advances in magnetic resonance imaging of multiple sclerosis

... Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer ... Replicating viruses WT -Replicating wild type virus WT-RGD -RGD insertion in HI loop of fiber knob for avb integrin targeting [43] WT-RGDK -Fiber shaft’s KKTK domain mutated to RGDK for avb integrin ... plaque forming unit incision Tumors were established by intrasplenic injection of × 10e6 HCT116 cells suspended in 50 μl of serum-free growth media using a 27-gauge needle The injection site of the...

Ngày tải lên: 18/06/2014, 16:20

... observed, corresponding to the acute inflammatory phase of the disease [62] Interestingly, we did not observe any changes in the number of infiltrating lymphocytes in the spinal cord of diazoxide-treated ... in pancreatic beta-cells, where an increase in plasma glucose promotes a calciumdependent release of insulin due to the closing of KATP channels as a result of glycolysis-mediated increases in ... lymphocytic infiltration into the spinal cord during EAE To determine whether diazoxide treatment affected T and B lymphocyte infiltration into the spinal cord of EAE mice, immunoflorescence using anti-CD3...

Ngày tải lên: 19/06/2014, 22:20

... into microfuge tubes for imaging One example of the MR images is shown in Figure In MRI, the signal recorded during the scan is related to the magnetic relaxation processes of the nuclear spins ... images of aqueous samples of varying concentrations with the units of mM While a dose-dependent increase in signal intensity is seen in the T1 measurements, a dosedependent decrease in signal intensity ... nuclear spins of the protons in the water molecules in the area of interest Under a given external magnetic field (B), the nuclear spins of the protons align with the field, giving rise to a...

Ngày tải lên: 20/06/2014, 23:20

... Felson DT: The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee J Bone Joint Surg Am 2003, 85A:4-9 Link TM, Steinbach LS, Ghosh S, ... radiological evidence of OA of the affected knee on a radiograph obtained within six months of the outset of the study Finally, patients had to have a minimum JSW of the medial compartment of between and ... contraindication to the use of MRI Further exclusion factors included patients' history of past or present gastrointestinal ulceration, their receipt of an intraarticular corticoid injection in...

Ngày tải lên: 09/08/2014, 07:20

... estimation of ICP and to define thresholds for diagnosing intracranial hypertension In our institution, brain MRI studies are performed for research purposes during the acute phase of traumatic brain injury ... is of interest In humans, noninvasive assessment of ICP using ocular sonography and ONSD measurement has been proposed in cases of hydrocephalus, hepatic failure and TBI [8,10,31-36] Interestingly, ... Potential heating caused by intraparenchymal intracranial pressure 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 transducers in a 3-tesla magnetic resonance imaging system using a body radiofrequency...

Ngày tải lên: 13/08/2014, 11:22

... normal on detail clinical examination Exclusion criteria included history of back injury, weakness or numbness in one or more limbs, urinary incontinence or nocturnal enuresis None of the subjects ... lungs and summing crossMeasurement ofof delineating the a semi-automated compuMeasurement of lung volumes by a semi-automated computerized method of delineating the lungs and summing crosssectional ... ascending order of effort Score 4–6 was equivalent to feeling of breathlessness during exercise activities in ascending order of severity Score 7–9 was equivalent to feeling of breathlessness...

Ngày tải lên: 20/06/2014, 01:20

... Although the implications of having a small sample size pertains to generalisability of these findings, our findings are in concordance with previous neuroimaging studies in POCs with very small ... periods of sustained attention In the POCs, significantly increased activity was found in the following regions during sustained attention trials compared to rest (listed in descending order of size): ... left side of the images In the POCs, dual attention (vs rest) was associated with increased BOLD activity in the following (listed in descending order of size): bilateral cingulate gyri, R inferior...

Ngày tải lên: 08/08/2014, 23:21

... to the inflammatory and structural findings Readers agreed on the presence of inflammation at any site in 85% of the cases in the right SI joint, and in 78% of the cases in the left SI joint Kappa ... because of the availability of effective treatment Magnetic resonance imaging (MRI) is an imaging modality that may shorten the delay between the start of symptoms and a classifying diagnosis of AS ... reflecting the agreement for detecting inflammation were reasonable (right SI joint, 0.68; left SI joint, 0.51) Table also provides insight into the prevalence of the various findings in this...

Ngày tải lên: 09/08/2014, 07:20

... [4] included 15 PsA patients in their study of MRI, ultrasound and scintigraphy of the finger joints, nine of whom were described as having MRI erosions Some of these were ‘nonenhancing’ following ... common in SpA, most often involving the dorsocaudal part of the joint in early disease in which subchondral bone oedema was a frequent finding Figure shows an example of MRI sacroiliitis in a patient ... enthesopathy in 17 early SpA patients (including four with PsA), and similar findings were described, again often including underlying bone marrow oedema [15] However, Jevtic and coworkers [12], describing...

