... 1999): … just as risk management has been an inherent form of mining activities over the years, so has some implicit form of risk assessment What is new is the formalisation of risk assessment and ... part of a bricolage of explanations offered by official regulatory websites in a number of countries to account for the move to risk based regulation Canadian documents for example link risk based ... which is based in the Cabinet office and demands that proposals for new regulations are subject to a regulatory impact assessment which assesses the impact of policy options in terms of the costs, ...
Ngày tải lên: 23/03/2014, 00:20
... plates that will later be used for the assays However, one of the limitations of the microplate-based binding assay is that it is only suitable for a small amount of cells in 96-well or 24-well ... containing unit of polymerase (New England Biolabs, Beverly, MA, USA), 0.4 lm each primer, and lL of human lung cDNA, for 30 cycles of 98 °C for min, 60 °C for min, and 72 °C for The amplified ... temperature cycling (95 °C for 30 s, 53 °C for 30 s, and 68 °C for 13 min) for a total of 25 cycles, with an additional extension cycle of 68 °C for 10 min, using Pfu DNA polymerase from Stratagene...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt
... position of mannose is drawn in light green, as is the corresponding orientation of the side chain of Glu221 The second conformation of the side chain of Glu221, which also adopts two conformations ... and not a consequence of the correlation of fitting parameters often observed for weak binding events Evidence for this stems from the reproducibility of this result as well as from the c-value ... (A) Electron density for the pentasaccharide M592 in the binding site of subunit B of PAL The map is calculated and drawn as in Fig (B) Interactions of M592 with PAL The pentasaccharide is shown...
Ngày tải lên: 23/03/2014, 11:20
also, what kind of trade policy do you think should the government adopt for the benefit of the country as whole
... pays for suppliers They must pay a higher price for imported product TO CONSUMERS The tariff affords producers some protection against foreign competitors by increasing the cost of imported foreign ... CONSUMERS The tariff affords producers some protection against foreign competitors by increasing the cost of imported foreign goods TO PRODUCERS TO WHOLE COUNTRY The tariff increases the government ... Mercantilism makes a crude case for government involvement in promoting exports and limiting imports • The theory of Smith, Ricardo, Heckscher – Ohlin from part of the case for unrestricted free trade...
Ngày tải lên: 12/07/2014, 14:18
Báo cáo y học: "Clinical guidelines for the recognition of melanoma of the foot and nail unit." doc
... The prognosis for melanoma corresponds to the histological (Breslow) thickness of the excised tumour This represents a measure of depth of invasion of the tumour into the dermis For example, a ... stands for Extension of the pigment onto the adjacent skin or nail fold, known also as Hutchinson’s sign and F stands for Family history of melanoma or dysplastic naevus All these points are reasonable ... should be reassessed, and referred if considered appropriate Page 12 of 13 10 11 12 13 14 15 16 Consent Written informed consent was obtained from the patient for publication of this case report...
Ngày tải lên: 10/08/2014, 21:24
Structure basis for molecular recognition of folic acid by folate receptor
... of folate in de novo synthesis of nucleotides, antifolate has been used in the treatment of a number of carcinomas In addition, antifolate is also used in autoimmune disease treatment, such as, ... developed for anticancer treatment [68] A second generation of GARFT inhibitor was synthesized based on the studies of lometrexol AG2034 was designed using the knowledge of crystal structure of E.coli ... 1298A>C, has been found to be associated with reduced enzyme activity and increased risk of NTDs with no effect on plasma homocysteine level [33] Methionine synthase (MS) also known as 5-methylTHF...
Ngày tải lên: 09/09/2015, 11:28
New radial basis function network based techniques for holistic recognition of facial expressions
... Confusion matrix for first level of classification 134 6.6b Confusion matrix for second level of classification of Category A 134 6.6c Confusion matrix for second level of classification of Category ... firm basis for the same task 2.3 Model-Based Methods While motion-based techniques use dynamics of facial muscles as the main source of feature extraction, model-based techniques in contrast use ... best recognition rates for the new system as 60% for Disgust, 80% for Anger, 100% for Happiness and 90% for Surprise, Fear and Sad expressions The overall recognition rate was recorded as 85%...
