... as the main author RSUY was involved in reviewing the literature and proof reading ofthe manuscript RSUY has approved the final manuscript SSB is the senior author and was responsible for final ... radial head The reduction was achieved in supination and immobilisation ofthe elbow in flexion and supination gave a favourable final outcome Inthepresenceof major distracting injuries like ... in a position of hyperextension and supination [4] Typical clinical presentation is a maintenance of flexion and extension ofthe elbow following the injury but loss of supination and pronation...
... experiments, cells were preincubated for 0.5–1 h inthe methionine ⁄ cysteine- free DMEM and labeled with 50–100 lCi of [35S]methionine ⁄ cysteine for 0.5 h inthe fresh methionine ⁄ cysteine- free MEM After ... out inthepresenceofthe canine microsome, TNSALP (1559delT) became a 80 kDa form; however, the appearance ofthe 80 kDa form was greatly diminished inthepresenceof Bz-Asn-Gly-ThrNH2, an inhibitor ... cross-linking reactions via thecysteineresidues To address this possibility, three cysteines were substituted for serine residuesinthe C-terminal extension of TNSALP (1559delT) (Fig 1) Initially...
... coding for cysteine proteinases inthe latex of V stipulata and V · heilbornii Based on these sequences, the evolution ofthecysteine proteinases within the Caricaceae was investigated Furthermore, ... protein content in their latex; and (2) thepresenceof other cysteine proteinases or isoforms inthe latex To investigate these two hypotheses, the protein concentration per milligram of dried ... aid inthe protection against degradation, or in targeting or maturation ofthe enzyme, as was shown before in cathepsin C, which also belongs to the papain family ofcysteine proteinases [27] The...
... screening the L donovani EMBL-3 genomic library was developed on the grounds of a partial amino acid sequences from the organisms appearing in Fig and Fig Scheme ofthe alignment ofcysteineresidues ... activity inthe absence of AdoMet, its activity was not enhanced inthepresenceof AdoMet The Cys92 residue is thus involved inthe stimulatory effect of PPPi cleavage induced by AdoMet and may be the ... cleave PPPi, the respective cysteine may plausibly be thought to be involved inthe first step ofthe reaction (synthesis of AdoMet and PPPi), with no role in PPPi cleavage The results of these studies...
... glycosylation These findings are intriguing given that these three cysteineresidues are absolutely conserved not only inthe F proteins of other Pneumovirinae, but also inthe F proteins ofthe Paramyxovirinae ... analyze the contribution ofthe individual cysteineresiduesinthe extracellular domain in protein expression and cell fusion ofthe HRSV F protein and represents the first analysis ofthe contribution ... To determine the contribution ofthe individual cysteineresiduesinthe extracellular domain (ECD) to its functions, a panel of mutations in which each cysteine residue inthe ECD ofthe HRSV...
... style They give the main points and state the criticism at the top inthe headline andthe lead paragraph(s) The body ofthe articles then adds details, statements, and comments from people involved ... together at the beginning ofthe sentence, but in other case, they are separated or the writer delays the appearance ofthe verb Thus, one ofthe reason people sometimes misunderstand the information ... works This type of criticism is based on the rules and principles that regulate the practice ofthe critic, the art of judging with knowledge and propriety ofthe beauties and faults of a literature...
... debt financing On the other hand, the individual with low income and savings is more attracted towards debt financing The selection of income group andthe means of income are very important The ... evaluate the level of knowledge and interest about micro financing prevailing inthe lower income groups The awareness of micro financing may encourage the poor people to empower themselves and contribute ... ignoring the idea of business sharing within their respective communities, thus discouraging the notion of group lending, which is termed as the baseline of micro finance model However, the MFIs...
... (C), inthepresenceof 100 lM MPP+ (D), inthepresenceof 200 lM MPP+ (E), inthepresenceof 100 lM MPTP and 50 lM dopamine (F), inthepresenceof 200 lM MPTP and 50 lM dopamine (G), inthepresence ... solid line), inthepresenceof 100 lM neurotoxin ( , dotted line), inthepresenceof 200 lM neurotoxin ( , dotted line) andinthepresenceof neurotoxin and 50 lM dopamine (h, dashed line) • 1692 ... 1B shows the pattern seen after the development ofthe blot With increase in time of incubation, the intensity ofthe band for the monomeric protein decreased, whereas the bands for the higher...
... increase the amount of complex containing MT1MMP and furin, andthe expression of a catalytically inactive dominant negative furin construct affected the processing of pro-MT1-MMP Taken together, these ... sequence for the interaction with the PDZ proteins: Mint-3, AMPA binding protein and glutamate receptor interacting protein (GRIP) It would therefore be interesting to determine whether this motif ... the nature ofthe GRASP55 binding site inthe MT1-MMP ICD pACT plasmids driving the expression of MT1-MMP ICDs containing single-, double- and triple-point mutations were generated (Fig 4A) and...
... identify the site of action ofthe fatty acidsinthe plasmin molecule, the amidolytic activity of two truncated plasmin variants was examined (Fig 8) Miniplasmin (des-kringle 1-4 plasmin) contains the ... resulted in a decrease, of up to two-fold, inthe kp of plasmin Considering the recently described reversible nature ofthe plasmin inhibition by oleic acid [3] andthe changes ofthe kinetic parameters ... presenceof fatty acidsThe values of kp and Km were determined from the amidolytic assay of plasmin activity, according to Model I, inthepresenceof oleate (OA) and arachidonate (AA), or, according...
