according to the principle of minimum chain of command an organization should choose the minimum number if hierarchical levels consistent with the contingencies it faces
Testing Costs and Testing Capacity According to the REACH Requirements – Results of a Survey of Independent and Corporate GLP Laboratories in the EU and Switzerland potx
Ngày tải lên :
23/03/2014, 05:22
... to use the minimum price; second, to use the mean of the minimum and the maximum price; and third, to use both of these substitutes September 2007 whereas for others only a price range or a minimum ... testing The compliance monitoring is organised at the national level The responsible national agencies report on the monitoring results to the OECD GLP Office and to the corresponding office at the ... substances The notification of new chemical substances in the EU requires specific test data to be provided by the notifier of the new substance The testing requirements depend on the volume of the...
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Báo cáo y học: " Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection" docx
Ngày tải lên :
13/08/2014, 20:22
... compared with the other underlying infections (P = 0.018 by ANOVA, Figure 2) In patients with VAP/HAP and severe sepsis/ shock, the rate of apoptosis of NK cells differed significantly compared with ... profound change of sepsis due to CAP The rate of apoptosis of NK cells and of NKT cells was more increased among patients with VAP/HAP and severe sepsis/shock than among those with VAP/HAP and ... times with PBS (pH 7.2) (Merck, Darmstadt, Germany) and subsequently incubated for 15 minutes in the dark with the monoclonal antibodies anti-CD3, anti-CD14 and anti-CD19, and the protein ANNEXIN-V...
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GUIDELINES TO THE CONSTRUCTION OF A SOCIAL ACCOUNTING MATRIX ppt
Ngày tải lên :
06/03/2014, 21:20
... transfer matrix, one then does not have to show both the remitting and the receiving institution by transaction Lack of data is only one of the complicating factors; another is an abundance of ... rather close to the SAM reference year; and (2) it must be possible to classify the raw data in accordance with the taxonomies applied in the SAM It goes without saying that SAM builders can ... into a SAM, the more inconsistencies can manifest themselves On the other hand, the time needed for constructing a SAM expands very rapidly relative to the total number of accounts Secondly, the...
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Báo cáo khoa học: Investigation of the contribution of histidine 119 to the conduction of protons through human Nox2 pptx
Ngày tải lên :
07/03/2014, 16:20
... acts as an inhibitor of the influenza A M2 proton channel and hence prevents the uncoating of the viral particle and release of its genome into the cell [18,23] Therefore, the influx of protons through ... that the Trp41 side chain blocks the pore of the channel and that the interaction between protonated His37 and Trp41 pulls the Trp41 side chain out of the pore of the channel, thereby opening the ... turns of the helix above His119 and not on the same face of the helix Therefore, the distance and the orientation of His119 to Trp125 is too great to permit a cation–p interaction similar to that...
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facile hydrothermal route to the controlled synthesis of a - fe2o3 1 - d nanostructures
Ngày tải lên :
19/03/2014, 16:48
... Foundation of Shandong Province (Nos Q2006F05, Y2005F11), the Applied Project of Yantai City (No 2005227), and the Applied Pro- Facile hydrothermal route to the controlled synthesis of α-Fe2O3 1-D nanostructures ... which means that the introduction of SnCl4 caused the formation of α-Fe2O3 instead of FeOOH We also tried to increase the addition of SnCl4 concentration to 0⋅66 mmol, and a single phase of α-Fe2O3 ... focused on the areas of large amount of nanoparticles, one can see the intense diffraction rings of polycrystals, which indicates the formation of well-crystallized product According to the index...
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Economic Report of the President 2008 (Economic Report of the President Transmitted to the Congress) potx
Ngày tải lên :
23/03/2014, 07:20
... Economic Report of the President Transmitted to the Congress February 2008 together with THE ANNUAL REPORT of the COUNCIL OF ECONOMIC ADVISERS UNITED STATES GOVERNMENT PRINTING OFFICE WASHINGTON : 2008 ... earmarks, and balance the budget by 2012 without raising taxes Second, we must trust Americans with the responsibility of homeownership and empower them to weather turbulent times in the market ... Economic Advisers herewith submits its 2008 Annual Report in accordance with the provisions of the Employment Act of 1946 as amended by the Full Employment and Balanced Growth Act of 1978 Sincerely,...
