... computing and information science From core foundational and theoretical material to final-year topics and applications, UTiCS books take a fresh, concise, and modern approach and are ideal for self-study ... logical operators are && for AND and for OR Thus for boolean variables a and b, the boolean expression a& &b; is evaluated to true if and only if both a and b are true The following program presents ... Monniaux, Giacomo Nannicini, Sylvain Pradalier, e St´phane Redon Maria Naya Plasencia, Andrea Roeck, David Savourey, and e Olivier Serre This book became possible thanks to the warm encouragement...
Ngày tải lên: 29/06/2014, 08:20
... with matrices, it is very easy to create vector and matrix variables, and there are many operations and functions that can be used on vectors and matrices A vector in MATLAB is equivalent to what ... many operators and built-in functions that can be used in interactive expressions 1.1 GETTING INTO MATLAB MATLAB is a mathematical and graphical software package with numerical, graphical, and ... inclusive range from 50 to 100 21 Get into a new Command Window and type rand to get a random real number Make a note of the number Then exit MATLAB and repeat this, again making a note of the random...
Ngày tải lên: 23/03/2014, 15:53
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 2 pptx
... substance that can act as an electron pair acceptor, and a L ewis base is any substance that can act as an electron pair donor In many enzymatic reactions, protons are transferred from one chemical ... Potential energy diagram for the van der Waals attraction between two helium atoms [Data adapted from Gray (1973) and fit to Equation 2.14.] by a critical distance known as the van der Waals contact ... lysine, and arginine, and aspartic and glutamic acids The ability of these side chains to participate in acid—base chemistry provides enzymes with a mechanism for proton transfer to and from reactant...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 3 pot
... ligand at the initiation of the experiment) The chambers are then sealed, and the apparatus is place on an orbital rocker, or a mechanical rotator, in a thermostated container (e.g., an incubator ... nonequivalent ligand binding sites The data and fit to Equation 4.27 are the same as for Figure 4.5 in all fields put a great deal of emphasis on finding mathematical transformations of data that would ... such as Amicon and Millipore) Here the receptor and ligand are again allowed to reach equilibrium in an appropriate buffer solution, and the sample is loaded into the top of the centrifugation...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 4 ppsx
... noncovalently associated as a multiprotein complex This supercomplex, referred to as CAD, comprises the enzymes carbamyl phosphate synthase, aspartate transcarbamylase, and dihydroorotase Because the active ... diffusion barrier to rapid catalysis 5.6 EXPERIMENTAL MEASUREMENT OF kcat AND Km 5.6.1 Graphical Determinations from Untransformed Data The kinetic constants V and K are determined graphically with ... common to perform initial experiments with a limited number of data points that span as broad a range of substrate concentrations as possible (at least a 100-fold substrate concentration range) to...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 5 docx
... by acting as Brønsted—Lowry acids and bases in what is referred to as general acid and general base catalysis For catalysis by small molecules (nonenzymatic reactions), general acid/ base catalysis ... TRANSITION STATE STABILIZATION 165 Table 6.2 Some examples of electrophilic catalysis in enzymatic reactions Enzyme Acetoacetate decarboxylase Aldolase Aspartate aminotransferase Carbonic anhydrase ... enzyme state Again, the initial and final states are energetically identical in the catalyzed and uncatalyzed reactions However, the overall activation energy barrier has been substantially reduced...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 6 pot
... noise and having a reasonable signal to Figure 7.10 Deviation from Beer’s law Over a small concentration range, the absorption at some analytical wavelength tracks linearly with analyte concentration, ... sulfate standard at 453 nm, when the same fluorometer is used to excite both sample and standard, at the same wavelength Of course, both sample and standard measurements must be made under the same ... recommended names, alternative names, catalytic activities, information on cofactor utilization, and associated diseases for a very large collection of enzymes A complete description of the data bank and...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 7 pdf
... Protein Analysis: A Practical Guide to L aboratory Protocols, Chapman & Hall, New York Copeland, R A. , Williams, J M., Giannaras, J., Nurnberg, S., Covington, M., Pinto, D., Pick, S., and Trzaskos, ... tedious task and undertaking it often is impractical Instead, if the assays are to be run at elevated temperatures (e.g., 37°C), the pH meter should be calibrated at the assay temperature and all ... commonly used alternative methods are available to quantify peaks from strip-chart recordings The first is to measure the peak height rather than integrated area as a measure of analyte mass This is...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 8 docx
... reaction as a function of substrate concentration at 0, 10, and 25 M concentrations of an inhibitor, and obtain the results shown in Table 8.1 If we were to plot these data, and fit them to Equation ... quantitative structure—activity relationships (QSAR) was first championed by Hansch and his coworkers (Hansch, 1969; Hansch and Leo, 1979) In a typical QSAR study, a series of analogues of a lead ... particular enzymatic reaction With a lead compound in hand, analysts subject the substance to small structural perturbations and test these analogues for inhibitor potency This most basic form of SAR...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 9 ppt
... 2695 Cha, S., Agarwal, R P., and Parks, R E., Jr (1975) Biochem Pharmacol 24, 2187 Copeland, R A (1994) Methods of Protein Analysis, A Practical Guide to L aboratory Protocols, Chapman & Hall, ... (1970) and Anderton and Rabin (1970) for examples of this approach 10.5.3.3 Affinity Labels Covalent modifying groups can often be incorporated into substrate analogues and other ligands (cofactors, ... carbon of the substrate and an active site serine residue as the attacking nucleophile Several groups have taken advantage of the ability of boron to adopt a tetrahedral ligand sphere in preparing...