... documents the pattern of shifting individual actions, roles, and responsibilities in public space In all of these works, Arendt’s insistent appeal for thinking and seeing participation inthe world ... visitors to the site, individual decisions of these members ofthe public, andthe recycling of tiles placed inthe grid, to determine possible life spans of Limited Edition If not incal- Sculpture ... characteristics of life in Minnesota chronicled inthe musings of Garrison Keillor on his Prairie Home Companion, as well as in city branding initiatives The evolving collection of almost 200 audio and video...
... [21–25], and DGD° values inthepresenceof these osmolytes are given in Table However, DGD° values of RNase-A inthepresenceof alanine, serine, lysine, b-alanine, taurine and dimethylglycine have ... efficiency inthepresenceof this group of osmolytes Interestingly, there is a linear relationship between DDGD° and Dlog(kcat ⁄ Km) inthepresenceof methylamines and sugar However, the slopes ofthe ... have therefore measured the thermodynamic parameters of RNase-A inthepresenceof these amino acidsand amino acid derivatives, and values of DGD°, measured in triplicate, are given in Table The...
... and perinuclear areas ofthe cell via its N-terminal ABD Inthe absence of ligand, AR is localized predominantly inthe cytoplasm, and its hinge domain andthe LBD are tethered to the C-terminal ... FXXFF and FXXMF motifs and enhances its activity inthepresenceof androgen The interaction between the N- and C-termini ofthe AR does not affect gelsolin FXXFF binding to AR LBD, indicating ... ABPs in transcription regulation B Zheng et al Table Role of nuclear actin-binding proteins interacting with the androgen receptor AR, androgen receptor; LBD, ligand-binding domain Actin-binding...
... Knowledge and Skill Chains in Engineering and Manufacturing Figure The View andthe Scope Model of Cooling Service On the other hands, a scope model of a service represents the viewpoints ofthe service ... Knowledge and Skill Chains in Engineering and Manufacturing A platform independent model of an UMI includes a model ofthe persons and communities interacting in society Because quite a few of these interactions ... University, in Osaka carried the theme: “Enhancing Engineering and Manufacturing Knowledge and Skill Chains inthe era of Global Communications” The theme expresses both the wide scope andthe technical...
... These results are largely robust to including the proportion of Group pupils inthe surrounding area as the explanatory variable, rather than the total number of Group pupils inthe surrounding ... treatment in 1998 This was partly because of confusion inthe field about pupil age, and partly because inthe early stages ofthe program several ofthe Kenya Ministry of Health nurses administered ... charts, andthe training of teachers in each treatment school on worm prevention Health education stressed the importance of hand washing to avoid ingesting roundworm and whipworm larvae, wearing...
... neurons inthe brainstem and hypothalamus, and induce neuroendocrine and behavioral responses Food intake also activates the brainstem and hypothalamus, resulting inthe termination of meals andthe ... SP9155) Decrease in vasopressin release Increase inthe release of ACTH, oxytocin, vasopressin and prolactin Increase inthe release of ACTH, oxytocin and prolactin ? ? No effects Increase [52,53] ... hypothalamus The administration of RFRP increases Fos expression inthe hypothalamic paraventricular nucleus andin hypothalamic oxytocin neurons, and facilitates the release of ACTH and oxytocin into the...
... for the binding of calcium to G2 domain Footprint of G2 on gelsolin G4–6 domain Two sites within the G2 domain appear involved inthe G2- G4–6 interface inthepresenceof EGTA (Fig 3) The interaction ... actin-binding sites, is in interaction with the C-terminal a-helix of G6 domain The sequence 159–193, including the second actin interface, appears also in interaction with G6 domain Therefore, ... other domains until the gelsolin is fully ÔopenÕ, then additional calcium ions are required to bind actin to G1 and to G4 for severing and capping The details ofthe latch helix structure in the...
... one single object, inthe full sense, demands the compositive bringing into being of all these experiences in one act of manifold creation Therein it exceeds perceptual experience andthe synthesis ... unaccustomed position ofthe ngers makes the synthesis of their perceptions impossible: the right side ofthe middle nger andthe left side ofthe index not ordinarily work together, and if both are ... notion ofthe number six, the notion of side and that of equality, and link them together in a formula which is the denition ofthe cube But this denition rather puts a question to us than offers...
... instance, miR-373 induces the expression of E-cadherin and CSDC2 by targeting their promoter region and initiate their expression[73] Another mechanism is that the engagement of miRNA and their targets ... [21,43], if the function ofthe miRNA is dominant in leading the mRNA target degradation, however, most animal miRNAs pair to the 3' UTRs of their targets by incomplete base- pairing through their seed ... I6, H9 and BG01v are names of hES cells lines P denotes the number of passages ofthe cell lines H9-EB denotes embryoid body (EB) prepared from cell line H9 andthe day indicates the time in culture...
... stability depends on the characteristics ofthe visual environment, andofthe support surface, including the size ofthebaseof support, its rigidity or compliance [12,13] Within physiological ... young and old adults Aging affects the interaction ofthe somatosensory and visual systems on the ability ofthe CNS to resolve sensory conflicts and to maintain upright stance equilibrium Therefore, ... the decline inthe integrity of many postural regulating systems [14-16], but its effect on the sensory inputs recalibration process remains to be determined One question of interest is whether...