allogeneic stem cell transplantation for acute lymphoblastic leukaemia in adults
Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx
Ngày tải lên :
10/08/2014, 21:23
... days to +28) for GVHD prophylaxis; Caspofungin for prophylaxis of fungal infections] Tropisetron was used during the chemotherapy and conditioning (E) period of acute GVHD [alanine aminotransferase ... the conditioning and within 100 days after transplantation, although indirect hyperbilirubinemia repeatedly happened during chemotherapy with daunorubicin, idarubicin, and cytarabine prior to ... http://www.jhoonline.org/content/4/1/9 Page of Figure Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation Chronological dates of the treatment courses were indicated...
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báo cáo khoa học: "Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia" potx
Ngày tải lên :
10/08/2014, 22:21
... http://www.jhoonline.org/content/3/1/36 an approach of pharmacokinetic-targeted IV Bu/Flu from 2004 onward as a uniform conditioning strategy in the setting of allogeneic transplantation for acute myelogenous ... Andersson BS: Once-daily intravenous busulfan given with fludarabine as conditioning for allogeneic stem cell transplantation: study of pharmacokinetics and early clinical outcomes Biol Blood ... conditioning regimen for allogeneic stem cell transplantation in patients with high-risk acute myeloid leukemia in first complete remission Bone Marrow Transplant 2008, 41:721-727 Schmid C, Schleuning...
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Báo cáo y học: "Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms" pps
Ngày tải lên :
10/08/2014, 21:23
... http://www.jhoonline.org/content/4/1/39 suggesting maturation into the basophil vs mast cell lineages Further immunocytochemical stainings were performed showing CD203c expression in the absence ... of stem cell infusion Discussions and Conclusions Here we report a case of a secondary AML developing from donor-derived cells in a breast cancer patient who underwent allogeneic stem cell transplantation ... of the AML blast cell sample obtained after transplantation, and of the donor bone marrow cells The 11 tested microsatellite markers are often used in forensic medicine for individual identification...
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Tài liệu Review of Chronic Graft- Versus-Host Disease in Children After Allogeneic Stem Cell Transplantation: Nursing Perspective pptx
Ngày tải lên :
12/02/2014, 19:20
... mends a system for scoring chronic GVHD manifestations in organs and sites, including the skin, mouth, eyes, gastro intestinal tract, liver, lungs, joints and fascia, genital tract, and performance, ... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre activity and production of autoantibodies, causing targetorgan damage, including skin, mucosa, eyes, joints,...
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Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx
Ngày tải lên :
09/08/2014, 01:23
... marrow stem cell transplantation for severe systemic lupus erythematosus of long duration Lupus 1997, 6:545-548 Burt RK, Traynor A, Ramsey-Goldman R: Hematopoietic stemcell transplantation for systemic ... versus the Hopkins’ treatment protocol incorporating high-dose cyclophosphamide without stem cell support Competing interests None declared References 10 11 12 13 14 Marmont AM, van Lint MT, Gualandi ... Therefore, circulating T cells in a healthy person normally possess a T -cell receptor repertoire selected to a self-epitope Immune cells may be viewed as a dynamic equilibrium that maintains steady...
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Báo cáo y học: "Stem cell transplantation for rheumatic autoimmune diseases" potx
Ngày tải lên :
09/08/2014, 10:23
... antigen-presenting cells, presenting so-called host minor histocompability antigens DCs, specialised in presenting antigens to donor effector cells, are mainly involved in this setting and probably also in ... obtained from studies showing increases in T -cell receptor excision circles and CD31+ T cells and normalisation of new T -cell receptor repertoires [53,54] Allogeneic hematopoietic stem cell transplantation ... administration of mesenchymal stem cells or T-regulatory cells [47] In a recent prospective clinical trial, 56 patients with severe acute GVHD were treated with mesenchymal stem cells obtained...
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báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps
Ngày tải lên :
10/08/2014, 22:20
... donor hematopoietic stem cells by combining G-CSF mobilized peripheral blood with bone marrow stem cells, both depleted of T cells, following TBI-based conditioning regimens[16-18] In their early ... haploidentical T -cell- replete hematopoietic stem cell transplantation Hematologica 2007, 92:414-417 Bignon JD, Gagne K: KIR matching in Hematopoietic stem cell transplantation Curr Opin Immunol 2005, ... stem cell transplantation using unrelated donors Blood 2004, 103:2860-2862 Lowe EJ, Turner V, Handgretinger R, et al.: T -cell alloreactivity dominates natural killer cell alloreactivity in minimally...
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Báo cáo y học: " Successful treatment of severe sinusoidal obstruction syndrome despite multiple organ failure with defibrotide after allogeneic stem cell transplantation: a case report" ppsx
Ngày tải lên :
11/08/2014, 17:21
... downregulation of the release of plasminogen activator-inhibitor It also seems to decrease endothelin activity [8] The reason for the gastrointestinal bleeding in our patient is hard to trace but ... hepathomegaly and ascites; (b) liver tissue obtained through transjugular liver biopsy, haematoxylin eosin stained with necrosis and inflammatory round -cell infiltration through transjugular liver biopsy ... As highlighted in our report, defibrotide is the most promising drug in the treatment of the former, almost lethal, severe SOS to date To increase response to treatment, ongoing investigations...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc
Ngày tải lên :
12/08/2014, 04:21
... Bilateral interstitial infiltrates clinical studies have to be performed to examine the frequency of clinically relevant HHV-6 infections in these patient cohorts Consent statement Written informed ... herpesvirus DNA in plasma after allogeneic stem cell transplantation: incidence and clinical significance J Infect Dis 2006, 193:68-79 Volin L, Lautenschlager I, Juvonen E, Nihtinen A, Anttila ... hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx
Ngày tải lên :
12/08/2014, 04:22
... Bilateral interstitial infiltrates clinical studies have to be performed to examine the frequency of clinically relevant HHV-6 infections in these patient cohorts Consent statement Written informed ... herpesvirus DNA in plasma after allogeneic stem cell transplantation: incidence and clinical significance J Infect Dis 2006, 193:68-79 Volin L, Lautenschlager I, Juvonen E, Nihtinen A, Anttila ... hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious...
