a prospective study with 60 patients pdf

... in metastatic breast cancer: a prospective study in 393 patients Markus Wallwiener1,2*, Sabine Riethdorf3, Andreas Daniel Hartkopf4, Caroline Modugno1, Juliane Nees1, Dharanija Madhavan5, Martin ... USA) Data analysis and statistics Patient demographic and clinical characteristics were summarized as medians and ranges or numbers and percentages, as appropriate The numbers of missing values ... and sample collection and analysis BS, JN, DM, and SS participated in organizing or reporting the data and constructing databases, and conducted data management BS performed the statistical analysis

Ngày tải lên: 14/10/2020, 13:29

... in survival with chemotherapy, patients with metastases at diagnosis and patients who relapse still have a poor prognosis [1, 2] New therapeutic approaches are needed for those patients Angiogenesis ... blood and urinary basic fibroblast growth factor (bFGF) levels in osteosarcoma patients, both at diagnosis and during treatment Methods: Patients with localised or metastatic osteosarcoma enrolled ... Lervat7, Nadège Corradini8, Jean-Claude Gentet9, Rémy Couderc4, Aurélie Chevance10, Céline Mahier-Ait Oukhatar11, Natacha Entz-Werle12, Jean-Yves Blay13,14 and Marie-Cecile Le Deley10,15 Abstract

Ngày tải lên: 06/08/2020, 07:33

... who are candidates of a worse clinical course [7], but with the exception of patients with mutated KRAS in metastatic colorectal cancer, predictive factors are still lacking [8] Our analytical ... free survival (DFS) in a large cohort of colon cancer patients with a reasonable long follow-up Methods Patients A total of 299 patients with colon cancer that underwent surgery at the Department ... CK18 and CK19 (AS Diagnostik, Germany) or anti-EpCAM antibody BER-EP4 (Dako, Hamburg) using the Dako REAL detection system (Dako, Hamburg, Germany) Cytospins were analysed with an ACIS (automated

Ngày tải lên: 20/09/2020, 01:06

... correlation with radiation therapy-induced outcome Cholpon S Djuzenova1*, Marcus Zimmermann1, Astrid Katzer1, Vanessa Fiedler1, Luitpold V Distel2, Martin Gasser3, Anna-Maria Waaga-Gasser3, Michael ... The parameters on initial, residual and baseline DNA damage assessed by histone γ-H2AX for each individual, as well as age, sex, and grade of GI toxicity after RT are given Fig and in Additional ... been analyzed in various population-based studies using a variety of assays that assess DNA fragmentation by means of the Comet assay, micronucleus test, chromosomal aberrations, sister chromatid

Ngày tải lên: 22/09/2020, 22:38

... patient characteristics and pharmacy adherence As patients lost to follow-up may have introduced bias into the analysis, we analysed the association of individual patient characteristics with ... follow-up or with death. Associations between patient characteristics and pharmacy adherence As patients lost to follow-up may have introduced bias into the analysis, we analysed the association of ... individ- ual patient characteristics with pharmacy adherence in a sensitivity analysis, using two scenarios, a best-case and a worst-case scenario [Table 4]. In the best-case scenario, where all participants

Ngày tải lên: 10/08/2014, 05:21

... cohort participants with OA. Participant characteristics are shown in Table 1: mean age was 70.7 years, and most were female (73.2%) and Caucasian (93.0%), with low income (52.4% reported an annual ... Adult Cardiac Care Network of Ontario: Coronary artery bypass mortality rates in Ontario. A Canadian approach to quality assurance in surgery. Circulation 1996, 94:2429-33. 26. Steele LS, Glazier ... general health score, WOMAC total score and pain subscale, education, income, living arrangements, marital status, region, and race. An interaction between age and sex was also included. Interactions

Ngày tải lên: 11/08/2014, 15:22

... (median, 126 ng/L) followed by a gradual decrease (median variation days to 7, 70%) All patients had an ejection fraction >50% Early transmitral velocity/tissue Doppler mitral annular early diastolic ... BNP elevation caused by chronic cardiac abnormalities and BNP related to acute neurocardiac injury Methods All adult patients with SAH admitted to our intensive care unit were eligible Patients ... [12,13], and LV systolic and diastolic dysfunction [14] A cardiac source of BNP is also supported by a recent study demonstrating that cardiac injury and dysfunction occurring early after SAH are associated

