... specific for adverse drug reactions where toxicity is the underlying cause, many adverse drug reactions are not related to toxicity In fact this is particularly true with vaccines where the adverse ... health care professionals to report serious and unexpected suspected adverse reactions and adverse reactions in humans exposed to veterinary medicinal products to the regulatory authorities In doing ... levels Phytotoxicity Invertebrate toxicity Vertebrate toxicity Target Animal Safety: Clinical trials Laboratory studies Tolerance studies Environmental Safety Efficacy: Clinical trials Laboratory...
Ngày tải lên: 06/03/2014, 16:20
... for achievement, the ability to have motives to carry out an action, and self-monitoring (Ellis, 1988) Once again, these traits were thought to be inborn, and unique to leaders Trait theories were ... rejection (Bass, 1960, 1990) An autocratic leader was also defined as a person who used power to be strict rather than lenient, to supervise closely, and to ensure adherence to procedures (Blau and Scott, ... proposed Firstly, ‘‘autocratic leaders’’ were originally described as leaders who used their power to force, or their ability to persuade in leading their followers A powerful autocratic leader influenced...
Ngày tải lên: 08/10/2013, 15:56
Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... balance to total capital, total assets and deposit balance have also increased At the end of June 2003, total assets of foreign banks amounted to USD41.25 billion and total loan balance amounted to ... financial sector They help to mitigate financial repression in China, to establish sound financial system, to enlarge contribution of the financial sector to economic development and to realize ... the financial sector The relationship between financial opening and financial security China’s decision to join the WTO signifies a step forward in the opening of financial sector to the outside...
Ngày tải lên: 18/10/2013, 07:15
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... suspected adverse reactions to BCG vaccination (Table 1) should be reported to the manufacturer and to the Vaccine Adverse Event Reporting System (VAERS); telephone (800) 822-7967 These reactions ... inquiries about the MMWR Series, including material to be considered for publication, to: Editor, MMWR Series, Mailstop C-08, CDC, 1600 Clifton Rd., N.E., Atlanta, GA 30333; telephone (404) 332-4555 ... nonreactive to tuberculin Responsiveness to tuberculin or other delayed-type hypersensitivity (DTH) antigens may be decreased in persons infected with HIV; this anergy (i.e., the inability to react to...
Ngày tải lên: 15/02/2014, 13:20
Tài liệu The Role of Community Banks in the U.S. Economy pdf
... test because they are too new to have established credit histories or because their owners have too few personal assets to offer as collateral Community banks should continue to have an inherent ... investors to buy and sell individual stocks on the Internet Most of these companies also allow their online customers to shift funds among a wide variety of investment vehicles, including stock ... Hunter) According to this view, community banks can use the Internet to offer greater convenience and choice of financial service to their customers, while continuing to provide person -to- person contact...
Ngày tải lên: 16/02/2014, 11:20
Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... resistance to the cytosolic RNase inhibitor RNase catalytic activity is an absolute requirement for the cytotoxic action of all cytotoxic RNases tested [5] Moreover, when the effects of cytotoxic ... were studied, cytosolic rRNA [18] or tRNA [19] were found to be the targets of cytotoxic RNases Thus, we can conclude that to exert its cytotoxic action, an RNase must reach the cytosol Furthermore, ... its resistance to the cytosolic ribonuclease inhibitor Biochemistry 40, 3492– 3496 Monti DM & D’Alessio G (2004) Cytosolic RNase inhibitor only affects RNases with intrinsic cytotoxicity J Biol...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... transfectants In order to produce stable transfectans, each plasmid DNA (2–4 lg) was transfected into · 105 CHO cells using the Eppendorf Multiporator and an appropriate Eppendorf protocol (Wesseling-Berzdorf, ... Yamamoto M & Saito N (1995) Immunocytochemical localization of three subtypes of GABA transporter in rat retina Brain Res Mol Brain Res 33, 319– 325 10 Bennett ER & Kanner BI (1997) The membrane topology ... were normalized to the transporter proteins in the plasma membrane, the reduced specific activities of the mutants are not due to a reduced number of GABA transporters per cell, but to a reduced...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx
... not in pathological behavior is used to further understanding of the behavior and to suggest evolutionary changes in the model to better its approximation to languageprocess Information is presented ... natural language systems for speech recognition comprehension and automatic translation into French One issue, how to chunk French into a phonetic representation of words, along with the implications ... word in sentence the the POST-REFRACTORY-STATE-ACTIVATION: An automatic change of state which a l l fired information enters after i t has existed in the REFRACTORY-STATE The decay rate is d i f...
