a target for the prevention of fibrosis

... detail of 5-year age bands, the analysis of a single age group resulted in nearly identical ICERs as that of the 5-year age group it falls within For example, if a vaccination strategy was applied ... underestimated The underestimation of costs does have the advantage that it does not favour the vaccine arm and therefore represents a conservative approach A sensitivity analysis which varied all health ... i.e an 8% increase and a 12% decrease respectively In addition, the base case assumes that the efficacy of the vaccine is constant over the lifetime of the population, therefore an assumption of...

Ngày tải lên: 13/08/2014, 11:22

... a common forum for action the European Platform for Action on Diet, Physical Activity and Health was launched in March 2005 The Platform brings together all relevant players active at European ... diseases” I STATE OF PLAY AT EUROPEAN LEVEL I.1 Unhealthy diets and lack of physical activity are the leading causes of avoidable illness and premature death in Europe, and the rising prevalence ... national, regional or local level, and to cooperate with similar fora at national level At the same time, the Platform can create input for integrating the responses to the obesity challenge into a...

Ngày tải lên: 14/02/2014, 13:20

... type diabetes subjects Immunogenetics 2010, 62:101-107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association ... and state of activation, may not accurately reflect the status and behavior of their counterparts localized in the target organ In this latter regard, there is experimental evidence that the blood ... Health Center, 1650 Cedar Avenue, Montreal, H3G 1A4 , Qc, Canada Full list of author information is available at the end of the article thymic and peripheral CD4+ T cells in humans and mice, and...

Ngày tải lên: 18/06/2014, 16:20

... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the ... studies vary, they all used actual primary clinical data from trials and applied them to an economic model These data may however not always be generalised outside the controlled environment of the...

Ngày tải lên: 09/08/2014, 01:22

... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the ... studies vary, they all used actual primary clinical data from trials and applied them to an economic model These data may however not always be generalised outside the controlled environment of the...

Ngày tải lên: 09/08/2014, 13:22

... that these clinics may not be representative of other rural areas in the district Additionally, the survey was based at the health facility and therefore only mothers seeking antenatal care at ... widowed The number of women pregnant for the first time (prime gravida) was the same in the rural and urban areas Radio ownership was high in both rural and urban areas but higher in urban areas Table ... were administered to mothers attending antenatal clinics in rural and urban parts of Mbarara, a district in southwestern Uganda The PMTCT program in Mbarara district started in August 2002 at Mbarara...

Ngày tải lên: 10/08/2014, 05:20

... planned and performed the operation TGV interpreted the CT angiography and gave specific information about the vascular anatomy of the pelvic kidney All authors read and approved the final manuscript ... tomography angiography of a 59-year-old patient revealed an asymptomatic abdominal aortic aneurysm, and a solitary pelvic kidney, and the composition of the renal vasculature One renal artery ... literature describing the management of CSPK with AAA Kaplan et al first presented a patient with a single renal artery arising from the right common iliac artery [7] The AAA was successfully repaired...

Ngày tải lên: 11/08/2014, 00:22

... models and may enable targeting of modifiable causes of non-response The E-couch program has been developed on a platform that is immediately scalable, thus making it a practical prevention program ... Biology and Environment, Australian National Page of University, Australia 2ORYGEN Research Centre, University of Melbourne, Australia 3Centre for National Research on Disability and Rehabilitation ... prevention trial and Research Assistant to Professor Christensen PJB Expertise in statistical analysis and data management of large-scale behavioural research studies, and experience in the design and...

Ngày tải lên: 11/08/2014, 16:22

... Statistical analysis Continuous demographic variables were analysed using two-way analysis of variance (ANOVA) and categorical demographic variables by a Cochran-Mantel-Haenszel test A p-value ... p-value of < 0.05 was considered significant Further information on statistical analysis is given in the Additional file 4: Statistical analysis The primary efficacy variable was the number of exacerbations ... Pierre Arvis, Bayer Schering Pharma, medical expert; Julie Russell, Bayer Schering Pharma, lead statistician; Barbara Hampel, Bayer Schering Pharma, clinical lead; and Jeff Alder, Bayer HealthCare,...

Ngày tải lên: 12/08/2014, 11:20

... performing a meta-analysis of comparative trials studying the effect of the administration of antibiotics via the respiratory tract on the colonization of the respiratory tract by bacteria and development ... language were allowed to be included in our meta-analysis Data extraction The data extracted from the articles for further analysis were the study population, the dosage and the duration of the administered ... Clin Trials 1986, 7:177-188 Mantel N, Mocarelli P, Marocchi A, Brambilla P, Baretta R: Stratified analysis of multivariate clinical data: application of a Mantel-Haenszel approach Stat Med 1983,...