Ngày tải lên: 13/08/2014, 16:20

... Mulago hospital, Uganda: a prospective study Rebecca Nantanda1,3*, Marianne S Ostergaard2, Grace Ndeezi3 and James K Tumwine3 Abstract Background: Little attention has been paid to asthma in ‘under-fives’ ... ‘under-fives’ in Sub-Saharan Africa In ‘under-fives’, acute asthma and pneumonia have similar clinical presentation and most children with acute respiratory symptoms are diagnosed with pneumonia according ... children with acute asthma and pneumonia and document the factors associated with prolonged hospitalization and mortality Methods: We enrolled 614 children aged to 59 months with acute respiratory

Ngày tải lên: 27/02/2020, 13:38

... women with a sister with breast cancer Sangmi Kim1*, David L Shore2, Lauren E Wilson3, Ethel I Sanniez2, Jae H Kim1, Jack A Taylor3 and Dale P Sandler3 Abstract Background: Nonsteroidal anti-inflammatory ... 15: 960 Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of drugs commonly used to treat pain, fever and inflammation [1] Based on their long-term safety and preliminary efficacy ... meta-analyses have suggested a modest reduction in breast cancer risk in relation to use of aspirin and other NSAIDs [7, 8], a randomized clinical trial of low dose aspirin [9] and recent analyses

Ngày tải lên: 22/09/2020, 23:04

... information is available at the end of the article with an advanced stage at initial diagnosis, higher grading, family history, and BRCA mutations [7-9] Additionally, TNBC patients lack the benefit ... overall survival were associated with an improvement by 100% guideline-adherent adjuvant treatment compared to non-adherence Furthermore, TNBC patients of all ages had similar outcome parameters ... routinely available targeted therapy, which explains the growing attention of both pathologists and oncologists to an easily recognizable type of breast cancer with aggressive behavior and poor therapeutic

Ngày tải lên: 05/11/2020, 05:20

... for all patients Table summarizes the demographic data of the enrolled patients Postoperative hypoxaemia in the PACU mainly occurred in patients after abdominal surgery (45 patients, 39.8%) and ... Data are described as the mean ± standard deviation or median and interquartile range, as appropriate The LUS score was described in patients without pneumothorax (N = 85) SPO2 was assessed without ... it All authors have read and approved the final manuscript Funding None Xie et al BMC Anesthesiology (2020) 20:220 Availability of data and materials The datasets generated and/or analysed during

Ngày tải lên: 13/01/2022, 00:51

... trimester and the occurrence of gestational diabetes mellitus (GDM) A prospective study with 772 female participants was conducted in China from April 2013 to August 2014 Dietary intake was assessed ... likelihood of gestational diabetes mellitus: a prospective study Wu-Qing Huang1,*, Ying  Lu1,2,*, Ming Xu1, Jing Huang1, Yi-Xiang Su3 & Cai-Xia Zhang1 This study aimed to investigate the association between ... assessed in face-to-face and telephone interviews using a 3-day food record GDM was ascertained using a standard 75 g 2 hour oral glucose tolerance test Multivariable logistic regression was used

Ngày tải lên: 24/11/2022, 17:51

... (Ground data, GIS data and satellite imagery data) • The zonation can be regarded as a tool for sustainable agricultural development in the watershed area 17 Suggestion zones for sustainable of watershed ... implementation such as rubber plantation and irrigation system were installed in the area, and than this place was changed in dynamics way of land use system • The forest area was destroyed by increasingly ... private agencies As we know, GIS and remote sensing have an important role in linkage and analysis of such data, in particular for detection, interpretation, area calculation, monitoring and

Ngày tải lên: 17/03/2014, 11:20

... ECO-TOURISM VALUE OF NATIONAL PARK: A CASE STUDY FROM THE PHILIPPINES Gladys M. Navarro 1 Eleanor D. Paca Carlo Rimas ABSTRACT National parks or generally protected areas (PAs) normally ... explanatory variables and hypotheses Variables Table 1: Explanatory... visitor valued at P9,373.32, the annual aggregate monetary recreational value of Mt Pulag National Park is estimated ... reveals the value that people place on recreational, tourism or leisure aspects of PAs. The study by Navrud and Mungatana (Navrud & Mungatana, 1994) shows that the Travel Cost (TC) and

