allogeneic hematopoietic stem cell transplantation ppt

... Keywords: Hematopoietic stem cell transplantation B-thalassemia major Fanconi’s anemia Immunodeficiency diseases Inherited metabolic disorders A B S T R A C T Allogeneic hematopoietic stem cell transplantation ... (2015) 6, 449–458 Cairo University Journal of Advanced Research ORIGINAL ARTICLE Allogeneic hematopoietic stem cell transplantation for non-malignant hematological disorders Hossam K Mahmoud a, ... by Elsevier B.V on behalf of Cairo University Introduction Patients and methods Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative modality for a variety of

Ngày tải lên: 15/01/2020, 06:21

... https://doi.org/10.1186/s12887-020-02028-6 REVIEW Open Access Busulfan systemic exposure and its relationship with efficacy and safety in hematopoietic stem cell transplantation in children: a meta-analysis Xinying ... a key component of several conditioning regimens used before hematopoietic stem cell transplantation (HSCT) However, the optimum systemic exposure (expressed as the area under the concentration-time ... efficacy, and pharmacokinetics of intravenous busulfan in children undergoing allogeneic hematopoietic stem cell transplantation Pediatr Blood Cancer 2010;54(2):291–8 16 Vassal G, Michel G, Espérou

Ngày tải lên: 29/05/2020, 18:56

... Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation Michaela Döring1*, Karin Melanie Cabanillas Stanchi1, Markus Mezger1, ... localized bacterial, viral and fungal infections are known as adverse events after hematopoietic stem cell transplantation representing the major cause for morbidity and mortality Detection and ... events, 61 consecutive pediatric patients with a median age of 7.0 years who underwent hematopoietic stem cell transplantation were enrolled in this single-center retrospective study Interleukin-1

Ngày tải lên: 28/09/2020, 01:35

... of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968– 99 The Lancet 2003;361(9357):553-560 Buckley RH Transplantation of hematopoietic stem cells in human ... February 21, 2017 For personal use only Abstract Hematopoietic stem cell transplantation (HSCT) cures the T-lymphocyte, B-lymphocyte and Natural Killer (NK) cell differentiation defect in IL2RG/JAK3 ... after hematopoietic stem cell transplantation of a single-center cohort of 90 patients with severe combined immunodeficiency Blood 2009;113(17):4114-4124 Pai S-Y, Logan BR, Griffith LM, et al Transplantation

Ngày tải lên: 04/12/2022, 15:13

... Allogeneic stem cell transplantation, HLA-matched related donor, Acute myeloid leukemia, In vivo T cell depletion, Graft-versus-host disease, Relapse incidence, GRFS Background Allogeneic hematopoietic ... aGVHD: Acute graft-versus-host disease; allo-SCT: Allogeneic hematopoietic stem cell transplantation; AML: Acute myeloid leukemia; ANC: Absolute nuclear cells; ATG: Anti-thymocyte globulin; BM: Bone ... sibling allogeneic hematopoietic cell transplantation in AML and MDS Bone Marrow Transplant 2016;51(7):961–6 Shimoni A, Hardan I, Shem-Tov N, Yeshurun M, Yerushalmi R, Avigdor A, et al Allogeneic hematopoietic

Ngày tải lên: 04/12/2022, 14:56

... cytomegalovirus reactivation [49]. Mechanisms of action of hematopoietic stem cell transplantation in autoimmune disease Autologous hematopoietic stem cell transplantation In autologous HSCT, conditioning ... showing increases in T -cell receptor excision circles and CD31 + T cells and normalisation of new T -cell receptor repertoires [53,54]. Allogeneic hematopoietic stem cell transplantation The interaction ... after autologous stem cell transplantation. Acta Haematol 2008, 119:22-27. 55. Peggs KS: Reconstitution of adaptive and innate immunity fol- lowing allogeneic hematopoietic stem cell transplantation

Ngày tải lên: 09/08/2014, 10:23

... co-cultured CD34+ hematopoietic stem cells with 3A6 cells, we noted the formation of cobblestone areas from hematopoietic cells that transmigrated beneath the layer of 3A6 cells (Figure 3C) Previously, ... mesenchymal stem cell in vitro BMC cell biology 2006, 7:14 Hung SC, Chen NJ, Hsieh SL, Li H, Ma HL, Lo WH: Isolation and characterization of size-sieved stem cells from human bone marrow Stem cells ... hMSCs converges toward embryonic stem cells Principal component analysis comparing the gene expression profiles of 3A6, embryonic stem cells (ESC), mesenchymal stem cells (MSC), and various tissues

