... Pseudomonas aeruginosa population Journal of Mathematical Biology 2005, 51:557-594 40 Anguige K, King JR, Ward JP: A multi-phase mathematical model of quorum sensing in a maturing Pseudomonas aeruginosa ... model biofilms, including stochastic individual based models, stochastic cellular automata models, and a variety of deterministic partial differential equation models Some examples for such approaches ... Janakiraman V, Englert D, Jayaraman A, Baskaran H: Modeling growth and quorum sensing in biofilms grown in microfluidic chamber Annals of Biomedical Engineering 2009, 37(6):1206-1216 37 Vaughan...
Ngày tải lên: 13/08/2014, 16:20
... suggests a primary patency of 85% for AV fistulas at one year and 75% at two years, whereas the ePTFE graft patency can be as low as 50% after one year and 20% at two years These data exclude fistulae ... many different human or animal models Whenever such data were not available, we estimated the order of magnitude of the parameters and made choices that gave biologically reasonable results Page ... computational experiments and data) this model can be (expanded and) used by clinical researchers as a testbed for exploring and evaluating various therapies that can target both the traditional and...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: " A mathematical model of glutathione metabolism" pps
... submitted manuscript Additional material 14 15 16 17 Additional file Supplementary Material – Model Details for A Mathematical Model of Glutathione Metabolism A full description of the mathematical model ... effects of oxidative stress, particularly as applied to Down syndrome and autism No mathematical model can track all of the variables that might affect a complex biochemical system such as glutathione ... One-carbon metabolism and the transsulfuration pathway One-carbon metabolism and the transsulfuration pathway Rectangles enclose the names or acronyms of substrates that are variables in the model...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "A mathematical model of the euglycemic hyperinsulinemic clamp" ppsx
... mathematical modeling, statistical analysis, drafting of the manuscript; ADG: mathematical modeling, drafting of the manuscript; SP: mathematical modeling; Ferrannini E, Mari A: How to measure ... state variables of which the values are known at each time; the state variables and the parameters are defined in tables and The model is diagrammatically represented in Figure Equations (1) and ... [8], carefully measured average glucose uptake rates at two hours are nonlinearly related to increasing levels of plasma insulin, and from the reported data, glucose uptake may approach a maximal...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo hóa học: " Development of a mathematical model for predicting electrically elicited quadriceps femoris muscle forces during isovelocity knee joint motion" potx
... a parabolic manner and was modeled as A( θ) = a( 40 - θ)2 + b(40 - θ) + A4 0, (11) where A4 0 is the value of A at 40° of knee flexion, and a and b are constants that need to be identified for each ... FES are probably complex One way to assist the search for the optimal pattern is to use mathematical models that can predict forces accurately to a range of physiological conditions and stimulation ... speed of 200°/s The values of each of the parameters (a, b, A4 0, τ1, τ2, KM, V1, and V2) were then obtained as described above For each of the above relationships we fitted the data with a linear...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo y học: " The function of 7D-cadherins: a mathematical model predicts physiological importance for water transport through simple epithelia" pdf
... Takamura M, Yamagiwa S, Wakai T, Tamura Y, Kamimura H, Kato T, Tsuchiya A, Matsuda Y, Shirai Y, Ichida T, Ajioka Y, Aoyagi Y: Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma ... http://www.tbiomed.com/content/8/1/18 modeling and the derivation of the initial differential equations, did some calculations and characterizations of the analytical model and he wrote most of the manuscript All authors read and ... 2Department of Mathematics I, RWTH-Aachen University, Aachen, Germany 3Lehrstuhl A Mathematik, RWTH-Aachen University, Aachen, Germany Authors’ contributions MA did most of the calculations and the analytical...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "A continuum mathematical model of endothelial layer maintenance and senescence" ppsx
... homing, and damaging factors such as cellular senescence and death Our model involves a system of differential equations that offers a deterministic view of the average dynamics of large EC populations, ... and death rate parameters on cell generation, our model predicts a narrow distribution of cell densities peaking at a particular cell generation – it is this peak that characterizes the age of ... corresponds to a Gaussian-like distribution of EC generations with a distribution peak that moves towards senescence at a rate that can be manipulated by varying the rate parameters of cellular processes...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH" ppt
... presence and absence of external calcium We note that Heinze et al, [2], created a mathematical model for LH release that reproduces some data for pulsatile administration of GnRH Their model, ... the absence of hormone, the fraction of open channels increases at a linear rate of v2 = 0.002 min-1 and has a maximum value of Thus, immediately a five minute pulse of nM GnRH, 10% of the channels ... that there is a slow increase of approximately 43% of the concentration GQ associated with the membrane during the exposure Figure Experimental data of Baird et al.[22] Experimental data of Baird...
