a powerful tool in cancer research
Báo cáo y học: "Gain of a 500-fold sensitivity on an intravital MR Contrast Agent based on an endohedral Gadolinium-Cluster-Fullerene-Conjugate: A new chance in cancer diagnostics"
Ngày tải lên :
26/10/2012, 09:07
... trifluoroacetic acid in water (A) and 60% acetonitrile in water (B) as eluent The conjugate was eluted with a successive linear gradient, increasing from 25% to 60% B-eluent in 49 at a flow rate of ... grey-values and differential relaxation times are unsatisfactory so far, because radiation induced necrosis [58], vital tumor tissue and cerebral metastases are nearly undistinguishable.[51] Additionally, ... slowly added at 0–5°C The resulting deeply colored solution was maintained at room temperature for h Then the organic phase was washed with water, followed by 1N-HCl and again water The organic layer...
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STATISTICAL METHODS IN CANCER RESEARCH ppt
Ngày tải lên :
22/03/2014, 17:20
... International Agency for Research on Cancer (IARC) was established in 1965 by the World Health Assembly as an independently financed organization within the framework of the World Health Organization ... agreements, in national research institutions in many countries The Agency also conducts a programme for the education and training of personnel for cancer research The publications of the Agency are intended ... to a subset of the matched pairs or sets, thus throwing away valuable data Such practices are no longer necessary nor defensible now that flexible analytical tools are available, in particular...
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Artificial Neural Networks - a Useful Tool in Air Pollution and Meteorological Modelling pdf
Ngày tải lên :
29/03/2014, 21:20
... learning The remaining five week data base was again divided into a randomly taken 10% test set for optimization and 90% for training For every station vector and scalar half hour average values ... terrain But SODAR measurements are not always available SO2 air pollution was studied in detail (fourth chapter of this article) in the Šoštanj area of Slovenia In the Šoštanj basin SODAR measurements ... were taken instead of prognostic values A two year data base was available for model construction and verification In this case only one pattern per day is available Therefore two years data give...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
Ngày tải lên :
29/06/2014, 11:20
... now in Phase clinical trials in lymphoma (Cotter et al 1994), and is also assayed as a chemosensitizer for dacarbazine treatment of human melanoma (Janssen et al 1998, 2000) In another approach, ... clearance, two critical parameters for imaging agents In the first aptamer imaging study published, the ability of an aptamer binding to human neutrophil elastase to image inflammation was compared ... [18F]-labeled at its 3' end, and imaged in nonhuman primates (Tavitian et al 1998) Metabolic analysis in plasma sampled at regular time intervals after injection showed a rapid degradation of...
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Báo cáo y học: "Technical phosphoproteomic and bioinformatic tools useful in cancer research" potx
Ngày tải lên :
10/08/2014, 09:22
... bioinformatic-analysis, which mainly includes: Conversion-data format, Spectrum identification with a search engine, Validation of identifications, Protein inference, Organization in local data managements ... in cancer treatment; others show inexplicable focal efficacy The vinca alkaloids are useful for treating lymphoma, neuroblastoma and nephroblastomas, whereas taxol is useful for advanced breast ... demands on the accuracy of quantitation Most MS-based quantitative approaches including SILAC and iTRAQ give relative data, meaning that one state of phosphorylation is determined relative to another...
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báo cáo khoa học: "Atomic force microscopy: a powerful tool for high-resolution imaging of spermatozoa" ppt
Ngày tải lên :
11/08/2014, 00:22
... oscillating force generators Nature 1998, 393:711-714 Sakakibara H, Kojima H, Sakai Y, Katayama E, Oiwa K: Inner-arm dynein c of Chlamydomonas flagella is a single-headed processive motor Nature ... 400:586-590 Sakakibara HM, Kunioka Y, Yamada T, Kamimura S: Diameter oscillation of axonemes in sea-urchin sperm flagella Biophys J 2004, 86:346-352 Tomie T, Shimizu H, Majima T, Yamada M, Kanayama T, ... group Protamines, small arginine-rich protein, are the major DNA-binding proteins in the nucleus of spermatozoa of most vertebrates and package the DNA in a volume less than 5% of a somatic cell...
