a moment that is frozen as we hang in time
Analyse criterias when there is an m and a and take a company that you know as an example to analyse your criterias analyses
... Topic: Analyse criterias when there is an M& ;A and take a company that you know as an example to analyse your criterias analyses. Geography Nokia is selling its headquarters in Finland for ... ã Affect adverse selection and moral hazard problems in M& ;A ã Hinder acquisitions efforts to assess the true value ã Hamper acquisitions ability to manage contractual relationships ã Affect ... skype ã Renowned for quality skype call and free ã Xbox phonelead the camara but also will always lead in the mobile entertainment industry Goals "+, ã .$/ "-' ã 0$! $/ 1. / ...
Ngày tải lên: 08/05/2014, 17:42
báo cáo khoa học: "A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma" ppt
Ngày tải lên: 11/08/2014, 00:22
A pathway that links reproductive status to lifespan in Caenorhabditis elegans pptx
... One could imagine that the insulin pathway is down- stream of the somatic gonad; that is, that the so- matic gonad extends lifespan in germline-deficient animals by inhibiting insulin/IGF-1 signaling. ... conditions in uence lifespan are now under investigation in many labs, and in many cases, genetic pathways employing classical regu- latory proteins, such as kinases and transcription factors, play important ... not known in detail; but at least part of the story has begun to emerge (and is summarized in Figs. 2 and 3). First, the pathway that triggers DAF-16/FOXO nuclear localization is at least partially distinct from...
Ngày tải lên: 28/03/2014, 16:20
Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot
... Murakami, Y., Matsufuji, S., Kameji, T., Hayashi, S., Igarashi, K., Tamura, T., Tanaka, K. & Ichihara, A. (1992) Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. ... Kobayashi, S., Hayashi, T., Matsufuji, S., Murakami, Y. & Hayashi, S. (1997) Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor . Biochim. Biophys. Acta ... Matsufuji, S., Matsufuji, T., Miyazaki, Y., Murakami, Y., Atkins, J.F., Gesteland, R.F. & Hayashi, S. (1995) Autoregulatory frame- shifting in decoding mammalian ornithine decarboxylase anti- zyme....
Ngày tải lên: 22/02/2014, 04:20
Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt
... nondenaturing and transverse urea gradient PAGE, and activity was assessed against tPA [6]. Complex formation assays Wild-type and Ser52Arg neuroserpin were incubated i n various ratios with tPA at ... Ser52Arg neuroserpin was more resistant to cleavage, a s there was always a significant proportion of Ser52Arg neuroserpin that remained uncleaved even after i ncubation for 1 h a t a tPA to Ser52Arg ... temperature but is inactive as a proteinase inhibitor. This results in part from the reactive loop being in a less accessible conformation to bind to the target enzyme, tissue plasminogen activator. These...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays pdf
... Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays Greg B. G. Moorhead*, Sarah E. M. Meek, Pauline Douglas*, Dave ... change in A 340 was subtracted from a control with no enzyme, which was run parallel to each assay. The assays which contained ATP in stage I were diluted 100-fold for stage II. All assays were ... (GS) and nitrate reductase (NR) was highly purified from cauli- flower (Brassica oleracea var. botrytis) extracts. The final preparationcontainedanacyl-CoAoxidaseandasecond protein of the plant nucleotide...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Molecular characterization of a novel nuclear transglutaminase that is expressed during starfish embryogenesis ppt
