... right partner and worried about balancing family and work amid mounting job demands and a lack of caretaking supports, they are developing second-best fallback strategies as insurance against their ... This page intentionally left blank chapter one I | The Shaping of a New Generation t is a cool, clear morning in Oceanside Terrace, a working-class suburb where American flags are almost as plentiful ... having all the fighting and that element in the house.” As Josh reached school age, his home life changed dramatically His mother took a job as an administrator in a local business and, feeling...
Ngày tải lên: 10/06/2014, 21:30
... and RNA synthesis, and inosine that will be degraded into hypoxanthine and xanthine and finally into uric acid Hypoxanthine and guanine may enter in a salvage pathway, using hypoxanthine-guanine ... immunogenicity The PEGylation consists in binding with a covalent link a protein (adenosine-deaminase, asparaginase, interferons, granulocyte colonystimulating factor, liposomal doxyrubicin) to poly(ethylene) ... renal impairment Standard measures to prevent and treat hyperuricemia include allopurinol and alkalinization, associated with an aggressive hydration Rasburicase presents various features that...
Ngày tải lên: 31/10/2012, 14:59
Tài liệu Toward a New Literacy of Cooperation in Business MANAGING DILEMMAS IN THE 21ST CENTURY pdf
... basic IT strategies that have dominated organizations over the last 50 years Narrow-platform standards and organizational firewalls are replaced by inter-operability standards and point-topoint ... the basic patterns and mechanisms of symbiosis and parasitism can provide both medical and organizational frameworks for global teams to cooperate in averting disasters and managing outbreaks ... public and private knowledge is a key variable in maintaining cooperative patterns Toward a New Literacy of Cooperation in Business 29 Organizational Choices: Seven Ways to Tune Up for Cooperation...
Ngày tải lên: 18/02/2014, 00:20
Tài liệu UN Global Compact-Accenture CEO Study A New Era of Sustainability in Consumer Goods pdf
... subsidiaries 32% 25% Including sustainability objectives in employee performance assessment 27% Investing in training employees to manage sustainability 26% 25% Incorporating sustainability issues into ... and a determination to integrate sustainability objectives into core business CEOs’ belief in the centrality of sustainability means that their companies are beginning to take real and innovative ... unnecessary packaging and wastage, as well as using more sustainable materials Leading companies are setting ambitious targets: for example, Procter & Gamble aim to use 100 percent renewable or...
Ngày tải lên: 18/02/2014, 21:20
Research Program of the Partnership for a New Generation of Vehicles doc
... Sandia National Laboratories, Los Alamos National Laboratory, National Renewable Energy Laboratory, Argonne National Laboratory, Oak Ridge National Laboratory, and the Department of Energy Headquarters ... CLARENDON, Financial Associate PANOLA GOLSON, Project Assistant ANA-MARIA IGNAT, Project Assistant SHANNA LIBERMAN, Project Assistant NAE = National Academy of Engineering viii Acknowledgments The ... in the car companies are meeting this need ADEQUACY AND BALANCE OF THE PNGV PROGRAM The adequacy and balance of the PNGV R&D program are difficult to assess Goals and are stated in qualitative...
Ngày tải lên: 06/03/2014, 15:20
Báo cáo khoa học: Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling pdf
... downregulation was calculated for the GFP+ and GFP) populations (B) Apoptosis in GFP+ (red) cells was assessed by annexin V staining and FACS analysis Nonstimulated cells are shown in gray The data ... z-VAD Whereas cells incubated with FADD trafficking and CD95 signaling z-VAD alone again demonstrated significant downregulation of surface CD95 expression at 30 followed by an increase at 60 min, ... cytoplasm is independent of CD95 receptor internalization, DISC assembly at endosomes and caspase activation, our data indicate that CD95 triggering induces additional, plasma membrane proximal...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Evidence of a new phosphoryl transfer system in nucleotide metabolism doc
... classical ATP formation pathways and the AMP–AMP phosphotransferase network The latter reaction may represent a compensatory mechanism for maintaining and increasing ADP to the levels necessary ... revealed the disappearance of ADP and the formation of an ATP peak, which was identified in the chromatogram using the same criteria as for ADP and inosine Enzyme assays and identification of reaction ... interfering contaminants The non-retained fraction contained MK and AdK activities ADA was eluted using a linear gradient with the same buffer spiked with m NaCl in five column volumes MK, AdK, ADA and...
