a viable option for stem cell graft

... pattern will make this approach therapeutically relevant Cancer stem cells Self-renewal is the hallmark of both stem cells and cancer cells, and in his talk on leukemia stem cells, Weissman addressed ... (Groupe Hospitalier Pitie-Salpetriere, Paris, France) described the successful use of skeletal muscle satellite cells as an alternative for cell- transplantation therapy for heart failure After successful ... intriguing parallel Many pathways classically associated with cancer also control stem- cell self-renewal He pointed out that stem cells continue to divide over a long period of time and, as a consequence,...

Ngày tải lên: 14/08/2014, 14:21

... environments can be used to test the tolerance of cells to mechanical and shear forces, gases, oxidants and other extracellular cues that charac­ terize the disease environment Physical, mechanical and ... single cell, for example the apical versus basal signals that will be encountered by a polarized cell In traditional mass culture, cells align in random fashion, and although matrix coatings on tissue-culture ... manual handling of hESCs is an important factor in their instability over time, and therefore automated techniques for passaging and expansion may be a method for overcoming the problem of karyotypic...

Ngày tải lên: 06/08/2014, 19:21

... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... Bronchoalveolar lavage was positive for HHV6b too and negative for Adenovirus, Influenza, Parainfluenza, Respiratory syncytial virus and Legionella pneumophilia Immediate treatment with foscarnet and ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- cell transplantation AJNR Am J Neuroradiol...

Ngày tải lên: 12/08/2014, 04:21

... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... Bronchoalveolar lavage was positive for HHV6b too and negative for Adenovirus, Influenza, Parainfluenza, Respiratory syncytial virus and Legionella pneumophilia Immediate treatment with foscarnet and ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- cell transplantation AJNR Am J Neuroradiol...

Ngày tải lên: 12/08/2014, 04:22

... needles are used • CAT Scan When an MRI is not available, a CAT Scan can be used instead It uses X-rays to make a computerized picture of the brain and check for bleeding • Transcranial Doppler ... his pain The second part states what the teen will for himself to manage the pain See Appendix K for a sample Pain Management Agreement NOTE: If a teen has a fever with pain or if the pain is ... Also, thanks to the Genetic Disease Branch, California Department of Health Services staff for their assistance, particularly Karen Whitney, MS, Genetic Disease Program Specialist, Kathleen Velazquez,...

Ngày tải lên: 12/02/2014, 12:20

... Glycan and glycosaminoglycan binding properties of stromal cell- derived factor (SDF) -1alpha Glycobiology 10, 21– 29 34 Valenzuela-Fernandez A, Palanche T, Amara A, Magerus A, Altmeyer R, Delaunay ... ligand for LESTR ⁄ fusin and prevents infection by T -cell- line-adapted HIV-1 Nature 382, 833–835 1950 N Charnaux et al Pablos JL, Amara A, Bouloc A, Santiago B, Caruz A, Galindo M, Delaunay T, ... immunofluorescence A a b c B Fig PGs on HeLa cells (A) Cell surface expression of SD-1, SD-4 and CD44 on HeLa cells HeLa cells (5 · 105) were stained for FACS analysis with anti-(SD-1) DL-101 mAb (a) , anti-(SD-4)...

Ngày tải lên: 16/03/2014, 18:20

... platyhelminths and acoels are particularly attractive invertebrate models for stem- cell research They present a number of advantages, including the fact that a large pool of stem cells is available throughout ... Sánchez Alvarado A: Cell turnover and adult tissue homeostasis: From humans to planarians Annu Rev Genet 2007, 41:83-105 Reddien PW, Sánchez Alvarado A: Fundamentals of planarian regeneration Annu ... et al demonstrates that in acoels irradiation dramatically reduces cell proliferation, abolishes the expression of a stem cell marker, and ultimately leads to death [4], indicating that neoblasts...