Ngày tải lên: 13/08/2014, 03:20

... treatment with APC was started before the initiation of injurious ventilation Therefore, it remains unknown at present whether inhaled APC would be beneficial if initiated after the lungs have ... whether inhaled APC can prevent or minimize primary or secondary lung damage when low tidal volumes are used for mechanical ventilation Abbreviations APC, activated protein C; ERK, extracellular-regulated ... exposed to large tidal volumes, an important clinical issue Additionally, low-tidal-volume ventilation has become the standard of care in critically ill patients because of studies showing that its...

Ngày tải lên: 13/08/2014, 20:21

... cultural and local adaptation In the months after the central training, all intervention centres planned the adoption of the intervention by the local stakeholders Plans for cultural and local adaptations ... where an existing platform was already available The establishment of the community platform and the school working groups enabled adaptation to the local culture and circumstances and ensured the ... cultural adaptation The primary aim of integrating opportunities for cultural adaptation was to implement a culturally equivalent version of the overall intervention framework in all participating...

Ngày tải lên: 14/08/2014, 08:20

... overview of a patient's asthma control with a quick glance Patients assume active role in their health care Implementation: The Asthma Task Force developed an Asthma Test, Asthma Management Plan, and ... 1) In Navajo asthma patients, perceptions of asthma and beliefs about the activity of asthma medications influence when and how often asthma medicines are taken, as well as the use of health services ... within the health centers The Asthma Task Force developed medical record documents to facilitate superior asthma care (including an Asthma Test, Asthma Management Plan, and Asthma Action Plan),...

Ngày tải lên: 14/02/2014, 13:20

... former case, there is the advantage of studying reactions to real art and the disadvantage that any two works of art differ from each other in several different respects, so that the actual factor ... et al., 2006) Another major difference among the three studies is the task that participants were asked to perform Kawabata and Zeki (2004) asked their participants to rate the beauty of the ... preference have been captured by two of the reviewed studies: the representation of reward value and the awareness of the emotional state The cortical processing of the magnitude of the reward of the...

Ngày tải lên: 19/02/2014, 17:20

... framework, QARLA, that addresses such issues Given a set of manual summaries and another set of baseline summaries per task, together with a set of similarity metrics, QARLA provides quantitative measures ... estimates the quality of an automatic summary a ∈ A, given a set of models M and a similarity metric x An obvious first attempt would be to compute the average similarity of a to all model summaries ... compare the summary with the models in M With Q, we can compare the quality of automatic summaries • A measure KM ,A (X) ∈ [0, 1] that estimates the suitability of a set of similarity metrics X for...

Ngày tải lên: 17/03/2014, 05:20

Ngày tải lên: 19/03/2014, 00:20

... The application of disinfectants via a foamer allows for better visualization of where product has been applied and also prolongs the contact between the chemicals and the surfaces.  Application of disinfectants via a foamer enhances their effectiveness ... The same process occurs when entering the chamber from the inside of the building via the internal door.  An external view of the double door chamber  v  The chamber must also contain an exhaust fan designed to clear all the air in  ... or an animal air space within the facility.  Once animals/personnel have entered and both doors are closed, the fan is  turned on and allowed to run for the designated time period.  A view of the exhaust fan within the chamber...

Ngày tải lên: 22/03/2014, 12:20

... GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTAATTTTATGCTGACTCAGCCCCA CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAGGAGACGGTGACCAGGGTGCC CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAAGAGACGGTGACCATTGTCCC CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAGGAGACGGTGACCAGGGTTCC ... GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGACATCGTGATGACCCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGAAACGACACTCACGCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGAAATTGTGCTGACTCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTCAGCTCGTGTTGACGCAGCCGCC ... GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGACATCCAGATGACCCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGATGTTGTGATGACTCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGAAATTGTGTTGACGCAGTCTCC GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGACATCGTGATGACCCAGTCTCC...

Ngày tải lên: 23/03/2014, 13:20

... often the case that a grammar assigns just one of a range of logically equivalent representations to a sentence; designers of grammars for use in analysis generally take care to ensure that the ... translation application Similarly, the transfer rules of Zajac (1990) express a relation between subparts of a single complex structure Such an approach does not appear suitable for the appl/cation ... from the source representation to a target representation, and from this to an expression in the target language The first and last of these are to be performed by parsing and generation with natural...

Ngày tải lên: 01/04/2014, 00:20