Ngày tải lên: 13/08/2014, 22:22
Báo cáo y học: " A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies" ppt
... developed a multiscale mathematical model of these processes to study the efficacy of radiotherapy Several mathematical frameworks have been developed to model avascular and vascular tumor growth ... tumors to irradiation [9] Nowadays, computational power allows us to build mathematical models that can integrate different aspects of the disease and can be used to investigate the role of complex ... because of hypoxia, through SMAD gene activation Finally, according to the model parameters, APC and SMAD/RAS Page of 19 (page number not for citation purposes) Theoretical Biology and Medical Modelling...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"
... sequence of rat TLR4 (GenBank accession NM_019178) were: 5’-CUACCAACAGAGAGGAUAU-3” (siRNA1), 5’-GUCUCAGAUAUCUAGAUCU-3’ (siRNA2), 5’-GAGCCGGAAAGUUAUUGUG-3’ (siRNA3) All siRNAs were chemically synthesized ... system (Amersham Pharmacia Biotech, Uppsala, Sweden) Histone3 (Sigma, St Louis, MO, USA, 1:500) was used as an internal control Statistical analyses Data are expressed as mean ± standard deviation ... once daily for days, starting from day before CCI surgery Evaluation of tactile allodynia and thermal hyperalgesia The paw withdrawal latency (PWL) to radiant heat and paw withdrawal threshold (PWT)...
Ngày tải lên: 25/10/2012, 11:48
Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx
... Pro transmission scanner (Epson, Nagano, Japan) and analyzed with imagemaster 2d platinum software, version 5.0 (GE Healthcare) Spots were detected automatically by the software and manually refined; ... Germany) Capillary voltage was 1.5–2 kV and a dry gas flow rate of 10 LÆmin)1 was used with a temperature of 230 °C The scan range was 300–1800 m ⁄ z The tandem mass spectra were annotated and peak list ... eukaryotic initiation factor 5A (eIF 5A) , parathymosin, L7 ⁄ L12, annexin A2 , annexin A5 , aldolase A, fascin and peroxyredoxin 1] displayed quantitative differences, regardless of whether or not a- synuclein...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc
... Systems Modelling Database and can be accessed at http://jjj.biochem.sun.ac.za/ database/curien/index.html free of charge Fig Phser branch-point in the aspartate-derived amino acid biosynthetic pathway ... can be calculated as follows: ELISA assays were carried out using rabbit antibodies raised against the recombinant proteins [12,14] and puried proteins as standards We measured that an extract ... with KALEIDAGRAPH (Abelbeck Software, Reading, PA, USA) A series of constant or changing values were generated for the dierent input variables and the calculations were done using the appropriate...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu Báo cáo khoa học: "A Shallow Model of Backchannel Continuers in Spoken Dialogue" potx
... placing a backchannel continuer they actually realize Our model could potentially be improved by adding words to parts -of- speech in the language model; Ward and Tsukahara (2000) suggest that about ... carrying out a human evaluation of these models it would be hard to decide between a Three Trigram model with a pause threshold of 600ms and a Ten Trigram model with a threshold of 900ms Evaluation ... what the humans in the corpus One difficulty with evaluating a model such as ours is that human speakers differ markedly in their own backchanneling behaviour As Ward and Tsukahara (2000) remark,...
Ngày tải lên: 22/02/2014, 02:20
Báo cáo khoa học: "A Hierarchical Model of Web Summaries" docx
... summaries, this model can be readily adapted to any Web-related content that can be seen as a mixture of the component topics appearing along a paths in the hierarchy Such model can become a key ... (SIGIR’00), pages 144–151 David M Blei and J Lafferty 2009 Topic models In A Srivastava and M Sahami, editors, Text Mining: Theory and Applications Taylor and Francis David M Blei, Andrew Ng, and Michael ... USA ACM Joseph Reisinger and Marius Pa¸ca 2009 Latent varis able models of concept-attribute attachment In ACLIJCNLP ’09: Proceedings of the Joint Conference of the 47th Annual Meeting of the ACL...