Ngày tải lên: 21/02/2014, 20:20
Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... internal adjustment than to exogenous characteristics: this group includes, inter alia, a large proportion of firms belonging to the energy sector Groups (bottom-left quarter) and (top-left quarter) ... Expected Debt (Ordered-Probit) Explanatory Variables f2 0,3270 (2,294) Explanatory Variables f2 0,6007 (2,076) Explanatory Variables f2 No-debt A: Total Sample Inventory Exp-prod Labour Khi(2) 1,51 ... started to surface at the end of 1997, and became generalised during spring 1998, was doomed to have only a limited direct impact on the real sector, unless it extended to the foreign exchange or to...
Ngày tải lên: 06/03/2014, 08:20
BEYOND MICROCREDIT: THE ROLE OF SAVINGS BANKS IN MICROFINANCE potx
... banks is to reposition towards low-risk retail banking activities and not to become pure microfinance institutions or microfinance banks There are diverse business models to respond to the pressing ... 2006 26 TOWARDS AN ENABLING REGULATORY AND SUPERVISORY FRAMEWORK Microfinance is one of many tools for expanding access to financial services Therefore, any policy, legislative or regulatory initiative ... savings bank with the mission to cater to the financial needs of low-middle income clients and microenterprises n The Cajas de Crédito, today represented by FEDECREDITO in El Salvador, started operating...
Ngày tải lên: 06/03/2014, 10:20
THE ROLE OF MUSIC COMMUNICATION IN CINEMA potx
... understood to be heard by characters in the narrative – including music – are referred to as diegetic, while those that are not part of the diegesis (e.g., the orchestral score) are referred to ... consistent with one another To apply this test to a motion picture, one would ask “Is the same information being presented via both the auditory and visual modalities?” To use Cook’s terminology, ... will use the term “director” as a metonymy for the complex collaboration and decision-making process involving composer, sound designer, screenwriter, editor, and director … but which is ultimately...
Ngày tải lên: 07/03/2014, 14:20
Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... residue needs to be protonated, but subsequently it needs to make this proton acidic to promote leaving group departure As explained above, it is conceivable that rotation of protonated Asp142 ... proton shared by Asp140 and Asp142 in the apoenzyme remains on Asp142 when this residue moves to a position close to Glu144 It is conceivable that the presence of the protonated Asp142 close to ... the E144Q mutant with (GlcNAc)5 bound to subsites )2 to +3 (PDB accession code 1E6N [21]) Prior to some of the calculations one or more adjustments were made to the structures, as listed in Table...
Ngày tải lên: 07/03/2014, 14:20
Báo cáo khoa học: "The Role of Information Retrieval in Answering Complex Questions" ppt
... employed to improve performance (Salton and Buckley, 1990) Following settings in typical IR experiments, the top twenty terms (by tf.idf value) from the top twenty documents were added to the original ... recognition, which have worked well for factoid questions, are not applicable to relationship questions, since answer types are difficult to anticipate For factoids, there exists a significant amount ... introduction of this automatic scoring technique, studies such as this were difficult to conduct due to the necessity of involving humans in the evaluation process P OURPRE was developed to enable rapid...