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Báo cáo y học: "Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation" pot
Ngày tải lên :
10/08/2014, 21:23
... mM MgCl2 After an initial denaturation at 95°C for min, 45 cycles consisting of 95°C for 30 s and 67°C for were performed The amplification was performed on MJ Research DNA Engine Opticon PCR cycler ... and reaching a plateau months after HSCT, indicating ongoing thymic output Although fludarabine-based, non-myeloablative conditioning was performed in both studies, the regimen used in the Bahceci ... BioSciences, USA) Stainings were performed by incubating cells with the appropriate pool of antibodies for 30 at 4°C followed by a series of washes with phosphate-buffered saline solution supplemented...
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Báo cáo y học: "The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI" ppsx
Ngày tải lên :
10/08/2014, 21:23
... declines in IQ as discussed below The finding of similar outcomes in males and females is reassuring Initial reports of inferior outcomes in girls came from relatively small studies using combinations ... confidence intervals ruling out point differences These results remain unchanged after allowing for age at the start of treatment, gender and number of previous tests taken In addition, examining the ... neuropsychological outcome in ALL are poorly understood and in fact in other areas of acute brain injury, such as head injury, girls usually have better outcomes than boys Again, changes in therapy protocols...
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Tài liệu INNOVATIONS IN STEM CELL TRANSPLANTATION doc
Ngày tải lên :
18/02/2014, 04:20
... blood cell or a brain cell During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably ... the recent developments in the field of basic and clinical aspects of stem cells and cell transplantation Although we are close to finding pathways for stem cell therapies in many medical conditions, ... transplanted stem cells in the host In conclusion, Cell Transplantation is bridging cell transplantation research in a multitude of disease models as methods and technology continue to be refined The...
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Tài liệu New Advances in Stem Cell Transplantation Edited by Taner Demirer ppt
Ngày tải lên :
20/02/2014, 08:20
... factors into somatic cells By using these viral delivery systems, 12 New Advances in Stem Cell Transplantation Fig Methods for producing induced pluripotent stem cells (iPSCs) by non-integrating ... factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells Stem Cells 27, 30013011 22 New Advances in Stem Cell Transplantation Rai, K., Huggins, I.J., James, ... medicine or reparative medicine During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased...
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báo cáo hóa học: " Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study" pdf
Ngày tải lên :
18/06/2014, 19:20
... might be addressed in future studies However, since the peak incidence of childhood ALL is in young children, obtaining self reports will be a continuing problem in QoL studies during treatment Although ... During maintenance treatment we found no improvement in QoL at T2 for any (sub)score, as was found by Eiser et al [15] during the first, most intensive, year of treatment The decline in QoL for ... life during post-induction chemotherapy in children with acute lymphoblastic leukemia in remission: An influence of corticosteroid therapy International journal of oncology 1997, 11:333-339 Hinds...
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báo cáo hóa học: " Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study" pdf
Ngày tải lên :
20/06/2014, 15:20
... Health-related quality of life during post-induction chemotherapy in children with acute lymphoblastic leukemia in remission: An influence of corticosteroid therapy Int J Oncol 1997, 11(2):333-339 ... psychosocial) Items are scored using a four to six point Likert scale and converted to a to 100 point continuum, with higher scores indicating better QoL The original reference period of the CHQ ... scored using a four point Likert scale and reflect on the past week Higher scores indicate better QoL Analysis The Statistical Package for Social Sciences for Macintosh version 18.0 was used for all...
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báo cáo hóa học:" Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study" pdf
Ngày tải lên :
20/06/2014, 16:20
... might be addressed in future studies However, since the peak incidence of childhood ALL is in young children, obtaining self reports will be a continuing problem in QoL studies during treatment Although ... During maintenance treatment we found no improvement in QoL at T2 for any (sub)score, as was found by Eiser et al [15] during the first, most intensive, year of treatment The decline in QoL for ... life during post-induction chemotherapy in children with acute lymphoblastic leukemia in remission: An influence of corticosteroid therapy International journal of oncology 1997, 11:333-339 Hinds...
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Báo cáo y học: "A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes." ppsx
Ngày tải lên :
09/08/2014, 20:22
... for providing the recombinant plasmid containing the cDNA of Olig2; Dr Groner for providing the recombinant plasmid containing the cDNA of Runx1; Dr Whitelaw for providing the recombinant plasmid ... genes following single gene over-expression in our cell bank mouse ES cell lines versus transchromosomic Tc1 mouse ES cell lines The colors indicate the overexpression experiment in which the ... produced the first resource for systematic overexpression of single HSA21 genes in mES cells using an inducible system Our cell bank can be used to understand how much, and in what way, the dosage...
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