Ngày tải lên: 23/03/2014, 06:20
WORLD INVESTMENT REPORT 2012 Towards a New GeNeraTioN of iNvesTmeNT Policies potx
... Dip and Ganu Subramanian Production and dissemination of WIR12 was supported by Elisabeth Anodeau-Mareschal, Severine Excoffier, Rosalina Goyena, Natalia Meramo-Bachayani and Katia Vieu The manuscript ... Monaco in Europe; Bahrain, Liberia and Seychelles in Africa; and the Cook Islands, Maldives, the Marshall Islands, Nauru, Niue, Samoa, Tonga and Vanuatu in Asia; as well as economies in the Caribbean ... Caribbean such as Anguilla, Antigua and Barbuda, Aruba, Barbados, Belize, the British Virgin Islands, the Cayman Islands, Dominica, Grenada, Montserrat, the Netherlands Antilles, Panama, Saint Kitts...
Ngày tải lên: 30/03/2014, 12:20
báo cáo hóa học:" Research Article Strong Convergence of a New Iterative Method for Infinite Family of Generalized Equilibrium and Fixed-Point Problems of Nonexpansive Mappings in Hilbert Spaces" pptx
... nonexpansive mappings,” Journal of Mathematical Analysis and Applications, vol 298, no 1, pp 279–291, 2004 G Marino and H.-K Xu, A general iterative method for nonexpansive mappings in Hilbert spaces,” ... spaces,” Journal of Mathematical Analysis and Applications, vol 318, no 1, pp 43–52, 2006 Y Yao, A general iterative method for a finite family of nonexpansive mappings,” Nonlinear Analysis: Theory, ... nonexpansive mappings and inversestrongly monotone mappings,” Nonlinear Analysis: Theory, Methods & Applications, vol 61, no 3, pp 341–350, 2005 21 W Takahashi, Nonlinear Functional Analysis, Fixed Point...
Ngày tải lên: 21/06/2014, 11:20
Báo cáo khoa học: "Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats" pdf
... htob erusaem ot desu saw )ASU ,tneligA( nevo nmuloc a dna ,)ASU ,tneligA( relpmasotua na ,)ASU ,tneligA( ressaged a ,)ASU ,tneligA( pmup a ,)ASU ,tneligA( rotceted VU yarra edoidotohp a gnidulcni ... gk/gm 02 fo noitartsinimda suonevartni retfa 2050-PV fo sretemarap citenikocamrahP elba T 562 star ni tnega VIH-itna wen a sa gurdorp dehcatta-dica onima eht fo ytilibaliavaoiB nwohs sah ,siht ot ... LA1050-PV rof alumrof eninala dica onima eht yb ytilibaliavaoib fo tnemevorpmi ehT etadidnac gurdorp wen a rof yrotcafsitas erew amsalp ni noitartnecnoc fo ecnanetniam eht dna ,mrof evitca na...
Ngày tải lên: 07/08/2014, 23:22
Báo cáo khoa học: "Commissioning and early experience with a new-generation low-energy linear accelerator with advanced delivery and imaging functionalities" doc
... Bellinzona (Switzerland) e-mail: giorgia.nicolini@eoc.ch Abstract Background: A new- generation low-energy linear accelerator (UNIQUE) was introduced in the clinical arena during 2009 by Varian ... accurate and safe delivery of RapidArc plans Key words: UNIQUE linear accelerator, RapidArc, Beam Commissioning Background During 2009, a new single-energy linear accelerator for radiotherapy was introduced ... Aletti P, Bey P, Chauvel P, Chavaudra J, Costa A, Donnareix D, Gaboriaud G, Lagrange JL, Manny C, Ponvert D, Rozan R, Valinta D, Van Dam J: Recommendations for a quality assurance programme in...