Ngày tải lên: 09/08/2014, 07:20

... Figure Negative correlation of bone marrow edema in histopathological assessment and magnetic resonance imaging (a) Magnetic resonance imaging of imaging zygapophyseal joints (cyan arrows) without ... marrow edema in histopathological assessment and magnetic resonance imaging (a) Magnetic resonance imaging (T2 imaging sequence) of a zygapophyseal joint with bone marrow edema (cyan arrow) (asterisk, ... assessment of zygapophyseal joints (a) Macroscopic picture of a zygapophyseal joint from a patient with ankylosing joints spondylitis (AS) (b) Hematoxylin and eosin staining of a zygapophyseal joint...

Ngày tải lên: 09/08/2014, 08:22

... severity of symptoms, including worsening of pain at 24 months Competing interests JFB, GAC, and JMM declare that they have financial competing interests as employees of and/or holders of stocks ... of the number of patients to be included in a clinical trial It also raises the important issue of the relevance of performing patient stratification at baseline during clinical trials Our findings ... [4-7] In the last decade, remarkable progress in the development of imaging technology has been made Magnetic resonance imaging (MRI) now allows not only the direct visualization of joint structure...

Ngày tải lên: 09/08/2014, 10:20

... tool increasingly used by clinicians, including rheumatologists, but the US data on small joints in PsA are very limited [8,9]; in particular, the validation of the findings is minimal The aim of ... and of the 3rd distal interphalangeal joint of a patientresonance imaging (MRI) and ultrasonography (US) in longitudinal dorsal (d) and palmar (e) views of the 3rd distal interphalangeal joint of ... or absence of aforementioned changes by a radiologist experienced in musculoskeletal radiography (MH), who was blinded to clinical and other imaging findings Magnetic resonance imaging parameters...

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 09/08/2014, 10:22

... measurement of magnetic resonance imaging erosion volumes in patients with rheumatoid arthritis: a comparison with existing magnetic resonance imaging scoring systems and standard clinical outcome ... change of magnetic resonance imaging and radiographic scoring of structural joint damage in rheumatoid arthritis finger, wrist, and toe joints: a comparison of the OMERACT rheumatoid arthritis magnetic ... evaluation of magnetic resonance images, and was involved in patient recruitment MH was involved in the CT scanning protocol EN performed the evaluation of radiographs JM was involved in the MRI scanning...

Ngày tải lên: 09/08/2014, 10:23

... mouse models List of abbreviations MRI: magnetic resonance imaging; BT-MRI: benchtop -magnetic resonance imaging; NMR: nuclear magnetic resonance; Gd-BOPTA: gadobenate dimeglumine; s.c.: subcutaneous; ... weekly For histological examination tumors were explanted, fixed in 4% formalin and embedded in paraffin Hematoxylin/Eosin staining of slices was performed according to standard protocols All ... Woolliscroft MJ, Rehemtulla A, Ross BD, Holland EC: Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma Clin...

Ngày tải lên: 10/08/2014, 10:21

... Jalal et al.: Contribution of magnetic resonance imaging in the diagnosis of talus skip metastases of Ewing’s sarcoma of the calcaneus in a child: a case report Journal of Medical Case Reports 2011 ... extraosseous soft-tissue component and often sclerotic reaction [5,6] In spite of clinical and radiological findings, Ewing’s sarcoma can be misinterpreted as osteomyelitis, cartilaginous tumor, ... may be pulmonary involvement, bone or bone marrow spreading, skip metastases, or combined metastatic disease [7,9] The imaging features of local spread of Ewing’s sarcoma, involving small bones...

Ngày tải lên: 10/08/2014, 23:20

... Blue staining in MSCs incubated with FePLL for 24 hrs Note that virtually all cells display blue intracellular staining (B-F”) Representative images showing dextran immunostaining (green) in MSCs ... Fleischmann BK, et al: Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat Proc Natl Acad Sci USA ... Alizarin Red staining for 30 minutes in water All reagents used in this experiment were from Sigma-Aldrich Co Page of 13 micromass cultures, the cells were seeded in μl droplets in the center of...

Ngày tải lên: 11/08/2014, 00:22

Ngày tải lên: 11/08/2014, 00:23

... one of the MR imaging characteristics of ganglioneuroma is curvilinear bands of low signal intensity on T2-weighted images [7], which were absent in the current soft-tissue perineurioma The soft-tissue ... tomography and magnetic resonance imaging findings of soft tissue perineurioma Radiat Med 2008, 26:368-371 Rha SE, Byun JY, Jung SE, Chun HJ, Lee HG, Lee JM: Neurogenic tumors in the abdomen: ... diagnosis of soft-tissue perineurioma requires biopsy and immunohistochemical reactivity evaluation, the CT and MRI findings described in this report suggest inclusion of this rare tumor in the...

Ngày tải lên: 11/08/2014, 03:21