... cells increased and maintained a high level during the entire period of the culturing (data not shown) Considering that the same phenomenon could occur in vivo, we changed WT1 peptide administration ... prote ein have be een demonstrated to induce antigen-specif CTLs again a fic nst leukemia cel in preclini lls ical studies [10-13] Prelim minary clinical trials using peptide vaccines of the l ... syndrome (MDS) [7] In order to eradicate minimum residual CML cells which survived long-term imatinib therapy, we started WT1 peptide vaccination therapy in combination with imatinib in a CML patient...
Ngày tải lên: 26/10/2012, 09:39
... marking phrenic neurograms during eupnea To investigate the similarity between the patterns in the early and late phases of the phrenic neurogram during eupnea and the patterns during gasping, ... frequency of inspiratory neurons is unchanged during gasping but, unlike during eupnea, all inspiratory neurons fire simultaneously at the beginning of the inspiratory period during gasping [17] ... during maturation The dominant burst type activities disappeared during the early phase of the phrenic neurogram although the burst activity and the continuous activity remained, but both them...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo toán học: " Two-stage source tracking method using a multiple linear regression model in the expanded phase domain" pdf
... wrapping results in discontinuity due to the shifting phase term, ±2π given in Equation The purpose of phase expansion proposed in this article is recovering linear parallel lines by shifting ... signals in the original phase domain at 1500 Hz in dB SNR condition when true IPD is +2π/3 The IPD distribution in the original phase domain (dashed-line) is not symmetric and also a number of phases ... estimator since the Gaussian assumption for the IPD error, Equation 7, is valid in the expanded phase domain Finally, the estimator determines the most accurate delay among the estimated results in each...
Ngày tải lên: 20/06/2014, 20:20
Báo cáo y học: "Physical anhedonia in the acute phase of schizophrenia" doc
... of their hospitalisation by three independent psychiatrists-raters The first rater assessed the patients using the RPAS and the AIMS, the second using the PANSS and the EPSE and the third using ... schizophrenia regarding their medication status Second, there was a lack of a specific scale measuring depression in schizophrenia Third, we studied patients in the acute phase of their illness Hence, ... illness, at the Eginition Hospital, Department of Psychiatry, University of Athens, during a one-year period were studied Written informed consent was obtained from the subjects and their relatives...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt
... Based on the spatial and temporal levels of 40-kDa CSPGs in the injured spinal cord, injection into the injured spinal cord with chABC at the different time points post SCI was performed The hindlimb ... resolution in the alkaline ranges of IPGs [25,26] As shown in Figure 1B, the poor focusing for the three protein spots in 2DE could gain inaccurate quantification of their spot intensity Third, the ... downregulated in the LC in the subacute phase post SCI The reduction in these oxidoreduction-related proteins might be due to the extensive cell death occurring in the subacute phase However,...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Transcriptional control in the prereplicative phase of T4 development" pot
... with the mutant Rho promoting more termination In addition, expression of the Rop protein, an RNA-binding protein encoded by the pBR322 plasmid, also rescues T4 growth in nusD Taken together, these ... mutations in T4 that increase the synthesis of the early gene product rIIA [86] In fact, expression of several early genes increase in the T4 motA- infection, presumably because of a delay in the shift ... its termination activity [133,134] Sequencing of the rho gene in six nusD alleles has revealed that in five cases, the rho mutation lies within the RNAbinding site of Rho Furthermore, the addition...
Ngày tải lên: 12/08/2014, 02:20
Báo cáo y học: "Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock" potx
... affect the PK profile of these drugs during such severe infections Administration of the four β-lactams was made according to local guidelines These drugs are generally used in the participating ... strain) Piperacillin-tazobactam was preferred as first-line therapy in cases of proven or suspected intra-abdominal infections Ceftazidime and cefepime was used as first-line therapy in other ... before the infusion (0 hour) and 1, 1.5, 4.5, and or hours (depending on the frequency of administration of the β-lactam) thereafter; these blood-draw time points were chosen as they belong to the...
