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... Java code is PersonalJava compatible, can be found at http://www.javasoft.com/products/personaljava/ JavaTV JavaTV is an Application Program Interface (API) specifically designed for a digital ... and java.math for more advanced applications The Kada APIs have a total footprint of 460KB There are two sizes of Kada VM you can download: The Kada Compact VM for simple AWT or network applications ... can begin to determine all the variables, graphical elements, and other gameplay elements Ultimately, you should be able to create a game state a list of variables, or perhaps just an array of...

Ngày tải lên: 16/01/2014, 20:20

... collar, a pair of high-heeled pumps and a black coat over that All with an impeccable fit What made me unable to take my eyes off her was the fantastic way she was made up “You are a modern-day ... was always a pillar of support Anna was her one and only weakness I kissed both of them and it was obvious that my delight to see Anna again, was reciprocated My mother could not hide her happiness ... for small talk.” “It's a matter of practice,” said Moni Of doing often what may not be agreeable at first Eventually one gets the hang of it and may even enjoy it I never did go out as much as...

Ngày tải lên: 06/11/2012, 17:33

... mammalian evolution J Exp Med 1998, 188:1521-1528 Nieda M, Nicol A, Koezuka Y, Kikuchi A, Takahashi T, Nakamura H, Furukawa H, Yabe T, Ishikawa Y, Tadokoro K, et al.: Activation of human Valpha24NKT ... 2001, 194:1789-1799 Furlan R, Bergami A, Cantarella D, Brambilla E, Taniguchi M, Dellabona P, Casorati G, Martino G: Activation of invariant NKT cells by alphaGalCer administration protects mice ... Miyamoto K, Hashimoto H, Yamamura T, Miyake S: Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide Arthritis...

Ngày tải lên: 09/08/2014, 06:22

... China(Taiwan) Asian Casson AG[21] 2003 Canada Caucasian Roth MJ[32] 2004 China Asian Casson AG[20] 2006 Canada Caucasian Cai L[25] 2006 China Asian Murphy SJ[33] 2007 Irish Caucasian Canova C[19] ... Engstrom A, Kozarich JW, Mannervik B: Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases ... analysis Data Extraction Two investigators independently extracted data and reached a consensus on all of the items Data extracted from these articles included the first author’s name, year of...

Ngày tải lên: 25/10/2012, 11:40

... thrombocythemia Neoplasma 2003;50:447-51 Akiyama T, Matsunaga T, Terui T, Miyanishi K, Tanaka I, Sato T, Kuroda H, Takimoto R, Takayama T, Kato J, Yamauchi N, Kogawa K, Sakamaki S, Hirayama Y, Kohda K, ... thrombocythaemia Leuk Lymphoma 2000;36:533-8 Tomita N, Motomura S, Sakai R, Fujimaki K, Tanabe J, Fukawa H, Harano H, Kanamori H, Ogawa K, Mohri H, Maruta A, Kodama F, Ishigatsubo Y, Tahara T, Kato ... 29 Vannucchi AM, Bianchi L, Paoletti F, Pancrazzi A, Torre E, Nishikawa M, Zingariello M, Di Baldassarre A, Rana RA, Lorenzini R, Alfani E, Migliaccio G, Migliaccio AR A pathobiologic pathway...

Ngày tải lên: 03/11/2012, 10:52

... vanadate stock solution was prepared as a 200 mM solution of sodium orthovanadate (pH 10) Pervanadate was prepared as a ·100 stock by adding 50 lL of 200 mM sodium orthovanadate and 1.6 lL of ... with an antibody against total tau revealed decreased electrophoretic mobility of tau, with the appearance of an  68-kDa tau species in wild-type and all of the mutant forms of tau except for YallF ... or ANOVA with GRAPHPAD PRISM 5.0 (GraphPad Software Inc., La Jolla, CA, USA) Data are presented as mean ± standard error of the mean (SEM) Tyrosine phosphorylation-dependent tau–Fyn binding Acknowledgements...