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Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency pot
Ngày tải lên :
29/03/2014, 06:21
... Board of Governors of the Federal Reserve System (2005), The Profitability of Credit Card Operations of Depository Institutions, annual report submitted to the Congress pursuant to section of the ... is, the risk of economic loss due to the failure of a borrower to repay according to the terms of his or her contract with the lender Within any given loan portfolio—that is, any group of loans ... Report to the Congress on Practices of the Consumer Credit Industry 23 the National Credit Union Administration, the Office of the Comptroller of the Currency (OCC), and the Office of Thrift Supervision...
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Báo cáo Y học: Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli pptx
Ngày tải lên :
31/03/2014, 08:20
... dissociation constant and n is the number of protons involved in titration The change in absorbance observed in the reaction of GadB-K276A and GadB-K276H mutants with glutamate was analyzed with Eqn (2) ... positioning the Ca-COO– bond orthogonal to the plane of the delocalized cofactor imine system Moreover, the release of cofactor as PLP when the enzyme was treated with NaOH after completion of ... DISCUSSION Many of the alterations produced by mutating the activesite Lys276 of GadB can be attributed to changes in the conformational properties of the protein The findings that the mutation to alanine...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part1 pdf
Ngày tải lên :
19/06/2014, 15:20
... to improve, these financial statements will prove to be an important management tool for policy-makers and the public The publication of these audited financial statements represents yet another ... Because of current data limitaof its citizens and for national defense tions, the GAO is not able to render an Yet, to this date, the U.S Government opinion on the reliability of these finanhas ... statements The Administration is statement of its finances in accordance committed to improving the reliability with applicable accounting standards of the financial information so that the This...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part2 pptx
Ngày tải lên :
19/06/2014, 15:20
... significant commitments associated with Federal insurance and loan programs These programs include bank deposit insurance, national flood insurance, federal crop insurance, and a range of other ... Treasury securities to earn interest for the trust funds The securities issued to the trust funds are guaranteed as to both principal and interest and backed by the full faith and credit of the U.S ... commitments to its citizens, including the provision of social insurance through the Social Security and Medicare programs and other commitments associated with Federal insurance and loan programs...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part3 potx
Ngày tải lên :
19/06/2014, 15:20
... in accordance with laws governing the use of budget authority and with other relevant laws and regulations, and (3) ensuring the reliability of financial statements Individual agency financial ... information to support the validity of their outstanding direct loans or to track the specific loans that they have an obligation to guarantee Until federal credit agencies correct these serious ... material noncompliance Further, the scope of our tests was limited by the inability to audit the financial statements Other instances of noncompliance, some of which are material to individual federal...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part4 ppt
Ngày tải lên :
19/06/2014, 15:20
... unauthorized acquisition, use, or disposition, (2) ensuring the execution of transactions in accordance with laws governing the use of budget authority and with other laws and regulations that ... operations An explanation of the nature of the social insurance trust funds is included in Note 16 together with information about the receipts, disbursements and assets of the major social insurance ... the following —At the Department of the Treasury, we conducted audits of IRS’s financial statements since fiscal year 1992 and conducted the initial financial statement audits of the U.S Customs...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part5 pdf
Ngày tải lên :
19/06/2014, 15:20
... financial statements have been prepared in accordance with Form and Content guidance specified by the Office of Management and Budget (OMB) and the Statements of Federal Financial Accounting Standards ... purpose subsidies to business and individuals including credit subsidies to housing; and (3) the Postal Service fund Transportation Most of these costs relate to grants to States and others for local ... Notes to the Financial Statements United States Government Notes to the Financial Statements for the year ended September 30 Note Summary of significant accounting policies C Direct loans and loan...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part6 doc
Ngày tải lên :
19/06/2014, 15:20
... source of credit and underwriter of risk In 1990, the Federal Credit Reform Act was enacted to improve the Government’s budgeting and management of credit programs The primary focus of the Act is to ... include towns, villages and other places that are not part of an urban area The majority of these loans mature in excess of 25 years and are secured by the property of the borrower Economic assistance ... to provide an accurate measure of the long-term costs of both direct loans and loan guarantees and to recognize these costs at the time when the loan is made The Direct Student Loan program,...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part7 doc
Ngày tải lên :
19/06/2014, 15:20
... behalf of the Indians The majority of stewardship land is “public domain” land — that is, large areas of territory acquired by the nation between 1781 and 1867 All areas of the nation other than the ... their management responsibility into five primary land types: (1) rangeland; (2) forest land; (3) riparian and wetlands; (4) aquatic areas and (5) other habitat and wastelands Rangeland is land ... resource; (3) to preserve a natural diversity and abundance of fauna and flora and (4) to provide and understanding and appreciation of fish and wildlife ecology, and to provide refuge visitors a safe,...