... ACATGTACATGTATATCACTTTGAACTGGTTTTCATTAAAAAAAAAAAACCATCAATTTG 2459 AGAAGAAACAATTACTTCTTAAGTCAATTAATTTTTCTAGAAATGCAAAAGATATTCCCC 2519 TTAACAGCTGTTTGAAATGAGGCCTCGGTCTCAAGTTTAAGAGTGCCCCCATATGTAAGC ... TAAAAAGCTCCAGGAAGTTGACCCAGAAGAAATTTGTTAAGAGTTCACGGATAAGCAAGG 2639 TATTTGGATAAGGTGCATTTGTACATTTTGTGTGTACTGGTTTAGTGTAGAATTTAATTT 2699 TTTTTGGTTAATTCTGTCACAAGAACATAATTCTATGGTTACTACACAATGTTGCATCCC ... CCGCAGCTCAGTGGTGTCAAGGCCCATGTCACACTCAATGTCAAGAGTGCTTAATTTGCT 2279 P Q L S G V K A H V T L N V K S A * ATGCGAGGTCAGCATTTATCCAACCAGAAGCTTCACGGAGCTAGCTGGGCAAGGAAATTT 2339 GATAATCGCAAGAAATAATTTCCCCCCAAAAACAAAAGGTTGTTGGCTGAAAATACTTCT 2399 ACATGTACATGTATATCACTTTGAACTGGTTTTCATTAAAAAAAAAAAACCATCAATTTG...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
... 5Â-AAACCAGCCATGAATGAAAT-3Â) and with actin primers (forward primer: 5Â-GTTGGGAT GAACCAGAAGGA-3Â; reverse primer: 5Â-GAACCA CCGATCCAGACACT-3Â) as a control. Reactions with no DNA added served as a ... Ca 2+ application increased the kinase level and the response was faster than that obtained following stress application. Low temperature- mediated, but not salinity-mediated stress kinase increase was inhibited ... protein kinase with a molecular mass of 72 kDa was identified in pea. The pea kinase (PsCCaMK) was upregulated in roots in response to low temperature and increased salinity. Exogenous Ca 2+ application...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... D ATTTGAACTGTGCCAGGACTGGGAGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGAGAGGAGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGAAGGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAAGGAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAGGGATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAAAAGGGTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAAAAATTGGGGATCT Mut ... GHIF ATTTGAACTGTGCCAATGCTGGGAGAAAAAATTTAAGATCT CHRup MYB1 ATTTGAACTAGACCAATGCTGGGAGAAAAAATTTAAGATCT Mut A ATTTGAACTGTGAAGATGCTGGGAGAAAAAATTTAAGATCT Mut B Mut C Mut D ATTTGAACTGTGCCAGGACTGGGAGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGAGAGGAGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGAAGGAAAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAAGGAAAATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAGGGATTTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAAAAGGGTAAGATCT ATTTGAACTGTGCCAATGCTGGGAGAAAAAATTGGGGATCT Mut ... 5Â-GGCGGATCCAAGCCAGTGGTTGTTAAT AC-3Â and 5Â-GCCTCGAGAATCAAGTGTCCCTGCACC T-3Â (LIN-54-DN); 5Â-GCGGATCCGAGGTGGTGCCAG CTGAG-3Â,5Â-GCTCTAGAGAATGGAAGCCGTGCCT G-3Â,5Â-GCTCTAGATTGGCAGATGCAGCTGAAGTA- 3Â and...
Ngày tải lên: 23/03/2014, 04:20
Báo cáo khoa học: The Drosophila jumonji gene encodes a JmjC-containing nuclear protein that is required for metamorphosis pot
... used were as follows: cycD-F, 5Â-GGGATCCCA CATTGTATTCG-3Â; cycD-R, 5Â-ACGGAGCTTTGAAG CCAGTA-3Â; cycE-F, 5Â-AAGGTGCAGAAGACGCA CTT-3Â; cycE-R, 5Â-AATCACCTGCCAATCCAGAC-3Â; cdk4-F, 5Â-TACAACAGCACCGTGGACAT-3Â; ... encodes a JmjC-containing nuclear protein that is required for metamorphosis Nobuhiro Sasai 1,2,3, *, Yasuko Kato 2,3 , Gaku Kimura 2,3 , Takashi Takeuchi 4 and Masamitsu Yamaguchi 2,3 1 Venture Laboratory, ... Alexa-488-conjugated anti-rabbit IgG (1 : 400) for 2 h at 25 °C. DNA was stained with DAPI. Semiquantitative RT-PCR Total RNA was extracted with Sepasol RNA I (Nacalai, Kyoto, Japan). First-strand cDNA was...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: A designed curved DNA segment that is a remarkable activator of eukaryotic transcription potx
... 5Â-GTTTTTCATG TTTTTCATGTTTTTCATGTTTTTCAC-3Â and 5Â-GTG AAAAACATGAAAAACATGAAAAACATGAAAAAC-3Â, was inserted into the PmaCI site of pLHC4 ⁄ TLN [12] by blunt-end ligation. After a conventional cloning and screen- ing procedure, a ... and pLHC40 TLN-6, respectively. Group II Synthetic oligonucleotides 5Â-TCAGTTTTTCAGTCAG TTTTTCAGTCAGTTTTTCAGTCAGTTTTTCAC-3Â and 5Â-GTGAAAAACTGACTGAAAAACTGACTGAAAAAC TGACTGAAAAACTGA-3Â were annealed ... recombinase. After cell cloning, T20- deletion clones were selected based on PCR analysis using primers 5Â-GCGCCGGATCCTTAATTAAG-3Â and 5Â-GG AGGTAGATGAGATGTGACGAACG-3Â. The established cell lines were...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: NARG2 encodes a novel nuclear protein with (S/T)PXX motifs that is expressed during development docx
