a view from the british isles

... physicians and other healthcare professionals who treat pain from cancer at any stage of the disease with the hope of raising awareness of the types of therapies that may be appropriate and increasing ... in particular may have under-treated pain Primary care teams supported by palliative care teams are best placed to initiate and manage cancer pain therapy, but education of patients, carers and ... The ascending pathways are the spinothalamic and parabrachial neurones • The spinothalamic neurones connect the dorsal horn via the thalamus to the cortex These give intensity and the topographic...

Ngày tải lên: 14/02/2014, 21:20

... as to win new ones “As a COO you must pay attention to what is happening in the marketplace and the impact on clients,” Ms Dolly says “At the end of the day, it’s about helping them to meet their ... their financial performance goals amid massive regulatory change.” All of this change can be daunting According to Ms Dolly, Pershing tracked more than 200 potentially actionable regulatory changes ... managers.” As always, trainees move around the firm to build expertise and professional networks, but in the end they are expected to champion new ideas and promote useful change—not just manage...

Ngày tải lên: 04/12/2015, 00:16

... showers, washing my blonde hair slowly and rhythmically, just letting the steam clear my head and the soap wash all over me It’s probably the most peaceful part of the day Then, standing at the kitchen ... straining at their leashes or running maniacally after tennis balls Dogs are always so happy Every time I see a dog I wonder why I don’t have one In fact we don’t have any pets at all They’ve all ... too small And what was with that coat anyway? It was almost summer and I was only wearing a T-shirt Everything Robert wore was, in fact, black His tight jeans with the frayed seams, his faded...

Ngày tải lên: 06/11/2012, 16:13

... Valley Authority (Farina 1991) and the U.S National Renewable Energy Laboratory (Wyman 1991) Recent work by ARKENOL in California, USA (Cuzen 1997) and APACE in New South Wales, Australia, have ... it can be converted into chemicals and materials, human population will be able to enjoy material abundance for ages to come Biomass materials are renewable Their utilization creates no net gains ... interacting concentrated sulfuric acid and cellulose, there are likely chemical reactions taking place between the acid and the substrates, which could influence the yield as well as the degradability...

Ngày tải lên: 23/10/2013, 17:20

... 5¢-GGTTGAACCATGCTCTATGTTAAAATCAATACCATCCAA-3¢ Sense strand 5¢-GGTATTGATTTTGACATAGCGCTATGTCAAAATCAATACC-3¢ Anti-sense strand 5¢-GTACAGGGTTGAACCATGCGCTATGTCAAAATCAATACC-3¢ Sense strand 5¢-GATGGTATTGATTTTGCCATAGCGCATGGTTCAACCCTG-3¢ ... 5¢-GATGGTATTGATTTTGCCATAGCGCATGGTTCAACCCTG-3¢ Anti-sense strand 5¢-CAGGGTTGAACCATGCGCTATGGCAAAATCAATACCATC-3¢ Sense strand 5¢-TATGTATGGGTTCAATTCTTTAACAATCCACCATGCCAG-3¢ Anti-sense strand 5¢-CTGGCATGGTGGATTGTTAAAGAATTGAACCCATACATA-3¢ ... 5¢-GATGGTATTGATTTTGCCATAGAGCATGGTTCA-3¢ Anti-sense strand 5¢-TGAACCATGCTCTATGGCAAAATCAATACCATC-3¢ Sense strand 5¢-TTGGATGGTATTGATTTTAACATAGAGCATGGTTCAACC-3¢ Anti-sense strand 5¢-GGTTGAACCATGCTCTATGTTAAAATCAATACCATCCAA-3¢...