Ngày tải lên: 08/03/2014, 02:21
The Role of Rainfed Agriculture in the Future of Global Food Production doc
... countries are projected to increase from 1.5 metric tons per hectare to 2.1 metric tons per hectare by 2021-25, and rainfed area in developing countries will account for 43 percent of total cereal area, ... 20.1 million metric tons in China, 18.4 million metric tons in India, 18 million metric tons in WANA, 1.6 million metric tons in developed countries, and 53.0 million metric tons in developing ... techniques are used to increase rainfed cereal yields Three major breeding strategies include research to increase harvest index, to increase plant biomass, and to increase stress tolerance (particularly...
Ngày tải lên: 09/03/2014, 00:20
The Role of Postal Networks in Expanding Access to Financial Services docx
... are less likely to financially support (or be able to) the national postal operator in favor of private-sector competitors It also implies the need to improve cost accounting to distinguish between ... to financial services The landscape is intended to serve as a basis to assess the potential role to expand access to financial services For some aspects and some countries data did not seem to ... only to the medium and higher income groups A policy to improve access to financial services would have to start by offering a very broad section of the population access to In Expanding Access to...
Ngày tải lên: 15/03/2014, 10:20
The Role of Bank Capital in the Propagation of Shocks potx
... and monitoring entrepreneurs However, bank monitoring is privately costly and without proper incentives, banks may not provide the correct level of monitoring To give them the incentive to so, ... and their investors A bank that pledges its own net worth reduces moral hazard because it has an incentive to adequately monitor the entrepreneurs it finances Investors thus seek to invest funds ... their capital stock) equals total demand from intermediate-good producers Equation (47) requires that the total supply of the composite labour input produced according to (28) equals total demand...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf
... around v1 relative to the A-form and was exposed to the solvent The two oxygen atoms of the Glu526 side-chain in the A-form were positioned close to the proximal glycosidic oxygen atom (O1) at dis˚ ... acts to restrain the Glu526 sidechain into the A-form by hydrogen bond interaction, promoting Glu526 to donate a proton to a proximal glycosidic oxygen atom The D524A–substrate complex is unique ... Glu (E) in this motif acts as the catalytic proton donor, and the second Asp (D2) is supposed to contribute to the stabilization of the essential distortion of the substrate [24] We have reported...
Ngày tải lên: 15/03/2014, 11:20
The Role of Tradable Permits in Water Pollution Control doc
... Agreement According to the Agreement, a 40% reduction of 23 nutrients, compared to 1985 levels, in the Bay is necessary to restore its health by the year 2000 (Wiedeman, 2001) New restoration commitments ... from command-and-control to various market-based instruments in order to achieve further water pollution control This is partly due to the fact that the cheapest and easiest -to- achieve point source ... easiest -to- achieve point source reductions have occurred via regulatory command-and-control instruments, leading now to an escalation of costs to meet tougher water quality standards Moreover, non-point source...
Ngày tải lên: 15/03/2014, 16:20
THE ROLE OF BIODIVERSITY CONSERVATION IN THE TRANSITION TO RURAL SUSTAINABILITY pptx
... transition to sustainability means coping with persistent periods of disequilibria It will be tempting to return to the current repertoire tools for problem solving, but people will increasingly turn to ... twentieth century; our tools are better than we are, and grow faster than we They suffice to crack the atom, to command the tides But they not suffice for the oldest task in history; to live on a piece ... damage and harm to third world farmers Total support to agriculture amounted to US$ 311 billion, while support to agricultural producers accounted for 31% of total farm receipts in the OECD area...
Ngày tải lên: 15/03/2014, 18:20
The Role of Investment Funds in Romania pptx
... capitalization of the SIFs in total capitalization remained relatively constant, this is not due to their performance, but to the stock market decline, which led to lower total market capitalization ... access to certain databases, have the ability to harness and interpret in a superior way the information So, they are transforming them into profitable investment process for both investors and ... in touch, on one hand with the higher yield of the bonds funds (of maximum 14,5% in 2009 and 11,79% in 2010 according to Aviva Investors Romania, 2010) and on the other hand with the investors’...
Ngày tải lên: 16/03/2014, 17:20