... gagt … ccac ag GGATGT 1.4 3 105 a TAACAG gt aata … ttcc ag ACGTAT 6.5 4 250 TATCTG gt atgt … taac ag GATATG 0.89 5 120 ACGGAG gt aaaa … tccc ag CAACTC 1.7 6 138 GTTTTG gt aaga … attt ag GGCAGT 0.52 7 117 ... 7.7 4 262 a TACTTG gt atgt … aatc ag GATATG 1.3 5 120 a ACAGAG gt aaaa … tctc ag AAAATT 9.9 6 138 GCATTG gt aagg … attt ag GGCAGT 1.2 7 117 CATTAT gt aagt … tttc ag GATATT 0.17 8 160 TTGCAG gt ttgt … ttta ... ttta ag GTTCAA 1.2 9 182 ATGGAC gt atgt … cata ag ATGTCC 3.8 10 994 AAGGAC gt aagt … ttaa ag GATTGC 0.70 11 176 AGAAGA gt aagt … ttgc ag CAATTT 5.4 12 130 ATGTTG gt aagt … tttt ag GGCATA 6.3 13 85...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents pdf
... QLQRDALRHFAPCQPRARGLQEARAALEPASEPGFAARLLTQRICLERAEAGPLGVAGS MOUSE R3E 178 ARVLDLAYEKRVSVRWSADGWRSLRESPASYAGPAPSPPRADRFAFRLPAPPVGGTLLF RAT R3E 178 ARVLDLAYEKRVSVRWSADGWRSLRESPASYAGPAPAPPRADRFAFRLPAPPVGGALLF HUMAN ... was subtrac- ted. Error bars indicate the SEM for assay of three liver lysates, each assay being performed in triplicate. (C) Comparison of the total phosphorylase phosphatase activity associated ... RGRRARSAPAGGGGARAPRSRSPDTRKRVRFADALGLELAVVRRFRPGELPRVPRHVQI MOUSE R3E 119 QLQRDALRHFAPCPPRARGLQEARVALEPALEPGFAARLQAQRICLERADAGPLGVAGS RAT R3E 119 QLQRDALRHFAPCPPRTRGLQDARIALEPALEPGFAARLQAQRICLERADAGPLGVAGS HUMAN R3E...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo Y học: A nonphosphorylated 14-3-3 binding motif on exoenzyme S that is functional in vivo pot
... reverse- phase HPLC and characterized by MS, corresponding to the putative 14-3-3 binding domain of ExoS (QSGHSQG LLDALDLASKP), was purchased from Agrisera AB (Sweden). Plasmids pGEX-ExoS(SD), was derived ... defined consensus-binding motif. Some well-described 14-3-3 bind- ing partners include the protein kinases Raf-1 [8], kinase suppressor of Ras-1 [9], Ask1 [10], mitogen-activated protein kinase/extracellular ... signal-regulated kinase kinase [11], Bcr [12] and protein kinase C [13]. In addition, 14-3-3 proteins also interact in a phospho-specific manner with the pro-apoptotic protein Bad [14] and the transcription...
Ngày tải lên: 31/03/2014, 08:20
the nothing that is, a natural history of zero - robert kaplan
... the West. In this book you will see it appear in Sumerian days almost as an afterthought, then in the coming centuries casually alter and almost as casually disappear, to rise again ... you have to say that Archimedes' estimate wasn't all that bad. This is a spectacular application of the Greek insight that the world afar can be grasped by analogy to the ... acquaintance claimed that the last number of all was 23,000. 'What about 23,000 and one?' she was asked. After a pause: 'Well, I was close.' Under this Adam Impulse...
Ngày tải lên: 05/06/2014, 11:23
n order to better illustrate the necessary functions and features of this application, a rainwater retention basin is assumed as example
... illustrate the necessary functions and features of this application, a rainwater retention basin is assumed as example. Measures for efficient maintenance should be taken for optimizing plant availability ... plant availability and efficiency. Alarm messages for instance in case of malfunction of the lock should be sent to the service personnel as an SMS message via this GSM modem. Following use cases are considered ... Watchdog [006] - Programas demo do PLC S7-1200 da SIEMENS (Sima!c) Wireless Signaling and Switching per SMS with S7-1200 controller (CE-X25 ) Task description A GSM modem SINAUT MD720-3 is...
Ngày tải lên: 01/07/2014, 21:04