Ngày tải lên: 10/08/2014, 05:21

... vasculogenesis: Cellular approach Adult mesenchymal stem cells Smooth muscle cells Hematopoietic stem cells and progenitor cells Endothelial progenitor and endothelial cells Bone marrow-derived ... phosphatase RnD systems, USA RnD systems, USA Sigma, USA Sigma, USA Militenyl Biotech, USA Dako, Germany Chemicon, USA Chemicon, USA RnD systems, USA RnD systems, USA RnD systems, USA RnD systems, USA ... embryonic stem cell derived CD133+ endothelial progenitor cells in treating ischemic heart disease. CD133+ endothelial progenitor cells were differentiated from human embryonic stem cells by transduction

Ngày tải lên: 14/09/2015, 09:26

... Van Pham et al Stem Cell Research & Therapy 2013, 4:91 http://stemcellres.com/content/4/4/91 RESEARCH Open Access Activated platelet-rich plasma improves adipose-derived stem cell transplantation ... injured articular cartilage Keywords: Adipose tissue-derived stem cells, Articular cartilage injury, Joint failure, Mesenchymal stem cells, Osteoarthritis, Platelet-rich plasma Introduction Platelet-rich ... any medium, provided the original work is properly cited Van Pham et al Stem Cell Research & Therapy 2013, 4:91 http://stemcellres.com/content/4/4/91 osteoarthritis [5] In a porcine model, PRP

Ngày tải lên: 12/12/2017, 05:46

... after Autologous Hematopoietic Stem Cell Transplantation in Type Diabetes Front Immunol 2017 167 45 Gu Y, Gong C, Peng X, Wei L, Su C, Qin M, et al Autologous hematopoietic stem cell transplantation ... Autologous Stem- Cell Transplantation for Severe Scleroderma N Engl J Med 2018 378 35-47 24 van Laar JM, Farge D, Sont JK, Naraghi K, Marjanovic Z, Larghero J, et al Autologous hematopoietic stem cell transplantation ... haemopoietic stem- cell transplantation for aggressive multiple sclerosis a multicentre single-group phase trial Lancet 2016 doi http: dx.doi org10.1016S0140-67361630169-6 35 Hematopoietic stem cell therapy

Ngày tải lên: 16/01/2020, 02:44

... factor; hBMSCs: Human bone marrow stromal cells; hHSCs: Human hematopoietic stem cells; HPC: Hematopoietic progenitor cells; hPSC: Human pluripotent stem cell; IHC: Immunohistochemical; KC: Keratinocyte-derived ... cultured in Stemline® II Hematopoietic Stem Cell Expansion Medium (SigmaAldrich, catalog no S0192) containing 100 ng/mL stem cell factor, thrombopoietin, and G-CSF (all obtained from R&D Systems, ... 20:619 Page of 15 Fig Mouse model of peripheral blood hematopoietic stem cell mobilization a, b, c The mouse model of hematopoietic stem cell (HSC) mobilization was designed based on a protocol

Ngày tải lên: 06/08/2020, 05:25

... Autologous blood stem cell transplantation, High-dose chemotherapy, Outpatient setting, Outpatient supportive care Background High-dose (HD) chemotherapy and autologous blood stem cell transplantation ... CD34+ cells × 106/kg 3.3 (2.1–6.5) PBSC storage duration, months (0–144) Remission post HD and ABSCT CR (10) nCR (38) VGPR (14) PR (33) MR (0) SD (5) PD (0) ABSCTautologous blood stem cell transplantation, ... 10.1186/s12885-017-3137-4 RESEARCH ARTICLE Open Access High-dose chemotherapy and autologous stem cell transplantation of patients with multiple myeloma in an outpatient setting Katharina Lisenko1,

Ngày tải lên: 20/09/2020, 01:31

... unresponsive immune system with a new, tumor-sensitive immune system by allogeneic hematopoietic stem cell transplantation (alloHSCT) Transplantation of allogeneic hematopoietic stem cells from a human-leukocyte-antigen ... −2: Cyclophosphamide 60 mg/m2/d (=120 mg/kg total dose) Stem cell product and stem cell transplantation Only mobilized hematopoietic stem cells obtained from peripheral blood by hemapheresis according ... T4-status Allogeneic hematopoietic stem cell transplantation in solid tumors As the field of cancer immunology has grown, a deeper understanding of the immune system’s recognition of tumor cells