Ngày tải lên: 25/03/2014, 20:23

... (mean 71.4 years) at p = 0.015 Instruments Socio-demographic and clinical data Information on socio-demographic data such as age, educational level, cohabitation and marital status was obtained by ... multidimensional QOL of a reasonably sized sample of female MI survivors and that of the general female population of the same age range, as well as a thorough evaluation of the clinical importance of ... statistical software R (The R Foundation for Statistical computing, Vienna, Austria) was used for bootstrap analyses (R package boot) and permutation tests All other analyses were performed with

Ngày tải lên: 20/06/2014, 16:20

... 8 -60% pts. with mediastinal metastases Table 5: Univariate and multivariate analysis of factors influencing survival and relapse UNIVARIATE MULTIVARIATE survival (months) relapse free interval ... 67 (76%) patients squamous cell carcinoma existed. There were 18 patients with adenocarcinoma, one with bronchioloalveolar carcinoma and two with adenosqua- mous carcinoma. Postoperatively, 23(26.1%) ... Chemotherapy alone was given to two patients, whilst one patient underwent chemotherapy combined with radiation therapy. Univariate and multivariate analysis of prognostic factors Univariate analysis

Ngày tải lên: 09/08/2014, 04:21

... were available at a national teaching course. We report a prospective comparative study of a non small cell lung cancer (NSCLC) case delineated by 120 residents before and after a radioanatomy/radiotherapy ... critical organs (esophagus, heart and spinal cord) Delineation variability has already been analyzed, in prostate cancer [18-19], breast cancer [20], lung cancer [15], and cervical cancer ... Guzel-Szczepiorkowska Z, Pietrzak L, Komosinska K, Sprawka A, Garbaczewska A: Delineation variation of lymph node stations for treatment planning lung cancer radiotherapy Radiother Oncol 2007,85:450-5 16 Chapet

Ngày tải lên: 09/08/2014, 09:21

... potential population stratification, we limited the analyses to Caucasians for genetic analyses Laboratory assays The laboratories selected for this study had high assay precision The laboratories ... each from African Americans, Latinos, Japanese, Americans, Native Hawaiians and Whites), with invasive, non-localized breast cancer SNPs with minor allele frequency >5% overall or >1% in any one ... chromatography [47] at Quest Laboratory, San Juan Capistrano, California Performance of this assay at Quest Laboratory has been extensively tested in prior NHS study samples with hormone stability

Ngày tải lên: 09/08/2014, 14:22

... multithreading (SMT). SMT takes advantage of a modern CPU’s super- scalar architecture. Superscalar processors are able to have multiple instructions operating on separate data in parallel. HTT-capable ... SuperXGA (SXGA) has a resolution of 128 0 × 1 024 and an aspect ratio of 5:4, then WSXGA might have a resolution of 1440 × 900 and a 16:10 aspect ratio Each of these advanced resolutions has a standard ... dissipate heat away from the memory chips and prevent overheating. RIMM Not an acronym, RIMM is a trademark of Rambus Inc., perhaps a clever play on the acronym DIMM, a competing form factor. A

Ngày tải lên: 10/08/2014, 12:21

... Jerjes - waseem_wk1@yahoo.co.uk; Vyas Prasad - vyasprasad@hotmail.com; Panagiotis Kafas - pankafas@yahoo.com; Jesuloba Abiola - ja.abiola@googlemail.com; Bryan Youl - bryan.youl@royalfree.nhs.uk; ... same team, in order to maintain consistency and a standardized inter- pretation of the EMG waveform. Statistical analysis SPSS version 14 and Graph Pad Prism 4.0 statistical soft- ware packages ... discomfort; it also makes the use of local anaesthesia which may interfere with EMG unneces- sary. Knowing that the unilateral group had a high NPS, this may empower the patient and may also have a psy-

Ngày tải lên: 11/08/2014, 20:20