Ngày tải lên: 22/02/2014, 04:20

... n .a n .a n .a a a a a a a n .a n .a n .a n .a 40.8/31.4 b n .a 72.3/65.0 b n .a 19.6/10.6 b n .a n .a n .a n .a n .a n .a a a a a a a Marital status (% distribution) Men currently married widowed other Women ... Village # HHs Chamkaar Mon Chamkaar Mon Chamkaar Mon Doun Penh Doun Penh Prampir Meakkakra Prampir Meakkakra Tuol Kouk Tuol Kouk Daangkao Daangkao Mean Chey Mean Chey Ruessei Kaev Ruessei Kaev ... Preaek Aeng S’ang Preaek Ambel Traevy Slaa Prey Veaeng Peam Ro1 Peam Ro Prey Kandieng Battambang Battambang Ta Pung Village Sach Sou Sambour Meas Kha Sdau Anglong Kokir Tuol Chambak Roung Kou...

Ngày tải lên: 05/03/2014, 18:20

... Central Bank aimed at maintaining real interest rate stability and a competitive exchange rate rather than more traditional goals such as price stability (Figure 2).4 Özatay (1997) analyses the ... financial data in particular change in the foreign exchange rate and interest rate which are available at a high frequency and set in their anticipation of future inflation In the framework of the ... inflation rate The policy aimed at a smooth pattern in the real value for the exchange basket was named as the “real exchange rate rule”.17 ollowing a price targeting strategy, that is the real exchange...

Ngày tải lên: 06/03/2014, 14:20

... min; then a final extension at 72 °C for 10 The primers for lac1 PLAC1F (5¢-AGCTTT CATTCCCAGTGATTG-3¢) and PLAC1R (5¢-AACGAG CTCAAGTACAAATGACT-3¢) were designed according to our cloned cDNA (GenBank ... giving a calculated molecular mass of 53 212 Da Two putative polyadenylation signals (TATAAA and CATAAA) were identified near the 3¢-end, suggesting possible differential splicing over the 3¢-untranslated ... colour and the spectral maxima near 600 nm that characterize all the blue oxidases Furthermore, guaiacol is a poor substrate for the enzyme In both cases, lac1 resembles the ÔwhiteÕ laccase (POXA1),...

Ngày tải lên: 07/03/2014, 15:20

... life; as a class, they assemble data about the population as a whole Students examine the data the class assembles and draw a set of important generalizations about cancer from them These generalizations ... of preven  tion as a defense against cancer Part of the reason may be that the only data we have about factors related to cancer are drawn from whole popula  tions These data cannot tell us who ... in them as well (either the maternal or the paternal X) The observation that all the cells within a given tumor invariably have the same X chromosome inacti  vated suggests that all cells in the...

Ngày tải lên: 15/03/2014, 00:20

... by aggregation are critical steps towards understanding the mechanisms involved in the pathological aggregation of tau Tau protein purified from brain extracts or recombinant tau is able to aggregate ... was also studied Recently, Wang et al showed that AD P-tau dephosphorylated by protein phosphatase did not aggregate into filaments, whereas several protein kinases and their combinations can abnormally ... d4acetic acid buffer The pH value was adjusted by adding HCl or NaOH Sodium d4-2,2-dimethyl-2-silapentonate in a capillary tube was used as the external standard for H NMR chemical shifts Standard...

Ngày tải lên: 16/03/2014, 05:20

... degradation activity of P hilaris cellulase against crystalline cellulose, Avicel (Merck) was used under the same conditions as the CMCase assay Optimal pH for P hilaris cellulase activity against ... PCR and sequencing A QuickPrepÒ Micro mRNA Purification Kit (Amersham Bioscience) was used for isolation of mRNA from P hilaris larval midguts First-strand cDNA synthesis from the isolated mRNA and ... concentrations of these buffers The optimal pH for cellulase activity against CMC was 5.5 Although the cellulase activity was greatly reduced at pH values above 7, some activity remained at pH...