Ngày tải lên: 06/08/2014, 19:21

... prognosis Page 11 Autologous BMT for MDS is not an option for this patient population E Severe aplastic anemia (SAA) and Fanconi's anemia (FA) 1, Allogeneic marrow transplantation is the treatment ... Deborah Branney Davison Ambulatory management following bone marrow transplant (BMT) 411 411 Page i A Clinical Guide to Stem Cell and Bone Marrow Transplantation Page Introduction to Stem Cell and ... marrow—Transplantation—Handbooks, manuals, etc Hematopoietic stem cells—Transplantation—Handbooks, manuals, etc I Davison, Deborah Branney II Rust, Deborah M III Title [DNLM: Stem Cells—transplantation—handbooks...

Ngày tải lên: 10/08/2014, 08:20

... etoposide Hypocalcemia Carboplatin, cisplatin Hypokalemia Carboplatin, cisplatin Hypomagnesemia Carboplatin, cisplatin Hyphonatremia Carboplatin, cisplatin Hypophosphatemia Carboplatin, cisplatin, cyclophosphamide ... and fractionated total body irradiation as a preparatory regimen for marrow transplantation in patients with advanced hematological malignancies: a phase I study Bone Marrow Transplant 1992;10:83–88 ... bone marrow transplantation Bone Marrow Transplant 1991;8:159–170 Thrombocytopenia Adams JA, Gordon AA, Jiang YZ, MacDonald D Thrombocytopenia after bone marrow transplantation for leukemia; changes...

Ngày tải lên: 10/08/2014, 08:20

... glabrata and Candidida krusei Lacks fungicidal activity against Aspergillus species, Generally given IV early post-transplant and continued for 30 to 40 days in autologous or PBSC transplant patients ... Mickelson EM, Hansen JA HLA-matching in marrow transplantation Marrow Transplant Rev 1991;1:8–13 19 Vogelsang GV Acute graft versus host disease following marrow transplantation Marrow Transplant Rev ... in allogeneic transplantation for patients with a variety of disorders (e.g., malignancy, immunodeficiency disease, Fanconi's anemia) Advantages and disadvantages of umbilical cord blood transplantation...

Ngày tải lên: 10/08/2014, 08:20

... sinopulmonary Gram negatives (E Coli, P aeruginosa, Klebsiella) Gastrointestinal, blood, oral, perirectal Fungal: Candida species (C albican, glabratta krusei) Oral, esophageal, skin Aspergillus (fumagata, ... immunofluorescent antibody, or rapid shell, silver stain, acid-fast bacteria, Mycoplasma, and Legionella e) Gastrointestinal: stool for CMV antigen and culture Stool should always be sent for ova and parasites ... elevated related to renal hypoperfusion f) Electrolytes: variable abnormalities g) Chest x-ray: Rule out capillary leak or ARDS Management a) Remove CVAD as soon as feasible, and provide alternative...

Ngày tải lên: 10/08/2014, 08:20

... pulmonary edema and capillary leakage Page 201 g) Radiation-induced pulmonary damage is the major cause of BMT-related pulmonary damage The degree of damage is related to the amount of radiation ... transplant b) HLA-mismatched donor transplant c) Sex-matched transplant, with a female-to-male graft having increased incidence, especially with female donors who are multiparous or have had a ... decreased voltage (see Figure 5.7 on p 208 for the normal cardiac axis) h) Symptoms may progress to hemorrhagic myocarditis, cardiac tamponade, and death Radiation-induced cardiac damage a) Dyspnea...

Ngày tải lên: 10/08/2014, 08:20

... different angles The x-ray is directed at and moves around the stationary body part Application: Can be used to image intracranial disease, abdominal and chest disease, and bowel disease Procedure ... P, Barra A, Intrator L, et al Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation Blood 1987;70:779–785 Barnes HV Pleural ... children after bone marrow transplant for hematological malignancies Bone Marrow Transplant 1991;8(suppl 1)2–4 Savdie E Renal complications In: Atkinson K, ed Clinical Bone Marrow Transplantation Cambridge,...

Ngày tải lên: 10/08/2014, 08:20

... IV Acute systemic candidal infections: 400 mg load, then 200 mg/d IV Other SE: H /A, nausea, rash, abdominal pain, e levels of ALT, alanine Transaminase (ALT), an alkaline phosphatase Don not administer ... SE: anorexia, N/V, sinus bradyca AV block, sinoatrial block, atrial nodal arrhythmias, bigeminy, trig atrial tachycardia, H /A, fatigue, lethargy, neuralgia, vertigo, disorientation, hyperkalemia ... mEq/mL at a dose of mEq/kg IVP; may repeat Use of IV NaHCO3 should be reserved for docu metabolic acidosis and for hyperkalemia-induce cardiac arrest SE: Metabolic alkalosis, hyperna hypokalemia,...