Ngày tải lên: 09/08/2014, 09:21
Báo cáo khoa học: "Identification and characterization of a new E3 ubiquitin ligase in white spot syndrome virus involved in virus latency" pot
... signaling pathways involved in latency regulation [25] As a RINGcontaining E3 ubiquitin ligase, WSSV403 is able to interact with its substrates besides E2 conjugating enzymes and to mediate degradation ... can interact with a shrimp protein phosphatase WSSV403 can interact with a shrimp protein phosphatase WSSV403 was found to interact with shrimp PPs in yeast two hybrid Cotransformed yeast was ... from WSSV DNA, encoding a protein of 641 aa An initial characterization of the putative protein encoded by WSSV ORF403 (AF332093) revealed the presence of a RING finger domain similar to those...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: " Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons" pdf
... the statistical analysis CL and MF participated in the design of the study and the data interpretation KM recruited patients, obtained medical data and assessed results All authors read and approved ... Germany; equivalent to about TU of PPD-S) was injected intradermally into the volar aspect of the forearm and transverse induration diameter was measured 72 hours later Individuals performing ... of infectiousness were not included in the study All individuals agreed to participate in the study by written consent Each individual was interviewed by trained public-health staff using a standardized...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo y học: " Isolation of a new HIV-2 group in the US" pptx
... provided valuable demographic data RG, AG, CA, and PAM amplified gag and performed the phylogenic analysis All authors read and approved the final manuscript Acknowledgements This work was made possible ... that the antibody tests are false positives These data demonstrate that a pathogenic, novel strain of HIV-2 is circulating, at least, within Sierra Leone Health care providers in Sierra Leone and ... by funding from the Saint Michael Infectious Diseases Association and Saint Michael's Medical Center References Furthermore, the commercial assay for establishing the existence of active infection,...
Ngày tải lên: 13/08/2014, 05:21
Laying the foundations a new era for rd in the middle east
... years ago.” Better co-ordination between regulators that review marketing authorisation and those that regulate clinical trials should lead to an increasing volume of late-stage R&D taking place ... geographical good fortune Situated halfway between Europe and Asia, and with fast-growing regions such as the Asia Pacific region and Africa within striking distance, the Middle East has an enviable ... world During the so-called Islamic golden age, scholars and scientists across the Middle East and North Africa made major advances in mathematics, astronomy, medicine and engineering But as the...
Ngày tải lên: 06/12/2015, 23:04
InTech city climber a new generation wall climbing robots
... Magnetic ADCINA0 ADCINA1 ADCINA2 ADCINA3 Accelerometer GPIOB6 ADCINA7 ADCINB5 ADCINB6 ADCINB7 Host Computer ADCINA4 ADCINA5 ADCINA6 SCI -A RS232 GYRO MARG SCI-B RS232 Decoder Receiver Fig 20 Hardware ... http://www.intechopen.com/books/climbing_and_walking_robots_towards _new_ applications/cityclimber a_ new_ generation_ wall-climbing_robots InTech Europe InTech China Slavka Krautzeka 83 /A No.65, Yan An Road (West), Shanghai, 200040, China ... was read into Fluent for the aerodynamics analysis In Fluent, the solver was defined as “Steady State” and the type of flow was defined as a “K-Epsilon”, and the material as air Fig and (static...
Ngày tải lên: 21/09/2016, 23:10
Báo cáo sinh học: " Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases" doc
... CytoDyn Amerimmune Pharmaceuticals, Inc TIPRANAVIR AAI International, AnaaiPharma Company MedImmune MedImmune MedImmune Inspire Pharmaceuticals Genital Warts HPV Hepatitis B Hepatitis B Hepatitis ... OraQuick HIV-1 Cytolin Tipranavir HXB MEDI-491 Synagis™ (Palivizumab) Numax INS37217 Intranasal MedImmune Nabi Biopharmaceuticals Protein Design Labs XTL Biopharmaceuticals Ltd Nabi Biopharmaceuticals ... limited by insufficient efficacy and unfavorable pharmacokinetics MAbs have increasingly gained favor in large part because of the development of chimeric, humanized, and human antibodies have reduced...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học:" Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases" pdf
... CytoDyn Amerimmune Pharmaceuticals, Inc TIPRANAVIR AAI International, AnaaiPharma Company MedImmune MedImmune MedImmune Inspire Pharmaceuticals Genital Warts HPV Hepatitis B Hepatitis B Hepatitis ... OraQuick HIV-1 Cytolin Tipranavir HXB MEDI-491 Synagis™ (Palivizumab) Numax INS37217 Intranasal MedImmune Nabi Biopharmaceuticals Protein Design Labs XTL Biopharmaceuticals Ltd Nabi Biopharmaceuticals ... limited by insufficient efficacy and unfavorable pharmacokinetics MAbs have increasingly gained favor in large part because of the development of chimeric, humanized, and human antibodies have reduced...
Ngày tải lên: 20/06/2014, 04:20