Ngày tải lên: 13/08/2014, 21:20
HOSM Driven Output Tracking in the Nonminimum-Phase Causal Nonlinear Systems
... without reducing the order of the input-output dynamics; • The causality of the output tracking in nonminimum phase system has been significantly enhanced due to allowing the output tracking profile ... robust to the external disturbances An engineering extension of the method introduced in [5] is studied in [12] Instead of asymptotic output tracking with complete stabilizing of the tracking error, ... nonlinear inverse in [16] and is accomplished using the sliding mode control technique in [6] Asymptotic output tracking for a class of nonlinear uncertain systems where the plant is presented in...
Ngày tải lên: 01/07/2015, 09:15
Combining DEMO models with RAD's techniques in the analysis phase of software development process
... of the related transactions Capturing the business processes of the organization, it can be used as the starting point to design the supporting system for the organization Combining with IAM, the ... By using above five steps, the IAM can be developed It can help to improve the operation of the organization by redesigning and reengineering the business In other words, before building an information ... requirements for the system Technique: The analysts fulfill the following table by using steps in the PM and requirements definition list There are six columns in the following table MAPPING TABLE Requirements:...
Ngày tải lên: 02/08/2015, 13:22
Synthesis of zr beta zeolite in fluoride medium and its applications in catalytic liquid phase reactions
... been achieved in the liquid phase The present industrial process involves the reaction of benzotrichloride (PhCCl3) with resorcinol in the presence of FeCl3 The limited space inside the H-beta pores ... to the higher degree of order in the absence of zirconium The incorporation of zirconium into the framework also induced the preference for the stacking sequence of polymorph B as observed in the ... particles They also found that the increase in the Al content accelerated the nucleation of zeolite beta from the amorphous solid gel These findings, however, are inconsistent with the conventional...
Ngày tải lên: 16/09/2015, 17:12
Fully automated plunger in needle liquid phase microextraction
... well as the pore of the fibre In the three -phase HF-LPME mode, analytes were extracted into the intermediary solvent phase in the pore of hollow fibre and then subsequently transfered into the aqueous ... Schematic of the PIN-LPME device in extraction step As shown in Figure 2-3, the continuous flow was formed by pumping the water sample from the reservoir into and out of the sample vial during the extraction ... as follow: The plunger wire was pulled back into the needle Then the needle was inserted into the solvent vial, which is placed in the agitator The plunger was pushed out to make the etched wire...
Ngày tải lên: 06/10/2015, 21:23
Development and application of liquid phase microextraction techniques in the analysis of environmental pollutants
... state, the diffusion coefficient in the aqueous phase increases with increasing stirring rate because faster agitation can decrease the thickness of the diffusion film in the aqueous phase Liquid- liquid ... to the protein film formed at the liquid- liquid interface were assumed to enhance mass transfer of analyte He and Lee introduced the term liquid- phase microextraction (LPME) [40] in 1997 They investigated ... amphetamines and phencyclidine in urine were investigated using LPME combined with GC analysis [57] The optimized method was capable of detecting drugs in urine at concentrations below the Substance...
Ngày tải lên: 17/09/2015, 17:20
Liquid phase microextraction for the determination of acidic drugs and beta blockers in water samples
... determines the feasibility of the extraction process; the higher DA1 the better the solute is being extracted into the organic phase On the other hand, stripping of analytes from the organic phase ... microextraction In three -phase LPME, the extraction process involves tandem reversible extractions In the first step, the analytes are extracted from the donor phase (sample phase) into the organic phase ... immobilized within the pores of the hollow fiber In the second step, the analytes are back-extracted into another aqueous phase held inside the lumen of the hollow fiber For analyte A, the extraction...
