measuring physical function, a subscale of the disease specific SAQ Social ... was 0.77 Anxiety and depression were assessed by self-report using the Hospital Anxiety and Depression Scale (HADS), which consists of seven items for anxiety (HADS-A) and seven for depression...

Ngày tải lên: 18/06/2014, 22:20

... Presence No 280 (57.9%) Yes 204 (42.1%) - statistical mean Statistics Statistical analyses were performed with an SPSS program (version 14.0) Analyses for CRP SNPs and haplotypes used the most ... drugs; SNPs: single nucleotide polymorphisms; SP: senile plaques; TASTY: Tampere autopsy study; TMAs: tissue microarrays Acknowledgements Many thanks to Heini Huhtala and Ilkka Seppälä (for assistance ... development of lesions, which then leads to other processes and damage to neurons, thus setting off a chain of events leading to AD The absence of statistically significant associations between...

Ngày tải lên: 19/06/2014, 22:20

... Parkinson 's disease the relationship between disease severity and HRQL is linear, whereas in other diseases, such as chronic coronary heart disease, a non-linear relationship was observed One of ... various determinants of disease severity and HRQL [28] According to its results, lung function and HRQL express several different aspects of disease severity in COPD As was found in a study of asthma ... HRQL instruments (utility instruments) are increasingly used in clinical studies Although their use is established in many fields, such as oncology and gastrointestinal disease, questionnaires are...

Ngày tải lên: 20/06/2014, 15:20

... care setting, with the aim of estimating the use of health resources and assessing the HRQoL of patients with stable COPD As the condition progresses, patients with COPD experience a progressive ... expressed as frequencies (percentages) * Value expressed as mean ± standard deviation (minimum; maximum) Assessment of the patients A single visit was completed, collecting in all cases the sociodemographic ... patients with severe COPD The use of oxygen therapy was associated with a significant reduction of the quality of life, in both PCS-12 and MCS-12 Table shows the distribution of the mean scores of...

Ngày tải lên: 20/06/2014, 15:20

... with sickle cell disease: mediation of pain by internalizing symptoms and parenting stress Health Qual Life Outcomes 2008, 6:60 28 Eiser C, Morse R: Quality- of- life measures in chronic diseases of ... of the questionnaire required 20 minutes Statistical analysis The Statistical Package for the Social Sciences (SPSS version 16.0) was used to manage and analyze the data First, missing values ... HRQoL on several domains [13], this study did not yet consider the impact of low socio-economic status (SES) on HRQoL Subsequent studies that did specifically address the role of low SES yielded...

Ngày tải lên: 20/06/2014, 15:20

... van Rossum et al [4], the greater usefulness of general measures such as the SF-36 survey was assumed This commonly used instrument allows comparisons across conditions and interventions Moreover, ... artery disease [4-7] The causes of this state are frequently the lack of the possibility of revascularization, atherosclerosis progression, instability of the subsequent atherosclerotic plaques, ... inclusion in the study All procedures were conducted in compliance with the Declaration of Helsinki Page of Statistics Statistical analysis was conducted using a licensed version of statistical software...

Ngày tải lên: 20/06/2014, 15:20

... HADS-A, HADS-D, and BFI scores for the disease- free survivors of DTC and the control group are shown in Table Disease- free survivors of DTC had greater levels of distress according to the HADS-A ... includes cancer patients [20] It consists of 14 questions related to the two domains of depression and anxiety, with seven questions focus on depression (HADS-D) and the other seven focus on anxiety ... Further study is required to investigate the relationship between TSH suppression, depression, and anxiety Conclusion Our study shows that disease- free survivors of DTC patients experience significantly...

Ngày tải lên: 20/06/2014, 16:20

... lesser scores representing better AS-specific quality of life Recent research has suggested that the ASQOL is a psychometrically sound and responsive measure of disease- specific quality of life ... The ASAS20 response includes assessment of BASFI scores [40], and was the primary endpoint of ATLAS SF-36 SF-36 is a generic health status instrument and consists of eight domains: Physical Function, ... peripheral joints, and entheses [1] Symptoms of AS include pain, joint stiffness, and the loss of spinal mobility These clinical symptoms and the subsequent disease progression result in substantial...

Ngày tải lên: 09/08/2014, 14:22

... van Rossum et al [4], the greater usefulness of general measures such as the SF-36 survey was assumed This commonly used instrument allows comparisons across conditions and interventions Moreover, ... artery disease [4-7] The causes of this state are frequently the lack of the possibility of revascularization, atherosclerosis progression, instability of the subsequent atherosclerotic plaques, ... inclusion in the study All procedures were conducted in compliance with the Declaration of Helsinki Page of Statistics Statistical analysis was conducted using a licensed version of statistical software...

Ngày tải lên: 12/08/2014, 00:20

... HADS-A, HADS-D, and BFI scores for the disease- free survivors of DTC and the control group are shown in Table Disease- free survivors of DTC had greater levels of distress according to the HADS-A ... includes cancer patients [20] It consists of 14 questions related to the two domains of depression and anxiety, with seven questions focus on depression (HADS-D) and the other seven focus on anxiety ... Further study is required to investigate the relationship between TSH suppression, depression, and anxiety Conclusion Our study shows that disease- free survivors of DTC patients experience significantly...

Ngày tải lên: 12/08/2014, 01:21

... worse with stage of disease Mean Page of SGRQ symptom and impact scores declined across stages to 3, but stage scores were slightly less severe than stage Mean PCS and MCS scores both demonstrated ... across the stages (p = 0.25) Mean EQ-5D VAS scores were different across stage of disease, with lower mean scores for more severe stage of disease (p = 0.02) Using the SGRQ total score as the ... ratio; SGRQ: St George s Respiratory Questionnaire; ref: reference; ANOVA: analysis of variance; KWT: Kruskal-Wallis test Discussion The results of this study supported the hypothesis that the disease- specific...

Ngày tải lên: 12/08/2014, 01:22

... version of Kidscreen-52 questionnaire to assess the HRQoL of children and Page of 10 Table Demographic characteristics of study sample Oncology sessions (n = 32) Diabetes sessions (n = 55) JIA session ... by a time related positive change in HRQoL A generic measure of HRQoL was chosen which allows for assessment of adolescents with different diseases Methods Design of the study We designed repeated ... chi-square test assessed pretest differences between disease groups on age, on gender, on previous camp experience and on KIDSCREEN scales’ scores Table summarizes the means (standard deviations...

Ngày tải lên: 12/08/2014, 01:22

... [parents’ assessment], p = 0.032 [patients’ assessment]), global QoL (p = 0.012 [parents’ assessment]) and interests and hobbies (p = 0.023 [patients’ assessment]) With the exception of ‘interests ... Health -related quality of life and functionality measures Functionality and HRQoL outcomes were assessed at baseline and study end using the disease non-specific, ‘Inventory for Assessment of Quality of Life ... patients who had at least one dose of OROS® MPH and had safety data reported Other assessments Results Problems concerning social interactions and tasks were assessed via several non-validated questions...

Ngày tải lên: 13/08/2014, 18:22