Ngày tải lên: 13/08/2014, 07:20
A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 10 doc
... inhibitor of threonine deaminase Another classic example of feedback inhibition comes from aspartate carbamoyltransferase This enzyme catalyzes the formation of carbamoylaspartate from aspartate and ... Protein Analysis: A Practical Guide to L aboratory Protocols, Chapman & Hall, New York, pp 151—160 Copeland, R A. , Williams, J M., Giannaras, J., Nurnberg, S., Covington, M., Pinto, D., Pick, S., and ... kinetic data Reference: F W Perrella, Anal Biochem 174, 437 (1988) Graphfit A commercial package for data management and graphic display of enzyme kinetic data and other scientific data graphing...
Ngày tải lên: 13/08/2014, 07:20
MATLAB a practical introduction to programming and problem solving
... including vectors and matrices, will also be introduced 1.1 GETTING INTO MATLAB MATLAB is a mathematical and graphical software package with numerical, graphical, and programming capabilities It has built-in ... operations and functions that can be used on vectors and matrices 21 22 CHAPTER Introduction to MATLAB A vector in MATLAB is equivalent to what is called a one-dimensional array in other languages A matrix ... Workspace Window) clear clears out all variables so they no longer exist clear variablename clears out a particular variable clear variablename1 variablename2 clears out a list of variables...
Ngày tải lên: 06/02/2016, 08:23
Introducing qualitative methods series Georgia lepper categories in text and talk a practical introduction to categorization analysis SAGE publications (2000)
... Conversational Analysis: A Practical Guide Paul ten Have Using Foucault's Methods Gavin Kendall and Gary Wickham The Quality of Qualitative Evaluation Clive Seale Qualitative Evaluation Ian Shaw ... Researching Life Stories and Family Histories Robert L Miller Categories in Text and Talk: A Practical Introduction to Categorization Analysis Georgia Lepper CATEGORIES IN TEXT AND TALK A Practical ... researcher can build skills in the practice of categorization analysis, and a conceptual understanding of the method, in a systematic way The book also provides a practical introduction to the variety...
Ngày tải lên: 28/10/2016, 09:08
A Practical Introduction to OPtical Mirieralogy ppt
... grit and water on a glass or a metal surface Polishing the surface using diamond grit and an oily lubricant on a relatively hard 'paper' lap Buffing the surface using gamma alumina powder and water ... vesicles and found with zeolites -especially thomsonite and stilbite Analci me occurs as an authigenic mineral in sandstones, again associated with the zeolites laumontite and heulandite Analcime has ... granites and granite pegmatites as a primary mineral 62 Sorosilicates Epidote group a- zoisite has ac as the optic axial plane ,B-zoisite has ab as the optic axial plane All monoclinic epidotes have ac...
Ngày tải lên: 14/03/2014, 22:20
Low-Iodine Cookbook: Guidelines and Tips for the Low-Iodine Diet Used for a Short Time When Preparing To Receive Radioactive Iodine docx
... stewed tomatoes and unsalted tomato sauce, garlic, basil, and oregano to a saucepan (use a potato masher to mash up stewed tomatoes in the pan) Let simmer Brown the chopped meat and strain any fat, ... min) Add vegetables back to heat Eat plain or over salad to make a great fajita salad Or serve in corn tortillas made with only corn, lime, and water Another variation:serve with tomatoes, guacamole, ... Salads and Salad Dressings 18 Mixed Green Salad with Strawberry Dressing 18 Black Bean Salad 18 Egg Salad 18 Bavarian Potato Salad 19 Greens with Vinaigrette 19 Orzo Salad 19 Pasta and Pea Salad...
Ngày tải lên: 22/03/2014, 16:21
Module V Viruses and Worms.Introduction to VirusComputer viruses are perceived as a threat to potx
... program ti due to i l t f data in Software Attacks: • Intentionally launched malicious programs enable the attacker to use the computer in an unauthorized manner • General Categories: • Viruses and ... Create Computer Viruses Virus writers can have various reasons for creating and g spreading malware Viruses have been written as: • • • • • • • • • Research projects Pranks Vandalism To attack ... load than normal Computer's hard drive constantly runs out of free space Files have strange names which are not recognizable Programs act erratically Resources are used up easily Hardware Threats...
Ngày tải lên: 31/07/2014, 04:20
A Practical Introduction to 3D Game Development
... Yasser Jafal A Practical Introduction to 3D Game Development Download free eBooks at bookboon.com A Practical Introduction to 3D Game Development 1st edition © 2014 Yasser Jafal & bookboon.com ... Download free eBooks at bookboon.com A Practical Introduction to 3D Game Development Contents Contents About this Book Basics of Scene Construction 1.1 Basic shapes and their properties 1.2 Relations ... supportive working atmosphere within our global group and beneit from international career paths Implement sustainable ideas in close cooperation with other specialists and contribute to inluencing...
Ngày tải lên: 08/08/2016, 17:19
Tài liệu Utilizing a plug-and-play architecture to drive down architecture to drive down docx
... of installation, labor, and capital equipment costs makes it obvious that plug -and- play connectivity offers a tremendous advantage Advantage: plug -and- play The plug -and- play approach to an FTTP ... They are capable of meeting higher performance standards and manufacturing improvements that result in lower insertion and return loss Page Hardened adapters are integrated into environmentally ... drop cables are factory-connectorized assemblies with hardened connectors on each end These cables are also pre-tested and certified at the factory to meet performance requirements Each hardened...
Ngày tải lên: 17/01/2014, 11:20