Ngày tải lên: 10/08/2014, 08:20

... A AB Major A, O A, AB B O Minor O B,AB B A Major O B,AB B AB Major B,O B,AB O A Major O A, AB O B Major O AB O AB Major O AB AB O Minor O AB AB A Minor A, O AB AB B Minor B,O AB Recipient type Page ... years 13.8 ± year Breast development: females Prepubertal Breast buds appears; areolae enlarge 11.2 ± 1.1 years Elevation of breast contour; areolae enlarge 12.2 ± 1.1 years Areolae and papilla ... such as carbamazepine, clonazepam, and valproic acid, are useful in management of lancinating or "stabbing" neuropathy H Herpes zoster is a common complication in the post-transplant setting Management...

Ngày tải lên: 10/08/2014, 08:20

... indicated Others view use of excessive pain medication as an abuse of the teampatient relationship and as potentially hazardous to the patient C Because each case differs, and patient pain complaints ... Psychological issues in bone marrow transplantation Pediatrics 1977;60:625–631 Page 439 13 Farkas Patenaude A, Rappeport J Collaboration between hematologists and mental health professionals on a bone ... bacterial contamination, marrow aspiration and, 114 Albumin (human), 365t Alloantibodies, platelet, 386 Allogeneic bone marrow, 113-15 Allopurinol, 364t Amikacin sulfate, 292t Aminocaproic acid,...

Ngày tải lên: 10/08/2014, 08:20

... fossa Another relevant factor is that the navel’s skin, naturally already through the abdominal wall, facilitates the anastomosis with the continent conduit, making the patient’s abdomen more aesthetically ... surgical option for bladder augmentation with a continent stoma: a case report Journal of Medical Case Reports 2011 5:49 Submit your next manuscript to BioMed Central and take full advantage of: ... ileocystoplasty and, for patients unable or not adapted to intermittent catheterization, Mitrofanoff’s principle (in which the vascularized ileocecal appendix is anastomosed at the skin and bladder,...

Ngày tải lên: 11/08/2014, 00:22

... in cases In the latter, pathological tumor stage was T 1a in 25 cases, T1b in cases and larger T2 in cases Histological data and nuclear grade was available In the A method, 84.3% had clear cell ... skin incision Page of 13 Tanaka M, Tokuda N, Koga H, Yokomizo A, Sakamoto N, Naito S: Hand assisted laparoscopic radical nephrectomy for renal carcinoma using a new abdominal wall sealing device ... T1N0M0 renal cell carcinoma That’s because we thought that laparoscopic approach caused peritoneal adhesion more than retroperitoneoscopic approach In T2-T3aN0M0 renal cell carcinoma as well as in...

Ngày tải lên: 11/08/2014, 07:21

... treatment of rheumatoid arthritis but not for OA due to its limited and short-term effectiveness Maintaining a balance in levels of IL-1β might be important as a treatment approach for OA, and agents ... research grant (RG3891 to CR) Author details Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA 2Birmingham VA Medical Center, Birmingham, AL 35294, USA 3Division ... the targets of GTPs in general, and of EGCG in particular, in arthritic/OA animal models The use of GTPs may be better than EGCG as GTPs may have synergistic effects, are more stable and are easily...

Ngày tải lên: 12/08/2014, 17:22

... significant bone marrow involvement For example, the large amount of tumor material typically available from leukemia patients makes these cells accessible for autologous patient-derived vaccine ... used for nuclear DNA isolation Prior to DNA isolation, nuclei were washed in PBS and incubated with 0.5U DNase I (Ambion, Austin, TX) at 37° for 10 and washed again twice in PBS Nuclear DNA was ... 106 cells and the black bars represent neo amplification from non-nucleofected U2OS cells Nuclear DNA was harvested and amplified from separate samples, error bars indicate the standard deviation...

Ngày tải lên: 14/08/2014, 19:22