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báo cáo khoa học: "Quantum dots – a versatile tool in plant science?" pdf
Ngày tải lên :
11/08/2014, 00:22
... In parallel, anti-CF1 signals were detected using an Alexa 488 streptavidin conjugate as control To com- DAPI stainingdetection systems signals for rhodamine) using (a) Somatic and 45S rDNA (red ... Åkerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E: Nanocrystal targeting in vivo Proc Natl Acad Sci U S A 2002, 99:12617-21 Ness JM, Akhtar RS, Latham CB, Roth KA: Combined tyramide signal ... 1% BSA at room temperature (RT) and blocked for 20 minutes in PBS + 3% BSA at RT An antibody from rabbit against CF1 (catalytic portion of the chloroplast H+-ATP synthase), against chloroplasts...
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Báo cáo y học: "Hyperinsulinemia-euglycemia therapy: a useful tool in treating calcium channel blocker poisoning" pps
Ngày tải lên :
12/08/2014, 23:24
... Critical Care Vol 10 No Boyer and Levine failing if the therapy was administered, for example, at the end of cardiopulmonary resuscitation After all, when the myocardium dies, along with ... the treatment of calcium channel blocker poisoning in humans? It may be difficult Although calcium channel blocker poisoning is a common cause of pharmaceutical overdose death in the USA, the ... Hyperinsulinemia/euglycemia therapy in the management of overdose of calcium channel blockers Crit Care 2006, 10:212 Kline J, Leonova E, Raymond R: Beneficial myocardial metabolic effects of insulin during...
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Báo cáo y học: "New perspectives on an old disease: proteomics in cancer research" pdf
Ngày tải lên :
14/08/2014, 07:21
... Hutchinson Cancer Research Center, Seattle, USA), plasma derived from mice that showed microscopic ovarian cancer lesions or metastases was analyzed by a quantitative proteomics approach called ... widely adopted scanning MS approaches that aim at identifying all proteins in a sample, MRM relies on the optimized quantitative detection of selected proteins with increased sensitivity Daniela Dinulescu ... quantify a pre-selected set of particularly interesting or discriminating tryptic peptides in plasma using targeted analytical MS methods such as multiple reaction monitoring (MRM) In contrast...
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advances in cancer research
Ngày tải lên :
20/01/2016, 03:47
... (s.c.) from patients with ovarian carcinoma, laryngeal carcinoma, nasopharyngeal carcinoma, hepatoma, lung carcinoma, and melanoma They injected the IFN-/3 at a dose of lo5 IU per mouse The injections ... show an especially high rate of colony formation suitable for in uitro IFN tests These include colon carcinoma, melanoma, lung carcinoma, breast cancer, ovarian carcinoma, and sarcoma (Kern et al., ... various papillomavirusassociated diseases (juvenile laryngeal papillomatosis, common warts, and condyloma acuminata) Natural IFN-P was first produced in large amounts in 1972-1973 and has since...
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báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
Ngày tải lên :
18/06/2014, 15:20
... cycle in a patient with advanced ovarian carcinoma CRP cycle in a patient with advanced ovarian carcinoma Measured oscillation in L-CRP levels vs time in days in a patient with advanced ovarian cancer ... days apart, and repeated) over time, in late-stage advanced cancer Days Days Days Figure CRP cycle in a patient with advanced melanoma CRP cycle in a patient with advanced melanoma Representative ... 46(10):1423-8 Sawamura M, Yamaguchi S, Murakami H, Kitahara T, Itoh K, Maehara T, Kawada E, Matsushima T, Tamura J, Naruse T: Cyclic haemopoiesis at 7- or 8-day intervals Br J Haematol 1994, 88(1):215-8...
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Báo cáo y học: "RNA interference: more than a research tool in the vertebrates'''' adaptive immunity" ppsx
Ngày tải lên :
13/08/2014, 09:21
... mammalian virus-encoded proteins, such as influenza viral protein NS1 and vaccinia viral protein E3L, have a negative regulatory role on RNA silencing in both plant and insect cells, providing ... Johnson KL, Garcia-Sastre A, Ball LA, Palese P, Ding SW: Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing Proc Natl Acad Sci U S A 2004, 101:1350-1355 ... non-coding RNAs of adenovirus can down regulate RNA silencing in mammalian cells [12] However, one must bear in mind that the double strand nature of the siRNAs can results in an interferon-mediated...