Ngày tải lên: 16/09/2015, 17:11
Accounting for the origin of the arrow of time spontaneous inflation or toral topology
... following the rest of the thesis if they skip this section The theory of inflation, which forms the basis of Carroll and Chen’s as well as McInnes’ theory in accounting for the arrow of time, will ... 4.3 Inability of inflation to fully account for the origin of the arrow of time 45 Possible Approaches to Accounting for the Origin of the Arrow of Time 47 5.1 Dynamical space of states ... required for inflation to take place appears to be highly unnatural as well 38 4.1 Basic theory of inflation In the basic theory of inflation, the inflation of the universe is assumed, for simplicity,...
Ngày tải lên: 26/09/2015, 10:51
Báo cáo lâm nghiệp: "New insights in the recognition of the European ash species Fraxinus excelsior L. and Fraxinus angustifolia Vahl as useful tools for forest management" pdf
... (see [9] for F excelsior) This can be useful for studies of hybridization in zones of sympatry and/or of putative replacement of common ash by narrowleaved ash, for example in the context of global ... was observed only for seeds of F angustifolia (for all progeny arrays) and St-Dyé and Tavaux seed lots Moreover, the mean germination rate was two-fold higher for F angustifolia seeds than for ... number of individuals per population: 25.4) from three areas of sympatry between these two species (Tab II) A bi-marker phenotype was assigned to each individual (0 for the absence and for the...
Ngày tải lên: 07/08/2014, 16:20
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... release of drug was studied also in plasma and in PBS after addition of glutaraldehyde Pravastatin assay by UPLC A reversed phase UPLC method was developed and used throughout the study for pravastatin ... fragility was studied for each drug concentration In vitro releasing study The release of pravastatin as well as hemoglobin from carrier erythrocytes were determined as following, ml of packed ... inhibition of Pgp [3] Unfortunately these strategies are frequently associated with increase the risk of side effects of the statins [3,7].Therefore the developments of novel pharmaceutical formulations...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... used to determine the amount of ATP in mg of protein measured from the number of cells per well After 24 h, the microtiter plate was taken for scintillation counting of radioactive [14C]AMG using ... emission was recorded at 460 and 580 nm After a 20 sec baseline reading, 0.1 ml of PBS containing 10 µM of the compound investigated was added, and the fluorescence signal was recorder for 40 sec ... significance was assumed at p level
Ngày tải lên: 26/10/2012, 10:04
Evaluation of Dredged Sediment as a Silt and Clay Source for Artificial Tidal Flats
... poly-aluminum chloride (PAC) as well as waste steel slag (WSS) (E5) A natural tidal flat (C3) at the same tidal level was chosen as a reference for monitoring benthic communities as well as physicochemical ... affects the emerging tidal flat ecosystems This research was carried out to assess the feasibility of using DS as the additive for construction of artificial tidal flats Artificial tidal flats were ... range of values observed in the five artificial tidal flats (E1―E5) of the seashore experiment Mountain sand (MS) was used because of its importance as the alternative to sea sand which is of limited...
Ngày tải lên: 05/09/2013, 09:38
Assessment of pretreatments and enzymatic hydrolysis of wheat straw as a sugar source for bioprocess industry
... biomass for production of electricity rather than using it as a feedstock for production of biofuels would lead to its greatest utilization as an energy source [48] However, the high content of ... accounts for lack of toxicity of the resultant liquor, and seems to be a feasible way of utilizing lignin as a source of these chemicals The optimum pH for delignification is 11.5 and the loading of ... milling was studied for larger screen size (12.7-50.8 mm), and optimum total specific energy consumption for wheat straw was 37.9 MJ/Mg for screen size of 25.4 mm Hammer milling was studied for smaller...
Ngày tải lên: 05/09/2013, 15:28
A STUDY ON THE USE OF CLASSROOM DISCIPLINE AS MOTIVATION FOR SECOND LANGUAGE ACQUISITION IN THE CONTEXT OF ENGLISH LANGUAGE TEAC
... of discipline as a synthesis presence of a number of complementary factors She also emphasizes the equal importance among the factors as well as pictures the general look of a disciplined classroom ... occurs as a result of conscious study of the formal properties of the language In performance, “acquired” knowledge serves as the major source for initiating both the comprehension and production of ... seen as an important aspect of SLA, because language is one of the most observable expressions of culture and because in second (as opposed to foreign) language settings the acquisition of a...