Ngày tải lên: 14/02/2014, 14:20

... phosphoserine-473 Akt polyclonal antibody (Biosource International, Camarillo, CA, USA) to detect active Akt kinase, as well as a separate Akt polyclonal antibody (Cell Signaling Technology, Danvers, MA, USA) ... supplementary material is available online: Fig S1 Proposed role of the P2Y12 receptor in regulating Ca2+ signaling and platelet procoagulant activity This material is available as part of the online article ... phosphate [46] SERCA activity represented the ATP- and thapsigargin-sensitive phosphatase activity Measurement of Akt activation Akt activation was measured by western blot analysis, using a phosphoserine-473...

Ngày tải lên: 18/02/2014, 16:20

... ubiquitination of Rac1L61 and Rac1b (left panel) HEK293 cells were transfected with a combination of expression plasmids of HA–Rac1L61, HA– Rac1bWT, HA–Rac1bL61 and 6His–myc–Ub as indicated Proteasomal ... Visvikis et al Fig Ubiquitination and proteasomal degradation of Rac1L61 and Rac1b (A) Activated Rac1L61 undergoes ubiquitination in HEK293 cells Ubiquitination of Rac was assessed by transfecting ... that the stimulation of Rac1-dependent pathways may, in some way, activate the Rac1 ubiquitination machinery As Rac1b has been shown to display reduced capacity to bind POSH [28] and to activate...

Ngày tải lên: 18/02/2014, 16:20

... (Quebec, Canada) and rabbit polyclonal antibody raised against ERK1 and ERK2 (anti-ERK1/2) was purchased from Santa Cruz (Le Perray-en-Yveline, France) Rabbit polyclonal antibody raised against the ... data DM conceived the study, participated in its design and coordination, statistical analysis and interpretation of data and drafted the manuscript FLB, SF and DM read and approved the final ... the Agricultural and Scientific Research agencies (approval number A 37801) and conducted in accordance with the guidelines for Care and Use of Agricultural Animals in Agricultural Research and...

Ngày tải lên: 05/03/2014, 17:20

... Gardens and in the adjacent Canberra Nature Park (c km2 ), and there was dispersal both into and out of the Gardens The Gardens occupy an area of 40 ha, of which 27 are planted with native Australian ... was used on group size and territory quality (categorical variables), and male age and age squared (continuous variables) Age and age-squared were used in case the effect of male age was not a ... that of breeding as a yearling in a pair, as expected if group size affected the success of yearlings (compare with Fig 4a) The probability of success was 0·25 as a yearling in a pair to 0·58 as...

Ngày tải lên: 14/03/2014, 16:20

... Arab fears of Shi’ite ascendancy and sectarian strife in their media outlets to curry favor for what is essentially a classic balance -of- power strategy against Iran Regarding a U.S attack against ... significant arsenal of short- and medium-range ballistic missiles that can reach the small Persian Gulf states, Afghanistan, Israel, eastern Turkey, and most of Saudi Arabia Although these missiles are ... Camp Ashraf in Iraq and the appearance on the U.S.-sponsored Voice of America of Abdulmalik Riga, the head of a Baluchi militant group active in Iran’s underdeveloped province of Sistan-va Baluchestan.20...

Ngày tải lên: 15/03/2014, 21:20

... crystallographic data are extremely rare, maybe because the technique is so heavily based on calculations that data are not easy to fake Perhaps the best known case of that sort was a discovery that ... 333–346 ´ 72 Bujacz G, Jaskolski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA & Skalka AM (1996) The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues ... statistical factors, reflecting the estimated accuracy of individual amplitudes and phases Because all data used to compute maps (both amplitudes and phases) contain a degree of error, the maps also...

Ngày tải lên: 16/03/2014, 06:20

... essentially the same in both cases and, above all, no appreciable differences in the rates of disappearance of ATP or appearance of Ino were observed Theoretical approach mathematical simulation of ... the above values, application of the MATHEMATICA-3.0 program [37] to the case of a reaction mixture containing ATP, ADP and AMP (at the same concentrations as those present in the experimental approach, ... towards inosine, and that the adenylic charge value decreases, from a standard value of around 0.8 to a value of around 0.4 Similar results to those obtained with galactose, concerning variations...