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Báo cáo y học: "High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment"
Ngày tải lên :
26/10/2012, 09:48
... 273-284 49 Powell SN and Bindra RS Targeting the DNA damage response for cancer therapy DNA Repair (Amst) 2009; 8: 1153-1165 50 Shimada M and Nakanishi M DNA damage checkpoints and cancer J Mol Histol ... Tarumi Y, Kadomatsu K, and Takei Y Systemic delivery of siRNA specific to tumor mediated by atelocollagen: Combined therapy using siRNA targeting Bcl-xL and cisplatin against prostate cancer Int ... refractory prostate cancer Urology 2007; 69: 347-351 Ueda T, Suzuki H, Akakura K, Ishihara M, Kamiya N, Komiya A, Shimbo M, Suyama T, Sakamoto S, and Ichikawa T Bisphosphonate and low-dose dexamethasone...
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Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
Ngày tải lên :
31/10/2012, 14:59
... and RNA synthesis, and inosine that will be degraded into hypoxanthine and xanthine and finally into uric acid Hypoxanthine and guanine may enter in a salvage pathway, using hypoxanthine-guanine ... immunogenicity The PEGylation consists in binding with a covalent link a protein (adenosine-deaminase, asparaginase, interferons, granulocyte colonystimulating factor, liposomal doxyrubicin) to poly(ethylene) ... renal impairment Standard measures to prevent and treat hyperuricemia include allopurinol and alkalinization, associated with an aggressive hydration Rasburicase presents various features that...
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Tài liệu ANSYS Mechanical- A Powerful Nonlinear Simulation Tool pdf
Ngày tải lên :
23/12/2013, 01:16
... nonlinear analysis and design more often while minimizing approximations Analysts and designers now expect nonlinear analysis capabilities in general-purpose programs such as ANSYS Mechanical ANSYS, ... isoparametric fully integrated elements is limited In linear or nonlinear analyses, serious locking may occur As a general analysis tool, ANSYS Mechanical uses elements in wide range of applications ... effects using the shell element Figure Stamping (ANSYS LS-DYNA) and springback analysis (ANSYS Mechanical) Figure Nonlinear collapse study of a beverage can Common Features ANSYS Mechanical data input...
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Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx
Ngày tải lên :
14/02/2014, 21:20
... novel approaches to validation studies; advanced informatics and information flow; standardization of reagents and assays and data reporting; and creation of standard statistical and computational ... cancers, gastrointestinal and other associated cancers, lung and upper aerodigestive cancers and prostate and urologic cancers, each have biomarkers in prevalidation and validation phases in which ... ovarian cancer with serum markers, such as CA-125, transvaginal ultrasound, or pelvic examinations would result in decreased mortality from ovarian cancer Cervical Cancer Cervical cancer is a...
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Tài liệu StrategieS for SucceSS: How to Write a Grant in Cancer CAM docx
Ngày tải lên :
14/02/2014, 22:20
... Methodological Issues in Cancer CAM Research Multidisciplinary Approaches in Cancer Treatment Investigators are often interested in investigating multidisciplinary approaches in cancer care The advantages ... subgroup analyses See also valid analysis Asian A person having origins in the original peoples of the Far East, Southeast Asia, or the Indian subcontinent including, Cambodia, China, India, Japan, ... areas in cancer research training or cancer research career development at the MSI These partnerships may also focus on cancer research and target areas in cancer education for or cancer outreach...
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Tài liệu Cancer Research in ICMR Achievements in Nineties ppt
Ngày tải lên :
15/02/2014, 04:20
... for health education at Karnataka was 8.3% in the area with clinical examination in the field, and 22.0% in the area with only health education in the field The coverage for health education at ... ax Ea M ax t( (M en er tm nc ea Ca Tr of ge ed wl no K Pre-training Post-training Adequacy of Pap Smears at Karnataka Centre 3% 97% Adequte Smears Inadequate Smears The feasibility of involving ... Gujarat was near total The coverage for clinical examination of cervix was more in Gujarat, if the examination was carried out in the field (28.3% vs 0.8%) The coverage for clinical examination...
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Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf
Ngày tải lên :
19/02/2014, 12:20
... glycosylation pattern associated to malignancy We found in fact that NeuAca2-3Galb1-3[Fuca1-4]GlcNAcb1-3Gal and NeuAca2-3Galb1-3GlcNAcb1-3Gal are the main oligosaccharides released by endo-b-galactosidase ... b1,3galactosidases, giving rise to a disaccharide and a monosaccharide, and was thus identified as a mixture of Galb1-4[Fuca1-3]GlcNAcb1-3Gal and Galb1-3[Fuca1-4]GlcNAcb1-3Gal The calculated amounts ... [30] These data match the finding that CEA synthesized by normal mucosa has abundant N-linked type chains due to b3Gal-T5 activity, and that are replaced by poly N-acetyllactosamines in cancer where...
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