adviser dialogues1 evidence for sufficiency of restricted language sinnatural language interfaces

... While formality and completeness of typed user -adviser dialogues resemble more Formal Written language, the general syntactic features of typed user -adviser dialogues resemble more Informal ... user -adviser dialogues have some features of planned, Formal Written language but also have features of unplanned, Informal Spoken language. Table 4: Distribution of Propositional Attachments CtHmp~x ... Academic Press. Sager, N. (1982). Syntactic Formatting of Science Infor- mation. In R. Kittredge -~ J. Lehrberger (Eds.), Sublanguage: Studies of Language in Restricted Semantic Domains. New York:...

Ngày tải lên: 08/03/2014, 18:20

... coupling constant of the spectrum of the turnover form of the T2Cu center are slightly different from that of the as-purified form (cf. Table 2) which suggests the existence of modifications in ... recent model for the catalytic mechanism of Cu-Nir supposes that nitrite binds to the oxidized form of the T2Cu center, displacing a solvent molecule and forming a hydrogen bond between one of its ... 1.7.2.1). *Present address: Institute of Pharmacology and Therapeutics, Faculty of Medicine of Porto, and Institute for Molecular and Cell Biology, University of Porto, Alameda Prof. Hernaˆ ni Monteiro, 4200–319...

Ngày tải lên: 07/03/2014, 15:20

... the event of metal ion donation will be of significant value for understanding the role of MT in the cellular meta- bolism of Zn 2+ . Despite the relatively large thermo- dynamic stability of the ... side of Fig. 3 clearly show the formation of inter- mediate Cd 1 a,Cd 2 a and Cd 3 a species, with the Cd 4 a species forming only after > 3 equivalents of Cd 2+ have been titrated. Addition of ... fold- ing of MT results in the formation of discrete metal– thiolate clusters within each of the a and b domains with stoichiometries of [M 4 (S cys ) 11 ] and [M 3 (S cys ) 9 ], respectively, for...

Ngày tải lên: 19/02/2014, 00:20

... is beginning to be perceived. For instance, one striking example of c-Src location inside one organelle has been reported for the inner mem- brane of mitochondria of osteoclasts [57]. Moreover, there ... In Madin–Darby canine kidney (MDCK) cells, a study of chimeric forms of DPP IV has shown that the luminal domain of DPP IV carries dominant apical sorting information while the short cytoplasmic tail ... concentration of the soluble form of DPP IV may result in an increased proteolysis of GLP-1 peptides and thus decreased insu- lin secretion [20]. The insulin-dependent phosphoryla- tion of DPP IV...

Ngày tải lên: 19/02/2014, 07:20

... spans of TatA and TatB Deletion of the TM spans of TatA or TatB leads to a loss of activity [31] but the important characteristics of these regions have not been probed. We constructed a series of ... 2267 Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase Claire M. L. Barrett and Colin Robinson Department of Biological ... effects of substituting groups of basic residues in these regions of TatA and TatB [24]. The present study has increased our understanding of this region in two ways. First, the removal of three...

Ngày tải lên: 19/02/2014, 17:20

... </number> </MorphoFeat> </hasMorphoFeat> </InflectedForm> </hasInflectedForm> <hasInflectedForm> <InflectedForm rdf:ID="star"> <hasMorphoFeat> <MorphoFeat ... </number> </MorphoFeat> </hasMorphoFeat> </InflectedForm> </hasInflectedForm> </LemmatiedForm> Figure 2: Formalization of the morphological layer and excerpt of a sample ... be a conjunction of Ew i and Ew j , and the counterpart is the intersection of set of translations for each language. This oper- ation would reduce the number of words of each language. That means,...

Ngày tải lên: 20/02/2014, 12:20

... conducted in the absence of Tween 80. Finally, in the presence of Tween 80, oxidation of a-keto diarylpropane (X) resulted in the formation of 3,5-dimethoxybenzoic acid (XII, 5.0%) ... Oxidative decomposition of malonic acid as basis for the action of peroxidase in the absence of hydrogen peroxide. FEBS Lett. 434, 362–366. 292 G. V. B. Reddy et al. (Eur. J. Biochem. 270) Ó FEBS 2003 Cleavage of ... aromatic ring to form an aryl cation radical [3,11,15,16]. Chemical and ESR spectroscopic evidence have confirmed the formation of cation radical species in the LiP-catalyzed oxidation of alkoxybenzenes...