Ngày tải lên: 17/03/2014, 10:20

... glioma-associated protein SETA interacts with AIP1/ Alix and ALG-2 and modulates apoptosis in astrocytes J Biol Chem 275, 19275–19281 14 Watanabe, S., Take, H & Takeda, K., Yu, Z.X., Iwata, N & Kajigaya, ... degraded via the Ub-proteasome pathway [24,25] Re-probing of the membrane with anti-(b-catenin) Ig clearly demonstrated the accumulation of ubiquitinated forms of b-catenin upon ALLN and lactacystine ... N-Ac-Leu-Leu-norLeucinal (ALLN) and lactacystin were purchased from Sigma and Calbiochem, respectively Rabbit polyclonal anti-hemagglutinin (HA) Ig and anti-Cbl Ig were purchased from Santa Cruz...

Ngày tải lên: 17/03/2014, 23:20

... accumulation of amyloid per se that is pathological, leading to organ failure and eventual death [5–7] Smaller amounts of amyloids accumulated in sensitive locations, such as the cornea, can also lead to ... use as functional amyloid, serving as structural anchoring material for a range of purposes ranging from biofilm formation to a matrix to anchor melanin as well as for the reduction of interfacial ... Yamaguchi K, Takahashi S, Kawai T, Naiki H & Goto Y (2005) Seeding-dependent propagation and maturation of amyloid fibril conformation J Mol Biol 352, 952–960 Petkova AT, Leapman RD, Guo Z, Yau...

Ngày tải lên: 23/03/2014, 03:20

... trifluoroacetic acid Absorbance was measured at 280 nm, and the flow rate was 0.3 mL ⁄ Statistical analysis Data from three independent experimental groups are presented as mean values ± standard deviation ... inhibition of the early stage of amylin aggregation As the incubation proceeds, increasing amounts of amylin–insulin complex can accumulate and serve as a nucleus for fibrillization of the remaining ... was incubated with amylin to evaluate its effect on amylin aggregation Samples were incubated at 37 °C for 72 h with shaking, and were taken for ThT assays, light scattering assays and HPLC analysis...

Ngày tải lên: 23/03/2014, 04:21

... and biotools software from Bruker A peptide mass tolerance of ± Da, a fragment mass tolerance of ± Da and one maximal missed cleavage side were accepted The carbamidomethylation of cysteine and ... Yoshimura Y, Yamazaki N, Yoshimura Y, Yamauchi T, Kataoka M, Nagata T, Terada H et al (2006) VDAC1, having a shorter N-terminus than VDAC2 but showing the same migration in an SDS–polyacrylamide gel, ... Macromolecular organization of pyruvate and alpha-ketoglutarate dehydrogenase complexes isolated from beef kidney mitochondria Proc Natl Acad Sci USA 56, 534–541 22 Tanaka N, Koike K, Hamada...

Ngày tải lên: 23/03/2014, 06:20

... G-actin was similar for various actin iso-forms [rabbit alpha skeletal, bovine alpha cardiac, bovine aortic and scallop (Pecten) muscles], and established conditions under which the ELISA assay ... presence of mM calcium (apparent Kd ¼ 30 nM), and in the presence of mM EGTA, no binding occured In contrast, at pH 5.7 and with mM EGTA, a weak interaction was observed and a Kd of about lM was estimated ... G4–6 domains were labeled by Oregon green isothiocyanate and increasing concentrations of G2 were added An apparent Kd of 0.5 lM was obtained at pH 5.7, a value similar to that reported previously...

Ngày tải lên: 23/03/2014, 21:20

... social capital was also applied to public health to explain health disparities Social capital is actually considered as a potential explanatory factor of an individual’s health status since social ... self-assessed health status and to have a regular social participation on whole population Finding indicates that after instrumentation, social capital (that is to say having a regular social participation) ... beneficial causal influence of social participation on health status Individuals retired, disabled or homemakers aged more than 55 years old take advantage of social participation because they have...

Ngày tải lên: 28/03/2014, 20:20