Ngày tải lên: 07/03/2014, 22:20
Báo cáo khoa học: "A Computational Model of Text Reuse in Ancient Literary Texts" potx
... definitive answers, it can serve as a supplement to linguistic and literary-critical approaches to text-reuse analysis, and can be especially helpful when dealing with a large amount of candidate source ... proposed a text-reuse model for ancient literary texts, with novel features that account for source alternation patterns These features were validated on the Lukan Passion Narrative, an instance of ... This standard bag -of- words approach is appropriate for Greek, a relatively free word-order language Figure plots this feature on Luke and Mark Non-derived verses are assigned a constant score...
Ngày tải lên: 08/03/2014, 02:21
Báo cáo khoa học: "A Computational Model of Social Perlocutions" docx
... compliance, anger, or both, and similarly, anger can be caused by a variety of other acts, such as issuing a threat In Figure 3, both praising and apologizing are examples of acts that can increase ... This approach can be viewed as a form of reactive planning LetterGen can be viewed as having a simple goal (communicate a particular belief to the hearer), forming a plan (finding a set of speech ... of The reason is that too many queries makes the program loses its appeal as a work-saving device A related limitation is that its model of the speaker's goals is static, rather than dynamic (e.g.,...
Ngày tải lên: 08/03/2014, 05:21
Báo cáo khoa học: "A COMPUTATIONAL MODEL OF THE SYNTAX-PROSODY INTERFACE IN TOKYO JAPANESE" doc
... Japanese: An Autosegmental Theory of Tonology Kaitakusha, Tokyo Kaplan, Ronald and Joan Bresnan (1982) Lexical Functional Grammar: A Formal System for Grammatical Representation in The Mental ... (laugh-and), amaku (sweetly) verbal - adnominal warau (that laughs), amakatta (that was sweet) The syntactic rules define three ways of building signs (3) shows rule A (essentially function application) ... phonetically as the domain of downstep; the precise character of major phrases is a point at issue in this paper The diagram is annotated according to the notation of Pierrehumbert (1980) The pitch accent...
Ngày tải lên: 09/03/2014, 01:20
The Production of Child Health in Kenya: A Structural Model of Birth Weight potx
... similarly high rates of tetanus vaccination in low-income countries Dow et al.(1999) report tetanus vaccination rates of the same orders of magnitude for Malawi, Tanzania, Zambia and Zimbabwe ... holding Panels 2D and 2E show sample means for one environmental variable: long-term annual rainfall and its interactions with cattle and land These variables are used to capture effects of natural ... demographics Focusing on the IV estimates, it can be seen that the birth weight of babies in rural areas is lower than that of urban babies, and that male infants are heavier than female infants.5...
Ngày tải lên: 14/03/2014, 09:20
A structural model of one dimensional thin silica nanowires
... smaller gaps of SU-2MR chains indicate higher chemical reactivities, facilitating the continuous growth of the chains Hence, the SU-2MR chain may be a more reasonable growth model of 1D silica ... chains It is proposed to be a more appropriate growth model of 1D silica nanowires because of their higher energetic and thermal stabilities and chemical reactivity than those of ES-2MR chains ... surfaces of the HOMO and LUMO states of the SU-2MR chain at n = 12, respectively The energy gap is a signature of the chemical reactivity of a system Compared to the ES-2MR chains, the relatively...
Ngày tải lên: 16/03/2014, 15:03
Báo cáo khoa học: "A Rational Model of Eye Movement Control in Reading" pdf
... Optimization of policy parameters Searching directly for optimal values of α and β for our stochastic reading model is difficult because each evaluation of the model with a particular set of parameters ... 3: Mean number of timesteps taken to read a sentence and (natural) log probability of the true identity of the sentence ‘Accuracy’ for a range of values of α and β Values of α are not labeled, ... strings, AB and BA, and assume that the eyes can only get noisy information about the identity of one character at a time After obtaining a little information about the identity of the first character,...
Ngày tải lên: 23/03/2014, 16:20