Ngày tải lên: 07/09/2013, 13:06
Designing listening tasks using authentic materials on websites as supplementary materials for the teaching of listening skills
... work 4.2 Samples of listening tasks using online materials The writer has designed some sample tasks with the requirements of skill-based or topic-based For samples of listening tasks using online ... exercises based on passages of discourse Extended response Tasks of this kind are on the whole more demanding than those of other kinds Listening serves as basis and starting point for other activities ... also “the least understood aspect of language of foreign language learning” (Belasco, 1964, quoted from http://www.melta.org.my) There is no fixed set of criteria for different types of listening...
Ngày tải lên: 07/09/2013, 13:37
The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products
... effective tool for the control of stored-product insect pests In view of the scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain protection has increased and ... rates of sorption of homologous series of ITCs on wheat, we could show that the rate of sorption decreases with increasing molecular weight (Shaaya and Desmarchelier, 1995) In the case of methyl ... was less effective than CH3 I and needed a concentration of 6–9 μL·L−1 air for day to achieve total mortality of all the test insects except for Trogoderma larvae In the case of CS2 , adults of...
Ngày tải lên: 25/10/2013, 05:20
Accounting for new organisational forms the case of subcontracting and outsourcing
... literature, a number of areas of concern were identified as being central to the role of management accounting in the context of supply chain relations and, therefore, worthy of investigation in ... and revision of outsourcing contracts? What was the impact of accounting calculations in determining the length of the contract, and what was the role of management accounting in enforcing outsourcing ... to the LAs (IMPACTG = 3.59, IMPACT P = 3.48) 29 30 Accounting for new organisational forms Analysis of questionnaire results The NHS and LAs were given a number of additional areas to assess,...
Ngày tải lên: 27/01/2014, 10:49
Tài liệu Reporting Corrections of Errors and Changes in Accounting Principles - Amending SFFAS No. 7, Accounting for Revenue and Other Financing Sources pdf
... FEDERAL ACCOUNTING STANDARDS ADVISORY BOARD The Federal Accounting Standards Advisory Board (FASAB or “the Board”) was established by the Secretary of the Treasury, the Director of the Office of Management ... Statement of Federal Financial Accounting Standards Additional background information is available from the FASAB: • “Memorandum of Understanding among the General Accounting Office, the Department of ... (202) 512-7366 FASAB FASAB Federal Accounting Standards Advisory Board U.S General Accounting Office 441 G Street, NW, Suite 6814 (6K17V) Washington, DC 20548 Official Business Penalty for Private...
Ngày tải lên: 17/02/2014, 10:20
Tài liệu Báo cáo khoa học: Structural bases for recognition of Anp32⁄LANP proteins doc
... understanding of how interactions could take place in different regions of the molecule As part of a long-term function-oriented structural effort aimed at understanding the molecular bases of polyQ disease ... 222-232 of PP2AC protrudes out enough to fit well into the groove formed by the concave surface of the LRR domain Stabilizing interactions could form between His230 of PP2A-C and Asp119 and Asn94 of ... U2B¢¢, does not form a stable complex with the U2A¢ LRR, whereas replacement of Asp24 and Lys28 with the homologous Glu and Arg of U2B¢¢ [20] is sufficient to re-establish formation of the complex...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... amplification of Conus victoriae venom duct cDNA led to the discovery of the peptide sequence of Vc1.1 [81] detected by autoradiography As expected, formation of The synthetic peptide was not active ... and sequence comparison of these peptides implicate increasing length of the aliphatatic sidechain at position 10 (or 13 for GID) as an important determinant of selectivity for a7 vs a3b2 nAChR ... Parkinson’s disease Thus, nAChRs modulating the dopamine release gain increasing interest as drug targets, and identification of the nAChR subtypes involved is crucial for the development of pharmacological...
Ngày tải lên: 19/02/2014, 12:20