Ngày tải lên: 20/02/2014, 23:20

... methylation of the C-terminal half of the a1(I) resulted in either reduced binding for a1(I) CB7, or a complete l oss of the binding for a1(I) CB6. The variation of the binding ability for N-methylated ... were analyzed for purity by means of a quantitative Hyp assay [38], electrophoresis in denaturing conditions [34], N-terminal sequencing for some peptides and for conformation by means of CD spectro- scopy. Chemical ... Role of decorin on in vitro fibrillogenesis of type I collagen. Glycoconj J. 14, 871–874. 33. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein...

Ngày tải lên: 21/02/2014, 15:20

... were subjected to one cycle at 95 °C for 2 m in; 40 cycles at 95 °Cfor30s, 60 °C for 60 s and 72 °C for 90 s ; and a ®nal additional extension period at 72 °C for 5 m in. Ampli®ed DNA fragments ... 2002 understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nes involved in the biosynthetic pathway c an certainly provide valuable information. In ... activity of this mutant enzyme could not be restored by the addition of Tween 40 [39], i t can be concluded that the 482 Gly residue is important for the activity of the enzyme, likely being one of...

Ngày tải lên: 22/02/2014, 04:20

... literature, espe- cially for more advanced stages of melanoma [179] (see Table 7). An Italian cohort of 8,984 women was followed for an average of 9.5 years, with 207 incident cases of breast cancer ... increased risk of colorec- tal cancer [30]. In a study of a cohort in Washington county, Maryland, increased risk of colorectal cancer was BioMed Central Page 1 of 21 (page number not for citation ... vitamin D, 25(OH)D, into the active hor- monal form, 1,25(OH) 2 D. So, there is a local mechanism in many tissues of the body for converting the form of vitamin D in the body that is elevated by...

Ngày tải lên: 06/03/2014, 02:21

... properties, providing kinetic evidence for the direct complex formation of P450nor with NADH. Materials and methods Mutagenesis and expression plasmids The construction of each mutant of P450nor of F. oxyspo- rum ... omposition of I that follows its formation, although the rate of decomposition is m uch slower than that of I formation (cf. Figure 6). Fig. 5. Saturation kinetics observed o n the reduction (I formation) ... eduction of the D393A mutant is performed with NADH at a higher con centration, the formation of I should be more complete, affording a clearer isosbestic point. Saturation kinetics of the intermediate...

Ngày tải lên: 07/03/2014, 15:20

... promis- cuous receptor. Evidence for the conservation of the mechanism of mesoderm induction in molluscs and across bilaterians Although Lartillot and colleagues have observed for a number of developmental ... Marseille) for provision of the pRN3 plasmid. We acknowledge J. Laisney and A. H. Hansen for their technical assistance. We also thank Prof Manfred Schartl (Physiological Chemistry I, University of Wuerzburg, ... major group of bilaterian animals, have remained in the background of the molecular survey of metazoan development. We report the cloning and functional study of the central part of the BMP pathway...

Ngày tải lên: 07/03/2014, 21:20

... the carbonyl oxygen of G168. Inclu- sion of F221 obscures the local structure in the proximity of T171 and for clarity is omitted. Table 1. Comparison of functional parameters for HRPC proximal pocket ... type [16,17]. The pK a for the alkaline transition being similar to that of the wild type, % 11.1 [18]. Finally, comparison of the X-ray structures of the oxidized forms of the native [5,19] and ... state of the enzyme. We hypothesize that this residue imposes a degree of rigid- ity to the structure of the reduced state of class III peroxidases. Results and Discussion Table 1 shows some of...

Ngày tải lên: 07/03/2014, 21:20

... Barbanti-Brodano, G., Russo, G. & Negrini, M. (2000) Low frequency of alterations of the a (PPP2R1A-) and b (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms. ... reaction was performed using primers containing the translation stop of the different isoforms to obtain specific cDNA. After purification of this cDNA, semiquan- titative PCR was performed. PCR products ... & Goris, J. (1995) Molecular cloning and developmental regulation of expression of two isoforms of the catalytic subunit of protein phosphatase 2A from Xenopus laevis. Biochem. Biophys. Res. Commun....

Ngày tải lên: 08/03/2014, 08:20

... preferences of the lectins for agalactosylated N-glycans. The specificity to agalactosylated N-glycans should help our understand- ing of the previously unknown mechanism of the func- tions of the ... the absence of DC-SIGN–Fc. As shown in Fig. 9B, the three major bands (i.e. 1, of 160 kDa; 2, of 75 kDa; and 4, of 55 kDa) were present on a silver-stained gel, as well as an extra band (band 3, of 65 ... the DC-SIGN-related lectins for PA-glycans. Fig. S1. Schematic representation of 157 oligosaccha- ride structures used for FAC analysis. Fig. S2. Structural formulae of Man 9 GlcNAc 2 -MTX, Mana1-3Man-PA...

Ngày tải lên: 15/03/2014, 23:20

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