Ngày tải lên: 10/11/2015, 11:00
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... on the two further subunits of the native oxidase In focussing on the main interaction domain on subunit II, we introduced additional mutations in exposed residues in the relevant area above the ... position involved in maintaining the low residual activity when the W121 residue is mutated Double mutants in both positions are not further diminished in activity compared to W121 single mutations ... set of mutants in surface-exposed residues to further identify amino acid side chains involved in the docking of cytochrome c, or in the presumed electron entry from cytochrome c to the CuA center...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Thermal behaviour of cubic phases rich in 1-monooleoyl-rac-glycerol in the ternary system docx
... another way, with increasing temperature the bilayer gets thinner, with the minimal and the parallel surfaces of the polar/nonpolar interface approaching each other, again resulting in an increased ... obtained from the heating scan, again pointing to the difficulty of obtaining a true thermodynamic equilibrium for bicontinuous cubic phases 62 G Persson et al (Eur J Biochem 270) Similarly to the ... an increase in the size of the unit cell within a onephase area arises, and from the order of occurrence of the phases formed The reason for this change in the curvature can be understood in...
Ngày tải lên: 17/03/2014, 09:20
CHEMICAL REACTIONS IN GAS, LIQUID AND SOLID PHASES: SYNTHESIS, PROPERTIES AND APPLICATION pptx
... as the value of the induction period τ, were determined from the kinetic curves of oxygen absorption by method described in Ref 15 The interval from the beginning of the experience to the point ... literature data point to the fact that the presence of the C2 – C3 double bond in the C-ring caused the conjugation at all rings in the flavonoid molecule results in the increase of their antioxidant ... after the complete consumption of InH The second line is tangent to the kinetic curve of the oxygen uptake in the point, the reaction rate of which is twice less than that in the absence of inhibitor...
Ngày tải lên: 28/03/2014, 10:20
The Local Benefits of Global Air Pollution Control in Mexico City - Final Report of the Second Phase of the Integrated Environmental Strategies Program in Mexico ppt
... and their staffs in Mexico City There is interest from these groups in applying the model to their work and in modifying it for use in other regions of Mexico, particularly the City of Toluca in ... over the time period of the analysis, including the program would restrict a growing number of vehicles in the baseline according to an increasing emissions 35 deterioration By contrast, when these ... al., 2002) One should therefore be cautious in the interpretation of the results from the present analysis 27 III.2.4 Determining baseline emissions Following the emissions inventory (CAM, 2002a),...
Ngày tải lên: 29/03/2014, 14:20
Air Pollution Control in the Transportation Sector: Third Phase Research Report of the Urban Environmental Management Project pdf
... presented in the Final Chapter.1 The UE Project held two workshops to discuss the progress of the case studies and their policy implications in July and September of 2006 in Hayama The findings of the ... role in achieving this Since the majority of Asian countries are adopting existing technology rather than creating new technology, one of the central tasks in developing urban transport is finding ... about 0.56 gm/L in 1994 Since then Lead has been phased out from gasoline in India From February, 2000, only unleaded gasoline is sold in the entire country The sulphur content in diesel has been...
Ngày tải lên: 29/03/2014, 14:20
phase equilibria and fluid properties in the chemical industry estimation and correlation
... between academic and industrial engineers and whether the ideas expressed influence research in the coming years xii In Phase Equilibria and Fluid Properties in the Chemical Industry; Storvick, ... because there were obvious dislocations between the current needs of the industrial chemical engineer and the research being done at universities, on the one hand, and the slow acceptance of new theoretical ... was founded in 1974 to provide a medium for publishing symposia quickly in book form The format of the SERIES parallels that of the continuing ADVANCES IN CHEMISTRY SERIES except that in order to...
Ngày tải lên: 02/04/2014, 16:19
Annuities and Other Retirement Products: Designing the Payout Phase (Directions in Development)_1 doc
... compare them OO The call buyer has the right to buy the underlying, consequently the call seller may have the obligation to sell the underlying OO The put buyer has the right to sell the underlying, ... have the obligation to take a long position in the underlying If these statements seem confusing, bear in mind that they are related to each other by simple logic: if one is true, then the others ... rises, the price of the futures contract decreases An investor wishing to hedge a rise in the interest rate to per cent could pay 0.02 for the 94.00 put An investor wishing to hedge a fall in the interest...
Ngày tải lên: 21/06/2014, 07:20