Ngày tải lên: 05/11/2020, 01:33

... ECM, extracellular matrix; SDF-α, stromal derived factor-1α; ANG-1a, AC CE P angiopoitin-1; CAR cell, CXCL12-abundant reticular cell; SCF, stem cell factor; HSC, hematopoietic stem cell; MSC, ... GSLC, glioma stem- like cell; HA, hyaluronic acid; HHIP, human hedgehoginteracting protein; HIF-1α, hypoxia-induced factor-1α; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cell; IHH, ... [4-6] Since mature blood cells are short-lived, hematopoietic stem cells (HSCs) are required throughout life to replenish progenitor and precursor cells [5, 7] D A stem cell niche is a specialized

Ngày tải lên: 26/07/2023, 07:40

... antidiuretic hormone, 47t, 261-62 T Tacrolimus See FK-506/Tacrolimus T -cell depletion, of donor cells, prior to infusion, 117 T -cell mediated deficiency, diagnostic studies, 285 Tetracycline hydrochloride, ... evaluation of, 265t Pericardiocentesis, 265-66 Peripheral blood smear(s), 225 Peripheral blood stem cells (PBSCs) BMT versus, 118 engraftment of, 122 infusion of, 121-22 mobilization/collection ... 62-65, 64t Stool examination, 215-16, 270-71 Stool osmotic gap formula, 144 Storage of marrow /stem cell( s), 118 Substance abuse, in BMT populations, 420 Suicidal ideation, in BMT populations,

Ngày tải lên: 10/08/2014, 08:20

... marrow stem cells in ischemic brain. Acta Neurochir Suppl 2006, 99:123-124. 11. Li J, Sun CR, Zhang H, Tsang KS, Li JH, Zhang SD, An YH: Co- transplantation of neural stem cells and Schwann Cells ... administration or neural stem cell transplant. A: reddish brown coloration of caspase III immunoreactivity along the ventricular lining of cells of ischemic rat having undergone neural stem cell transplant ... in the lesioned micro-environment of the CNS. Materials and methods Culture of Neural stem cells Neural stem cells were harvested from the cortex of E16 Sprague-Dawley rat embryos. The head was

Ngày tải lên: 18/06/2014, 16:20

... availability of various cellular sources for experimental investigations [6,7,10-15] including bone marrow-derived mesenchymal stem cells (BMDMSCs), hematopoietic stem/ progenitor cells, and cells of embryonic ... organs during ischemia-reperfusion (IR) injury We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs) protect the kidney against oxidative stress and inflammatory stimuli in rat during ... [7] Growing data have shed considerable light on the effectiveness and safety of mesenchymal stem cell (MSC) treatment in improving ischemia-related organ © 2011 Chen et al; licensee BioMed Central

Ngày tải lên: 18/06/2014, 19:20

... disease. Keywords allogeneic hematopoietic stem cell transplantation, chronic graft-versus-host disease, children, incidence, risk factors Introduction Hematopoietic stem cell transplantation (HSCT) ... blood stem cell transplantation; BMT, bone marrow transplantation; UBMT, unrelated bone marrow transplantation; T-UBMT, T -cell- depleted bone marrow transplantation; UCBT, umbilical cord blood transplantation; ... common after peripheral blood stem cell transplantation than BMT because it is generally accepted that peripheral blood stem cells con- tain greater numbers of infused T-cells (Bishop, 2009; Schmitz...

Ngày tải lên: 12/02/2014, 19:20

... in mouse embryonic stem cells. Stem Cells 27, 3001- 3011. New Advances in Stem Cell Transplantation 14 Fig. 3. Methods for production of induced pluripotent stem cells (iPSCs) by excisable ... carcinoma and embryonic stem cells. Mol Biol Cell 16, 5719-5735. NEW ADVANCES IN STEM CELL TRANSPLANTATION Edited by Taner Demirer New Advances in Stem Cell Transplantation 8 3. ... Hematopoietic Stem Cell Transplantation (HSCT) 517 Ami J. Shah, Tena Rosser and Fariba Goodarzian Chapter 26 Adenoviral Infection – Common Complication Following Hematopoietic Stem Cell Transplantation...

Ngày tải lên: 20/02/2014, 08:20