Ngày tải lên: 17/03/2014, 10:20

... through language use Grabe and Kaplan [5] also emphasize that only teachers who understand theory and make a transition from theory to practice can make the most appropriate decisions for a successful ... in an insightful manner (Bardovi-Harlig, [1]) In the examples, (1) Mary is talking to a man The man is Mary’s father, and (2) The man who Mary is talking to him is her father, we can see that ... first language Many EFL teachers in Vietnam also regard this as a vital reason when analyzing their learners’ errors Nonetheless, as Savignon [15] puts it, the analysis of learners’ errors by means...

Ngày tải lên: 22/03/2014, 10:20

... generated TMI and PR products as well as TMI data from the Naval Research Laboratory/ FNMOC for analysis of typhoons approaching Japan The Naval Research Laboratory receives email from JMA and other World ... FOR THE REPORT The audience for this report includes NASA and the Japan Aerospace Exploration Agency (JAXA), operational agencies (e.g., the National Oceanic and Atmospheric Administration [NOAA], ... INTRODUCTION The Tropical Rainfall Measuring Mission (TRMM) case exemplifies a broader challenge faced by the National Aeronautics and Space Administration (NASA) and other federal agencies that operate...

Ngày tải lên: 22/03/2014, 23:20

... particular, the mastering of collaborative technologies—and applications that channel and analyse the information gained from them—will make widespread in 2013 what a handful of companies are beginning ... such as Club China and Club Africa, users can contact each other to ask for advice and information about the countries they are travelling to They can also see who else is travelling to the same ... basis Today that isn’t possible.” Access will have to be managed at the level of each individual application, he argues, which means that internal data will have to be classiÞed as a way of determining...

Ngày tải lên: 23/03/2014, 02:20

... sericea The success of these natural products as anticancer agents led us to evaluate an additional plant, P philadelphica or more commonly known as the tomatillo, to determine its efficacy as a chemopreventive ... extracts are then fractionated using an HPLC solvent system, and all fractions are evaluated in in vitro bioassays specific to the extract Pure compounds are then isolated from active fractions and ... the absorbance of formazan was then measured at 570 nm Each treatment was performed in triplicate, and the percentage cell growth inhibition was calculated by comparison of the absorbance readings...

Ngày tải lên: 23/03/2014, 10:20

... Finnmac-Cumhail and his men The battles were many and lasted a year and a day, and at last the "monarch of the world" was completely repulsed, and driven from the shores of Ireland In the battle, ... of the drink, bathe the man in the water, and let him eat hallowed bread and cheese and garlic and cropleek, and drink a cup full of the drink; and when he hath been bathed, smear with the salve ... lunatic flogged, for he says that was in the street "It was a good plea in those days to an action for assault, battery, and false imprisonment, that the plaintiff was a lunatic, and that therefore...

Ngày tải lên: 23/03/2014, 23:20

Ngày tải lên: 12/06/2014, 11:27

... inefficacy and adverse events Variable Overall withdrawal Withdrawal due to inefficacy Withdrawal due to adverse events Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis ... with adalimumab The baseline characteristics of the PsA patient cohort and the three anti-TNF groups are presented in Table At baseline, the mean (standard deviation) age of all patients was 45.7 ... etanercept was 2.1 person-years and for adalimumab was 1.6 person-years – reflecting the time that these drugs became readily available on the market Kaplan–Meier survival analyses showing rates...

Ngày tải lên: 09/08/2014, 14:20

... Peru, Colombia, Venezuela and Puerto Rico Northern America: United States and Canada Oceania: Australia and New Zealand Asia: India, Malaysia, Philippines, Singapore, Israel, Taiwan, Thailand, Hong ... Others, Argentina, Brazil, Chile, Colombia, Latin America Others, Mexico, Peru, Australia, Oceania Others, Asia Others, India, Israel, Malaysia, Philippines, Taiwan, and Thailand LDC, Low-Dose ... overall, and for patients with and without vasopressors Continuous variables were compared across treatment groups using non-parametric analysis of variance (ANOVAs) and qualitative variables...

Ngày tải lên: 13/08/2014, 20:22

Ngày tải lên: 11/11/2014, 20:10