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Report to the Congress FINANCIAL AUDIT 1997 Consolidated Financial Statements of the United States Government_part8 potx
Ngày tải lên :
19/06/2014, 15:20
... traditionally separate from and independent of the other central Government organizations and functions Significant entities included in this consolidation Executive Office of the President Office ... Department of Housing and Urban Development Department of the Interior Department of Justice Department of Labor Department of State Department of the Air Force Department of the Army Department of the ... Consolidated Financial Statements of the United States Government, Fiscal 1997 65 66 Supplemental Table and Appendix A ppendix: List of significant U.S Government entities included and entities excluded...
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United States Report to the Congress FINANCIAL AUDIT Examination of Customs’Fiscal Year _part1 potx
Ngày tải lên :
20/06/2014, 06:20
... General of the United States B-252376 June 30,1993 To the Commissioner of the Customs Service In accordance with the Chief F’ inancial Officers (0) Act of 1990, the United States Customs Service ... laws and regulations during fiscal year 1992 We are sending copies of this report to the Commissioner of Customs; the Secretary of the Treasury; the Director of the Office of Management and Budget; ... compliance with laws and regulations related to the financial statements Pursuant to the Chief Financial Officers Act of 1990 (Public Law lOl-576), Customs was required to prepare agencywide financial...
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United States Report to the Congress FINANCIAL AUDIT Examination of Customs’Fiscal Year _part2 potx
Ngày tải lên :
20/06/2014, 06:20
... and given the CFOthe authority and responsibility necessary to begin to correct many of the problems identified in our audit However, the depth and number of the problems found is such that it ... current and accurate information on the status of its receivables Because of the severity of the problems that must be dealt with, it will take a substantive effort by Customs’management before it ... effective These weaknesses seriously eroded Customs’ability to safeguard, manage, and control its import revenues and operating expenditures Chief F’ inancial Officer’ s Role Management of the Customs...
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United States Report to the Congress FINANCIAL AUDIT Examination of Customs’Fiscal Year _part3 docx
Ngày tải lên :
20/06/2014, 06:20
... systems (the Automated Commercial System) We have greatly expanded the scope and intensity of efforts to improve management and internal controls within the agency Taken together, these initiatives ... CUSTOMS OVERVIEW CUSTOMS PROFILE The U.S Customs Service is formally charged with the collection and protection of the revenue and with enforcement of “more than 600 laws for 60 agencies.” Its ... authority to assessperformance and to make judgement and take action The impact of the CFO review and financial statement preparation process on Customs goes beyond the finance function Customs...
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United States Report to the Congress FINANCIAL AUDIT Examination of Customs’Fiscal Year _part4 pot
Ngày tải lên :
20/06/2014, 06:20
... foreign offices and their missions The goal is to identify and prevent trans-shipments of textiles, confirm country production capacity, and facilitate and expedite the clearance of legitimate ... accounts for 90% of the Customs entries received from the trade community Customs has also developed automated manifest systems to expedite the transmission and review of cargo manifest information ... to ensure compliance with U.S trade laws, regulations and international agreements Since its establishment in 1973, the Office of Regulatory Audit has completed more than 11,000 audits with total...
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